• A, C, G, and T are the four types of bases found in a DNA molecule: adenine (A), cytosine (C), guanine (G), and thymine (T). A DNA molecule consists of two strands wound around each other, with each strand held together by bonds between the bases. (discovery.org)
  • The expansion of the cytosine-adenine-guanine (CAG) trinucleotide in the HTT gene leads to the production of atypical protein. (medicalnewstoday.com)
  • I wasn't aware of Chargaff's rules when he said them, but the effect on me was quite electric because I realized immediately that if you had this sort of scheme that John Griffith was proposing, of adenine being paired with thymine, and guanine being paired with cytosine, then you should get Chargaff's rules. (todayinsci.com)
  • It has been found experimentally that the ratio of the amounts of adenine to thymine, and the ratio of guanine to cytosine, are always very close to unity for deoxyribose nucleic acid. (todayinsci.com)
  • Of the nucleosides from deoxyribonucleic acids, all that was known with any certainty [in the 1940s] was that they were 2-deoxy--D-ribosides of the bases adenine, guanine, thymine and cytosine and it was assumed that they were structurally analogous to the ribonucleosides. (todayinsci.com)
  • Everyone carries the gene, but only those who have a segment that repeats three bases of genetic code cytosine, adenine and guanine (CAG) many times will get it. (reason.com)
  • Huntington disease (HD) is caused by an expansion of cytosine-adenine-guanine (CAG) trinucleotide repeats within the HTT gene. (arupconsult.com)
  • Individuals with intermediate alleles (27-35 cytosine-adenine-guanine [CAG] repeats) typically do not have symptoms of Huntington disease (HD). (arupconsult.com)
  • Polymerase chain reaction (PCR) testing and size analysis for an expanded number of cytosine-adenine-guanine (CAG) trinucleotide repeats in the HTT gene may be performed for both symptomatic individuals and asymptomatic individuals with a family history of HD. (arupconsult.com)
  • Adding X and Y The alphabet of life has four letters: A for adenine, C for cytosine, G for guanine, and T for thymine. (nxtbook.com)
  • In the steps, adenine is paired with thymine and guanine is paired with cytosine. (msdmanuals.com)
  • Structural changes and neuropathology in the hypothalamus have been suggested to contribute to the non-motor manifestations of Huntington's disease (HD), a neurodegenerative disorder caused by an expanded cytosine-adenine-guanine (CAG) repeat in the huntingtin (HTT) gene. (lu.se)
  • Lastly, RNA has a uracil nitrogen base instead of thymine allowing the base-pair complementary rule: Adenine binds to Uracil, and Cytosine binds to Guanine. (cdc.gov)
  • This gene provides instructions for making APRT, an enzyme that helps to convert a DNA building block (nucleotide) called adenine to a molecule called adenosine monophosphate (AMP). (medlineplus.gov)
  • This de novo assembly of a red clover transcriptome from leaf material of droughted and non-droughted plants provides a rich source for gene identification, single nucleotide polymorphisms (SNP) and short sequence repeats (SSR). (biomedcentral.com)
  • AlkB homolog1 (ALKBH1) is shown to demethylate DNA adenine methylation (6mA) preferentially from single-stranded or unpaired DNA , while its demethylase activity and function in the chromatin context are unclear. (bvsalud.org)
  • However, in the context of mixed tissues , rather than on individual loci, the ALKBH1 mutation or overexpression mainly affects the expression of genes with a specific combination of chromatin modifications in the body region marked with H3K4me3 and H3K27me3 but depleted of DNA CG methylation . (bvsalud.org)
  • Epigenetic analysis revealed a specific N 6 -methyl adenine (m 6 A) methylating pattern including methylation of alginate, flagellar and quorum sensing associated genes. (frontiersin.org)
  • The study focused on DNA adenine methylation, a biochemical reaction which attaches a chemical, called a methyl group, to an adenine, one of the four building block molecules used to construct lengthy DNA strands and encode genes. (phys.org)
  • For instance, it is known that adenine methylation plays a critical role in how some bacteria defend themselves against viruses. (phys.org)
  • For decades, scientists thought that adenine methylation strictly happened in bacteria whereas human and other non- bacterial cells relied on the methylation of a different building block-cytosine-to regulate genes. (phys.org)
  • Scientists spotted high levels of adenine methylation in plant, fly, mouse, and human cells, suggesting a wider role for the reaction throughout evolution. (phys.org)
  • Some used techniques that can precisely measure adenine methylation levels from any cell type but do not have the capacity to identify which cell each piece of DNA came from, while others relied on methods that can spot methylation in different cell types but may overestimate reaction levels. (phys.org)
  • The method also appeared to be effective at quantifying adenine methylation in complex organisms. (phys.org)
  • β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. (sigmaaldrich.com)
  • Adenine also forms as a component of nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), which are involved in metabolism. (hindawi.com)
  • NAD (Nicotinamide adenine dinucleotide) and aging - does differential expression of KYNU and KMO genes reduce NAD levels. (blogspot.com)
  • Nicotinamide adenine dinucleotide (NAD) is a chemical found in cells which is at the centre of many metabolic processes. (blogspot.com)
  • NAD9/NAD7 (mitochondrial nicotinamide adenine dinucleotide dehydrogenase gene)-A new "Holy Grail" phylogenetic and DNA-barcoding marker for Arcellinida (Amoebozoa)? (unine.ch)
  • Nicotinamide adenine dinucleotide prevents neuroaxonal degeneration induced by manganese in cochlear organotypic cultures. (cdc.gov)
  • Mutation screening was carried out in the candidate gene by bi-directional sequencing of amplified products. (nih.gov)
  • Subsequent molecular analyses have indicated mutations ( mut genes) result in an increased mutation fre- that the W and Beijing isolates constitute a single group of quency and better adaptability of the bacterium to stressful strains designated as the W-Beijing genotype (Figure 1). (cdc.gov)
  • Dominant diseases can be caused by only one copy of a gene with a DNA mutation. (cdc.gov)
  • For recessive diseases, both copies of a gene must have the DNA mutation for a person to have one of these diseases. (cdc.gov)
  • Overall, 21 of 48 samples (44%) had a mutation in at least one of these three genes. (genengnews.com)
  • A mutation of the noggin ( NOG ) gene in a fibrodysplasia ossificans progressiva family has been described. (medscape.com)
  • [ 9 ] The FOP gene in the 17q21-22 region had been observed with several mutations described in the NOG gene (located in 17q22) in 4 fibrodysplasia ossificans progressiva patients, including the G91C mutation, which was transmitted dominantly in a Spanish fibrodysplasia ossificans progressiva family. (medscape.com)
  • A novel mutation in the activin A type 1 receptor gene was described in one patient. (medscape.com)
  • [ 13 ] . A patient from Japan with an ACVR1 gene mutation had normal development until age 17 years and a mild clinical course. (medscape.com)
  • Some traits are caused by mutated genes that are inherited or that are the result of a new gene mutation. (msdmanuals.com)
  • A novel mutation of the CYBB gene resulting in severe form of X-linked chronic granulomatous disease. (lu.se)
  • A splice-supporting intronic mutation in the last bp position of a cryptic exon within intron 6 of the CYBB gene induces its incorporation into the mRNA causing chronic granulomatous disease (CGD). (lu.se)
  • Molecular characterization of a novel splice site mutation within the CYBB gene leading to X-linked chronic granulomatous disease. (lu.se)
  • Analyzing 5′-upstream non-protein-encoding regions of the human mitochondrial function-associated genes, we speculate that mitochondrial functions could be recovered or improved at a transcriptional level. (intechopen.com)
  • This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. (thermofisher.com)
  • The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. (thermofisher.com)
  • Mutations in the APRT gene cause APRT deficiency. (medlineplus.gov)
  • APRT gene mutations lead to the production of an abnormal APRT enzyme with reduced function or prevent the production of any enzyme. (medlineplus.gov)
  • which means both copies of the gene in each cell have mutations. (medlineplus.gov)
  • The aim of this study was to characterise individuals fulfilling the current WHO criteria for SPS for germline mutations in these polyposis-associated genes. (nih.gov)
  • Individuals with SPS were tested for coding mutations and large deletions in the PTEN, SMAD4, and BMPR1A genes, for the MUTYH variants in exons 7 (Y179C) and 13 (G396D), and for the duplication upstream of GREM1. (nih.gov)
  • We found no variants that were likely to be deleterious germline mutations in the SPS cases in the PTEN, SMAD4, and BMPR1A genes. (nih.gov)
  • DNA mutations in a gene can change what protein is made. (cdc.gov)
  • Eighteen genes were statistically significantly mutated, including RIT1 activating mutations and newly described loss-of-function MGA mutations which are mutually exclusive with focal MYC amplification. (nature.com)
  • Independent researchers have identified mutations in the histone H3.3-coding gene H3F3A in a large proportion of pediatric cases of gliobastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), an aggressive brainstem astrocytic tumor that occurs almost exclusively in children. (genengnews.com)
  • Researchers for the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project simultaneously reported data from exon sequencing studies demonstrating that 78% of DIPGs and 22% of nonbrainstem pediatric glioblastomas (non-BS-PGs) harbor somatic mutations in H3F3A or in the related gene HIST1H3B, which encodes H3.1. (genengnews.com)
  • Their published paper is titled "Driver mutations in histone H3.3 and chromatin remodeling genes in pediatric glioblastoma. (genengnews.com)
  • Because the three genes weren't sequenced as part of the 600-gene The Cancer Genome Atlas (TCGA) Glioblastoma project, and mutations in H3F3A, ATRX, or DAXX weren't identified in another adult GBM sequencing study, the researchers wanted to see whether H3F3A mutations were indeed specific to GBM and/or pediatric cases. (genengnews.com)
  • Mutational analysis revealed point-mutations in the SOD1 gene to cosegregate with the disease in these pedigrees. (bmj.com)
  • Nonsense mutations of the CYBB gene in two Thai families with X-linked chronic granulomatous disease. (lu.se)
  • Characterization of 17 new cases of X-linked chronic granulomatous disease with seven novel mutations in the CYBB gene. (lu.se)
  • Characterization of six novel mutations in the CYBB gene leading to different sub-types of X-linked chronic granulomatous disease. (lu.se)
  • Adenine forms several biological compounds involved in a variety of cellular physiological processes such as adenosine triphosphate (ATP) in cellular respiration and deoxyribonucleic acid (DNA) in protein synthesis. (hindawi.com)
  • Your genome is another word for all of your genes, and your genes are made up of deoxyribonucleic acid or DNA. (acs.org)
  • Genes are segments of deoxyribonucleic acid (DNA) that contain the code for a specific protein that functions in one or more types of cells in the body or the code for functional ribonucleic acid (RNA) molecules. (msdmanuals.com)
  • Genes consist of deoxyribonucleic acid (DNA). (msdmanuals.com)
  • Haplotype analysis placed the cataract locus to a 5.0 cM region between D19S902 and D19S867, in close proximity to the L-ferritin light chain gene (FTL) on chromosome 19q13.3. (nih.gov)
  • reverse primer: ACCTGTTTCTGGAGCTCC) using edn1 gene reference sequence (locus NG_016196 on chromosome 6) available at NCBI [ 17 ]. (biomedcentral.com)
  • A chromosome contains a single, long piece of DNA with many different genes. (cdc.gov)
  • Linkage analysis in 18 familial ALS pedigrees associated the gene encoding Cu/Zn superoxide dismutase ( SOD1 ) on chromosome 21 to the syndrome. (bmj.com)
  • A chromosome contains hundreds to thousands of genes. (msdmanuals.com)
  • A chromosome contains many genes. (msdmanuals.com)
  • The CCR4-NOT complex regulates gene expression by processing, controlling quality, and marking mRNAs for destruction by shortening their poly(A) tails -- chains of adenine nucleotides at the end of mRNA molecules. (sciencedaily.com)
  • Gibco-BRL) and 100 μ g/mL penicillin/streptomycin at 37°C. For treatment with adenine (Sigma-Aldrich, St. Louis, MO, USA), cells were initially seeded in 6-well culture plates at a density of 1 × 10 5 cells/mL in a total volume of 2 mL and cultured overnight to reach approximately 80% confluence. (hindawi.com)
  • If one parent has a disease, each child has a 50% chance of inheriting the mutated gene. (cdc.gov)
  • When someone with Huntington's disease has children, each child has a 1 in 2 chance of inheriting the mutated gene and developing the disease. (medicalnewstoday.com)
  • Comparison of gene expression levels between pools and treatments identified candidate genes for further analysis of the genetic basis of drought tolerance in red clover. (biomedcentral.com)
  • Huntington's disease is genetic , involving the Huntingtin (HTT) gene. (medicalnewstoday.com)
  • Genetic researchers are already investigating which sets of genes, called haplotypes, combine to increase a person's risk of various diseases including cardiovascular disease . (reason.com)
  • The genetic cause of fibrodysplasia ossificans progressiva lies within the ACVR1 gene, which encodes a type I BMP transmembrane receptor. (medscape.com)
  • The genotype (or genome) is a person's unique combination of genes or genetic makeup. (msdmanuals.com)
  • Chromosomes are structures within cells that contain a person's genes. (msdmanuals.com)
  • Genes are contained in chromosomes, which are in the cell nucleus. (msdmanuals.com)
  • Protein synthesis is controlled by genes, which are contained on chromosomes. (msdmanuals.com)
  • It is of interest to explore the inhibitory effect of adenine on the growth of colorectal cancer cells and to determine the underlying mechanism. (hindawi.com)
  • We explored the possible mechanisms underlying the anticancer activity of adenine in colorectal cancer cells. (hindawi.com)
  • The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. (medlineplus.gov)
  • If both parents have one copy of the mutated gene, each child has a 25% chance of having the disease, even though neither parent has it. (cdc.gov)
  • qPCR was carried out to determine the changes in mRNA expression of genes of interest. (hindawi.com)
  • Specifically we evaluate the effect of increased dietary protein intake and caloric restricted diets on gene expression in skeletal muscle, particularly focusing on biosynthesis, degradation and the expression of genes in the ubiquitin-proteosome (UPP) and mTOR signaling pathways, including MuRF-1, MAFbx/atrogin-1, mTORC1, and S6K1. (biomedcentral.com)
  • So your genes are just sequences of A's T's C's and G's and they code for RNA which then codes for different proteins. (acs.org)
  • Sequivity is a custom swine vaccine platform … Sequivity only targets swine pathogen gene sequences of interest. (newstarget.com)
  • This can "epigenetically" activate or silence genes without actually altering DNA sequences. (phys.org)
  • The global distribution and success of M. tuberculosis iso- missense alterations in three putative mut genes, including lates of the W-Beijing genotype have led to the hypothesis two of the mutT type (Rv3908 and mutT 2) and ogt . (cdc.gov)
  • Whether and how a gene is expressed is determined by a complex interaction of multiple factors including genotype, gene expression, environmental factors (including illnesses and diet), and other factors, some of which are unknown. (msdmanuals.com)
  • Gene expression refers to the process of making proteins using the instructions from genes. (cdc.gov)
  • Since the early 2000s, when PCD was confirmed, research has focused mainly on finding genes and proteins that trigger it. (sciencedaily.com)
  • Then they characterized the three TPC proteins: MpTPC1 from the Type 1 TPC gene and MpTPC2 and MpTPC3 from the Type 2 TPC gene. (sciencedaily.com)
  • More than half of all human genes are alternatively spliced, so it is expected that alternative pre- mRNA splicing will be responsible for the identification of more than 90 percent of all human proteins. (genomicglossaries.com)
  • Genes vary in size, depending on the sizes of the proteins or RNA for which they code. (msdmanuals.com)
  • Adenine phosphoribosyltransferase (APRT) deficiency is an inherited condition that affects the kidneys and urinary tract. (medlineplus.gov)
  • Nicotinic acid adenine dinucleotide phosphate, (NAADP), is a Ca2+-mobilizing second messenger synthesised in response to extracellular stimuli. (wikipedia.org)
  • Molecules such as phosphatidylinositol-3,5-bisphosphate and nicotinic acid adenine dinucleotide phosphate, that activate the TPCs of mammalian cells, failed to affect the ion channel activity in isolated vacuoles of the mutant plants. (sciencedaily.com)
  • As a result, adenine is converted to another molecule called 2,8-dihydroxyadenine (2,8-DHA). (medlineplus.gov)
  • The sequence of bases in a portion of a DNA molecule, called a gene, carries the instructions needed to assemble a protein. (discovery.org)
  • A gene is a segment of DNA that provides the code to construct a protein or RNA molecule. (msdmanuals.com)
  • In the letter to Wilkins, Chargaff wrote: "I do not believe they knew how to spell adenine when I spoke with them last year. (the-scientist.com)
  • Since the completion of the Human Genome Project, technological improvements and automation have increased speed and lowered costs to the point where individual genes can be sequenced routinely, and some labs can sequence well over 100,000 billion bases per year, and an entire genome can be sequenced for just a few thousand dollars. (genome.gov)
  • The specific order, or sequence, of these bases determines the exact information carried in each gene (for example, instructions for making a specific protein). (cdc.gov)
  • The discussed observations, limited by the small sample size, are suggestive of homozygous adenine insertion variant posing a risk in cyanotic babies with Severe Pulmonary Hypertension. (biomedcentral.com)
  • If the alleles of a gene are the same, the person is homozygous for the gene. (cdc.gov)
  • In Moser's case, her HD gene has 47 CAG repeats which means that she is likely to begin experiencing symptoms by the time she reaches her mid-30s. (reason.com)
  • Cytochrome P450s were the most overexpressed detoxification genes across all resistant phenotypes. (cdc.gov)
  • This means that a change in only one of a person's two copies of the HTT gene can cause the disease. (medicalnewstoday.com)
  • In addition to environmental influences there are gene interactions that affect a person's risk of AD. (reason.com)
  • The data showed that adenine activated AMP-activated protein kinase (AMPK) signaling contributing to autophagic cell death through mTOR in both colon cancer cell lines. (hindawi.com)
  • Anticancer activity of adenine in colon cancer cells is attributable to the activation of apoptotic signaling and in turn the AMPK/mTOR pathway. (hindawi.com)
  • Because alternative RNA splicing allows different types of mRNA molecules to be created from a single gene, it generates the diversity of protein function and structure that is essential to complex organisms. (genomicglossaries.com)
  • Differential gene expression analysis indicated that this isolate formed excessive biofilm by reducing flagellar formation (7.4 to 1,624.1 folds) and overproducing extracellular matrix components including CdrA (4.4 folds), alginate (5.2 to 29.1 folds) and Pel (4.8-5.5 folds). (frontiersin.org)
  • Adenine induced significant apoptosis in HT29 cells, whereas Caco-2 cells exhibited less apoptotic responses. (hindawi.com)
  • It was named necroptosis, as it shares some characteristics of apoptosis, such as rigorous gene-level regulation, and necrosis, an inflammatory cell death in which the cell membrane swells and later breaks, leaking its contents into the intercellular space. (sciencedaily.com)
  • Structure-guided mutational analysis of gene regulation by the Bacillus subtilis pbuE adenine-responsive riboswitch in a cellular context. (ucdenver.edu)
  • This RNA-Seq analysis presents a detailed picture of the candidate detoxification genes and other pathways that are potentially associated with pyrethroid and organophosphate resistance in Ae. (cdc.gov)
  • But already, plans were in the works to move beyond CRISPR's simple scissors, which snip genes out of a DNA sequence. (aps.org)
  • For example, scientists can use sequence information to determine which stretches of DNA contain genes and which stretches carry regulatory instructions, turning genes on or off. (genome.gov)
  • In addition, and importantly, sequence data can highlight changes in a gene that may cause disease. (genome.gov)
  • Highly specific and effective gene silencing of any disease can be achieved by an accurate knowledge of the target mRNA sequence and rational design of its complementary antisense agents for the downregulation of its protein message. (genomicglossaries.com)
  • However, the mechanism by which adenine inhibits the proliferation of cancer cells is sketchy. (hindawi.com)
  • In this study, we investigated the effects of adenine against the proliferation of colon cancer cells. (hindawi.com)
  • In the similar context of mixed tissues , further analysis reveals that the ALKBH1 protein preferentially binds to genes marked by the chromatin signature and has a function to maintain a high H3K4me3/H3K27me3 ratio by impairing the binding of Polycomb repressive complex 2 (PRC2) to the targets, which is required for both the basal and stress-induced expression of the genes . (bvsalud.org)
  • When Emmanuelle Charpentier and Jennifer Doudna won the Nobel Prize in Chemistry in 2020, their CRISPR gene editor had revolutionized medicine, agriculture, and genetics in just a few short years. (aps.org)
  • For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. (phys.org)
  • To do so, the researchers first performed a phylogenetic analysis of the TPC genes in the green plant lineage. (sciencedaily.com)
  • Two groups are investigating how to program the right genes to activate at the right time-and potentially shut down disease. (aps.org)
  • The human genome contains several non-transcribed pseudogenes of this gene. (thermofisher.com)
  • In the concluding review the authors evaluated the effects of natural and chemical compounds on promoter activities of several human DNA repair-associated genes in HeLa S3 cells. (novapublishers.com)
  • Human ortholog(s) of this gene implicated in mucopolysaccharidosis IVA. (mcw.edu)
  • Adenine is a purine derivative which is synthesized in the liver in humans. (hindawi.com)
  • A biological process that is crucial for gene expression in most animal life, including humans. (genomicglossaries.com)
  • Humans have about 20,000 to 23,000 genes. (msdmanuals.com)
  • Each person has two alleles for each gene, one from each parent. (cdc.gov)
  • If the alleles are different, the person is heterozygous for the gene. (cdc.gov)
  • It can also refer to the alleles that a person has for a specific gene. (cdc.gov)
  • For example, genes affect what a person will look like and whether the person might have certain diseases. (cdc.gov)
  • presents an opportunity to manipulate gene expression within the cells to treat various diseases, and acts as a powerful tool for studying gene function utilizing antisense agents to manage the diseases by regulating the expression of the specific factor that actually causes the particular disease. (genomicglossaries.com)
  • Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. (nih.gov)
  • Wan and his collaborators are testing a new method for turning gene expression on and off using a Cas13d RNA enzyme. (aps.org)
  • Here, we find that loss-of-function of the rice ALKBH1 gene leads to increased 6mA in the R-loop regions of the genome but has a limited effect on the overall 6mA level. (bvsalud.org)
  • We realized that the genome of M. polymorpha has three TPC homologs: MpTPC1, 2, and 3, belonging to two distinctive groups, type 1 and type 2 TPC genes. (sciencedaily.com)
  • By CRISPR-Cas9 genome editing, the researchers developed mutant plants that didn't contain functional TPC1, TPC2, or TPC3 genes and double mutant plants that lack functions of both TPC2 and TPC3 genes. (sciencedaily.com)
  • The gene ontology (GO) terms associated with monooxygenase, iron binding, and passive transmembrane transporter activities were significantly enriched in four out of six resistant vs. susceptible comparisons while serine protease activity was elevated in all insecticide-resistant groups relative to the susceptible strain. (cdc.gov)
  • Our findings unravel a function of ALKBH1 to control the balance between the antagonistic histone methylations for gene activity and provide insight into the regulatory mechanism of PRC2-mediated H3K27me3 deposition within the gene body region . (bvsalud.org)
  • By taking bits of a single gene, scientists are using DNA barcoding to identify new species. (yale.edu)
  • Much the same way that a small universal product barcode allows a retailer's scanners to distinguish a box of tissues from a can of green beans, DNA barcoding technology allows scientists to use data from a tiny snippet of a single gene to distinguish one species from the next. (yale.edu)
  • Unlike the type 1 TPC gene, which is well conserved in all land plants, type 2 TPCs were found in algal species. (sciencedaily.com)
  • Adenine significantly inhibited the viability of colon cancer cells, HT29 and Caco-2 cells, in a dose-dependent manner. (hindawi.com)
  • Gene 2006(2): 174-81 [ PubMed abstract ]. (lu.se)
  • These transcript tags were annotated with gene ontology (GO) terms. (biomedcentral.com)
  • Adenine is involved in a variety of cell biological processes and has been explored for pharmacological uses. (hindawi.com)
  • Our findings suggest that adenine inhibits the growth of colon cancer cells. (hindawi.com)
  • Findings suggest that fibrodysplasia ossificans progressiva maps to band 4q27-31, a region that contains at least 1 gene involved in the bone morphogenic protein (BMP) signaling pathway. (medscape.com)
  • They announced their latest progress on the first artificial immune system and CRISPR-Cas12a toggle switch, and shared unexpected nanopore tools for gene mapping and parasitic disease diagnosis, at a press conference during the meeting. (aps.org)
  • People with the APOE4 variant of a gene involved with cholesterol transport are at increased risk of Alzheimer's disease (AD). (reason.com)
  • Nevertheless, researchers are developing data banks that compile possible associations between various genes and the risks of disease. (reason.com)
  • The arrangement of ET-1 gene regulatory region comprising of the proximal promoter elements and 5′UTR, upstream of the 5 exons is represented schematically in Fig. 1 A. (biomedcentral.com)