• This bacterium is grown at 37 °C under aerobic or anaerobic conditions, thus C. pseudotuberculosis is a facultative anaerobe. (wikipedia.org)
  • Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that belongs to the so-called CMN ( Corynebacterium-Mycobacterium-Nocardia ) group, a distinct subgroup of the Actinobacteria that also includes other highly important bacterial pathogens, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis . (biomedcentral.com)
  • Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. (wikipedia.org)
  • citation needed] Shortly after, it was sampled from abscesses in a sheep by Hugo von Preisz [hu], and the bacterium was named the "Preisz-Nocard" bacillus until further work by German microbiologists in the mid-1900s, when it was recategorized into the Corynebacterium genus. (wikipedia.org)
  • C. pseudotuberculosis is a Gram-positive bacterium that can be either coccoid or filamentous rods, which can be organized into palisades. (wikipedia.org)
  • Hence, we sought to implement a combined approach for characterizing the entire exoproteome of the pathogenic bacterium Corynebacterium pseudotuberculosis , the etiological agent of caseous lymphadenitis (CLA) in sheep and goats. (biomedcentral.com)
  • Comparative analyses of the exoproteomes of two C. pseudotuberculosis strains, in addition to comparison with other experimentally determined corynebacterial exoproteomes, were helpful to gain novel insights into the contribution of the exported proteins in the virulence of this bacterium. (biomedcentral.com)
  • Human granulocytic anaplasmosis ( HGA ) is a tick-borne , infectious disease caused by Anaplasma phagocytophilum , an obligate intracellular bacterium that is typically transmitted to humans by ticks of the Ixodes ricinus species complex, including Ixodes scapularis and Ixodes pacificus in North America. (mdwiki.org)
  • In small ruminants, C. pseudotuberculosis causes a disease called caseous lymphadenitis characterized by pyogranulomatous abscess formation. (wikipedia.org)
  • citation needed] Distribution of C. pseudotuberculosis is mostly traced by examining prevalence of caseous lymphadenitis, the bacterium's main pathological disease. (wikipedia.org)
  • Respiratory diphtheria is a serious infection caused by toxigenic Corynebacterium diphtheriae, and disease transmission mainly occurs through respiratory droplets. (cdc.gov)
  • Here we utilized whole-genome sequencing (WGS) to characterize recovered isolates of C. diphtheriae and two co-circulating non-diphtheritic Corynebacterium (NDC) species - C. pseudodiphtheriticum and C. propinquum. (cdc.gov)
  • 44 proteins were commonly identified in two different strains, isolated from distinct hosts, then composing a core C. pseudotuberculosis exoproteome. (biomedcentral.com)
  • Also, multidrug resistance to ≥ 3 classes of antimicrobials was found in 23.5% (8/34) strains. (bvsalud.org)
  • Moreover, evidence could be found for probable non-classical export of most of the remaining proteins. (biomedcentral.com)
  • In fact, one might expect that the majority of the virulence determinants of C. pseudotuberculosis would be present in the exoproteome, i.e . the entire set of bacterial proteins found in the extracellular milieu [ 7 ]. (biomedcentral.com)
  • The bacteria infect white blood cells called neutrophils , causing changes in gene expression that prolong the life of these otherwise short-lived cells. (mdwiki.org)
  • Blood and the pleural fluid (purulent aspect) samples were subjected to qPCR (16S rRNA and dsb genes) and sequencing, which identified Ehrlichia canis and Anaplasma platys coinfection. (bvsalud.org)
  • A disease known as ulcerative lymphagenitis can also result from infection with C. pseudotuberculosis in the distal limbs of horses. (wikipedia.org)
  • citation needed] C. pseudotuberculosis also causes disease in horses, and should be considered prevalent in areas where cases of "pigeon fever" and "ulcerative lymphadenitis" have been recorded. (wikipedia.org)
  • Specifically, C. pseudotuberculosis is intrinsically resistant to streptomycin, with varying resistance to penicillin and neomycin depending on the strain. (wikipedia.org)
  • We propose 2 diagnostic strategies that use partial sequencing of rpoB and secA1 genes and a multilocus sequence typing protocol. (cdc.gov)
  • An optimized protocol of three-phase partitioning (TPP) was used to obtain the C. pseudotuberculosis exoproteins, and a newly introduced method of data-independent MS acquisition (LC-MS E ) was employed for protein identification and label-free quantification. (biomedcentral.com)
  • In small ruminants, C. pseudotuberculosis causes a disease called caseous lymphadenitis characterized by pyogranulomatous abscess formation. (wikipedia.org)
  • citation needed] Distribution of C. pseudotuberculosis is mostly traced by examining prevalence of caseous lymphadenitis, the bacterium's main pathological disease. (wikipedia.org)
  • citation needed] C. pseudotuberculosis also causes disease in horses, and should be considered prevalent in areas where cases of "pigeon fever" and "ulcerative lymphadenitis" have been recorded. (wikipedia.org)
  • Streptococcus pneumoniae and Corynebacterium kutscheri are potent respiratory pathogens in the rat but seldom in the absence of some combination involving M. pulmonis, Sendai virus, and/or CAR bacillus. (nih.gov)
  • A disease known as ulcerative lymphagenitis can also result from infection with C. pseudotuberculosis in the distal limbs of horses. (wikipedia.org)
  • Infection of domesticated sheep and goats has been found across the globe. (wikipedia.org)
  • Respiratory diphtheria is a serious infection caused by toxigenic Corynebacterium diphtheriae, and disease transmission mainly occurs through respiratory droplets. (cdc.gov)
  • The only significant finding was more severe thrombocytopenia among patients with P. ovale wallikeri infection than among those with P. ovale curtisi infection (p = 0.031). (cdc.gov)
  • Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. (wikipedia.org)
  • As vector patterns change with warming temperatures, C. pseudotuberculosis in horses is re-emerging in the United States. (wikipedia.org)
  • We conducted a multicenter, retrospective, comparative study in Spain of 21 patients who had imported P. ovale curtisi infections and 14 who had imported P. ovale wallikeri infections confirmed by PCR and gene sequencing during June 2005-December 2011. (cdc.gov)
  • citation needed] Although few recent studies have been conducted into its prevalence, data from slaughterhouses in Australia in the late 1980s suggested that C. pseudotuberculosis was affecting 50-60% of sheep. (wikipedia.org)
  • We did not find changes in either packed cell volume, which is an internal control for volemic changes, or thrombocytes (data not shown). (mdmsignaling.com)
  • In contrast, we found a significant effect of supplementation on basophils and lymphocytes in response to exercise. (mdmsignaling.com)