AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesTechnology, Industry, AgricultureHealth Care
Integumentary System Physiological PhenomenaDigestive System Physiological PhenomenaDigestive System NeoplasmsDigestive System DiseasesDigestive SystemDigestive System and Oral Physiological PhenomenaNervous System Physiological PhenomenaDental Physiological PhenomenaReproductive and Urinary Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaCirculatory and Respiratory Physiological PhenomenaSports Nutritional Physiological PhenomenaDigestive System ProcessesReproductive Physiological PhenomenaPhysiological PhenomenaElder Nutritional Physiological PhenomenaDigestive System FistulaUrinary Tract Physiological PhenomenaGastrointestinal TractClemastineMusculoskeletal Physiological PhenomenaGastrointestinal NeoplasmsDigestive System AbnormalitiesDiagnostic Techniques, Digestive SystemGastrointestinal DiseasesVirus Physiological PhenomenaIntestinesPancreasLarvaStomachBlood Physiological PhenomenaTissue DistributionPlacebo EffectFoxesMental HealingPlacebosDrug IndustrySuggestionAcupuncture Therapy
MetabolismGeneticEnzymesImmune systemMicrobialMutationsIndividual'sDiseasesPhysiologyMidgutDeletionPolymorphismsOrgan systemsTractStressGlucoseAutonomic nervouRespiratoryMediatePsychologicalLungsReproductiveTissuePhenotypeBiological systemsDiseaseGenomicRecessiveBodyDisordersOccurInteractionsNervousMechanismsDiabetesCellsConditionsClusterEnvironmentalExpressionMuscularResponseDietaryCellBiologyFoundComplexResponsibleIssuesUnderstandMouth
Metabolism3
  • Our findings shed light on the possible cellular basis and transcriptomic regulatory clues for the low metabolism in giant pandas and helped to understand physiological adaptation response to nutrient stress. (biomedcentral.com)
  • lncRNAs mediate glucose and lipid metabolism under physiological and pathological conditions and contribute to various metabolism disorders. (frontiersin.org)
  • While previously identified copper-related genes were not differentially expressed in tolerant vs. sensitive strains, genes involved in metabolism, reproduction, and protease induction contributed to the differential stress response. (biomedcentral.com)
Genetic4
  • Genetic data also will be useful in identifying mutations and polymorphisms that predispose to some of the acquired diseases of the nervous system, some of which are discussed in this article. (medscape.com)
  • For example, individual factors such as the genetic background, the age, the development of the immune system, the geographical location or any dietary modifications of short or longer durations may influence the gut microbiota composition. (bmj.com)
  • Overall, by combining genome-wide approaches with environmental association analysis, and functional analysis of candidate genes, our study provides a unique perspective on the genetic and environmental factors that shape copper tolerance in natural D. melanogaster populations and identifies new genes, transposable elements, and physiological traits involved in this complex phenotype. (biomedcentral.com)
  • With the immense physiological and genetic diversity across the microbial world, there is potential to develop and engineer novel and model microorganisms with unique capabilities and biosynthetic pathways beyond what is currently used in industry. (energy.gov)
Enzymes3
  • By the mid 1980s, techniques largely had switched from those of the biochemistry of intermediates and enzymes to the identification of mutations in genes. (medscape.com)
  • Searching for the possible site of action of the hormone, I tested the effects of treating adipocytes with phospholipases and proteases on the assumption that, if the surface or plasma membrane contains insulin recep- tors, these digestive enzymes might prevent insulin action. (nih.gov)
  • (10) When introduced to primary cultures, acinar cells progressively lose their capacity to secrete digestive enzymes and dedifferentiate. (gbmn.org)
Immune system5
  • This dysbiosis may influence the degree of hepatic steatosis, inflammation and fibrosis through multiple interactions with the host's immune system and other cell types. (bmj.com)
  • Prolonged, uninterrupted exposure to stress slowly and gradually erodes the immune system. (globalhealing.com)
  • These case studies will be used to teach the relevant basic biological tenets of genetics, molecular genetics, cell biology, the immune system, ecology, epidemiology, and clinical medicine. (nau.edu)
  • Supports a strong immune system. (tlsslim.com)
  • Antibodies are proteins that your body makes as part of the learned immune system. (nih.gov)
Microbial4
  • However, microbial pathogenesis is often studied in mucus-free environments that lack the geometric constraints and microbial interactions in physiological three-dimensional mucus gels. (nih.gov)
  • The GSP's portfolio includes research that builds on a foundation of genomic data and combines experimental physiology studies with "omics"-driven tools of modern systems biology and computational approaches to harness the power of microorganisms and microbial communities as cellular factories. (energy.gov)
  • It is thus necessary to develop ways to design and control the functional capabilities within living systems to harness the biosynthetic processing power of the microbial world. (energy.gov)
  • Lariza is a PhD student from Federal University of Minas Gerais (Brazil) who is investigating microbial community and overall performance of biofilm-based systems applied to anaerobically treated sewage under warm climate conditions. (utoronto.ca)
Mutations7
  • use GALACTOSYLGALACTOSYLGLUCOSYLCERAMIDASE 1983-2008 MH - Acrocallosal Syndrome UI - D055673 MN - C10.500.70 MN - C16.131.666.70 MS - A condition caused by autosomal recessive gene mutations leading to hypogenesis or absence (agenesis) or of CORPUS CALLOSUM, the band of nerve fibers joining the two CEREBRAL HEMISPHERES. (nih.gov)
  • Data from the Human Genome Project surely will be useful in identifying mutations in the thousands of genes that must underlie inherited diseases of the central and peripheral nervous system. (medscape.com)
  • Until the genes and their mutations that underlie neurological disease are characterized, inherited disorders have to be defined the way clinicians have been classifying disease over the last 2 centuries. (medscape.com)
  • NCIt Code NCIt PT NICHD NRNT PT NICHD NRNT SY NCIt Definition NICHD Definition NCIt Code of NICHD Parent NICHD Parent PT NCIt Code of second NICHD Parent NICHD second Parent PT NCIt Code of NICHD Subset NICHD PT of NICHD Subset C98863 2-Methylbutyryl-CoA Dehydrogenase Deficiency Butyryl-CoA Dehydrogenase Deficiency A rare autosomal recessive inherited disorder caused by mutations in the ACADSB gene. (nih.gov)
  • C3492 Specific Enzyme Deficiency C99147 Neonatal Research Network Terminology C98674 3-Methylcrotonyl-CoA Carboxylase Deficiency Methylcrotonyl-CoA Carboxylase Deficiency An autosomal recessive inherited disorder caused by mutations in the MCCC1 or MCCC2 genes. (nih.gov)
  • C85866 Autosomal Recessive Hereditary Disorder C3492 Specific Enzyme Deficiency C99147 Neonatal Research Network Terminology C98683 3-Methylglutaconic Aciduria Type 1 3-Methylglutaconic Aciduria Type 1 3-methylglutaconic aciduria inherited in an autosomal recessive pattern and caused by mutations in the AUH gene. (nih.gov)
  • C85866 Autosomal Recessive Hereditary Disorder C3492 Specific Enzyme Deficiency C99147 Neonatal Research Network Terminology C98699 5 Alpha Steroid Reductase 2 Deficiency 3-Oxo-5 Alpha-Steroid Delta 4-Dehydrogenase Deficiency An autosomal recessive inherited disorder caused by mutations in the SRD5A2 gene. (nih.gov)
Individual's1
  • When faced with environmental change, an individual's physiological fitness requires that its organ systems functionally adapt. (stanford.edu)
Diseases1
  • The fibrinolytic system is involved in many physiological functions, among which the important members can interact with each other, either synergistically or antagonistically to participate in the pathogenesis of many diseases. (bvsalud.org)
Physiology1
  • She provided an overview of the male urogenital system and highlighted unique aspects of prostate physiology. (nih.gov)
Midgut2
  • Additionally, the greatest transcriptomic and physiological responses to copper toxicity were seen in the midgut, where we found that preservation of gut acidity is strongly linked to greater tolerance. (biomedcentral.com)
  • We have found that when dietary load increases, midgut stem cells activate a reversible growth program that increases total intestinal cell number and digestive capacity. (stanford.edu)
Deletion1
  • Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. (lookformedical.com)
Polymorphisms2
  • Therefore, this review will elaborate on PAI-1 structure, the dual value of PAI-1 in different digestive system tumors, gene polymorphisms, the uPA-dependent and -independent mechanisms of regulatory networks, and the drugs targeted by PAI-1 to deepen the comprehensive understanding of PAI-1 in digestive system tumors. (bvsalud.org)
  • This was done by a large number of techniques that make use of DNA fragments (restriction fragment-length polymorphisms) so as to permit linkage mapping and gene sequencing. (medscape.com)
Organ systems1
  • Examines histology and human organ systems including integumentary, skeletal, muscular and nervous. (nau.edu)
Tract1
  • Mucus is a biological gel that lines all wet epithelia in the body, including the mouth, lungs, and digestive tract, and has evolved to protect the body from pathogenic infection. (nih.gov)
Stress3
  • This is true of both psychological (mental) and physiological (physical) stress, including environmental stress . (globalhealing.com)
  • Stress produces a physiological response - your heart races, your face and body feel hot, you sweat, and your breathing may become shallow and fast. (globalhealing.com)
  • High-stress events activate the autonomic nervous system and produce the symptoms described above and inhibit the body's detoxification process. (globalhealing.com)
Glucose1
  • My interest in receptors began in the early 60's, when I uncorked the means of freeing adipocytes from their tissue matrix by coHagenase treatment and found that insulin at physiological concentrations stimulated glucose upta- ke(1). (nih.gov)
Autonomic nervou1
Respiratory2
  • Wang, Z, Li K, Huang, W (2019), records that quantities of NEAT1 and thus Paraspeckles are increased in digestive system tumours and respiratory cancers. (wikipedia.org)
  • Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death (see WARNINGS , Drug Interactions ). (nih.gov)
Mediate1
  • Other viscous polymer solutions did not match the biofilm disruption caused by mucins, suggesting that mucin-specific properties mediate the phenomenon. (nih.gov)
Psychological1
  • This assignment will discuss how one is aged gracefully from physiological, psychological and social aspects. (eduzaurus.com)
Lungs1
  • By shunting blood away from less vital organs like the skin and digestive system and instead sending it toward the lungs, heart, kidneys, brain, and liver, the chances of survival are increased. (biologydictionary.net)
Reproductive1
Tissue2
  • not only can gene expression be manipulated and lineages traced at single-cell and whole-tissue levels, but complete population counts of all cell types are possible. (stanford.edu)
  • The physiological tissue context of newly isolated acini produced by collagen digestion has been lost even though they have intact secretory vesicles and secretory stimulation (which includes activation of intracellular proteases). (gbmn.org)
Phenotype1
  • This hypothesis will be analyzed in terms of the thrifty phenotype paradigm according to which adverse prenatal events can cause differential gene expression resulting in a phenotype that is better suited, metabolically, for a deprived environment. (jaredreser.com)
Biological systems6
  • Methods of scientific inquiry and behavior of matter and energy in biological systems are explored. (nau.edu)
  • The U.S. Department of Energy's (DOE) Genomic Science program, managed within the Office of Biological and Environmental Research (BER), supports basic research aimed at identifying the foundational principles that drive biological systems.GSP aims to solve critical challenges in energy security and environmental stewardship. (energy.gov)
  • To enable a future where biological systems can be designed and modified for desired specific outcomes and deliver positive impacts for the environment and the bioeconomy, the GSP solicited applications in two subtopic areas for this Funding Opportunity Announcement (FOA): sustainable bioenergy and polymer upcycling. (energy.gov)
  • Realizing this potential requires a fundamental understanding of how biological systems behave. (energy.gov)
  • The past decade has seen tremendous technological advances in the development of multiomics tools, high-throughput phenotypic screening approaches, and computational modeling methods to analyze, modify, and select specific functional properties of biological systems. (energy.gov)
  • These kinetic parameters are used to parametrize genome-scale models and improve their performance for better phenotypic prediction of different biological systems. (utoronto.ca)
Disease3
  • Obesity increases the risk of have metabolic syndrome which includes cardiovascular disease, heart disease, stroke etc. which is detrimental to various systems of body. (eduzaurus.com)
  • Determining the relative impact of evolutionary causation on neuropathological disease should prove informative for medical and gene therapeutic treatment modalities. (jaredreser.com)
  • The classical phenomenon of Exteriorization of Disease should occur in every case and as a rule, it happens with the correct remedy. (yes4homeopathy.com)
Genomic1
  • lncRNAs can be categorized into intergenic, intronic, bidirectional, sense, and antisense lncRNAs, depending on their genomic position relative to nearby protein-coding genes ( 10 , 11 ). (frontiersin.org)
Recessive1
  • Neoplasm found in domesticated plants occurs as a result of mutation, and a smooth pod without neoplasm is governed by a recessive 'np' gene, while neoplasm is controlled by a single dominant gene 'Np' [14, 15] . (researchgate.net)
Body3
  • The circulating system is vital for nutrient delivery across the body. (biomedcentral.com)
  • Human body works like a perfect machine with an automated gear system. (yes4homeopathy.com)
  • When a bacteria or virus attacks, our body defends with physiological changes (production of certain already present antibacterial agents secreted by it on the cell wall or producing free fluid in large quantity so that the bacteria or virus is washed off or die its own death by changing the biochemistry temporarily), as a result there is irritation, inflammation or oversensitivity. (yes4homeopathy.com)
Disorders1
  • The field of inherited disorders of the nervous system has undergone major revolutions in the past 150 years. (medscape.com)
Occur1
  • Which physiological changes can occur because of a vitamin deficiency? (thesisrush.com)
Interactions1
  • Systems for co-incubation and co-culture have been created to enable research on the interactions between acinar cells and inflammatory or stellate cells. (gbmn.org)
Nervous1
  • In fact-in one of the most detailed examples of rapid evolution to date-a new study shows that just one cold snap can change the way green anoles' muscular and nervous systems respond to temperature. (uncommondescent.com)
Mechanisms1
Diabetes1
  • We conclude that V reduces gene expression of hepcidin in diabetic rats, improving the anemic state caused by diabetes. (repositoriosalud.es)
Cells3
  • For example, cancer cells preferentially perform glycolysis in the cytosol even in the presence of oxygen, a phenomenon that is known as the "Warburg effect" or "aerobic glycolysis. (frontiersin.org)
  • Warburg and Szent-Gyorgyi, in thinking about cancer, emphasized that growth is the primordial function of all cells, and that the differentiated functions of complex organisms involve restraints of that primitive function, imposed by a system that has developed through time. (raypeat.com)
  • The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. (lookformedical.com)
Conditions2
  • elatius, all F 1 plants had neoplastic pods, and the F 2 populations segregated in a good fit ratio of 3 (neoplasm): 1 (free from neoplasm) under glasshouse conditions, which suggests that neoplasm on pods of the tall wild pea was controlled by a single dominant gene. (researchgate.net)
  • Under hypoxic conditions, hypoxia-inducible factor-2α (HIF-2α) plays a pivotal role in upregulating the expression of genes involved in iron absorption, such as divalent metal transporter 1 (DMT1) and ferroportin (Fpn) 11 . (nature.com)
Cluster1
  • In humans, they are encoded in a gene cluster on CHROMSOME 16. (nih.gov)
Environmental2
  • SIGNAL TRANSDUCTION: EVOLUTION OF AN IDEA Nobel Lecture, December 8, 1994 by MARTIN RODBELL National Institute of Environmental Health Scienes, P.O. Box 12933, Research Triangle Park, North Carolina, USA In general there is no set of observations conceivable which can give enough information about the past of a system to give com- plete information as to its future. (nih.gov)
  • As part of its mission, BER invests in crosscutting technologies and programs to enable multiscale, systems-level research to achieve a predictive understanding of systems biology, biological community function, and environmental behavior. (energy.gov)
Expression2
  • Their function is still not fully understood, but they are thought to regulate gene expression by sequestrating proteins or mRNAs with inverted repeats in their 3′ UTRs. (wikipedia.org)
  • However, the function of NEAT1 and Paraspeckles is not always positive, it has been proven that they enhance the malignancy and stemness of breast tumours by increasing the expression of the WNT4 gene. (wikipedia.org)
Muscular1
  • What's the significance of myosin in the muscular system? (thesisrush.com)
Response1
  • This phenomenon is called the fight-or-flight response, and it's an evolutionary advancement that developed to help you survive when your life is at risk. (globalhealing.com)
Dietary1
  • DRI - Dietary Risk Index, a system that quantifies relative pesticide dietary risk from ingestion of a known quantity of food (usually a typical serving as set by USDA ) during a given day. (hh-ra.org)
Cell3
  • This phenomenon is demonstrated during the cell cycle. (wikipedia.org)
  • Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. (lookformedical.com)
  • After the limits of reversible physiological changes are crossed, certain changes take place in the genes, which include irreversible changes in the morphology or the structure of the cell. (yes4homeopathy.com)
Biology3
  • BER supports fundamental research to understand the systems biology of plants and microbes through the GSP. (energy.gov)
  • Systems biology-driven approaches will build on the understanding of these processes to design new pathways and tools for biofuels and bioproducts. (energy.gov)
  • This subtopic specifically targeted systems biology-driven basic research for the production of advanced biofuels (i.e., biologically synthesized compounds with the potential to serve as energy dense transportation fuels such as gasoline, diesel, and aviation fuel) compatible with existing engines and fuel distribution infrastructure, and for the production of useful bioproducts. (energy.gov)
Found1
  • As copper acts as an essential micronutrient at low doses but can produce free radicals and damage DNA in excess, the mediation of copper often involves a complex system of regulators, chaperones, and transporters that are commonly found conserved across a wide range of species. (biomedcentral.com)
Complex1
  • Second Messenger Systems: cardiomyopathies in which an hypoxic etiology is triggered in blood to an weak regional context acid as a repair or complex. (worldclassbows.com)
Responsible2
  • The overall results suggest that some activating mechanism for the progeny virus of wild-type Sendai virus exists in the lung of mice and the principle (activator) responsible for this phenomenon has a character similar to trypsin. (nih.gov)
  • ERS - Economic Research Service, the USDA agency responsible for studying the economic performance, costs and benefits, and policy issues impacting U.S. agriculture and the food system. (hh-ra.org)
Issues1
  • Millions of people struggle with digestive issues every day, and in many cases, the root cause is an unhealthy gut. (vitanetonline.com)
Understand1
  • We developed fluid-flow and static test systems based on purified mucin polymers, the major gel-forming constituents of the mucus barrier, to understand how the mucus barrier influences bacterial virulence, particularly the integrity of Pseudomonas aeruginosa biofilms, which can become resistant to immune clearance and antimicrobial agents. (nih.gov)
Mouth1
  • Animals re- ceive their nourishment through a mouth, into an internal digestive or alimentary canal. (nih.gov)