Effects of D-psicose on diet-induced obesity are not clearly elucidated, and we investigated food intake, body weight, and fat accumulation in rats fed high-fat (HF) diet. (nih.gov)
This effect was more prominent in D-psicose-fed rats with normal diet than with HF diet, suggesting combination of psicose and calorie restriction further reduced obesity. (nih.gov)
High-fructose corn syrup causes characteristic of obesity in rats: Increased body weight, body fat and triglyceride levels. (oliveridley.org)
The diet-induced obesity model (DIO model) is an animal model used to study obesity using animals that have obesity caused by being fed high-fat or high-density diets. (wikipedia.org)
Lakhan S, Kirchgessner A (2013) The emerging role of dietary fructose in obesity and cognitive decline. (springer.com)
Download Research Study PDF Objective To test the hypothesis that that the ingestion of glucose and fructose may differentially stimulate GLP-1 and insulin response in lean adolescents and adolescents with obesity. (fructosefacts.org)
In a commentary featured in the April issue of Diabetes Care, researchers Kahn and Sievenpiper argue that blaming sugar, and specifically fructose, on the obesity and diabetes epidemics is misguided. (fructosefacts.org)
has concluded that the current evidence does not link the consumption of fructose and fructose-containing sugars with the global obesity epidemic. (fructosefacts.org)
Fructose is not likely a contributor to the obesity epidemic in the U.S., according to the results of a recent study. (fructosefacts.org)
The review article, "The emerging role of dietary fructose in obesity and cognitive decline" by Lakhan and Kirchgessner has serious limitations. (fructosefacts.org)
Sucrose7
Sprague-Dawley rats became obese by feeding HF diet for 4 wk, and were assigned either to normal or HF diet supplemented with or without D-psicose, sucrose, or erythritol for 8 wk. (nih.gov)
D-psicose-fed rats exhibited lower weight gain, food efficiency ratio, and fat accumulation than erythritol- and sucrose-fed rats. (nih.gov)
These rats gained more weight on HFCS compared to a sucrose (regular sugar) diet even though they were fed the same calories. (oliveridley.org)
In Experiment 1, male Sprague-Dawley rats were maintained for short term (8 weeks) on (1) 12 h/day of 8% HFCS, (2) 12 h/day 10% sucrose, (3) 24 h/day HFCS, all with ad libitum rodent chow, or (4) ad libitum chow alone. (oliveridley.org)
Rats with 12-h access to HFCS gained significantly more body weight than animals given equal access to 10% sucrose, even though they consumed the same number of total calories, but fewer calories from HFCS than sucrose. (oliveridley.org)
The male house flies produced less elimination spots/h when fed with trypticase soy broth than with the two sucrose solutions. (oaji.net)
Hepatic steatosis3
In the present study, a high-fructose diet fed rat model of hypertriglyceridemia, dyslipidemia, insulin resistance and hepatic steatosis was employed to investigate the global transcriptional changes in the lipid metabolizing pathways in three insulin sensitive tissues: liver, skeletal muscle and adipose tissue in response to chronic dietary administration of NDGA. (biomedcentral.com)
The MEFT protected the rats against hepatic steatosis and inflammation but fenofibrate protected against hepatic microsteatosis. (sysrevpharm.org)
Dekker MJ, Su Q, Baker C, Rutledge AC, Adeli K (2010) Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome. (springer.com)
Ingestion2
2017). Natural mineral-rich water ingestion by ovariectomized fructose-fed Sprague-Dawley rats: Effects on sirtuin 1 and glucocorticoid signaling pathways . (up.pt)
Download Research Study PDF Objective To present the hypothesis that hepatic glycogen stores may regulate metabolic responses to fructose ingestion and could therefore be a target to prevent or mitigate the negative metabolic effects of fructose intake. (fructosefacts.org)
Consumption7
2008). Chronic green tea consumption decreases body mass, induces aromatase expression, and changes proliferation and apoptosis in adult male rat adipose tissue . (up.pt)
Does regular consumption of green tea influence expression of vascular endothelial growth factor and its receptor in aged rat erectile tissue? (up.pt)
The role of fructose in NAFLD (steatosis) pathogenesis has received a great deal of attention in part because from 1999 to 2004 the consumption of fructose increased by ~32 % [ 36 ]. (biomedcentral.com)
In conclusion, cognitive deficits induced by chronic liquid fructose consumption are not exclusively related to increased caloric intake and are correlated with hypertriglyceridemia, impaired insulin signaling, increased oxidative stress and altered mitochondrial dynamics, especially in the frontal cortex. (springer.com)
A new study, published in the American Journal of Clinical Nutrition, reports that consumption of beverages sweetened with glucose, fructose, or high-fructose corn syrup (HCFS) do not promote inflammation or gut permeability. (fructosefacts.org)
Potential therapeutic activity of mango (mangifera indica L.) leaves on excess consumption of fructose in rats. (jceionline.org)
Chow1
Sprague-Dawley male rats (SD) were fed a chow (control) diet, high-fructose diet (HFrD) or HFrD supplemented with NDGA (2.5 g/kg diet) for eight weeks. (biomedcentral.com)
Differentially1
Schaefer EJ, Gleason JA, Dansinger ML (2009) Dietary fructose and glucose differentially affect lipid and glucose homeostasis1-3. (springer.com)
Male7
Over the course of 6 or 7 months, both male and female rats with access to HFCS gained significantly more body weight than control groups. (oliveridley.org)
Sixteen male Sprague-Dawley rats 6-8 weeks old received left testis 720° torsion for 3 h followed by detorsion with or without MSCs. (biomedcentral.com)
showed an anti-inflammatory activity in an acute inflammation model of VCO using in vivo models (Male Balb-C and Sprague-Dawley rats). (485587.com)
Here, we examined in male rats whether acute exposure (7-9 days) to HFD during juvenility [from postnatal day (PND) 21 to PND 28-30] or adulthood (from PND 60 to PND 67-69) is sufficient to affect hippocampal functions and whether it is also dependent on GRs activation. (nature.com)
There was a noticeable difference in the body weight (BW) of male and female diabetic rats. (jceionline.org)
The lipid levels and BW of male and female rats were examined at consistent periods throughout the research. (jceionline.org)
EEMS exhibited a noteworthy antihyperlipidemic actions in addition with marked difference on BW of both male and female in alloxan-induced diabetic rats. (jceionline.org)
Dietary2
MEFT can d as prxis against dietary fructose-induced elements of MD but caution musaken as low dose MEFT increases hepatic lipid acc in females predisposing to fatty liver disease. (sysrevpharm.org)
Campos VC, Tappy L (2016) Physiological handling of dietary fructose-containing sugars: implications for health. (springer.com)
Intake2
Various preclinical studies have investigated the effect of CBD on feeding behaviour in rodents [58, 93, 155,159,195], with results suggesting that higher doses may influence food intake several hours post-treatment. (researchgate.net)
Wistar rats) [155], failed to influence food intake during a 1 h ad libitum feeding period, moderate to high doses of CBD (4.4 mg·kg −1 , i.p. [58]. (researchgate.net)
Methods1
Methods: Transient ischemia was induced by 90 mins middle-cerebral artery occlusion (MCAO) in Sprague-Dawley rats, and LITA or control liposomes given intraperitoneally at occlusion and daily for up to two weeks post-MCAO. (westminster.ac.uk)
Glucose4
D-Psicose, a C-3 epimer of D-fructose, has shown promise in reducing body fat accumulation in normal rats and plasma glucose level in genetic diabetic mice. (nih.gov)
This study investigated the activity of the HPA axis in selected markers of glucose handling, and the stress response relative to components of the HPA axis in a diet-induced pre-diabetic rat model. (researchsquare.com)
We supplemented Sprague-Dawley female rats with 10% w / v fructose in drinking water or with isocaloric glucose solution for 7 months. (springer.com)
Stanhope KL, Schwarz JM, Keim NL et al (2009) Consuming fructose-sweetened, not glucose-sweetened, beverages increase visceral adiposity and lipids and decrease insulin sensitivity in overweight/obese men. (springer.com)
Diabetic5
Sprague Dawley Rats were randomly divided into non-prediabetic group (NPD) and pre-diabetic group (PD) (n=6, per group) over a 20-week induction period and a further 12-week experimental period to get 32 weeks. (researchsquare.com)
All told, these results indicate that a moderately high fat diet of coconut oil, either in the presence or absence of fructose, does not induce significant diabetic symptoms while isocaloric diets with soybean oil do. (485587.com)
To investigate effect on BW and the antihyperlipidemic actions of ethanolic extract of mango seed (EEMS) on alloxan-mediated diabetic Sprague-Dawley rats. (jceionline.org)
Parasuraman S, Ching TH, Leong CH, Banik U. Antidiabetic and antihyperlipidemic effects of a methanolic extract of Mimosa pudica (Fabaceae) in diabetic rats. (jceionline.org)
Antioxidative effect of phenolic extract of vitex doniana leaves on alloxan-induced diabetic stress and histological changes in the pancreas of Wistar Rat. (jceionline.org)
Nutrition1
1 Its significance in human nutrition was realized when taurine level was found to be below the normal range in the plasma and urine of preterm formula-fed infants. (jomes.org)
2016). Characterization of TGF-β expression and signaling profile in the adipose tissue of rats fed with high-fat and energy-restricted diets . (up.pt)
Induction2
In the Long Evans Cinnamon rats, induction of hepatic AR expression was shown to be associated with the development of hepatitis and hepatoma [ 10 ]. (hindawi.com)
One day after induction of Thy 1.1 glomerulonephritis, rats were treated with increasing doses of the Ang I converting enzyme (ACE) inhibitor enalapril and/or the Ang II receptor blocker losartan in the drinking water. (scienceopen.com)
Diets3
Ficus thonningii extracts exhibit hypoglycaemic, hypolipidaemic and antioxidant activitiese investigated the potential of methanolic F. thonningii stem-bark extracts (MEFT) to protect growing Sprague-Dawley (SD) against high-fructose diet-induced Metabolic Derangements (MD) in a model mimicking childreenic diets. (sysrevpharm.org)
Lowette K, Roosen L, Tack J, Van den Berghe P (2015) Effects of high-fructose diets on central appetite signaling and cognitive function. (springer.com)
As a growing medium used in bacterial transmission experiments, undiluted trypticase soy broth was used to feed 3-day-old females and males of Musca domestica following two different diets upon emergence and the frequency of elimination spots was estimated. (oaji.net)
Caloric1
High-fructose corn syrup (HFCS) accounts for as much as 40% of caloric sweeteners used in the United States. (oliveridley.org)
Dyslipidemia1
To study the effect of mango seeds on dyslipidemia in diabetes-induced rats. (jceionline.org)
Hypertension1
Collectively, we demonstrate the functional impact of p66Shc within the cerebral circulation and demonstrate that the genetic background of p66Shc rats largely drives changes in cerebrovascular function.NEW & NOTEWORTHY We demonstrate that the modulation of p66Shc signaling impairs cerebral artery myogenic tone in a low renin model of hypertension. (bvsalud.org)
Diabetes2
Diabetes was induced in pregnant rats by a single dose of streptozotocin (STZ, 50 mg/kg ip) in late gestation. (bvsalud.org)
Antidiabetic effects of Mangifera indica Kernel Flour‐supplemented diet in streptozotocin‐induced type 2 diabetes in rats. (jceionline.org)
Diet3
Hepatocyte Growth Factor (HGF) expression in high-fat diet fed rat corpus cavernosum. (up.pt)
Counter intuitively, our results also suggest that the addition of fructose to the diet may even protect against the IR caused by soybean oil. (485587.com)
Feeding the flies a sugar liquid diet resulted in producing more fecal spots than regurgitation spots. (oaji.net)
Mice1
Carbamazepine has demonstrated anticonvulsant properties in rats and mice with electrically and chemically induced seizures. (nih.gov)
Effect2
The effect of p66Shc gain or loss of function in nonhypertensive rats is unclear. (bvsalud.org)
Edokwe C. Cardioprotective effect of methanolic extract of magnifera indica (mango) seed flour on acetaminophen-induced cardiotoxicity in Albino Rats. (jceionline.org)
Commonly1
This well designed and well executed study provides rather conclusive proof that High Fructose Corn Syrup , the sweetener most commonly used in North America, makes you gain weight in a way not explained by calories alone. (oliveridley.org)
Significantly1
For instance, in rats fed with fructose, hepatic AR is significantly upregulated, which is associated with impaired activation of Stat3 and suppressed activity of PPAR α in the liver [ 9 ]. (hindawi.com)
Genetic1
This impairment is dependent upon the genetic background, as modulated p66Shc signaling in Sprague-Dawley rats does not impair cerebral artery myogenic tone. (bvsalud.org)
In females, MEFT prevented fructose- induced plasma triglyceride increase. (sysrevpharm.org)
Expression1
Fructose supplementation reduced the expression of antioxidant enzymes and altered the amount of proteins involved in mitochondrial fusion/fission in the frontal cortex. (springer.com)