Gene saccharomyces cerevisiae proteins. Medical search. Frequent questions

Precise regulation of transcription in gene expression is critical for all aspects of normal organism form, fitness, and function and even minor alterations in the level, location , and timing of gene expression can result in phenotypic variation within and between species including evolutionary innovations and human disease states. (bvsalud.org)
The function of specific proteins from this organism are the subject of intense scientific interest and have been used to derive basic understanding of the functioning similar proteins in higher eukaryotes. (musc.edu)
The yeast S. cerevisiae has been widely used as a model eukaryotic organism as many cellular processes are conserved to humans, and comparatively large amounts of genomic, metabolomic, and proteomic data is readily available. (biomedcentral.com)

Saccharomyces cerevisiae S288C 14-3-3 family protein BMH1 (BMH1), partial mRNA. (genscript.com)

HyCCAPP as a tool to characterize promoter DNA-protein interactions in Saccharomyces cerevisiae. (mcw.edu)
Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors. (rochester.edu)
Functional and physical interactions among Saccharomyces cerevisiae α-factor receptors. (rochester.edu)
Differential interactions of fluorescent agonists and antagonists with the yeast G protein coupled receptor Ste2p. (rochester.edu)
No yeast two-hybrid interactions found for this protein. (yeastrc.org)
Mechanism of Regulation of Intrachromatid Recombination and Long-Range Chromosome Interactions in Saccharomyces cerevisiae. (musc.edu)
Gene function prediction from congruent synthetic lethal interactions in yeast. (thebiogrid.org)
We predicted gene function using synthetic lethal genetic interactions between null alleles in Saccharomyces cerevisiae. (thebiogrid.org)

Saccharomyces cerevisiae is a useful eukaryotic expression system for mitochondrial membrane proteins due to its ease of growth and ability to provide a native membrane environment. (nih.gov)
Fluctuations in external salinity force eukaryotic cells to respond by changes in the gene expression of proteins acting in protective biochemical processes, thus counteracting the changing osmotic pressure. (nih.gov)
By sequence analyses, CRS5 encodes a small molecular weight cysteine-rich protein with an amino acid sequence bearing all the features of a eukaryotic metallothionein. (nih.gov)
Eukaryotic gene expression is a cumulative outcome of a multitude of molecular processes, including transcription, mRNA splicing, stability and translation, chromatin modification, as well as protein stability and modification. (nature.com)
Ubiquitin is a protein of 76 amino acid residues, found in all eukaryotic cells and whose sequence is extremely well conserved from protozoan to vertebrates. (embl.de)
The basic helix-loop-helix (bHLH) proteins comprise a eukaryotic transcription factor family involved in multiple biological processes. (umass.edu)
The three-dimensional structure consists of a central four-stranded parallel beta-sheet flanked by five alpha-helices, revealing an overall structural topology similar to those of the eukaryotic LMW-PTPs, such as human HCPTP-A, bovine BPTP, and Saccharomyces cerevisiae LTP1, and to those of the bacterial LMW-PTPs MPtpA from Mycobacterium tuberculosis and YwlE from Bacillus subtilis. (rcsb.org)
Evidence that the gene encodes a highly conserved copper-transporting adenosine triphosphatase (ATPase) has stimulated investigation of the molecule's normal function in prokaryotic and eukaryotic systems. (medscape.com)

The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. (antibodies-online.com)

Furthermore, the interaction of mitogen-activated protein kinase HwHog1 and RNA polymerase II with the chromatin in cells adapted to an extremely hypersaline environment was analyzed. (nih.gov)
In comparison with the salt-sensitive S. cerevisiae, this yeast shows a different set of genes being expressed at high salt concentrations and interacting with HwHog1 MAP kinase, suggesting atypical processes deserving of further study. (nih.gov)
Arrestin, the Snf1 Protein Kinase, and the Bmh2 14-3-3 Protein. (genscript.com)
Protein kinase domain. (unl.edu)
Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase. (unl.edu)
Serine/threonine kinases (STKs), mitogen-activated protein kinase (MAPK) kinase kinase (MAPKKK) subfamily, catalytic (c) domain. (unl.edu)
The MAPKKK subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase. (unl.edu)
A protein kinase encoded by the Saccharomyces cerevisiae CDC28 gene and required for progression from the G1 PHASE to the S PHASE in the CELL CYCLE . (nih.gov)
Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. (tamu.edu)
bgs13, which has a disruption in a gene homologous to Saccharomyces cerevisiae protein kinase C (PKC1), gave enhanced secretion of most recombinant proteins that were tested, raising the possibility that it has the universal super-secreter phenotype needed in an industrial production strain of P. pastoris . (pacific.edu)

9. Transcription of the AAC1 gene encoding an isoform of mitochondrial ADP/ATP carrier in Saccharomyces cerevisiae is regulated by oxygen in a heme-independent manner. (nih.gov)
AluI sites in inactive mouse promoters are accessible in some cells, implying that transcription factors could bind without activating the gene. (nih.gov)
Title: The Hsp70 homolog Ssb and the 14-3-3 protein Bmh1 jointly regulate transcription of glucose repressed genes in Saccharomyces cerevisiae. (genscript.com)
Title: Yeast 14-3-3 protein functions as a comodulator of transcription by inhibiting coactivator functions. (genscript.com)
Title: The yeast 14-3-3 proteins BMH1 and BMH2 differentially regulate rapamycin-mediated transcription. (genscript.com)
Title: 14-3-3 (Bmh) proteins regulate combinatorial transcription following RNA polymerase II recruitment by binding at Adr1-dependent promoters in Saccharomyces cerevisiae. (genscript.com)
It is known that TSN is critically involved in virtually all pathways of gene expression, ranging from transcription to RNA silencing. (nature.com)
Figure 1 is a venn diagram detailing the significant temperature responses of gene transcription. (openwetware.org)
Genes involved in growth limiting nutrient intake showed different transcription. (openwetware.org)
Transcription was induced for genes in the metabolism of stored carbohydrates. (openwetware.org)
But at the steady state 12C chemostat conditions the transcription of these genes was not affected. (openwetware.org)
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. (antibodies-online.com)
This gene encodes for a bHLH transcription factor, which inhibits osteogenic differentiation by transc. (uni-marburg.de)

Differences in evolutionary rates between pairs of genes ( dN & dS ) were then compared to their functional similarities ( sGO ), which were measured using Gene Ontology (GO) annotations. (nih.gov)
2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. (yeastrc.org)
Number of Gene Ontology (GO) annotations for this target, consisting of the sum of GO Functions and GO Processes. (nih.gov)
Classes for this protein according to by Drug Target Ontology (DTO). (nih.gov)

Genome-wide gene expression responses to experimental manipulation of Saccharomyces cerevisiae repressor activator protein 1 (Rap1) expression level. (bvsalud.org)
To fill this knowledge gap, we used a strain with a tetracycline -titratable promoter replacing wild-type regulatory sequences of RAP1 to systematically reduce the expression level of RAP1 and followed this with RNA sequencing ( RNA-seq ) to measure genome -wide gene expression responses. (bvsalud.org)
Myung, K., Chen, C. & Kolodner, R. D. Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae . (nature.com)
Although analyses that give information on the expression of a few genes provide insight and have been responsible for a large proportion of the bacterial pathogenesis literature currently available, our ultimate goal is to understand expression changes across the whole genome. (cdc.gov)
The additional information generated by whole genome studies goes far beyond that derived by characterizing in isolation more genes and gene products, because analysis of the whole genome allows complete regulatory networks to be identified and characterized. (cdc.gov)
A second group of methods, which includes DNA microarrays and proteomics, have advantages that overcome the limitations implicit in signature-tagged mutagenesis and in vivo expression technology, namely, the ability to directly measure expression (gene or protein) levels on a true genome-wide scale, but their application to analysis of bacterial pathogens during real infections is still in its infancy. (cdc.gov)
Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure. (cam.ac.uk)
Red boxes indicate regions of the S.cerevisiae genome to be targeted, while black boxes signify selection markers. (igem.org)
A putative low molecular weight protein tyrosine phosphatase (LMW-PTP) was identified in the genome sequence of the bacterial pathogen, Campylobacter jejuni. (rcsb.org)

Proteins of the DME family evidently arose by an internal gene duplication event as the first halves of these proteins are homologous to the second halves. (tcdb.org)
The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and 550 human proteins. (unl.edu)
IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. (wikidata.org)

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. (nih.gov)

In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. (antibodies-online.com)
Although the Sdhp has no direct role in transcriptional regulation and the flux through the corresponding reaction under the studied conditions is very low, deletion of SDH3 resulted in significant changes in the expression of several genes involved in various cellular processes ranging from metabolism to the cell-cycle. (biomedcentral.com)
The coupling between metabolism and oxidative phosphorylation is also reflected in the tight transcriptional regulation of the TCA cycle, for example, as observed in Saccharomyces cerevisiae during the diauxic shift between fermentative and oxidative metabolism. (biomedcentral.com)

By biochemical methods Mad1 was predicted to encode a 90kD, 718-residue, coiled-coil protein with a characteristic rod shape in 1995. (wikipedia.org)
3. Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. (nih.gov)
For instance, genes that encode physically interacting proteins tend to evolve at similar rates (Fraser et al. (nih.gov)
S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein. (wikidata.org)

2004). The characterization of such relationships has the potential to reveal important clues as to the function of individual genes. (nih.gov)
Although a detailed understanding of virulence mechanisms of C.albicans may ultimately lead to novel approaches to combat infections caused by this pathogen, the identification and characterization of essential genes as potential targets for the development of antifungal drugs is a strategy favoured by most pharmaceutical companies. (uni-wuerzburg.de)
Identification and characterization of the specific genes that determine longevity and contribute to aging and senescence in several species including humans are central to understanding the fundamental molecular mechanisms that govern aging and senescence. (nih.gov)
1989. Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae. . (ucsb.edu)
Preliminary characterization of four bgs mutants showed that they differed in the ability to enhance the export of other reporter proteins. (pacific.edu)

Purification of transmembrane proteins from Saccharomyces cerevisiae for X-ray crystallography. (rochester.edu)
FIGURE 2: TMTC3 and TMTC4 are transmembrane proteins with their TPR domains facing the ER lumen. (xenbase.org)

I. Construction and genetic analysis of yeast mutants encoding the ADP/ATP carrier protein of mitochondria. (nih.gov)
Their genes are transcribed and translated by a genetic system residing in the matrix of the organelle. (molbiolcell.org)
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. (thebiogrid.org)
The goals of the Genetic and Molecular Basis of Longevity Request for Applications (RFA) are to identify genes which promote longevity and delay the onset of senescence, termed Longevity Assurance Genes (LAGs), and determine the biochemical functions and molecular mechanisms of action of these LAGs. (nih.gov)

In the early 90s, yeast genes were identified which mutations resulted in a defect in mitotic arrest in response to microtubule disassembly (mitotic arrest deficient genes - MAD genes). (wikipedia.org)
12. Mutations in AAC2, equivalent to human adPEO-associated ANT1 mutations, lead to defective oxidative phosphorylation in Saccharomyces cerevisiae and affect mitochondrial DNA stability. (nih.gov)
Identification of destabilizing and stabilizing mutations of Ste2p, a G protein-coupled receptor in Saccharomyces cerevisiae. (rochester.edu)
Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. (thebiogrid.org)
Mutations in the LBR gene cause Greenberg dysplasia. (medlineplus.gov)
LBR gene mutations involved in Greenberg dysplasia lead to loss of the sterol reductase function of the lamin B receptor, and research suggests that this loss causes the condition. (medlineplus.gov)
which means both copies of the gene in each cell have mutations. (medlineplus.gov)

Anaerobic xylose fermentation by recombinant Saccharomyces cerevisiae carrying XYL1 , XYL2 , and XKS1 in mineral medium chemostat cultures. (microbiologyresearch.org)

Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. (joplink.net)
The following BMH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). (genscript.com)
These sequences represent the protein coding region of the BMH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. (genscript.com)
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. (genscript.com)
One rich source of evolutionary information is the relative rates of gene sequence divergence, and in this report we explore the con- nection between gene evolutionary rates and function. (nih.gov)
These results are consistent with a mode of action for natural selection that is based on similar rates of elimination of del- eterious protein coding sequence variants for functionally related genes. (nih.gov)
It is caused by nucleotide sequence changes within or in proximity of the TWIST1 gene. (uni-marburg.de)
Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway. (wikidata.org)

We also compared the expression of RAP1 to five different genes related to DNA repair pathway and found that decreasing RAP1 downregulated four of those five genes . (bvsalud.org)
The high-osmolarity glycerol (HOG) signaling pathway is essential for the efficient up-regulation of the osmoresponsive genes. (nih.gov)
2006) Mxr1p, a key regulator of the methanol utilization pathway and peroxisomal genes in Pichia pastoris . (rug.nl)
The covalent attachment of the polypeptide ubiquitin to proteins marks them for degradation by the ubiquitin/26S proteasome-dependent degradation pathway. (embl.de)
A multi-pathway perspective on protein aggregation: implications for control of the rate and extent of amyloid formation. (nih.gov)
Congruent gene pairs, defined as sharing synthetic lethal partners, are in single pathway branches. (thebiogrid.org)
The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. (wikidata.org)

Non-synonymous ( dN ) and synony- mous ( dS ) substitution rates were calculated for 1,095 orthologous gene sets common to S . cerevisiae and six other closely related yeast species. (nih.gov)
Phylogenetic profi le methods, which evaluate patterns of gene presence and absence across sets of species, work because natural selec- tion tends to maintain functionally related genes as coherent sets within evolutionary lineages. (nih.gov)
orthologue:A gene in two or more species that has evolved from a common ancestor. (openwetware.org)
Proteins obtained from the species SACCHAROMYCES CEREVISIAE. (musc.edu)
Find HIRIP3 Proteins for a variety of species such as anti-Human HIRIP3, anti-Mouse HIRIP3. (antibodies-online.com)

The transcriptional response in hypersaline-adapted and hypersaline-stressed cells showed that only a subset of the identified genes responded to acute salt-stress, whereas all were differentially expressed in adapted cells. (nih.gov)
We therefore explored the physiological and transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3 , that codes for an essential subunit of the Sdhp. (biomedcentral.com)

However, one protein, Tudor staphylococcal nuclease (TSN, also known as Tudor-SN, SND1 or p100) appears to act in most of the gene expression pathways. (nature.com)
Phylogenetic analysis of ubiquitin sequences reveals greater variability among lower eukaryotes and defines essential residues, many of which are conserved among the three ubiquitin-like proteins known to undergo parallel ligation pathways. (embl.de)
Within this hierarchy, a single ubiquitin-activating enzyme provides charged intermediates to multiple targeting pathways defined by cognate ubiquitin carrier protein (E2)/ligase (E3) pairs. (embl.de)
Collectively, these results support the model that yeast bHLH proteins coordinate different biological pathways. (umass.edu)
Phenotypic and protein interaction data indicate that synthetic lethal gene pairs function in parallel or compensating pathways. (thebiogrid.org)

Here, by employing a systematic mass spectrometry-based approach, we discovered the previously uncharacterized membrane protein Mrx15 that interacts via a soluble C-terminal domain with the large ribosomal subunit. (molbiolcell.org)
Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain. (wikidata.org)
It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. (nih.gov)
Inner nuclear membrane protein LBR preferentially interacts with DNA secondary structures and nucleosomal linker. (medlineplus.gov)

Our approach is based on a growing body of literature that points to the connections between various phenotypic aspects of genes and their rates of evolution (Wall et al. (nih.gov)

Taken together, our data reveal how these ribosome receptors organize membrane protein biogenesis in mitochondria. (molbiolcell.org)
The mitochondrial ribosomes (mitoribosomes) synthesize, almost exclusively, membrane proteins that are subunits of oxidative phosphorylation complexes. (molbiolcell.org)
Deducing the Symmetry of Helical Assemblies: Applications to Membrane Proteins. (rochester.edu)
Guided reconstitution of membrane protein fragments. (rochester.edu)
Structure of the integral membrane protein CAAX protease Ste24p. (rochester.edu)
The DME family is a large family of integral membrane proteins with sizes ranging from 287 to 310 amino acyl residues and exhibiting 10 putative α-helical transmembrane spanners (TMSs). (tcdb.org)
Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. (unl.edu)
The protein expression profiles of cytoplasm and membrane/nuclei fractions were checked using protein two-dimensional electrophoresis (2-DE). (hindawi.com)
More remarkably, these proteins appear to comprise a preformed effector-G beta subunit assembly and function at the endosome rather than at the plasma membrane. (tamu.edu)

8. ADP/ATP translocator is essential only for anaerobic growth of yeast Saccharomyces cerevisiae. (nih.gov)
Table 1 shows the characteristics of Saccharomyces cerevisiae grown in ammonium and glucose limited anaerobic chemostats. (openwetware.org)

Title: General Amino Acid Control and 14-3-3 Proteins Bmh1/2 Are Required for Nitrogen Catabolite Repression-Sensitive Regulation of Gln3 and Gat1 Localization. (genscript.com)
BMH2 also attenuates the activation of genes sensitive to nitrogen catabolite repression. (genscript.com)
This is seen in the negative regulation of genes for glucose catabolite repression and nitrogen catabolite repression genes. (openwetware.org)

5. The molecular basis for relative physiological functionality of the ADP/ATP carrier isoforms in Saccharomyces cerevisiae. (nih.gov)
Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. (antibodies-online.com)
Alternative splicing of this gene results in three transcript variants encoding two different isoforms. (nih.gov)

Our results suggest that a decrease in mRNAs encoding high-affinity/active sugar transport systems may be a widespread and conserved mechanism in yeasts, limiting expression of these proteins whenever their activity is dispensable. (microbiologyresearch.org)

Mad1 is a non-essential protein which in yeast has a function in the spindle assembly checkpoint (SAC). (wikipedia.org)
Title: The 14-3-3 protein Bmh1 functions in the spindle position checkpoint by breaking Bfa1 asymmetry at yeast centrosomes. (genscript.com)
The central coiled coil of the essential spindle pole component Spc110p spans the distance between the central and inner plaques of the Saccharomyces cerevisiae spindle pole body (SPB). (sdbonline.org)
Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism. (musc.edu)

In 2001, proteins originally defined as belonging to the UmuC/DinB/Rev1/Rad30 superfamily and involved in mutagenesis and TLS DNA synthesis were designated as Y-family polymerases [27]. (nih.gov)

Also included in this subfamily are the cell division control proteins Schizosaccharomyces pombe Cdc7 and Saccharomyces cerevisiae Cdc15. (unl.edu)

Mitochondrial gene expression in Saccharomyces cerevisiae is responsible for the production of highly hydrophobic subunits of the oxidative phosphorylation system. (molbiolcell.org)

4. Yeast ADP/ATP carrier (AAC) proteins exhibit similar enzymatic properties but their deletion produces different phenotypes. (nih.gov)
Owing to its high protein-protein binding affinity coexistent with enzymatic activity, TSN can exert its biochemical function by acting as both a scaffolding molecule of large multiprotein complexes and/or as a nuclease. (nature.com)

The co-evolution of functionally related yeast genes points to the relevance of specifi c function for the effi cacy of natural selection and underscores the utility of gene evolutionary rates for functional predictions. (nih.gov)
New yeast- Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. (microbiologyresearch.org)

While much is known about the roles of Rap1 in gene regulation and numerous cellular processes, the response of Rap1 target genes to systematic titration of RAP1 expression level remains unknown. (bvsalud.org)
this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. (unl.edu)
Here we demonstrate that growing yeast cells show a very repeatable and robust cyclic variation of the concentration of proteins with different cellular functions. (hal.science)
Endoplasmic reticulum transmembrane protein TMTC3 contributes to O-mannosylation of E-cadherin, cellular adherence, and embryonic gastrulation. (xenbase.org)

Multiple bHLH proteins regulate CIT2 expression in Saccharomyces cerevisiae. (umass.edu)
The current study tested the ability of all nine S. cerevisiae bHLH proteins to regulate the CIT2 gene. (umass.edu)
Because the environment encountered within a living host will be quite different from the external environment, pathogens must be able to regulate the necessary genes in coordination as they move from the environment to the host and from one host niche to another. (cdc.gov)

Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. (nih.gov)

Both Bmh1 and Bmh2 associate with the promoters of at least some of these genes. (genscript.com)
The functions and promoters of these genes were then looked at. (openwetware.org)

In Saccharomyces cerevisiae , the TF with the greatest number of putative regulatory targets is the essential gene Repressor Activator Protein 1 (RAP1). (bvsalud.org)

This increase in genes for making proteins didn't show up in the biomass composition for glucose limited conditions but it did for ammonium limited. (openwetware.org)
While Gxf1p seems to be fully functional in S. cerevisiae , the symporter Gxs1p exhibits very low glucose/xylose transport activity, which could not be ascribed to insufficient production of the protein or incorrect subcellular localization. (microbiologyresearch.org)
The observed decrease in GXS1 transcript levels seems to be related to an enhanced glucose influx mediated by glucose facilitator protein(s), and not to a specific interaction between Gxs1p and other transporters. (microbiologyresearch.org)

An uncommon osmoresponsive set of 95 differentially expressed genes was identified. (nih.gov)
Interaction with HwHog1 was shown for 36 of the 95 differentially expressed genes. (nih.gov)
Proteins differentially expressed between control and SCU-treated group, control and HR group, or HR and SCU + HR group were identified using mass spectrometry (MS/MS). Possible interaction network of these target-related proteins was predicted using bioinformatic analysis. (hindawi.com)
Proteins differentially expressed between control and SCU-treated group and proteins differentially expressed between HR and SCU + HR group were considered as possible target-related proteins of SCU. (hindawi.com)
At the same time, proteins differentially expressed between control and HR group were also identified to provide information about possible proteins involved in HR injury. (hindawi.com)

Ligand binding and activation of AhR induces nuclear localization and heterodimerization with the AhR nuclear transporter (ARNT) protein ( Whitlock 1999 ). (nih.gov)
HXT3, HXT2, and HXT4 are hexose transporter genes and they showed increases at 12C. (openwetware.org)

TSN is an evolutionarily conserved protein having a pivotal role in the regulation of gene expression. (nature.com)
Being true for all living organisms, accurate spatio-temporal regulation of gene expression is a fundamental mechanism underlying development, homeostasis and adaptation to the environment. (nature.com)
These properties make them ideal for combinatorial regulation of gene expression. (umass.edu)

2006) PEX genes in fungal genomes: common, rare or redundant. (rug.nl)

2006), synthetic lethal gene pairs (Tong et al. (nih.gov)

Additionally, we found that Rap1 functions as an activator of ribosomal protein genes and a repressor for HM loci genes consistent with predictions from the literature . (bvsalud.org)
Innate immunity to yeast prions: Btn2p and Cur1p curing of the [URE3] prion is prevented by 60S ribosomal protein deficiency or ubiquitin/proteasome system overactivity. (nih.gov)

This vector system is amenable to the expression and purification of multi-subunit protein complexes. (nih.gov)
The dnaE gene encoding the catalytic a-subunit of pol III was sequenced in 1987 [14] (accession P10443). (nih.gov)
The results indicated that proteins such as p27BBP protein (EIF6), heat shock 60 kDa protein 1 (HSPD1), and chaperonin containing TCP1 subunit 6A isoform (CCT6A) might play important roles in the effects of SCU. (hindawi.com)

This activated heterodimer binds to cognate cis -acting sequences [dioxin response elements (DREs)], located in the 5′-regulatory region of target genes. (nih.gov)

Binding of fluorinated phenylalanine alpha-factor analogues to Ste2p: evidence for a cation-pi binding interaction between a peptide ligand and its cognate G protein-coupled receptor. (rochester.edu)
Interestingly, deleting the INO2, INO4 genes or the cognate E-box revealed phosphate induction of CIT2 expression. (umass.edu)

Biochemical analysis of distinct AAC1 and AAC2 proteins in yeast. (nih.gov)
This gene expression study was performed in conjunction with a cancer bioassay conducted by the National Toxicology Program (NTP), which included interim sacrifices (13, 30, and 52 weeks) to investigate tissue dosimetry, histopathology, and other biochemical and molecular responses throughout the 2-year study. (nih.gov)
Information transfer via BLAST rests on the fact that molecular evolution is a conservative process marked by the preservation of biochemical function among related genes. (nih.gov)

However, we now have a number of methods that allow identification of genes critical for survival in a host as well as methods that allow direct measurement of gene expression during interaction with a host. (cdc.gov)

Biosynthesis genes for glycogen and trehalose can be induced by stress such as cold shock. (openwetware.org)

Anatomy21

Organisms14

Diseases1

Chemicals and Drugs117

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Phenomena and Processes88

Disciplines and Occupations1

Technology, Industry, Agriculture3

Information Science4

Health Care3

Organism3

S288c1

Interactions8

Eukaryotic8

Similar to Saccharomyces cerevisiae1

Kinase10

Transcription13

Ontology4

Genome9

Homologous3

Encodes a protein1

Metabolism3

Encode4

Characterization5

Transmembrane proteins2

Genetic4

Mutations7

Recombinant1

Sequence8

Pathway7

Species5

Transcriptional response2

Pathways5

Interacts4

Phenotypic1

Membrane9

Anaerobic2

Nitrogen catabolite repression3

Isoforms3

Yeasts1

Spindle4

20011

Schizosaccharomyces1

Oxidative1

Enzymatic2

Yeast genes2

Cellular4

Regulate3

Recombination1

Promoters2

Putative1

Glucose3

Differentially5

Transporter2

Regulation of gene ex3

Fungal1

Synthetic lethal gene pairs1

Ribosomal protein2

Subunit3

Sequences1

Cognate2

Biochemical3

Interaction1

Biosynthesis1