• electrophysiologic
  • In contrast, ectopic activation of Wnt signaling was sufficient to induce formation of ectopic AV junction-like tissue as assessed by morphology, gene expression, and electrophysiologic criteria. (ahajournals.org)
  • The ECG may show any of the following: Inappropriate sinus bradycardia Sinus arrest Sinoatrial block Tachy-Brady Syndrome Atrial fibrillation with slow ventricular response A prolonged asystolic period after a period of tachycardias Atrial flutter Ectopic atrial tachycardia Sinus node reentrant tachycardia Wolff-Parkinson-White syndrome Electrophysiologic tests are no longer used for diagnostic purposes because of their low specificity and sensitivity. (wikipedia.org)
  • protein
  • It is of note that only a small proportion of the transcribed RNAs are translated into protein with the remainder performing a host of functions, affecting those sequences (genes) that encode for protein. (onlinejacc.org)
  • While the function of the LAMP2 gene is not well understood, it is known that LAMP2 protein is primarily located in small structures within cells called lysosomes. (wikipedia.org)
  • patients
  • Patients with AF, WPW syndrome, and rapid ventricular response who are hemodynamically compromised should receive prompt direct-current cardioversion. (medscape.com)
  • Administration of intravenous amiodarone, adenosine, digoxin (oral or intravenous), or nondihydropyridine calcium channel antagonists (oral or intravenous) in patients with WPW syndrome who have preexcited AF is potentially harmful because these drugs accelerate the ventricular rate. (medscape.com)
  • Symptomatic Patients with WPW syndrome are treated by transvenous catheter ablation of the AP. (ahajournals.org)
  • An individual displaying MERRFs syndrome will manifest not only a single symptom, but regularly patients display more than one affected body part at a time. (wikipedia.org)
  • It has been observed that patients with MERRF syndrome will primarily display Myoclonus as a first symptom, along with it they can also manifest seizures, cerebellar ataxia and myopathy. (wikipedia.org)
  • potassium
  • Ajmaline was first discovered to lengthen the refractory period of the heart by blocking sodium ion channels, but it has also been noted that it is also able to interfere with the hERG (human Ether-a-go-go-Related Gene) potassium ion channel. (wikipedia.org)
  • clinical
  • Because of the size of the family (27 gene carriers), the clinical consequences associated with the altered splicing of exon 25 could be reliably assessed as incomplete penetrance, late onset of disease, and low cardiac mortality. (ahajournals.org)
  • disorders
  • Rapid DNA sequencing is being embraced for single gene disorders, particularly for sporadic cases and those from small families. (onlinejacc.org)
  • A number of inherited disorders may also increase the risk including long QT syndrome. (wikipedia.org)
  • diagnostic
  • The disease phenotype in this family was characterized in detail: only 10 of 27 gene carriers fulfilled diagnostic criteria. (ahajournals.org)
  • Diseases
  • Coronary artery disease, high blood pressure, and aortic and mitral valve diseases may be associated with sick sinus syndrome, although this association may only be incidental. (wikipedia.org)