• Sequence
  • In the absence of sequence similarity, the SMPI structure shows clear similarity to both domains of the eye lens crystallins, both domains of the calcium sensor protein-S, as well as the single-domain yeast killer toxin. (wikipedia.org)
  • homology
  • Interestingly and perhaps excitingly from an evolutionary perspective, some crystallins are active enzymes, while others lack activity but show homology to other enzymes. (wikipedia.org)