• cells
  • In vitro evaluation showed good cell adherence and proliferation of bone marrow derived mesenchymal stem cells seeded on covalently crosslinked alginate dialdehyde-gelatin (ADA-GEL) hydrogel films with and without 0.1% nano-Bioglass ® (nBG). (mdpi.com)
  • This biomaterial is also seeded with B cells. (cryonics.org)
  • Biomaterial treatment has been shown to enhance survival, improve function, promote proliferation, and guide the mobilization and recruitment of different cells in the post-MI heart. (frontiersin.org)
  • This review will provide a summary on the biomaterials developed to enhance cardiac regeneration and remodeling post-MI with a focus on how they control macrophages, cardiomyocytes, fibroblasts, and endothelial cells. (frontiersin.org)
  • Adhesion of cells could only be observed in the presence of gelatin. (artificial-organs.com)
  • Osteochondral defect repair using bilayered hydrogels encapsulating both chondrogenically and osteogenically pre-differentiated mesenchymal stem cells in a rabbit model," Osteoarthritis and Cartilage , vol. 22, no. 9, pp. 1291-1300, 2014. (hindawi.com)
  • Microencapsulation of cells by using biodegradable hydrogels offers numerous attractive features for a variety of biomedical applications including tissue engineering. (rsc.org)
  • The exciting concept of stem cells, their applications in tissue healing, and the role biomaterials play in controlling stem cell behavior is also discussed. (rochester.edu)
  • The main objective of these technologies is to produce high-throughput and/or customized organ substitutes (or bioartificial organs) with heterogeneous cell types or stem cells along with other biomaterials that are able to repair, replace or restore the defect/failure counterparts. (mdpi.com)
  • Cells and therapeutic molecules can be included in the initial hydrogel precursor solution, and processed into 3D constructs. (engineering.org.cn)
  • Doris Taylor's heart in a jar Tissue-engineered airway Tissue-engineered vessels Artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bioprinted constructs for battlefield burn repairs. (wikipedia.org)
  • stiffness
  • Increase in the ratio of thiol-modified gelatin reduced gel stiffness by diluting the effective concentration of the HA component. (wiley.com)
  • Using widely available materials, the module helps teachers lead students through an investigation of how the stiffness of tissues in the body vary based on their function, and about the importance of matching biomaterial and host tissue stiffness. (rochester.edu)
  • vivo
  • In addition, the viability and adhesion of neonatal rat cardiomyocytes (NRCM) seeded onto the hydrogels was examined by in vivo imaging of NRCM-mediated scaffold contraction as well as by histological evaluation after immunostaining. (artificial-organs.com)
  • injectable
  • Hydrogel MPs are incorporated into the injectable paste, they swell during mixing and injection to retain water in the pores, and instead of leaching out, the porogens create pores as they can degrade in physiological condition. (pubmedcentralcanada.ca)
  • Alginates
  • Extensive work has been done using alginates which are regarded as the most suitable biomaterials for cell microencapsulation due to their abundance, excellent biocompatibility and biodegradability properties. (wikipedia.org)
  • poly
  • Singh B, Sharma V (2017) Crosslinking of poly(vinylpyrrolidone)/acrylic acid with tragacanth gum for hydrogels formation for use in drug delivery applications. (springer.com)
  • ionic
  • Unlike the thermoplastics that are often utilized in traditional 3D printing, the chain entanglements and ionic interactions within the hydrogel-like bioink rather than temperature dominate shape fidelity. (wikipedia.org)
  • proteins
  • These hydrogels encompass light-sensitive naturally-derived proteins, shear-thinning biomaterial gels, and surgical sealants, each of which has opened new horizons for tissue engineering, minimally invasive medical procedures, and advanced biomedicine. (wikipedia.org)
  • Many biopolymers - proteins, carbohydrates, glycoproteins, and mucopolysaccharides - may be used to form hydrogels that contribute to temporary adhesion. (wikipedia.org)
  • biomedical
  • Tissue Engineering and Biomaterials Laboratory, Departments of Orthopedic Surgery and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota. (pubmedcentralcanada.ca)
  • NFC hydrogel in 3D cell culture offers a platform for various biomedical applications. (wikipedia.org)
  • The chapter hopes that the module will be adopted by middle school science teachers, and that it will help encourage student engagement in science at the middle school level, and help increase widespread understanding of the field of biomaterials and biomedical engineering. (rochester.edu)
  • Khademhosseini has further expanded his contribution in the field of biomedical adhesives by developing an elastic and adhesive hydrogels for surgical applications. (wikipedia.org)
  • shear
  • A second class of hydrogels pioneered by the group is a nanosilicate-based shear thinning gel that could be easily injected in a minimally invasive medical procedure. (wikipedia.org)
  • Biomimetic
  • Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma. (annals.org)
  • fabrication
  • Recently, photo-fabrication has also been explored to dynamically modulate hydrogel features in real time, providing enhanced control of cell fate and delivery of bioactive compounds. (engineering.org.cn)
  • shape fidelity
  • Important considerations in printability include: Uniformity in filament diameter Angles at the interaction of filaments "Bleeding" of filaments together at intersects Maintenance of shape fidelity after printing but before cross-linking Printing pressure and nozzle diameter Alginate is a naturally derived biopolymer from the cell wall of brown algae that has been widely used as a biomaterial. (wikipedia.org)
  • Transparent crosslinked ultrashort peptide hydrogel dressing with high shape-fidelity accelerates healing of full-thickness excision wounds" (PDF). (wikipedia.org)
  • mechanical properties
  • The state of the art of the physical/chemical crosslinking methods of the gelatin-based hydrogels being used to overcome the weak mechanical properties is highlighted. (mdpi.com)
  • We tune the mechanical properties of the hydrogel using the chitin nanofiber content and show proof-of-concept applications in engineering vascular tissues. (rsc.org)
  • natural
  • Differences from traditional 3D printing materials Printed at a much lower temperature (37 °C or below) Mild cross-linking conditions Natural derivation Bioactive Cell manipulatable Bioink compositions and chemistries are often inspired and derived from existing hydrogel biomaterials. (wikipedia.org)
  • properties
  • This allows investigation into the relationship between the rate of drug diffusion and hydrogel properties such as mesh size. (rochester.edu)
  • In recent years BC itself and in combination have become the subject of intensive studies for the synthesis of hydrogels in search of properties and applications of BC-based hydrogels. (springer.com)
  • On the whole, the review after introducing BC production and its properties discusses the synthesis of BC-based smart hydrogels with various composite materials, formation mechanism, and improved characters. (springer.com)
  • form
  • In current study, we propose a novel concept of using hydrogel microparticles (MPs) as porogens to reproducibly form well-interconnected pore networks. (pubmedcentralcanada.ca)
  • cell
  • Current research in tissue engineering is geared towards elucidating the appropriate compositional elements (biomaterials, biomolecules and cell sources) as well as methods of assembly. (biomedcentral.com)
  • To address this, biomaterial therapy is being investigated as an approach to improve regeneration in the infarcted heart, as they can possess the potential to control cell function in the infarct environment and limit the adverse compensatory changes that occur post-MI. (frontiersin.org)
  • and various effects have been observed on different cell types depending on the biomaterial that is applied. (frontiersin.org)
  • A better understanding of how a biomaterial interacts with the different cell types in the heart may lead to the development of a more optimized biomaterial therapy for cardiac regeneration. (frontiersin.org)
  • GrowDex is NFC hydrogel for 3D cell culture commercialized by UPM, Finland. (wikipedia.org)
  • ratio
  • The swelling ratio of ADA-GEL microcapsules of all compositions was significantly decreased, whereas the degradability was found to increase with the increase of gelatin ratio. (rsc.org)