Gene encodes membrane glycoproteins. Medical search. Frequent questions

Seven virus-encoded proteins have been identified that are components of IEV, and five of them are present in CEV or EEV. (microbiologyresearch.org)
These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. (nih.gov)
Differentially expressed candidate genes for ageing previously identified in the human blood transcriptome up-regulated in PP cows were mainly associated with T-cell function ( CCR7 , CD27 , IL7R , CAMK4 , CD28 ), mitochondrial ribosomal proteins ( MRPS27 , MRPS9 , MRPS31 ), and DNA replication and repair ( WRN ). (biomedcentral.com)
Kidney Injury Molecule-1 (KIM-1, HAVCR1) is a class I integral membrane glycoprotein that belongs to the TIM family of proteins. (transcriptionfactor.org)
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. (transcriptionfactor.org)
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. (transcriptionfactor.org)
It encodes a transcription factor that regulates major histocompatibility complex (MHC) genes, which code for the cell surface proteins that present foreign substances to adaptive immune cells. (the-scientist.com)
Fibronectin proteins are found in the glomerular basement membrane of the mouse kidney. (bicellscientific.com)
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins - integrins. (bicellscientific.com)
Three of these RNP segments encode the virus' surface proteins, i.e., the HA, NA and M proteins. (cdc.gov)

This protein is one of the plasma membrane components of adherens junctions. (nih.gov)
the human version of the protein encoded by the MDR1 gene), a drug-transporter glycoprotein associated with the cell or plasma membrane (which encloses the cell's cytoplasm) with a wide variety of drug substrates. (thefutureofthings.com)
Further investigation demonstrated that electrical stimulation not only decreases levels of the MDR1 glycoprotein transporter, but also changes the localization of the MDR1 glycoprotein from close to the plasma membrane to the cytosol (the fluid portion of the cytoplasm). (thefutureofthings.com)
The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains. (modellab.cn)
P-glycoprotein (Pgp) is a plasma membrane protein encoded by mammalian multidrug resistance gene (MDRI). (wikidoc.org)
A primary role of plasma membrane P-glycoprotein (P-gp), encoded by multidrug resistance type I (MDR1), is to protect against naturally occurring xenotoxics. (elsevierpure.com)

This gene encodes a receptor for the OX-2 membrane glycoprotein. (antibodies-online.com)
Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. (antibodies-online.com)
The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. (microbiologystudents.com)
The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. (abeomics.com)
The protein encoded by this gene acts as a membrane receptor for both the human hepatitis A virus (HHAV) and TIMD4. (transcriptionfactor.org)
The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. (transcriptionfactor.org)
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. (transcriptionfactor.org)
The osteoclast vitronectin receptor is found in the cell membrane. (transcriptionfactor.org)
The Her-2/ neu proto-oncogene, also known as c-erbB-2, is a member of the type I growth factor receptor gene family and is located in the long arm of chromosome 17 (17q12-21.32) [ 1 ]. (biomedcentral.com)
Classed as a type I integral membrane glycoprotein, in its capacity as a receptor, LYVE1 can bind to soluble and immobilised HA. (prospecbio.com)
The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. (dimabio.com)
NPC1 encodes the receptor that Ebola virus binds to, but CIITA was more mysterious. (the-scientist.com)
Ebola computer virus glycoprotein (GP) is the only viral surface protein and is solely responsible for receptor binding and mediating fusion of viral and host membranes during viral entry [15,16]. (cell-signaling-pathways.com)
Rabbit anti Human ADRM1 antibody recognizes the proteasomal ubiquitin receptor ADRM1, also known as 110 kDa cell membrane glycoprotein, proteasome regulatory particle non-ATPase 13, rpn13 homolog or Adhesion-regulating molecule 1. (bio-rad-antibodies.com)
The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. (bio-rad-antibodies.com)

LYVE1 is a type I integral membrane glycoprotein. (wikipedia.org)
Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. (wikidoc.org)
Description: This gene encodes a type I integral membrane glycoprotein. (microbiologystudents.com)

IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. (utsouthwestern.edu)
The encoded protein is secreted and binds hydroxyapatite with high affinity. (transcriptionfactor.org)
TRAP AND KILL: Overexpressing the transcription factor CIITA in cultured human cells turns on a gene called CD74 , producing the protein p41, which binds to cathepsin proteases in the endosome (left). (the-scientist.com)
The p41 protein binds to proteases called cathepsins, preventing the enzymes from cleaving the Ebola glycoprotein, thus stopping the fusion of the virus with the endosome and the release of the viral genome into the cell, the team demonstrated. (the-scientist.com)
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA . (lookformedical.com)

The gene ICAM3 (intercellular adhesion molecule 3) encodes type I membrane glycoprotein that belongs to the immunoglobulin (ig) superfamily. (sigmaaldrich.com)
CD273 is a 42-kDa type I membrane glycoprotein encoded by the Pdcd1lg2 gene of the B7 family of the Ig superfamily. (bdbiosciences.com)
This gene encodes a member of the cadherin superfamily. (anticorps-enligne.fr)
Kia1 (CD82) has been shown to associate with CD4 and CD8, and delivers costimulatory signals for the TCR/CD3 pathway.This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. (kerafast.com)

Cell entry by measles virus: long hybrid receptors uncouple binding from membrane fusion. (1library.net)
Analysis of this HA gene shows that it is closely related to avian A(H5) viruses in HA clade 2.3.4.4b and lacked amino acid changes that improve recognition of mammalian receptors or fusion of the viral membrane with the host endosomal membranes. (cdc.gov)
A(H5) viruses in HA clade 2.3.4.4b and lacked amino acid changes that improve recognition of mammalian receptors or fusion of the viral membrane with the host endosomal membranes. (cdc.gov)
These hormones act on cells in virtually every body tissue by combining with nuclear receptors and altering expression of a wide range of gene products. (msdmanuals.com)

Based on the tumor purity and lung carcinoma gene matrix, we performed weighted gene coexpression network analysis (WGCNA), and the tumor purity-related module was identified. (hindawi.com)
Five coexpressed genes (CD4, CD53, EVI2B, PLEK, and SASH3) were identified as tumor purity coexpressed genes that negatively correlated with tumor purity. (hindawi.com)
Using GSEA analysis, we found that the antigen processing and presentation pathway were related to the five tumor coexpressed genes mentioned above. (hindawi.com)
In this study, we constructed a tumor purity coexpression network based on weighted gene coexpression network analysis (WGCNA) [ 8 ]. (hindawi.com)
In a study led by Luca Cucullo and Damir Janigro from the Cleveland Clinic Lerner College of Medicine in Ohio that was recently published by the open access journal, BioMed Central, tumor cells that overexpress the MDR1 gene product were shown to lose their resistance to anti-tumor drugs by electrical stimulation. (thefutureofthings.com)
The researchers concluded that treatment of the drug-resistant tumor cells with low frequency, low intensity AC stimulation in vitro drastically enhances chemotherapeutic efficacy of doxorubicin, a substrate for the MDR1 glycoprotein drug transporter. (thefutureofthings.com)
Decreased expression of this gene may be associated with tumor growth and metastasis. (anticorps-enligne.fr)
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. (transcriptionfactor.org)
The RECK gene is widely expressed in normal human tissues but is downregulated in tumor cell lines and oncogenically transformed fibroblasts. (korea.ac.kr)
RECK encodes a membrane-anchored glycoprotein that suppresses tumor invasion and angiogenesis by regulating matrix-metalloproteinases (MMP-2, MMP-9 and MT1-MMP). (korea.ac.kr)
Understanding of the transcriptional regulation of tumor/metastasis suppressor genes constitutes a potent approach to the molecular basis of malignant transformation. (korea.ac.kr)
Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. (kerafast.com)
Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS . (lookformedical.com)

Extracellular vaccinia virus formation and cell-to-cell virus transmission are prevented by deletion of the gene encoding the 37,000-Dalton outer envelope protein. (microbiologyresearch.org)
The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation. (transcriptionfactor.org)

Dissociation of progeny vaccinia virus from the cell membrane is regulated by a viral envelope glycoprotein: effect of a point mutation in the lectin homology domain of the A34R gene. (microbiologyresearch.org)
A mutation in the F2 gene leads to increased gene expression, i.e., excessive prothrombin production. (treegene.kz)
The primary defect in Dubin-Johnson syndrome is a mutation in an apical canalicular membrane protein responsible for the excretion of bilirubin and other nonbile salt organic anions. (medscape.com)
Affected individuals have a mutation in both copies of the ABCB11 gene. (medlineplus.gov)
Development of this condition requires a mutation in both copies of the ABCB11 gene. (medlineplus.gov)
In rare cases, an uncommon change (a mutation) in one copy of the ABCB11 gene is found in women with intrahepatic cholestasis of pregnancy. (medlineplus.gov)
A single mutation in this gene increases the risk of developing intrahepatic cholestasis of pregnancy. (medlineplus.gov)

Cells that overexpress the MDR1 gene are, hence, resistant to many drugs. (thefutureofthings.com)
This altered expression of the MDR1 glycoprotein is believed to have caused the loss of the cell's drug extrusion ability, which it mediates. (thefutureofthings.com)
Ochilova G.S., Musaeva D.M. The effect of polymorphism of the MDR1 gene on the effectiveness of treatment of chronic gastritis. (umsida.ac.id)

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. (nih.gov)
The herpes simplex virus type 1 (HSV-1) glycoprotein N (gN/UL49.5) is a type I transmembrane protein conserved throughout the herpesvirus family. (mdpi.com)
The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. (anticorps-enligne.fr)
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. (dimabio.com)
It functions as a transcriptional activator for the INTERFERON TYPE I genes. (lookformedical.com)
Mutations in the ABCB11 gene can cause benign recurrent intrahepatic cholestasis type 2 (BRIC2). (medlineplus.gov)
More than 100 mutations in the ABCB11 gene have been found to cause a severe form of liver disease called progressive familial intrahepatic cholestasis type 2 (PFIC2) that usually leads to liver failure. (medlineplus.gov)

Human ITGA2 genome location and ITGA2 gene details page in the UCSC Genome Browser . (wikidoc.org)
Transposons, mobile genetic elements found throughout the genome, can be added to cells to knock out genes they randomly insert into. (the-scientist.com)
It is important to notice that unlike all current spliced alignment methods that are meant for cDNA-to-genome alignments and can be used for CDS-to-gene alignments, SFA is the first method specifically designed for CDS-to-gene alignments. (biomedcentral.com)

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES . (lookformedical.com)

Era of Pseudovirions Three types of recombinant pseudoviruses (HIV-1/EBOV, HIV-1/H5N1, and HIV-1/LASV) had been found in this research, plus they all included the matching viral membrane glycoproteins (Gps navigation). (cell-signaling-pathways.com)

In the Ebola experiments, Lacy-Hulbert, Bruchez, and their colleagues had been using a genetic screen called transposon-mediated gene activation to search for natural antiviral mechanisms within cultured human bone cancer cells. (the-scientist.com)
After adding these transposons to flasks of human cells, Bruchez introduced viruses engineered to express an Ebola glycoprotein, killing most of the cells. (the-scientist.com)
When the cells are exposed to an Ebola-mimicking virus, the p41-bound cathepsins are unable to cleave off the virus's glycoprotein, stopping it from fusing with the membrane and thus trapping it inside the endosome. (the-scientist.com)
One isoform in particular, p41 , could keep CD74 knockout cells alive in the face of the virus with the Ebola glycoprotein. (the-scientist.com)
Open in a separate window Physique 1 Small molecule inhibitors targeting Ebola glycoprotein. (cell-signaling-pathways.com)

Alternative splicing of this gene results in multiple transcript variants. (antibodies-online.com)
Two transcript variants encoding different isoforms have been found for this gene. (nih.gov)
Alternative splicing results in multiple transcript variants encoding different isoforms. (utsouthwestern.edu)

Kim R. Drugs as P-glycoprotein substrates, inhibitors, and inducers. (umsida.ac.id)

The follicular cells surround a space (follicle) filled with colloid, which consists of thyroglobulin, a glycoprotein containing tyrosine within its matrix. (msdmanuals.com)
Tyrosine in contact with the membrane of the follicular cells is iodinated at 1 (monoiodotyrosine) or 2 (diiodotyrosine) sites and then coupled to produce the 2 forms of thyroid hormone. (msdmanuals.com)

Rational Laboratory Diagnostics of Antiphospholipid Antibodies: Anti-Cardiolipin, Anti-β2-Glycoprotein I, Anti-Prothrombin and Anti-Annexin V Antibodies. (ncbcs.org)
A attainable co-appearance of anticardiolipin (aCL), anti-β2-glycoprotein I (anti-β2-GPI), anti-prothrombin (aPT) and anti-annexin V (aANXV) antibodies of IgG, IgM and IgA class have been studied in 58 sufferers with SLE alone and 32 sufferers APS within the view of rational laboratory diagnostics. (ncbcs.org)

Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). (edu.au)

Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. (edu.au)

Ochilov A.K., Ochilova G.S. Clinical significance of polymorphisms of the CYP2C19 gene // University science: a look into the future. (umsida.ac.id)
Ochilov A.K., Ochilova G.S. Clinical significance of polymorphisms of the CYP2C19 gene // Collection of scientific papers based on the materials of the International Scientific Conference "University science: a look into the future" dedicated to the 85th anniversary of Kursk State Medical University. (umsida.ac.id)
Recent advances have been made in the of host factors, polymorphisms, and candidate genes associated characterization of the immune response to low-molecular- with occupational asthma may improve our understanding of weight agents. (cdc.gov)

Sequence analysis, expression, and deletion of a vaccinia virus gene encoding a homolog of profilin, a eukaryotic actin-binding protein. (microbiologyresearch.org)
3 cows with MP 2-3 as background using DESeq2 followed by weighted gene co-expression network analysis (WGCNA). (biomedcentral.com)
Understanding the expression of P-glycoprotein is essential for comprehending drug pharmacokinetics and optimizing pharmacotherapy outcomes. (umsida.ac.id)
In this study, our goal was to investigate the influence of P-glycoprotein expression on drug permeability and its implications for therapeutic effectiveness. (umsida.ac.id)
This research emphasizes the necessity of considering P-glycoprotein expression when designing drug delivery strategies, enabling targeted therapies, and maximizing therapeutic efficacy. (umsida.ac.id)
Influence of P-glycoprotein expression on pharmacotherapy outcomes. (umsida.ac.id)
We anticipate that this broadly applicable production method will advance glycoengineering efforts by enabling preparative expression of membrane-embedded OSTs from all kingdoms of life. (biorxiv.org)
The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle. (transcriptionfactor.org)
In order to uncover the mechanisms of control of RECK gene expression, the RECK promoter has been cloned and characterized. (korea.ac.kr)
A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression . (lookformedical.com)

Ochilova G. S. Characterization of glycoprotein-P as a drug transporter protein // New day in medicine. (umsida.ac.id)

In a cell where CD74 is not overexpressed (right), cathepsins cleave the virus's glycoproteins, enabling it to fuse with the side of the endosome and release its genetic material into the cytosol. (the-scientist.com)

OBJECTIVE: The ABCB1 gene encodes P-glycoprotein (P-gp), a cellular membrane pump. (edu.au)
P-glycoprotein: Key regulator of drug permeability and cellular absorption. (umsida.ac.id)
Specifically, by using lipid nanodiscs as cellular membrane mimics, we obtained yields of up to 440 µg/mL for the single-subunit OST enzyme, 'Protein glycosylation B' (PglB) from Campylobacter jejuni , as well as for three additional PglB homologs from Campylobacter coli, Campylobacter lari , and Desulfovibrio gigas . (biorxiv.org)

Ochilov A.K., Musayeva D.M. "Treatment of chronic gastritis depending on allelic variants of the CYP2C19 gene" "Topical issues of medical science in the XXI century" Tashkent, 04/25/2019. (umsida.ac.id)

In humans it is encoded by the LYVE1 gene. (wikipedia.org)

Le pourcentage de CD44 dans les lymphocytes T périphériques était significativement plus élevé chez les patients que chez les témoins, comme détecté par la cytométrie en flux. (who.int)

In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. (edu.au)

The top three clusters from modules more highly expressed in the PP cows all involved regulation of gene transcription, particularly zinc fingers. (biomedcentral.com)
This gene is a member of the caudal-related homeobox transcription factor gene family. (transcriptionfactor.org)
Understanding of the mechanisms which control RECK gene transcription may lead to the development of new strategies for cancer prevention and treatment. (korea.ac.kr)

To find out what it was, the team knocked down each of the genes that CIITA regulates, and found one, CD74 (which encodes part of the MHC), that was key to cell survival. (the-scientist.com)

The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. (transcriptionfactor.org)

The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. (utsouthwestern.edu)
In 20-30% of breast carcinomas, Her-2/ neu status is altered, and this is manifested either as amplification of the gene or overexpression of the protein product [ 3 ]. (biomedcentral.com)

In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. (edu.au)

Integrin alpha-2 or CD49b (cluster of differentiation 49b) is a protein which in humans is encoded by the CD49b gene . (wikidoc.org)
Genes and pathways associated with lactation number in cows were identified for the first time to date, and we found that many were comparable to those known to be associated with ageing in humans and model organisms. (biomedcentral.com)
The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. (edu.au)

Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. (anticorps-enligne.fr)

The neuraminidase (NA) gene encodes the other surface protein of the virus. (cdc.gov)

This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. (abeomics.com)
ADRM1 gene encodes a member of the adhesion regulating molecule 1 protein family. (bio-rad-antibodies.com)

Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. (antibodies-online.com)

IEV is formed by wrapping of IMV with intracellular membranes, and is an intermediate between IMV and CEV/EEV that enables efficient virus dissemination to the cell surface on microtubules. (microbiologyresearch.org)

The team had integrated a promoter sequence into the transposons so that, in addition to knocking out some genes, they would turn other genes on. (the-scientist.com)
The splicing structure of a sequence refers to the exon extremity information in a CDS or the exon-intron extremity information in a gene sequence. (biomedcentral.com)
To address this issue, we introduce a new spliced alignment problem and a method called SplicedFamAlign (SFA) for computing the alignment of a spliced CDS against a gene sequence while accounting for the splicing structures of the input sequences, and then the inference of transcript splicing orthology groups in a gene family based on spliced alignments. (biomedcentral.com)
The isolate was serologically identified by Dot-ELISA and further characterized by RT-PCR then genotyped using S1 gene sequence analysis. (biomedcentral.com)

This gene belongs to the angiopoietin family of growth factors. (transcriptionfactor.org)

We selected 17 patients clinically and his- is encoded by a single gene located on the tologically proven to be suffering from PV short arm of chromosome 11 [ 6 ]. (who.int)
Several single gene disorders share clinical and radiologic characteristics with multiple sclerosis and have the potential to be overlooked in the differential diagnostic evaluation of both adult and paediatric patients with multiple sclerosis. (medscape.com)
Recognition of a single-gene disorder as causal for a patient's 'multiple sclerosis-like' phenotype is critically important for accurate direction of patient management, and evokes broader genetic counselling implications for affected families. (medscape.com)
Here we review single gene disorders that have the potential to mimic multiple sclerosis, provide an overview of clinical and investigational characteristics of each disorder, and present guidelines for when clinicians should suspect an underlying heritable disorder that requires diagnostic confirmation in a patient with a definite or probable diagnosis of multiple sclerosis. (medscape.com)

The hemagglutinin (HA) gene codes for one of the two surface glycoproteins and is central to species specificity because it is responsible for virus attachment and fusion with host cells. (cdc.gov)

The encoded protein is extensively glycosylated and contains five Ig-like domains that share high homology with corresponding domains in ICAM-1 and ICAM-2. (sigmaaldrich.com)
Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. (nih.gov)

Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. (edu.au)

Combinations of face envelope with T-shaped spikes measuring 7-10 key words such as Lassa fever and West Africa were nm and built with glycoprotein. (folkhalsomyndigheten.se)

The plasmids formulated with GP-encoding genes utilized had been: influenza. (cell-signaling-pathways.com)
This illustration depicted a 3D computer-generated rendering of a half-sliced influenza (flu) virus with a grey surface membrane, set against a white background. (cdc.gov)
Every influenza virus has eight RNP segments that correspond to the virus' eight total gene segments. (cdc.gov)

[ 5 ] Although enormous progress has recently been made in defining and characterizing the molecular biology, immunology, and antiviral therapeutic targets for CMV, considerable work remains in devising strategies for prevention of CMV infection and in understanding the role of specific viral genes in pathogenesis. (medscape.com)

3 cows were pooled, and the gene lists subjected to David functional annotation cluster analysis. (biomedcentral.com)

Another cluster included genes encoding enzymes in the mitochondrial beta-oxidation pathway. (biomedcentral.com)

This protein plays a crucial role in actively facilitating the absorption of drugs across cell membranes. (umsida.ac.id)

The results unveiled the pivotal role of P-glycoprotein in modulating drug permeability and highlighted its significance in determining pharmacotherapy outcomes. (umsida.ac.id)

The inference of splicing orthology relationships between gene transcripts is a basic step for the prediction of transcripts and the annotation of gene structures in genomes. (biomedcentral.com)
It can also be used for gene structure annotation and alternative splicing analyses. (biomedcentral.com)

The gene is mapped to human chromosome 19p13.2. (sigmaaldrich.com)
Fibronectin is encoded by the FN1 gene in human. (bicellscientific.com)

Anatomy46

Organisms17

Diseases2

Chemicals and Drugs115

Analytical, Diagnostic and Therapeutic Techniques and Equipment29

Phenomena and Processes47

Disciplines and Occupations2

Technology, Industry, Agriculture6

Information Science4

Health Care1

Proteins10

Plasma membrane6

Receptor15

Integral3

Binds5

Superfamily4

Receptors4

Tumor13

Extracellular2

Mutation7

MDR13

Type7

Genome3

Mammalian1

Viral membrane1

Ebola5

Transcript variants3

Inhibitors1

Tyrosine2

Antibodies2

Transmembrane1

Alpha subunit1

Polymorphisms3

Expression10

Drug transporter1

Cytosol1

Cellular3

Variants1

LYVE11

CD441

Subunits1

Transcription3

Regulates1

Regulator1

Protein product2

Chromosome 171

Humans3

Morphogenesis1

Surface protein1

Molecule2

Myeloid1

Cell surface1

Sequence4

Belongs1

Single gene4

Specificity1

Domains2

Immune1

Envelope1

Influenza3

Infection1

Functional1

Pathway1

Drugs1

Outcomes1

Annotation2

Human2