• Unlike stable or unstable angina, no pathological plaque or deposition is present within the coronary arteries that elicits the presentation. (medscape.com)
  • Unstable angina occurs unexpectedly and usually at rest or lasts longer than stable angina. (deansilvermd.com)
  • Variant angina, also called Prinzmetal's angina, is a form of unstable angina caused by coronary artery spasm. (deansilvermd.com)
  • Unstable angina is considered an emergency and it may be a harbinger of acute myocardial infarction or sudden death. (deansilvermd.com)
  • Unstable angina - is characterized by sudden pain that doesn't go away on its own or respond to rest or medication. (rxharun.com)
  • This is a specific form of unstable angina that can occur at any time (no trigger event causes it to happen). (rxharun.com)
  • Stable angina is less serious than unstable angina, but it can be very painful or uncomfortable. (rxharun.com)
  • The almost-exclusive cause of ACS, including unstable angina, acute myocardial infarction (AMI) with or without ST-segment elevation, and sudden cardiac death, is atherothrombosis. (ecrjournal.com)
  • I assume the researchers did not include acute myocardial infarctions (heart attacks) and unstable angina . (vayafail.com)
  • Unstable angina, CHF needing oxygen supplement. (dentalcare.com)
  • Prinzmetal angina or variant angina occurs as a result of transient coronary artery spasms. (medscape.com)
  • Heart disease as a first-degree atrioventricular block or the Prinzmetal angina. (medizzine.com)
  • Stable angina is usually predictable, occurs in situations that increase myocardial oxygen demand such as exercise or stress and is relieved by rest or sublingual nitroglycerin. (deansilvermd.com)
  • Medications used to treat angina include sublingual nitroglycerin for acute attacks, beta blockers and calcium channel blockers. (deansilvermd.com)
  • Results of well designed, placebo-controlled, short-term studies demonstrate that add-on therapy with ranolazine ER in patients with chronic stable angina improves exercise performance, and reduces anginal frequency and nitroglycerin use. (wustl.edu)
  • Patients should be asked about the frequency of angina, severity of pain, and number of nitroglycerin pills used during episodes. (medscape.com)
  • Because myocardial oxygen demand is determined mainly by heart rate, systolic wall tension, and contractility, narrowing of a coronary artery typically results in angina that occurs during exertion and is relieved by rest. (msdmanuals.com)
  • Dantonic , the drug has been shown to have few adverse side effects and to effectively reduce the frequency of chronic stable angina - a form of chest pain that most often occurs with activity or emotional stress and causes the heart to need more oxygen. (taslyus.com)
  • Angina decubitus - Is angina that occurs spontaneously during rest. (rxharun.com)
  • UA is suggested by angina pain that occurs for the first time and is then experienced with increasing frequency or that is a known symptom of previously diagnosed stable angina which is rapidly worsening (over days - in less than 2 weeks). (unboundmedicine.com)
  • Moat common type of angina usually occurs while doing some activity and exerting stress and relief by medications. (furqanali.com)
  • With the progression of angina duration, severity and frequency increases. (vsebolezni.com)
  • The severity of angina is often graded on a 4-point scale with Functional Class IV being the most severe. (deansilvermd.com)
  • There was an improvement of exercise capacity in patients with stable angina and decreased frequency and severity. (deansilvermd.com)
  • Alcohol consumption has been shown to induce anginal attacks in a large proportion of patients with variant angina with a lag time of 1.5 to 18 hours and to decrease exercise tolerance in patients with stable exertional angina. (deansilvermd.com)
  • Alcohol-induced variant angina may also be aggravated by magnesium deficiency, which is common in heavy alcohol users. (deansilvermd.com)
  • Variant angina - is caused by a spasm in a coronary artery, causing it to temporarily narrow. (rxharun.com)
  • This property increases myocardial oxygen delivery in patients with coronary artery spasm,and is responsible for the effectiveness of nifedipine in vasospastic (Prinzmetal's or variant) angina. (nih.gov)
  • Nifedipine is indicated for the management of vasospastic angina confirmed by any of the following criteria: 1) classical pattern of angina at rest accompanied by ST segment elevation, 2) angina or coronary artery spasm provoked by ergonovine, or 3) angiographically demonstrated coronary artery spasm. (rxlist.com)
  • In those patients who have had angiography , the presence of significant fixed obstructive disease is not incompatible with the diagnosis of vasospastic angina, provided that the above criteria are satisfied. (rxlist.com)
  • Nifedipine may also be used where the clinical presentation suggests a possible vasospastic component but where vasospasm has not been confirmed, e.g., where pain has a variable threshold on exertion or when angina is refractory to nitrates and/or adequate doses of beta blockers . (rxlist.com)
  • In a double-blind trial, supplementation with Q10 decreased the frequency of anginal episodes and increased exercise tolerance compared with placebo in patients with stable angina. (deansilvermd.com)
  • Tedisamil also decreased (in a dose dependent way) the frequency of anginal attacks and the consumption of short acting nitrates, an improvement that became significant for all doses in the second treatment week. (bmj.com)
  • Study shows that it reduces the frequency of anginal events. (indi-shop.com)
  • All segments of clinically significant stenosis in the coronary arteries of 54 men with stable angina were categorised according to the position of the plaques (eccentric or concentric) and the presence or absence of a pool of extracellular lipid. (bmj.com)
  • Microvascular angina is a diagnosis of dysplasia, which is made when the angina is accompanied by an abnormal exercise test, normal coronary arteries and the absence of inducible coronary artery spasm. (deansilvermd.com)
  • Symptoms of angina occur when the coronary arteries are narrowed or blocked by atherosclerosis or by a blood clot. (rxharun.com)
  • This suggests that, in general, relief of spasm or dilation of coronary arteries is not an important factor in classical angina. (nih.gov)
  • Nifedipine is indicated for the management of chronic stable angina (effort-associated angina) without evidence of vasospasm in patients who remain symptomatic despite adequate doses of beta blockers and/or organic nitrates or who cannot tolerate those agents. (rxlist.com)
  • In chronic stable angina (effort-associated angina) nifedipine has been effective in controlled trials of up to eight weeks duration in reducing angina frequency and increasing exercise tolerance, but confirmation of sustained effectiveness and evaluation of long-term safety in these patients are incomplete. (rxlist.com)
  • Controlled studies in small numbers of patients suggest concomitant use of nifedipine and beta-blocking agents may be beneficial in patients with chronic stable angina, but available information is not sufficient to predict with confidence the effects of concurrent treatment, especially in patients with compromised left ventricular function or cardiac conduction abnormalities. (rxlist.com)
  • 191 patients) Monotherapy Assessment of Ranolazine In Stable Angina trial was a dose-response study that showed increasing doses of razonaline increased exercise duration by 94, 103 and 116 seconds. (escardio.org)
  • Patients treated with ranolazine had significantly better exercise duration - an ncrease by 115 seconds from baseline versus 91 seconds in placebo group - time to onset of angina, and fewer angina attacks. (escardio.org)
  • This finding suggests that patients who experience postprandial angina could benefit from consuming small frequent meals as opposed to larger less frequent meals. (deansilvermd.com)
  • Patients with angina should be advised to avoid alcohol or limit its intake not to provoke an attack. (deansilvermd.com)
  • Several studies have found that magnesium deficiency is common in patients with angina. (deansilvermd.com)
  • In some case reports, administration of a series of magnesium injections resulted in complete resolution or marked improvement in some patients with angina. (deansilvermd.com)
  • Oral magnesium supplementation was also found in a double-blind trial to be of some benefit to patients with angina. (deansilvermd.com)
  • In clinical trials, supplementation with quinitine improved exercise tolerance in patients with stable angina. (deansilvermd.com)
  • OBJECTIVE To determine the efficacy and safety of the potassium channel blocker tedisamil versus placebo in the treatment of patients with stable angina. (bmj.com)
  • Aim: to reveal the frequency of clopidogrel resistance in patients with acute coronary syndrome (ACS) and its impact on prognosis in these patients. (ter-arkhiv.ru)
  • Thus, ranolazine ER is a useful new option for patients with chronic stable angina whose symptoms are not controlled with first-line antianginal therapy or who do not tolerate first-line antianginal agents. (wustl.edu)
  • Further evidence supporting conservative management for most patients with stable coronary artery disease (CAD) and angina comes from a new study of more than 30,000 patients in the prospective CLARIFY registry. (mental-fitness-group.com)
  • At 5 years, 33.9% of these patients still had angina symptoms, 12.3% had had a myocardial infarction (MI) or undergone revascularization, 8.0% had died, but 45.8% were event-free and angina-free. (mental-fitness-group.com)
  • Patients whose angina resolved at 1 year with conservative management were not at higher risk for the composite primary outcome of cardiovascular death or nonfatal MI than those who never experienced angina, but had a higher risk for MI. (mental-fitness-group.com)
  • As reported July 15 in Circulation, the CLARIFY registry involved 32,691 patients (mean age, 64.2 years) with stable CAD enrolled between November 2009 and June 2010. (mental-fitness-group.com)
  • Over 5-year follow-up, angina regressed in 7773 patients - most (84.4%) without a new medical intervention. (mental-fitness-group.com)
  • and it's partly related to the somewhat surprising finding in this study that many of these patients had resolution of angina with just medical therapy," he said. (mental-fitness-group.com)
  • The authors write that it also "shows that medical treatment and disease-modifying interventions may take some time to be effective and relieve symptoms, and the relatively low event rate of patients with stable CAD allows a period of watchful waiting before failure of medical management is declared. (mental-fitness-group.com)
  • The finding that 33.9% of patients with baseline angina still had angina symptoms at 5 years, they note, reflects an "unmet need for new more effective antianginal therapy. (mental-fitness-group.com)
  • The mainstays of angina treatment are b-blockers, CCBs, and nitrates and for prevention of cardiovascular events in these patients include ACE inhibitors, ARBs, thiazide and thiazide-like diuretics, b-blockers (particularly after MI), CCBs, antiplatelet drugs, and drugs for the treatment of dyslipidemia. (medicaldialogues.in)
  • The development of methods to enhance care for patients with chronic stable angina is ongoing. (ijtpr.com)
  • When combined to regular antianginal medication, nicorandil significantly reduced the frequency of ischemia episodes in coronary heart disease (CHD) patients with stable angina. (ijtpr.com)
  • Current ACC/AHA guidelines recommend that in patients with stable angina, noninvasive testing is used to prove mild or moderate ischaemia prior to performing PCI. (bmj.com)
  • Among patients referred for invasive coronary angiography (ICA) because of stable chest pain and intermediate pretest probability of coronary artery disease, the risk of major adverse cardiovascular events was similar in the CT group and the ICA group. (vayafail.com)
  • Sensitivity, specificity and predictive values of linear and nonlinear indices of heart rate variability in stable angina patients. (imed.pub)
  • ABSTRACT To determine frequency of cardiovascular risk factors in Saudi and non-Saudi diabetics, we studied patients attending King Abdulaziz University Hospital for follow-up in the period January 1997 to December 2001. (who.int)
  • Don't perform neuroimaging studies in patients with stable headaches that meet criteria for migraine. (medscape.com)
  • A recent publication has shown that cardiac troponin T (TnT) concentrations measured with a highly sensitive assay were significantly associated with the incidence of cardiovascular death and heart failure in stable coronary artery disease after adjustment for other independent prognostic indicators [ 13 ]. (hindawi.com)
  • Low frequency power of heart rate variability reflects baroreflex function, not cardiac sympathetic innervation. (imed.pub)
  • The most common cause of angina is impaired blood flow secondary to coronary atherosclerosis. (deansilvermd.com)
  • In such cases, angina can result whether atherosclerosis is present or not. (msdmanuals.com)
  • A decreased oxygen supply, as in severe anemia or hypoxia, can precipitate or aggravate angina. (msdmanuals.com)
  • If angina is not relieved, unmet myocardial oxygen demand increases further, making MI more likely. (rxharun.com)
  • Whether this effect plays any role in classical angina is not clear, but studies of exercise tolerance have not shown an increase in the maximum exercise rate-pressure product, a widely accepted measure of oxygen utilization. (nih.gov)
  • This unloading of the heart reduces myocardial energy consumption and oxygen requirements and probably accounts for the effectiveness of nifedipine in chronic stable angina. (nih.gov)
  • Approximately 9.8 million Americans are estimated to experience angina annually, with 500,000 new cases of angina occurring every year. (medscape.com)
  • [ 1 ] The first description of angina as a medical disorder came from William Heberden. (medscape.com)
  • 1 Another description of angina states that it is a "discomfort in the chest or adjacent areas caused by myocardial ischemia. (rxharun.com)
  • Thus, more people have angina in the morning, when arterial tone is relatively high. (msdmanuals.com)
  • The study at hand asks which is a better way to image heart arteries in a patient with stable chest pain: CT versus standard arterial angiography . (vayafail.com)
  • Due to the peculiarities of the dosage form, a constant concentration of Metoprolol in the plasma is maintained and a stable clinical effect of the drug is maintained for 24 hours. (bestpharmbuy.com)
  • Add-on Trimetazidine is a fast-acting, low-risk method of lowering both angina episodes and nitrate use in the real-world clinical environment. (ijtpr.com)
  • The major clinical characteristic of angina is chest pain. (rxharun.com)
  • Since the heart treated with atenolol beat slowly and with less force, it uses lesser energy thus relieving pain in angina and also reduces the risk of heart attack. (medindia.net)
  • is clinically worsening angina (eg, angina at rest or with increasing frequency and/or intensity of episodes). (msdmanuals.com)
  • The results of the current research indicate that adjunctive therapy is an effective and safe method of lowering the frequency of angina episodes and the need for nitrates. (ijtpr.com)
  • Stable angina - is characterized by regular episodes of pain triggered by physical exercise or activity, smoking, eating large meals, or extreme temperatures. (rxharun.com)
  • Only 4.5% of angina was controlled by coronary revascularization and 11.1% with increases or changes in antianginal medications. (mental-fitness-group.com)
  • Increase in frequency, duration, and intensity over a very small amount of stress. (furqanali.com)
  • Morphological characteristics of clinically significant coronary artery stenosis in stable angina. (bmj.com)
  • Angina may also occur on the background of other serious ailments and allergic or infectious lesions. (vsebolezni.com)
  • Nocturnal angina - May occur if a dream causes striking changes in respiration, pulse rate, and BP. (rxharun.com)
  • Overall attacks of angina and the use of short acting nitrates were assessed from patient diaries. (bmj.com)
  • The frequency of angina resolution in the first year, Steg said, suggests the need to lengthen the 1- to 4-week blanking period frequently used in trials testing treatments for angina, including revascularization. (mental-fitness-group.com)
  • In addition, evidence suggests that therapy for angina should be tailored to each individual patient, their comorbidities, and the underlying cause of their condition. (ijtpr.com)
  • Nocturnal angina may also be a sign of recurrent LV failure, an equivalent of nocturnal dyspnea. (rxharun.com)
  • walk, but there was a nonsignificant atopilot toward increased improvement in NYHA class in the treated group as compared to placebo (15 vs. Methyl pelargonate.Gueudin, M. 43 MHz subcarrier frequency from the chrominance section to act as a stable clocktiming reference for motor speed control. (forextrading-madeeasy.com)
  • In a number of cases reported in which attacks of angina were triggered by reactive hypoglycemia, in these cases blood sugar drops too low. (deansilvermd.com)
  • The disease is known as angina, the symptoms and treatment of which we will explore in more detail. (vsebolezni.com)
  • Stable angina, the main symptoms and treatment of which we will describe below, is divided into four functional classes. (vsebolezni.com)
  • Beta-blockers (BBs) and calcium channel blockers (CCBs) are the drugs of choice for initial treatment of stable angina, with other classes of drugs used in case the first two are insufficient. (ijtpr.com)
  • National recommendations about diagnostics and treatment of stable stenocardia. (kazanmedjournal.ru)
  • For example, if the patient answered yes to asthma, further information about causes, frequency, date of hospitalization if any, and medications should be obtained and noted. (dentalcare.com)
  • In stable angina, the relationship between workload or demand and ischemia is usually relatively predictable. (msdmanuals.com)
  • Dietary intake data was obtained through a 169-item food frequency questionnaire. (uib.no)
  • SAQ, Seattle Angina Questionnaire. (jamanetwork.com)