• tubules
  • Capillaries in the walls of the tubules reabsorb the water and the salts required by the body and deliver them to a system of small kidney veins which, in turn, carry them into the renal vein and return them to the general circulation. (thefreedictionary.com)
  • The salt-conserving operation appears to be a primary function of the renal tubules which encapsulate the glomerulus. (encognitive.com)
  • This makes sense with our ongoing theme of organogenesis starting with a bunch of tubes but it also makes perfect sense when we think ahead to the adult kidney being a series of tubules and ducts. (blogspot.com)
  • To me the development of the series of tubes and tubules of the kidney can be thought of as growing vines, spreading out in different directions, some dying off at certain points while others are thriving, and some adding on more complex anatomical structure as they mature and grow. (blogspot.com)
  • This first pair of primitive kidneys are orientated on the head to tail axes and as they grow downward they induce more caudally located intermediate mesoderm to produce the second set of primitive tubules, these are the mesonephric tubules of the mesonephros . (blogspot.com)
  • arterioles
  • To determine the underlying cellular mechanism, experiments were performed on freshly isolated preglomerular resistance arterioles obtained from kidneys of 7-week-old spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY). (ahajournals.org)
  • embryonic
  • These appear in succession during embryonic development, but only the metanephros persists in the adult. (encognitive.com)
  • Present in all embryonic life, it is exhibited differentially in adults. (encognitive.com)
  • Embryonic stem (ES) cells, with their ability to generate all, or nearly all, of the cell types in the adult body and a possible source of cells genetically identical to the donor, hold great promise but face ethical and political hurdles for human use. (aspetjournals.org)
  • Recall that everyone has a pair of kidneys, and thus at the earliest stage of kidney development we start with an embryonic pair of kidneys. (blogspot.com)
  • The earliest form of kidneys represent another transient/embryonic structure like some others we have encountered and are called the pronephros. (blogspot.com)
  • By the time the mesonephros comes about the first pair of embryonic kidneys, the pronephros, start to degenerate. (blogspot.com)
  • Pluripotent embryonic stem cells are highly proliferative, capable of differentiating into all cells of the kidney, and respond to tissue-specific extracellular matrix proteins. (ufl.edu)
  • functions
  • Despite its relative simplicity, the zebrafish kidney develops and functions in almost the same way as humans. (jove.com)
  • The kidney also functions in maintaining proper homeostasis in the body, maintaining balance of water content and electrolyte composition, as well as blood pressure and volume. (blogspot.com)
  • fluid
  • Over 150 liters of fluid enter the glomeruli of an adult every day: 99% of the water in that filtrate is reabsorbed. (wikipedia.org)
  • Via one or more of these mechanisms, the kidney participates in the control of the volume of various body fluid compartments, fluid osmolality, acid-base balance, various electrolyte concentrations, and removal of toxins. (wikipedia.org)
  • When the kidney is damaged, it cannot get rid of wastes and extra fluid in the body. (jollyga.com)
  • Creatinine
  • Creatinine is transported through the bloodstream to the kidneys.High Creatinine Levels usually is an indicator of kidney dysfunction for c. (blogspot.com)
  • We hope that this technique of measuring GFR is useful to other investigators studying mouse kidney function and will replace less accurate methods of estimating kidney function, such as plasma creatinine and blood urea nitrogen. (jove.com)
  • Mice sacrificed 24 hr following surgery demonstrate loss of renal function with elevation of the serum or plasma creatinine level as well as structural kidney damage with acute tubular necrosis evident. (jove.com)
  • Creatinine clearance rate (CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. (wikipedia.org)
  • However, blood urea nitrogen (BUN) and creatinine will not be raised above the normal range until 60% of total kidney function is lost. (wikipedia.org)
  • wastes
  • The kidneys function to regulate the volume, composition, and pH of body fluids and remove metabolic wastes from the blood in the process. (slideserve.com)
  • function
  • Renal physiology is the study of kidney function. (wikipedia.org)
  • ACE inhibitors, a type of blood pressure medicine, preserve kidney function in patients with diabetes. (wikipedia.org)
  • 2. Repair the damaged kidneys and restore the renal function. (blogspot.com)
  • Micro-Chinese Medicine is a kind of Chinese herbal treatment which can block further decline of kidney function and provide a favorable environment for kidney repair. (blogspot.com)
  • With this treatment, we can protect the residual renal function units and restore the damaged kidney function. (blogspot.com)
  • Kidneys serve the general function of maintaining the chemical and physical constancy of blood and other body fluids. (encognitive.com)
  • However, a major draw back has been the difficulty in evaluating zebrafish kidney function after genetic manipulation. (jove.com)
  • We describe a fluorescent assay that utilizes the optical transparency of the zebrafish to quantitatively monitor the clearance of a fluorescent dye, over time, from the vasculature and out through the kidney, to give a read out of renal function 1,6-9 . (jove.com)
  • As this protein is strongly conserved, this is evidence of abnormal kidney function. (wikipedia.org)
  • The results of these tests are used to assess the excretory function of the kidneys. (wikipedia.org)
  • liver
  • The asymmetry within the abdominal cavity, caused by the position of the liver, typically results in the right kidney being slightly lower and smaller than the left, and being placed slightly more to the middle than the left kidney. (wikipedia.org)
  • The right kidney sits just below the diaphragm and posterior to the liver. (wikipedia.org)
  • The superior pole of the right kidney is adjacent to the liver. (wikipedia.org)
  • regulate
  • The kidneys also help control the rate of red blood cell formation by secreting erythropoietin, and regulate blood pressure by secreting renin. (slideserve.com)
  • organs
  • Week 7- Highlights- Kidney, lung and other organs began development, external genitals start to develop, eyelids form, bone development begins. (blogspot.com)
  • Ok let's talk kidney development, to be honest and geeky, the kidney is one of my favorite organs in terms of anatomy and physiology. (blogspot.com)
  • Ideally, the resulting extracellular matrices would retain the organ-specific architecture and chemical composition to guide implanted cells into functional structures and eventually working organs. (ufl.edu)
  • cilia
  • Similar devices are found in fresh-water invertebrates where water may be pumped out either as the result of work done by the heart, contractile vacuoles, or cilia found in such specialized "kidneys" as flame bulbs, solenocytes, or nephridia that extract excess water from the body cavity rather than from the circulatory system. (encognitive.com)
  • acute
  • Renal ischaemia reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) in patients and occlusion of renal blood flow is unavoidable during renal transplantation. (jove.com)
  • In hospitalized patients, over 50% of cases of acute kidney injury (AKI) are caused by renal ischemia 1-3 . (jove.com)
  • metanephric
  • The metanephric kidneys of reptiles lie in the posterior part of the abdominal cavity, usually in the pelvic region. (encognitive.com)
  • A rather typical mammalian metanephric kidney (Fig. 1) is a compact, bean-shaped organ attached to the dorsal body wall outside the peritoneum. (encognitive.com)
  • Once the ureteric bud is made, it then interacts with the final precursor cells, the metanephric mesoderm to form the final pair of kidneys, which as you can probably guess go by the name of metanephros. (blogspot.com)
  • extracellular
  • Examining the ability of these cells to proliferate and differentiate in a whole kidney extracellular matrix scaffold would serve as a valuable baseline for future studies in producing a functioning organ. (ufl.edu)
  • renin
  • A class of drugs used to decrease hypertension, mainly by interfering with the renin kidney-blood pressure control cycle. (wikipedia.org)
  • An agent which interferes with the renin (kidney-lung-heart blood pressure control) cycle. (wikipedia.org)
  • parenchyma
  • a progressive disease characterized by formation of multiple cysts of varying size scattered diffusely throughout both kidneys, resulting in compression and destruction of renal parenchyma, usually with hypertension, gross hematuria, and uremia leading to progressive renal failure. (thefreedictionary.com)