G. vaginalis is a facultatively anaerobic Gram-variable rod that is involved, together with many other bacteria, mostly anaerobic, in bacterial vaginosis in some women as a result of a disruption in the normal vaginal microflora. (wikipedia.org)
G. vaginalis is not considered the cause of the bacterial vaginosis, but a signal organism of the altered microbial ecology associated with overgrowth of many bacterial species. (wikipedia.org)
Although G. vaginalis is a major species present in bacterial vaginosis, it can also be isolated from women without any signs or symptoms of infection. (wikipedia.org)
Bacterial vaginosis is commonly treated with antibiotics such as metronidazole or clindamycin, which works by targeting G.vaginalis. (wikipedia.org)
G. vaginalis is associated with bacterial vaginosis, which may be asymptomatic, or may have symptoms including vaginal discharge, vaginal irritation, and a "fish-like" odor. (wikipedia.org)
Although there is definite association of colonisation of the endometrium by mycoplasma and ureaplasma in patients with bacterial vaginosis, as we showed in our previous study, this study did not show any association of DUB with bacterial vaginosis, Gardnerella vaginalis , mycoplasma, or ureaplasma. (bmj.com)
This allows G. vaginalis to proliferate, causing Bacterial Vaginosis , or BV which is the most common vaginal infection in females of reproductive age. (osmosis.org)
Gardnerella vaginalis is a gram-variable coccobacillus, non-motile and facultative anaerobic bacterium, known to cause bacterial vaginosis (BV). (osmosis.org)
Gardnerella vaginalis isn't a disease itself , but it plays a role in the development of a condition called bacterial vaginosis (BV). (stdwatch.com)
Anyone who has a vagina can get bacterial vaginosis caused by a Gardnerella vaginalis overgrowth. (stdwatch.com)
Despite the fact that G. vaginalis can be found in practically all women's vaginal microbiota, untreated bacterial vaginosis can still lead to serious long-term health complications. (stdwatch.com)
Standard methodology for the susceptibility testing of the potential bacterial vaginosis pathogens, Gardnerella vaginalis, Mobiluncus spp. (theodora.com)
Gram's stain results consistent with a diagnosis of bacterial vaginosis include (a) markedly reduced or absent Lactobacillus morphology, (b) predominance of Gardnerella morphotype, and (c) absent or few white blood cells. (theodora.com)
The present study was conducted to correlate the biotypes of Gardnerella vaginalis strains isolated from cases of bacterial vaginosis and their virulence factors. (manipal.edu)
Thirty-two strains of G. vaginalis isolated from cases of bacterial vaginosis were biotyped. (manipal.edu)
Udayalaxmi, J , Bhat, GK & Kotigadde, S 2011, ' Biotypes and virulence factors of Gardnerella vaginalis isolated from cases of bacterial vaginosis ', Indian Journal of Medical Microbiology , vol. 29, no. 2, pp. 165-168. (manipal.edu)
Bacterial vaginosis (BV) is a condition of having too much of the gardnerella vaginalis bacterium present. (wku.edu)
Nugent scores that are based on weighted tallies of various cellular morphotypes (most notably lactobacilli, Gardnerella vaginalis , Bacteroides , as well as curved Gram-variable rod-shaped bacteria) are also widely used in the diagnosis of bacterial vaginosis. (news-medical.net)
Trichomonas3
This and other tests can be used to distinguish between vaginal symptoms related to G. vaginalis and those caused by other organisms, such as Trichomonas and Candida albicans, which are similar and may require different treatment. (wikipedia.org)
Trichomonas vaginalis, Chlamydia trachomatis , N. gonorrhoeae, Candida albicans, and Herpes simplex virus should be ruled out. (theodora.com)
What is more, along with G. vaginalis, a number of other anaerobic bacteria species can proliferate, like Mobiluncus, Bacteroides or Prevotella which are also present in low numbers in normal vaginal flora - resulting in a mixed infection. (osmosis.org)
These produce hydrogen peroxide which tend to inhibit the growth of other types of more harmful bacteria especially varieties such as Gardnerella vaginalis, Mobiluncus, Mycoplasma and Bacteroides. (home-remedies-for-you.com)
Other organisms implicated in the pathogenesis of PID include Neisseria gonorrhoeae , Gardnerella vaginalis , Haemophilus influenzae , and anaerobes such as Peptococcus and Bacteroides species. (medscape.com)
Prevotella2
In this study, we established a BV model in which we coinfected mice with G. vaginalis and another species commonly found in women with BV: Prevotella bivia. (wustl.edu)
Generally, this condition is characterized by a shift in microbial composition from an abundance of lactobacilli in healthy women, to an increase of commensal anaerobic bacteria (such as Gardnerella , Atopobium , Prevotella and a panoply of other species). (news-medical.net)
Haemophilus1
Haemophilus vaginalis vaginitis: a newly defined specific infection previously classified 'nonspecific' vaginitis. (intramed.net)
Atopobium2
Clindamycin had greater activity against Atopobium vaginae, Gardnerella vaginalis and Mobiluncus spp. (nih.gov)
Orally applied metronidazole significantly reduced Shannon diversity and the mean relative abundance of Gardnerella vaginalis , Atopobium vaginae , and Sneathia amnii , while L. iners increased to levels twofold higher than those found in healthy women. (biomedcentral.com)
Bacteria5
Gardnerella vaginalis is a species of Gram-variable-staining facultative anaerobic bacteria. (wikipedia.org)
Gardnerella reveals a classic "clue cell" under the microscope, showing bacteria adhering to the surface of squamous epithelial cells. (wikipedia.org)
So, Gram-variable bacteria, like G. vaginalis, first appear Gram-positive and then, as the culture ages, they gradually lose the peptidoglycan in their wall, and once their wall is too thin to retain purple color , they become Gram-negative. (osmosis.org)
The words "Gardnerella vaginalis" may not sound familiar to you, but this tiny bacteria plays an important role in the maintenance of female reproductive health. (stdwatch.com)
Gardnerella vaginalis is a type of bacteria that is normally part of the vaginal microbiota or microbiome (VMB). (stdwatch.com)
Candida5
Diagnostic Value of DNA Hybridization Test for Gardnerella vaginalis, Candida spp. (cumhuriyet.edu.tr)
Objective: The aim of this study was to determine the efficiency of DNA hybridization in women with vaginal discharge evaluated by conventional laboratory methods including wet mount, whiff test, and Gram stain used in combination for the diagnosis of Gardnerella vaginalis, Candida spp. (cumhuriyet.edu.tr)
Conventional laboratory methods detected combined Gardnerella and Candida infections in 2 (3.2%) patients, whereas 1 (1.6%) patient was positive for both infections by DNA hybridization test. (cumhuriyet.edu.tr)
Two (3.2%) patients were identified with T vaginalis by conventional laboratory methods and 1 (1.6%) by DNA hybridization test who incidently was also positive for G. vaginalis and Candida. (cumhuriyet.edu.tr)
Abnormal vaginal flora was found in 4.8% of cases, Candida albicans in 1.2%, Tri- chomonas vaginalis in 0.9% and actinomycosis in 1 case. (who.int)
Gram-variable2
Gardnerella vaginalis , or G. Vaginalis for short, is a gram-variable coccobacillus present in low numbers in normal vaginal flora. (osmosis.org)
Now, G. vaginalis is gram-variable, which means it can stain either positive or negative with Gram-staining. (osmosis.org)
Pathogens1
Boric acid has been shown to be effective against BV, due to its ability to remove BV-specific biofilms and enhance eradication of G.vaginalis and other potential bacterial pathogens, resulting in reduced recurrence of symptomatic BV. (wikipedia.org)
Vaginal flora1
Gardnerella vaginalis on its own won't necessarily cause any symptoms, since it's part of your normal vaginal flora. (stdwatch.com)
Causative1
G. vaginalis was identified as the causative organism in 11 (17.5%) patients by conventional laboratory methods and in 5 (7.9%) patients by DNA hybridization test. (cumhuriyet.edu.tr)
Infection4
A variety of diagnosis techniques are currently available for identifying Gardnerella Vaginalis such as the OSOM BV Blue assay, FemExam cards and nucleic acid amplification tests (NAATs), resulting in the determination of an ongoing BV infection. (wikipedia.org)
Gardnerella can cause bacterial vaginosa, an infection of the vagina in a woman. (nanobugs.com)
Gardnerella can cause a bloodstream infection in a mother after the delivery of a baby and possibly in the baby, too. (nanobugs.com)
It is notable that G. vaginalis facilitated uterine infection by P. bivia. (wustl.edu)
Vaginosis1
Due to its similarity in symptomatic nature with other vaginal afflictions like yeast infections and Trichmonas vaginalis, lab tests have to be conducted to confirm the presence of vaginosis. (home-remedies-for-you.com)
Clinical1
Gardnerella vaginalis: characteristics, clinical considerations, and controversies. (intramed.net)
Virulence3
Now, when vaginal pH increases, G. vaginalis can use a number of virulence factors to cause disease. (osmosis.org)
We did not find any statistical correlation between G. vaginalis biotypes and its virulence factors. (manipal.edu)
Virulence factors expressed by G. vaginalis were not associated with a single biotype. (manipal.edu)
Reproductive1
However, an overgrowth of G. vaginalis can also cause female health problems, such as infections of the reproductive tract. (stdwatch.com)
Vaginolysin2
citation needed] G. vaginalis produces a pore-forming toxin, vaginolysin, which affects only human cells. (wikipedia.org)
Ok, now, G. vaginalis produces a cytotoxin called vaginolysin and an enzyme called sialidase, and both of these help it adhere to the vaginal epithelial cells and colonize the vaginal epithelium. (osmosis.org)
Facultative1
Finally, G. vaginalis is non-spore forming, non-motile and facultative anaerobic which means it can survive in both aerobic and anaerobic environments. (osmosis.org)
Produces1
Then, G. vaginalis produces proteolytic carboxylase enzymes which will break down vaginal peptides into volatile amines, which have an unpleasant smell. (osmosis.org)
Disease1
G. vaginalis isn't considered to be the main cause of the disease, though. (stdwatch.com)
Enzyme1
Protease and sialidase enzyme activities frequently accompany G. vaginalis. (wikipedia.org)
Organism1
Finally, the nucleic acid amplification tests (NAATs), such as PCR, are commonly used detection techniques due to its ability of detecting as little as one organism in a sample, providing a closer look to Gardnerella Vaginalis and BV status. (wikipedia.org)
Symptoms1
Gardnerella Vaginalis has been originally discovered in 1953 by Sidney Leopold as a nonmotile, nonencapsulated, pleomorphic gram-negative rod from the vaginas of women who showed symptoms of cervicitis. (wikipedia.org)
Metronidazole1
Identification of intrinsically metronidazole-resistant clades of Gardnerella vaginalis. (cdc.gov)
Methods1
Methods: We previously demonstrated that Gardnerella vaginalis could elicit many BV features in mice. (wustl.edu)
Activity1
FemExam, besides detecting vaginal fluid pH and trimethylamine presence, is able to measure proline iminopeptidase activity of G.Vaginalis. (wikipedia.org)