Genes glycine. Medical search. Frequent questions

A perennial living across the Outback in extremely hot and dry conditions, it is being studied for its potential to improve the cultivated soybean (Glycine max). (wikipedia.org)
Genomic resequencing of soybean (Glycine max (L.) Merr. (ufrgs.br)
The objective of this work was to resequence and assemble the genome of two contrasting soybean cultivars to soil flooding, to evaluate the expression of candidate genes and to identify non-synonymous changes in these gene sequences. (ufrgs.br)
We compared gene expression patterns in soybean root cells being fed upon by SCN in both SCN-resistant and susceptible soybean to determine if we could identify genes that are highly expressed in resistant root cells and not highly expressed in susceptible cells. (usda.gov)
These genes may provide clues as to how soybean cells can be resistant to SCN. (usda.gov)
We identified several genes that were highly expressed in SCN-resistant compared to susceptible soybean root cells using sophisticated molecular biology techniques. (usda.gov)
Syncytial cells in soybean (Glycine max cultivar [cv. (usda.gov)
Peking) roots infected by incompatible (I) and compatible (C) populations of soybean cyst nematode [SCN] (Heterodera glycines) were collected using laser capture microdissection. (usda.gov)
Gene transcript abundance was assayed using an Affymetrix® soybean GeneChip® containing 37,744 probe sets. (usda.gov)
Thus, Gregory Pearce and colleagues at Washington State University isolated a peptide from soybean leaves that even nanomolar concentrations have induced pH of soybean ( Glycine max ) suspension media in a period of 10 minutes. (isaaa.org)
When Gm SubPep is supplied to soybean cultures, it was found to induce the expression of defense genes. (isaaa.org)
Efficient Isolation and Gene Transfer of Protoplast in Korean Soybean (Glycine Max (L.) Merr. (scirp.org)
Glufosinate tolerance in W62 and W98 soybean lines is the result of introducing a gene encoding the enzyme phosphinothricin-N-acetyltransferase (PAT) isolated from the common aerobic soil actinomycete, Streptomyces hygroscopicus, the same organism from which glufosinate was originally isolated. (cbd.int)
The PAT encoding gene (bar) was introduced into the soybean genome by micro-particle acceleration (biolistic) transformation, and the resulting soybean lines displayed field tolerance to phosphinothricin-containing herbicides, thereby permitting farmers to use this herbicide for weed control in soybean cultivation. (cbd.int)
Transcriptome analysis of soybean (Glycine max) root genes differentially expressed in rhizobial, arbuscular mycorrhizal, and dual symbiosis. (harvard.edu)

Our analyses identified differentially expressed genes in syncytial cells microdissected from roots undergoing I and C reactions. (usda.gov)
There were 3954 correlations and a total of 15 correlations for differentially expressed proteins (DEPs) and differentially expressed genes (DEGs) from proteomics and transcriptomics. (hindawi.com)

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene. (jax.org)
Mutations in the GATM gene cause arginine:glycine amidinotransferase deficiency. (medlineplus.gov)
GATM gene mutations impair the ability of the arginine:glycine amidinotransferase enzyme to participate in creatine synthesis, resulting in a shortage of creatine. (medlineplus.gov)
which means both copies of the gene in each cell have mutations. (medlineplus.gov)
Biallelic germline mutations in the base excision repair gene MYH have been reported in patients with multiple colorectal adenomas and cancer and in sporadic FAP patients not showing a detectable APC germline mutation. (nih.gov)
From Genes to Genetic Diseases: What Kinds of Mutations Matter? (sciencebuddies.org)
In this science project, you will explore online genetic databases to identify how a mutation in a gene can result in a dysfunctional protein, and how other mutations may have no effect at all. (sciencebuddies.org)
Determine why some gene mutations cause genetic diseases, but others do not. (sciencebuddies.org)
Mutations of the BRAF gene can cause certain inherited diseases and birth defects. (news-medical.net)
More than 700 mutations in the COL7A1 gene have been identified in people with dystrophic epidermolysis bullosa, a condition that causes the skin to be very fragile and to blister easily. (medlineplus.gov)
The recessive types of dystrophic epidermolysis bullosa (RDEB) result from mutations in both copies of the COL7A1 gene in each cell. (medlineplus.gov)
Most of the COL7A1 gene mutations responsible for RDEB-sev gen result in production of abnormally short pro-α1(VII) chains that cannot form type VII collagen. (medlineplus.gov)
A milder, dominant form of dystrophic epidermolysis bullosa (DDEB) results from mutations in one copy of the COL7A1 gene in each cell. (medlineplus.gov)
Mutations that substitute other amino acids for glycine in this region can disrupt the triple-stranded structure of type VII collagen. (medlineplus.gov)
Although they are most commonly associated with DDEB, mutations that substitute glycine amino acids in the triple helical domain can also cause RDEB. (medlineplus.gov)
It is unclear how COL7A1 gene mutations are associated with an increased risk of a certain cancer called squamous cell carcinoma in people with dystrophic epidermolysis bullosa, particularly RDEB-sev gen. (medlineplus.gov)
Mutations in the COL7A1 gene can also cause a rare condition called epidermolysis bullosa with congenital localized absence of skin (also known as Bart syndrome or aplasia cutis congenita type VI). (medlineplus.gov)
A variety of mutations in the ALDH7A1 gene have been found to cause pyridoxine-dependent epilepsy. (medlineplus.gov)
We analysed 50 probands with a family history of breast and/or ovarian cancer for germline mutations in the coding region of the BRCA1 candidate gene, using single-strand conformation polymorphism (SSCP) analysis on PCR-amplified genomic DNA. (nih.gov)
In addition, we found two missense mutations, one of which changes the final cysteine of the BRCA1 zinc finger motif to glycine. (nih.gov)
The heterogeneity of mutations, coupled with the large size of the gene, indicates that clinical application of BRCA1 mutation testing will be technically challenging. (nih.gov)
Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. (thermofisher.com)
Mutations occurring in the wrong place of the MT-CYB gene can result in exercise intolerance and multi-system pathologies. (eupedia.com)
Deleterious mutations would be so debilitating that they would be eliminated from the gene pool within a few generations. (eupedia.com)
The purpose of this analysis is to show that evolutionary advantageous mutations in the Coenzyme Q gene are rare, but when they do occur they usually results in major expansions of the affected mitochondiral lineages, as attested by the high frequency of the newly founded haplogroups and the plethora of subclades downstream of the new mutation. (eupedia.com)
In fact, subclades that did not develop new mutations in the MT-CYB gene did not prosper and have become exceedingly rare nowadays. (eupedia.com)
Achondrogenesis results from mutations in the TRIP11 (ACGIA), SLC26A2 (ACGIB), and COL2A1 (ACGII) genes, with achondrogenesis types IA and IB being autosomal recessive conditions and achondrogenesis type II most often being sporadic. (medscape.com)
Classification of type IB as a separate group has been confirmed by the discovery of its association with mutations in the diastrophic dysplasia sulfate transporter ( DDST ) gene, making it allelic with diastrophic dysplasia. (medscape.com)
Type IB is caused by recessive mutations of the diastrophic dysplasia sulfate transporter gene ( SLC26A2 ), and type II is caused by autosomal dominant mutations of the type II collagen gene ( COL2A1 ). (medscape.com)
Several heritable osteochondrodysplasias have now been recognized as members of the family of type II collagen disorders, all of which result from dominant mutations in the COL2A1 gene. (medscape.com)
BACKGROUND: : Inherited mutations in the CDKN2A tumor suppressor gene, which encodes the p16(INK4a) protein, and in the cyclin-dependent kinase 4 (CDK4) gene confer susceptibility to cutaneous malignant melanoma. (lu.se)
We analyzed families with two or more cases of melanoma for germline mutations in CDKN2A and CDK4 to elucidate the contribution of these gene defects to familial malignant melanoma and to the occurrence of other cancer types. (lu.se)
METHODS: : The entire CDKN2A coding region and exon 2 of the CDK4 gene of an affected member of each of 52 families from southern Sweden with at least two cases of melanoma in first- or second-degree relatives were screened for mutations by use of polymerase chain reaction-single-strand conformation polymorphism analysis. (lu.se)

Specifically, we hypothesize the candidate gene, CG10804, is a potential gene that encodes for a glycine transporter in Drosophila. (utep.edu)
For example, in cystic fibrosis there is a mutation in a gene, called the CFTR gene, that encodes for a channel that controls the flow of particles in cells. (sciencebuddies.org)
Cystic fibrosis is caused by a mutation in the CFTR gene, which encodes for a chloride channel that is important for regulating water flow into, and out of, the cells. (sciencebuddies.org)
The gene that encodes THAP3 contains roughly 10,721 bases and maps to human chromosome 1p36.31. (fishersci.com)
This gene encodes the L protein of the mitochondrial glycine cleavage system. (thermofisher.com)

phosphoribosylamine--glycine ligase [Bacillus anthracis str. (yeastrc.org)
phosphoribosylamine--glycine ligase [Colwellia psychrerythraea 34H], gi. (yeastrc.org)
phosphoribosylamine--glycine ligase [Ehrlichia chaffeensis str. (yeastrc.org)
phosphoribosylamine--glycine ligase [Neorickettsia sennetsu str. (yeastrc.org)

Edvardson S, Korman SH, Livne A, Shaag A, Saada A, Nalbandian R, Allouche-Arnon H, Gomori JM, Katz-Brull R. l-arginine:glycine amidinotransferase (AGAT) deficiency: clinical presentation and response to treatment in two patients with a novel mutation. (medlineplus.gov)
In this study, the prevalence of the common Y165C and G382D germline variants of the MYH gene was examined in 70 FAP/AAPC patients with no detectable APC mutation and a family history compatible with recessive inheritance. (nih.gov)
The B-Raf gene has two hotspots for mutation. (news-medical.net)
While analysing the mtDNA phylogeny, I noticed that most of the common, successful mitochondrial haplogroups were defined by a new mutation in the Coenzyme Q - cytochrome c reductase gene ( MT-CYB ) encoding the Cytochrome b protein, located between positions 14,747 and 15,887 in the mtDNA sequence. (eupedia.com)
Here is the list of the main haplogroups containing a mutation in the MT-CYB gene. (eupedia.com)
Achondrogenesis II results from heterozygosity for a new dominant mutation in the COL2A1 gene at the chromosomal locus 12q8.11-q13.2. (medscape.com)
Now, a research team in Lund has finally pinpointed a mutation in the ZFHX3 gene as the cause of the disease. (lu.se)
The mutation leads to a protein with an abnormally long repetition of the amino acid glycine, which likely is the reason for an accumulation of proteins in nerve cells, causing imbalance in the nervous system. (lu.se)
Nine families carried an identical alteration consisting of the insertion of arginine at position 113 of p16(INK4a), and one carried a missense mutation, in which the valine at position 115 was replaced with a glycine. (lu.se)

RAF genes encode serine and threonine kinase proteins downstream of Ras in the pathway. (news-medical.net)

The male sterilizing factors usually consist of unusual genes or open reading frames encoded by the mitochondrial genome. (frontiersin.org)
In the majority of cases, Rf genes produce proteins that act directly on the CMS conferring mitochondrial transcripts by binding them specifically and promoting processing events. (frontiersin.org)
The male sterilizing factors are produced by recombination of the mitochondrial genome and consist of unusual genes or open reading frames (ORFs) that usually contain a portion of functional mitochondrial genes and sequences of unknown origin ( Hanson and Bentolila, 2004 ). (frontiersin.org)
In the majority of cases, Rf genes produce proteins that bind specifically to the CMS conferring transcripts in the mitochondria and promote processing events leading to a strong reduction in the production of mitochondrial CMS-inducing proteins (reviewed in Chen and Liu, 2014 ). (frontiersin.org)
Positive selection for beneficial polymorphisms in the MT-CYB gene appear to have played a major role in mitochondrial evolution in human populations. (eupedia.com)

G3: Genes, Genomes, Genetics. (wikipedia.org)

The study of glycine transporters has been neglected compared to other members of the Solute Carrier 6 (SLC6) family of proteins, such as the dopamine and serotonin transporters, even though they are just as crucial to survival. (utep.edu)
Basic understanding of what genes, DNA, and proteins are. (sciencebuddies.org)
In syncytial cells from I roots at three days post infection (dpi), genes encoding lipoxygenase, heat shock protein 70, and superoxidase dismutase were elevated almost 10-fold or more, while genes encoding several transcription factors and DNA binding proteins were also elevated, albeit at lower levels. (usda.gov)
Silks are composed principally of proteins with a predominance of alanine, serine and glycine and silk proteins are able to undergo irreversible transformations from soluble protein to insoluble fibres. (bioone.org)

However, uptake experiments demonstrated an insignificant amount of glycine transport from CG10804, suggesting this may not be a glycine transporter in D. melanogaster. (utep.edu)

We believe this organism possesses a glycine transporter because a glycine receptor has been identified and characterized. (utep.edu)
80%) and biological pathways (such as adipocytokine, Notch, Hedgehog and NOD-like receptor signaling) were not identified by previous gene array studies. (mdpi.com)
For example, cerebellar granule cells express six subunit genes abundantly (α 1 , α 6 , β 2 , β 3 , γ 2 , and δ), and so they probably have several distinct GABA A receptor subtypes of unknown subunit stoichiometry. (jneurosci.org)

Furthermore, gene expression, immunofluorescence and western blot analyses seemingly demonstrate that CG10804 is localized at the plasma membrane of Porcine Aortic Endothelial (PAE) cells, which fulfills a requirement as a member of the SLC6 family. (utep.edu)
Detection of Human Glycine N-methyltransferase/GNMT by Western Blot. (rndsystems.com)

3. Those who are identified as developmental epileptic encephalopathy (DEE) (currently known DEE-related 96 genes and MECP2, etc. (who.int)
4. Identify metabolic epilepsy (GLUT1 gene defect), glycine encephalopathy, etc. (who.int)

The reports on base sequences of spider silk protein genes have gained importance as the mechanical properties of silk fibers have been revealed. (bioone.org)
Here, we present evidence that the promoter regions of intellectual disability-associated genes are uniquely enriched in LTR sequences of the MER41 HERVs. (biorxiv.org)
Of note, functionally-relevant differences between humans and chimpanzees are observed regarding the 3 main components of this pathway: i) the protein sequences of immunes TFs binding MER41 LTRs, ii) the insertion sites of MER41 LTRs in the promoter regions of ID-associated genes and iii) the protein sequences of the targeted ID-associated genes. (biorxiv.org)

The gene ontology (GO) terms associated with monooxygenase, iron binding, and passive transmembrane transporter activities were significantly enriched in four out of six resistant vs. susceptible comparisons while serine protease activity was elevated in all insecticide-resistant groups relative to the susceptible strain. (cdc.gov)

In a gene, if a single DNA nucleotide is mutated, for example from an adenine (A) to a guanine (G), this may cause the wrong amino acid to be made. (sciencebuddies.org)
It is made up of a pattern of protein building blocks (amino acids) in which every third amino acid is a glycine. (medlineplus.gov)
it replaces the amino acid glutamine with the amino acid glycine at position 399 in the antiquitin protein (written as Glu399Gln or E399Q). (medlineplus.gov)

TDP-43 regulates RNA metabolism, trafficking, and localization of thousands of target genes. (nature.com)
Many genes are involved in starch biosynthesis and there is limited natural variation with regards to starch metabolism in cassava compare to other crops such as maize. (scialert.net)

Various uncharacterized D. melanogaster genes were analyzed by homology analysis, and it was determined CG10804 was the most likely candidate to encode for a glycine transporter based on the number of conserved residues with mammalian glycine transporters. (utep.edu)
However, future studies aim to utilize an insect cell line instead of the mammalian PAE cells, before definitively ruling out CG10804 as the Drosophila glycine transporter. (utep.edu)

GXD's primary emphasis is on endogenous gene expression during development. (jax.org)
These observations demonstrate that gene expression is different in syncytial cells as compared to whole roots infected with nematodes. (usda.gov)
Our observations also show that gene expression is different between syncytial cells that were isolated from I and C roots and that gene expression is changing over the course of syncytial cell development as it matures into a functional feeding site. (usda.gov)
Genes whose expression levels rise and fall similarly in a large set of samples, may be considered coexpressed. (mdpi.com)
Simple protoplast isolation system for gene expression and protein interaction studies in pineapple (Ananas comosus L. (scirp.org)
The main tool used in transcriptomics is total RNA sequencing, which is a powerful tool for analyzing gene expression changes in response to various environmental stresses [ 27 ]. (hindawi.com)
Here, we applied Illumina RNA-Seq to study the gene expression patterns associated with resistance to three widely used insecticides (malathion, alphacypermethrin, and lambda-cyhalothrin) in Ae. (cdc.gov)
If expression of a trait requires only one copy of a gene (one allele). (msdmanuals.com)

Cytochrome P450s were the most overexpressed detoxification genes across all resistant phenotypes. (cdc.gov)

Detects human Glycine N-methyltransferase/GNMT in direct ELISAs and Western blots. (rndsystems.com)
PVDF Membrane was probed with 1 µg/mL of Human Glycine N-methyltransferase/GNMT Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6526) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016 ). (rndsystems.com)
A specific band was detected for Glycine N-methyltransferase/GNMT at approximately 33 kDa (as indicated). (rndsystems.com)
GNMT (glycine N-methyltransferase) is a cytoplasmic homotetramer of 33 kDa units that converts S-adenosylmethionine to N-methylglycine (sarcosine), also producing S-adenosylhomocysteine. (rndsystems.com)

Ressequenciamento genômico de soja (Glycine max (L.) Merr. (ufrgs.br)
O cultivo da soja (Glycine max (L.) Merr. (ufrgs.br)
한국 콩 (Glycine Max (L.) Merr. (scirp.org)

The glycine cleavage system catalyzes the degradation of glycine. (xenbase.org)

The GATM gene provides instructions for making the enzyme arginine:glycine amidinotransferase. (medlineplus.gov)

The ALDH7A1 gene provides instructions for making an enzyme called α-aminoadipic semialdehyde (α-AASA) dehydrogenase, also known as antiquitin. (medlineplus.gov)

The ALDH7A1 gene is a member of the aldehyde dehydrogenase (ALDH) gene family. (medlineplus.gov)

We further investigate if plants or the microbial biomass exhibit preferences for certain nitrogen forms (glycine, nitrate, and ammonium) to gain insight into nitrogen partitioning in invaded communities. (who.int)

TDP-43 is a highly conserved, ubiquitously expressed, multifunctional nucleic acid-binding protein composed of two RNA recognition motifs (RRM), nuclear localization (NLS) and export signals (NES), and a carboxy-terminal glycine rich region. (nature.com)

Our genes are made up of hundreds to millions of building blocks, called DNA nucleotides, and if just a single nucleotide of DNA becomes mutated it might cause a devastating genetic disease. (sciencebuddies.org)
Аутосомно-рецесивний Genetic disorders determined by a single gene (Mendelian disorders) are easiest to analyze and the most well understood. (msdmanuals.com)

B-Raf is a protein encoded by the BRAF gene and is involved in the RAS/MAPK pathway, which regulates cellular growth and division. (news-medical.net)

We used a bioinformatics approach to determine any conserved residues essential for glycine, sodium, and chloride binding between our candidate gene and its mammalian counterpart. (utep.edu)
Based on the atomic coordinates of the human GlyT1 crystal structure, the amino acids that participate in glycine, sodium and chloride binding were found to be identical to the corresponding residues in the CG10804 protein. (utep.edu)

Genes (Basel). (harvard.edu)

In this step, a compound called guanidinoacetic acid is produced by transferring a cluster of nitrogen and hydrogen atoms called a guanidino group from arginine to glycine. (medlineplus.gov)

Therefore, distribution of ESBL genes, plasmids and strain genotypes in Escherichia coli obtained from poultry and retail chicken meat in the Netherlands was determined and defined as 'poultry-associated' (PA). (who.int)
Isolates were analysed using an ESBL-specific microarray, sequencing of ESBL genes, PCR-based replicon typing of plasmids, plasmid multi-locus sequence typing (pMLST) and strain genotyping (MLST). (who.int)

In syncytial cells formed during the C interaction at three dpi, genes encoding prohibitin, the epsilon chain of ATP synthase, allene oxide cyclase and annexin were highly expressed. (usda.gov)
The COL7A1 gene provides instructions for making a protein called pro-α1(VII) chain that is used to assemble a larger protein called type VII collagen. (medlineplus.gov)

E2F site in the essential promoter region does not confer S phase-specific transcription of the ABCC10 gene in human prostate cancer cells. (nih.gov)
Transcriptomics focuses on gene transcription and regulation of transcription in cells [ 25 , 26 ]. (hindawi.com)
Interestingly, ID-associated genes exhibit promoter-localized MER41 LTRs that harbor TF binding sites (TFBSs) for not only STAT1 but also other immune TFs such as, in particular, NFKB1 (Nuclear Factor Kappa B Subunit 1) and STAT3 (Signal Transducer And Activator Of Transcription 3). (biorxiv.org)

Search on a gene symbol or gene name keyword(s). (jax.org)

Arginine:glycine amidinotransferase deficiency is an inherited disorder that primarily affects the brain. (medlineplus.gov)
Children with arginine:glycine amidinotransferase deficiency may not gain weight and grow at the expected rate (failure to thrive), and have delayed development of motor skills such as sitting and walking. (medlineplus.gov)
The prevalence of arginine:glycine amidinotransferase deficiency is unknown. (medlineplus.gov)
The effects of arginine:glycine amidinotransferase deficiency are most severe in organs and tissues that require large amounts of energy, especially the brain. (medlineplus.gov)

Subsequently, the proportion of E. coli isolates with PA ESBL genes, plasmids and strains was quantified in a representative sample of clinical isolates. (who.int)

The Human Genome Project has estimated that the human genome contains around 20,000 to 25,000 genes . (sciencebuddies.org)
The powerful high throughput screening approach, developed in my group, enables me to study all the possible combinations between a phenotypic reporter of choice and a collection of gene mutants throughout the yeast genome in a few months (while a conventional manual test would take more than several decades). (gu.se)

Every gene in the human body consists of DNA (deoxyribonucleic acid). (sciencebuddies.org)
There are three human RAF genes: ARAF, CRAF-1, and BRAF. (news-medical.net)
Six ESBL genes were defined as PA (bla(CTX-M-1) , bla(CTX-M-2) , bla(SHV-2) , bla(SHV-12) , bla(TEM-20) , bla(TEM-52) ): 35% of the human isolates contained PA ESBL genes and 19% contained PA ESBL genes located on IncI1 plasmids that were genetically indistinguishable from those obtained from poultry (meat). (who.int)

The ALDH7A1 gene is found on chromosome 5 . (medlineplus.gov)

Recently, we reported that functional wheat inositol penta kis phosphate kinase ( TaIPK1 ) is involved in PA biosynthesis, however, the functional roles of the IPK1 gene in wheat remains elusive. (frontiersin.org)

The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. (medlineplus.gov)
Achondrogenesis IA appears to be autosomal recessive, but the mutant gene is still unknown. (medscape.com)

The entire coding region of the MYH gene was analyzed in Y165C or G382D heterozygous patients. (nih.gov)

These genes provide instructions for producing enzymes that alter molecules called aldehydes. (medlineplus.gov)

These data are consistent with a tumour suppressor model, and support the notion that this candidate gene is in fact BRCA1. (nih.gov)

Anatomy2

Organisms3

Diseases1

Chemicals and Drugs49

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Phenomena and Processes14

Technology, Industry, Agriculture1

Information Science3

Soybean15

Differentially expressed genes2

Mutations33

Encodes5

PHOSPHORIBOSYLAMINE--GLYCI4

Mutation9

Serine and threonine1

Mitochondrial5

Genetics1

Proteins4

Uptake1

Receptor3

Western blot2

ENCEPHALOPATHY2

Sequences3

Ontology1

Amino acid3

Metabolism2

Transporter2

Expression8

Phenotypes1

GNMT4

Merr3

Cleavage1

Making the enzyme1

Enzyme1

Dehydrogenase1

Ammonium1

Localization1

Genetic2

Pathway1

Chloride2

Basel1

Compound1

Strain2

Chain2

Transcription3

Symbol1

Deficiency4

Coli1

Genome2

Human3

Chromosome1

Biosynthesis1

Autosomal recessive2

Coding region1

Molecules1

Candidate gene1