• individuals
  • A. fumigatus is the most frequent cause of invasive fungal infection in immunosuppressed individuals, which include patients receiving immunosuppressive therapy for autoimmune or neoplastic disease, organ transplant recipients, and AIDS patients. (wikipedia.org)
  • A. fumigatus primarily causes invasive infection in the lung and represents a major cause of morbidity and mortality in these individuals. (wikipedia.org)
  • However, in healthy individuals the innate immune system is an efficacious barrier to A. fumigatus infection. (wikipedia.org)
  • produce
  • A. fumigatus grown on certain building materials can produce genotoxic and cytotoxic mycotoxins, such as gliotoxin. (wikipedia.org)
  • The term is applied particularly to distinguish heterothallic fungi, which require two compatible partners to produce sexual spores, from homothallic ones, which are capable of sexual reproduction from a single organism. (wikipedia.org)