• fold
  • Using a hierarchical method, a clustering graph was created from those miRNAs with increased (red) or decreased (blue) fold of expression from 3 soleus muscles (left graph) and dorsal root ganglia (right graph) in the group of rats that sustained denervation for 6 months, entrapment for 6 months, or decompression for 3 months against those from the sham control group. (nih.gov)
  • The expression profiles were studied by Gene Expression module (Gx) using the Genome Studio software and statistical analysis was done to analyze fold expression between cases and controls. (arvojournals.org)
  • 2-fold change of expression, when non proliferative ROP subjects were included in the control group. (arvojournals.org)
  • 2-fold change) showed significant differential expression, indicating the involvement of inflammation mediated by chemokine and cytokine, endothelin and toll like receptor signaling pathways, respectively. (arvojournals.org)
  • analysis
  • Regarding the muscle-specific miRNAs, real-time RT-PCR analysis revealed an approximately 50% decrease in miR-1 and miR-133a expression levels at 3 and 6 months after entrapment, whereas miR-1 and miR-133a levels were unchanged and were decreased after decompression at 1 and 3 months. (nih.gov)