1000 mg/kg bw/d in a three-generation reproduction toxicity study of male and female rats, DePass (1986). (europa.eu)
In the two-generation oral reproductive toxicity study with the test substance (HCl), the NOAEL for general systemic toxicity was set at 300 mg/kg bw/day based on reduced food consumption and/or body weight gain, as well as organ weight changes unaccompanied by histopathological findings. (europa.eu)
Evaluation of a two-generation reproduction toxicity study adding endpoints to detect endocrine disrupting activity using lindane. (bvsalud.org)
Asexual reproduction1
Organisms with a life cycle that features alternation of generations with sexual and asexual reproduction. (eol.org)
Future generations6
We're happy to make these classics available again for future generations to enjoy! (google.com)
Tim Mulgan, Future People: A Moderate Consequentialist Account of Our Obligations to Future Generations , Oxford University Press, 2006, 402pp. (nd.edu)
He proposes that a version of rule consequentialism, however, is consistent with the cluster of plausible claims regarding future generations. (nd.edu)
Just as in the first half of the book, Mulgan begins with a cluster of intuitively plausible claims about public policy regarding future generations and argues that only rule consequentialism can accommodate them all. (nd.edu)
Individual obligations to future generations, Mulgan argues, must accommodate three "decisive intuitions:" It is wrong to gratuitously make future people suffer, it is wrong for the present generation to gratuitously make future generations suffer, and there is no general obligation to reproduce or not to reproduce. (nd.edu)
Additionally, the reproductive toxicity of IPA was assessed in a one-generation study in rats, conducted according to a method equivalent to OECD Test Guideline 415 and in compliance with GLP. (europa.eu)
Rats3
Interim Report on a 2-Generation Reproduction Study with Rats Conducted with 3,6,9-triethyl-3,6,9-trimethyl- triperoxoxane (CAS No. 24748-23-0) Solution in Isoparaffinic Hydrocarbons. (epa.gov)
XDE-795 (97.4% pure) was fed in diet to Sprague-Dawley rats (30/sex/dose) at 0, 5, 20 and 100 mg/kg/day, 7 days/week for 2 generations. (fluoridealert.org)
In the case of environmental toxins, Michael Skinner's reproductive biology lab at Washington State University Pullman in the United States first reported in 2005 that injecting pregnant rats with endocrine disruptor fungicide vinclozolin caused sperm abnormalities that persisted in the male progeny for at least 4 generations [4]. (i-sis.org.uk)
Sexual2
And there must also be a way of introducing change between one generation and the next through random mutation or by sexual recombination. (technologyreview.com)
When these steps are repeated over many countless generations, the individuals that emerge are those that have evolved to survive best in the given environment. (technologyreview.com)
Suffer1
The impacts can also linger as generations suffer declining health and reproduction. (nsidc.org)
Evolve1
Our findings provide novel empirical evidence that standing genetic diversity of phytoplankton resting stage allows populations to evolve rapidly (20-50 generations) and flexibly on timescales relevant for seasonal bloom progressions. (lu.se)
Genetic3
By applying the suggested breeding schemes, it is possible to achieve a genetic gain in growth of at least 10 % per generation. (europa.eu)
All kinds of life experiences, good and bad, from caring mothers to environmental toxins, leave epigenetic imprints that are passed on for generations afterwards (see [2, 3] Caring Mothers Strike Fatal Blow against Genetic Determinism , and Epigenetic Toxicology , SiS 41). (i-sis.org.uk)
Phytoplankton have short generation times, flexible reproduction strategies, large population sizes and high standing genetic diversity, traits that should facilitate rapid evolution under directional selection. (lu.se)
20221
Epidemic curve and reproduction number of monkeypox cases in Italy through July 8, 2022. (cdc.gov)
Study2
Preliminary Findings of a Two Generation Reproduction Study with Dichloride Salt of Monoethyleneglycol Polybutyleneoxide Diamine (XTJ-568). (epa.gov)
A one-generation study involving administration of IPA at concentrations ranging from 1.25 to 2.5% in drinking water did not identify a NOAEL. (europa.eu)
Curve2
B) Estimate of the net reproduction number over time from the epidemic curve by date of symptom onset. (cdc.gov)
A plurality of predetermined stored calibrated tone-reproduction curves are used, each predetermined stored calibrated tone-reproduction curve corresponding to a distinct media type and halftone type combination along with a plurality of predetermined relationships between each stored calibrated tone-reproduction curve and a reference media type and reference halftone type combination. (google.com)
Exposure1
These spermatozoa also experienced increased mitochondrial generation of reactive oxygen species after 1 week of exposure, with elevated DNA oxidation and fragmentation across all exposure periods. (nature.com)
Biology3
A vast literature on melatonin and vertebrate biology has accrued over the past 60 years since melatonin's discovery, including the broad topic of animal reproduction, which is far beyond the scope of this human-focused review. (frontiersin.org)
Where agency is the ability for a process to make responses that will maximize the likelihood of it achieving some goal (in biology, its usually reproduction). (physicsforums.com)
Advances in molecular biology are providing new tools with which to investigate poorly understood disorders of reproduction. (cdc.gov)
Clinical3
A thorough perinatal history, 3 birth defects have a high risk of death in the generations family pedigree and clinical ex- perinatal period and infancy [ 5 ]. (who.int)
Prospective assessment of the clinical benefit of a tailored cancer gene set built on a next-generation sequencing platform in patients with recurrent or metastatic head and neck cancer. (cdc.gov)
Rapid clinical mutational testing of KRAS , BRAF and EGFR : a prospective comparative analysis of the Idylla technique with high-throughput next-generation sequencing. (cdc.gov)
Search1
As we will see in Section 2 , researchers worked out the bottlenecks of face analysis by emphasizing on the model generation and their search methodologies. (hindawi.com)
Experimental1
Methods to use frozen ovarian tissue in reproduction are currently experimental. (upmc.com)
Species2
We describe the daily and weekly spawning kinetics of cultured broodstock analysing the family structure of single spawning events (45 for the two species) over the entire reproduction period. (europa.eu)
The rat is the preferred animal species for reproduction studies according to test guidelines. (europa.eu)
Abstract1
American painter, prominent among the first generation of Abstract Expressionists. (galeriedada.com)
This plot uses the EpiNow2 package ( https://cran.r-project.org/web/packages/EpiNow2/index.html ) to estimate the time-varying reproduction number on cases by date of report. (cdc.gov)
Color2
Blackmagic RAW uses Blackmagic generation 5 color science for reproducing extremely accurate skin tones and gorgeous, lifelike colors that rival those of cameras costing tens of thousands of dollars more! (blackmagicdesign.com)
That includes some current-generation OLED displays which provide unmatched color reproduction and contrast ratios. (popsci.com)
Methods2
Developing next-generation methods to treat the most complex cases of infertility (no eggs, no sperm). (upmc.com)
Methods to use frozen testicular tissue in reproduction are still in development. (upmc.com)
Seasonal1
For more than a half century the hormone melatonin has been associated with vertebrate reproduction, particularly in the context of seasonal breeding. (frontiersin.org)
Time4
We assumed that all cases with a history of travel to Canary Islands were imported and that all the others were locally transmitted, and we used a generation time distribution with mean 12.5 days. (cdc.gov)
The graph shows the effective reproduction number (Rt) estimation over time based on complete data (green) or partial data (orange). (cdc.gov)
The time-varying reproduction number is the average number of secondary cases infected by a single primary case in a large population. (cdc.gov)
We approximated the generation time using an estimate of the serial interval (rash onset to rash onset) with mean of 7.0 days (95% CrI 5.8 - 8.4) and standard deviation of 4.2 (95% CrI: 3.2 - 5.6) from 40 case pairs (primary-secondary) across 12 U.S. jurisdictions. (cdc.gov)
Effective3
CDC is using a model to estimate the effective reproduction number (Rt) for the mpox outbreak in the US. (cdc.gov)
The carefully designed curved back cover of this Philips docking speaker creates a highly effective acoustic structure for sound reproduction. (philips.com)
Employing a mathematical model, the effective reproduction number was estimated for each generation of cases. (who.int)
Replacement1
Replacement" refers to a minimum rate of reproduction necessary for generation to exactly replace itself, that is, enough children born to replace a group of 1,000 women and their partners. (cdc.gov)
Individuals1
The entanglement among different individuals allows us to clone the classical information and propagate the quantum coherences of the initial quantum living units to the successive generations," says Alvarez-Rodriguez and co. (technologyreview.com)
Life2
The resulting simulation is so complex that it can be done on a classical computer only for a small number of generations and this severely limits what can be learned about the nature of quantum life. (technologyreview.com)
Reindeer herding has been a way of life for Indigenous Peoples for generations. (nsidc.org)
Average1
On the average, 12 generations of houseflies can be produced in one year. (enchantedlearning.com)
Plant1
Pollination ecology: how do bees move across the landscape and fashion plant reproduction? (europa.eu)
Steps1
Biology's goals are often have something to do with reproduction or with steps leading to reproductive success. (physicsforums.com)