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Tuberculosis complexNontuberculous mycobacteriumOrganismBacteriaAbstractFortuitumTargeting Mycobacterium tuberculosisInfectionsPathogensChelonaeAbscessusSmegmatisBovisAvium-intracellulareParatuberculosisBacteriumDermatologic manifestationsStrainComplexGenusTaxonomyMarinum infectionPulmonary tuberculosisAtypicalCausative agentATCCPolymerase Chain ReMycobacterialOpportunistic pathogenH37RvBiosynthesisMacrophagesPathogenicSkin and soft-tissueSpecies levelPeer reviewMacrolidesPatientsBeijingBacterialSoilRespiratorySymptomsEvadeTransmissionClassificationCattleTuberculose
Tuberculosis complex6
  • In August 2013, the Food and Drug Administration (FDA) permitted marketing of the Xpert MTB/RIF assay (Cepheid, Sunnyvale, California) to detect DNA of the Mycobacterium tuberculosis complex (MTBC) and genetic mutations associated with resistance to rifampin (RMP) in unprocessed sputum and concentrated sputum sediments ( 1 ). (cdc.gov)
  • Among six samples with positive results in culture, one was identified by PCR-RFLP as belonging to the M. tuberculosis complex and one was identified as a non-tuberculosis mycobacteria. (scielo.br)
  • Of the 120 isolates analysed, 118 (98.3%) were identified as M. tuberculosis complex and 2 (1.7%) were identified as mycobacteria other than M. tuberculosis. (who.int)
  • The results showed that those 2 isolates were multi-drug resistant and the DNA sequencing analysis showed that the alignment of nucleic acid of DNA in isolates of mycobacteria other than M. tuberculosis was different from that of M. tuberculosis complex. (who.int)
  • Mycobacterial species isolated from sputum and grown in culture were examined to distinguish between NTM and the Mycobacterium tuberculosis complex (MTBC). (who.int)
  • Apart from the Mycobacterium tuberculosis complex (MTBC), the genus Mycobacterium includes over 120 species of non-tuberculous mycobacteria (NTM). (who.int)
Nontuberculous mycobacterium2
  • Mycobacterium fortuitum is a rapidly growing nontuberculous mycobacterium (NTM), classified in the Runyon group IV. (medscape.com)
  • Mycobacterium marinum is a nontuberculous mycobacterium capable of causing skin and soft tissue infections. (cdlib.org)
Organism6
Bacteria9
  • We also look for problems with unusual bacteria or fungi, and in the course of looking for fungi, we also found the nontuberculous mycobacteria. (cdc.gov)
  • Mycobacterium gastri is a species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium. (wikipedia.org)
  • Sputum stain for mycobacteria is a test to check for a type of bacteria that cause tuberculosis and other infections. (medlineplus.gov)
  • Seven lineages of Mycobacterium tuberculosis (MTB), the bacteria that causes "Tuberculosis" (TB), have been identified till date [ 1 ]. (hindawi.com)
  • Mycobacterium tuberculosis (MTB) and Mycobacterium avium complex (MAC) are two distinct types of bacteria that can cause infections in the lungs and other parts of the body. (medicalnewstoday.com)
  • Also, MAC bacteria are environmental organisms commonly found in soil, dust, water sources, and in domestic and wild animals. (medicalnewstoday.com)
  • Similarly, doctors often find MAC infections challenging to treat due to the inherent resistance of the bacteria to many commonly used antibiotics. (medicalnewstoday.com)
  • However, finding bacteria in stools is normal and doesn't necessarily mean there's a problem. (healthy.net)
  • The cell walls of pathogenic and acidophilic bacteria , such as Mycobacterium tuberculosis and Mycobacterium leprae , contain lipoarabinomannan and arabinogalactan. (bvsalud.org)
Abstract1
Fortuitum1
  • It is important to keep in mind that other outbreaks of nontuberculous mycobacteria have been associated with tattoo parlors, and in follow-up to this investigation, other outbreaks in other tattoo parlors in other states identified a variety of nontuberculous mycobacteria, including M fortuitum, M chelonae , and M abscessus . (medscape.com)
Targeting Mycobacterium tuberculosis1
Infections3
  • Medical tourists have developed chronic NTM infections (particularly rapidly growing mycobacteria) of surgical sites, breast prostheses, and injection sites. (medscape.com)
  • This is an important outbreak that raises our concern about the potential for such nontuberculous mycobacteria infections associated with tattooing. (medscape.com)
  • Cite this: Mycobacteria Infections Associated With Tattooing - Medscape - Sep 27, 2012. (medscape.com)
Pathogens4
  • Coenzyme A (CoA) is a fundamental co-factor for all life, involved in numerous metabolic pathways and cellular processes, and its biosynthetic pathway has raised substantial interest as a drug target against multiple pathogens including Mycobacterium tuberculosis . (nature.com)
  • The most commonly encountered mycobacterium pathogens, however, are species of MAC. (wcponline.com)
  • Mycobacterium avium complex (MAC) is the most common of the pathogens and can cause several different patterns of abnormalities [ 1 , 2 ]. (ajronline.org)
  • Mycobacteria other than Mycobacterium tuberculosis can be human pathogens, and the incidence of infection appears to be increasing. (msdmanuals.com)
Chelonae2
Abscessus3
  • Just found out I have mycobacterium abscessus! (mayoclinic.org)
  • It is a great reminder of what my ID doc says 'Mycobacteria is slow to grow and slow to go' - this is generally true of MAC, abscessus, even TB - which is why, in addition to antibiotic resistance, it is so difficult to treat. (mayoclinic.org)
  • Mycobacterium avium complex (MAC)-the closely related species of M. avium and M. intracellulare -accounts for most NTM disease, but M. abscessus is increasingly becoming common. (msdmanuals.com)
Smegmatis1
Bovis2
Avium-intracellulare4
  • This article reviews the dermatologic manifestations of Mycobacterium avium-intracellulare (MAI, or MAC) infection. (medscape.com)
  • See also Mycobacterium Avium-Intracellulare . (medscape.com)
  • In the United States, Mycobacterium avium-intracellulare (MAI, or MAC) infection is considered a nonreportable infectious disease. (medscape.com)
  • It is important to consider cutaneous infection with Mycobacterium avium-intracellulare (MAI, or MAC) in patients with antibiotic-resistant cellulitis, nonhealing nodules, and ulcers, as well as in patients who are immunosuppressed with evidence of disseminated MAI (DMAI) infection. (medscape.com)
Paratuberculosis4
Bacterium2
Dermatologic manifestations1
  • For additional information on cutaneous M marinum infection, see the Medscape Reference article Dermatologic Manifestations of Mycobacterium Marinum Infection of the Skin. (medscape.com)
Strain2
  • Notably, it was also found that KRM had a markedly larger MIC (0.25 microgram/ml) for MAC N-444 within A-549 cells than its MIC (0.008 microgram/ml) for the same strain residing in MM6-M phi s. (nih.gov)
  • Using geographic information system and molecular tools, we characterized a possible outbreak of tuberculosis caused by Mycobacterium tuberculosis Beijing strain in 17 patients in Cotonou, Benin, during July 2005-October 2006. (cdc.gov)
Complex3
Genus1
Taxonomy1
  • Click through the PLOS taxonomy to find articles in your field. (plos.org)
Marinum infection3
Pulmonary tuberculosis2
Atypical3
  • To this spectrum of pulmonary diseases caused by atypical mycobacteria, a new granulomatous disease process that has been referred to as "hot tub lung" has been described in the literature [ 11 - 13 ]. (ajronline.org)
  • Mycobacterium marinum is an atypical Mycobacterium species found in cold or warm, fresh or salted water. (medscape.com)
  • M marinum is water-borne atypical Mycobacterium species that commonly infects fish and amphibians. (medscape.com)
Causative agent1
ATCC1
  • For living cultures, ATCC lists the media formulation and reagents that have been found to be effective for the product. (atcc.org)
Polymerase Chain Re1
  • Some investigators have found evidence of MTb in tissues using the polymerase chain reaction (PCR) to amplify mycobacterial DNA or rRNA 6-8 but more recent studies have failed to identify such organisms in the majority of tissue samples from patients with sarcoidosis. (bmj.com)
Mycobacterial2
Opportunistic pathogen1
  • Mycobacterium shigaense is a novel, slow-growing, scotochromogenic mycobacterium ( 1 ), initially reported in 2012 as an opportunistic pathogen isolated from skin biopsy samples from a patient with a history of Hodgkin disease and severe cellular immunodeficiency. (cdc.gov)
H37Rv1
Biosynthesis1
  • While prevalent in mycobacteria, markers of F(420) biosynthesis appeared to be absent from the normal human gut flora. (umd.edu)
Macrophages4
  • Mycobacterium tuberculosis (MTB) has successfully exploited macrophages as its primary niche in vivo, but the bacterial genome-wide requirements that promote its intracellular survival remain undefined. (harvard.edu)
  • In one example, phosphate transport, requiring physically unlinked genes, was found to be critical for MTB growth in macrophages and important for establishing persistent infection in lungs. (harvard.edu)
  • Remarkably, the majority of MTB genes found by this analysis to be required for survival are constitutively expressed rather than regulated by macrophages, revealing the host-adapted lifestyle of an evolutionarily selected intracellular pathogen. (harvard.edu)
  • Notably, we found that a subset of MBAs were active against Mycobacterium tuberculosis both in vitro and in macrophages. (nature.com)
Pathogenic1
Skin and soft-tissue1
Species level1
Peer review1
Macrolides1
  • The organisms were found to be susceptible to both macrolides and doxycycline , and the patients were treated with either one or both of those agents. (medscape.com)
Patients8
  • Wellington S. Tichenor] First of all, it's very difficult to find in many patients. (cdc.gov)
  • We've found that we had to do many cultures in patients with sinusitis in order to find it. (cdc.gov)
  • The first involved finding the nontuberculous mycobacteria and treating the patients. (cdc.gov)
  • However, MAI has been found to cause cutaneous disease in individuals mostly with immunosuppression, although it has also been reported in immunocompetent patients as well. (medscape.com)
  • RESULTS MTb DNA was not detected in any of the tissue samples from patients with sarcoidosis or other respiratory disease but was found in all four patients with tuberculosis. (bmj.com)
  • MAP was found in the blood of patients with Crohn's disease but not in healthy people. (abc.net.au)
  • Mycobacterium farcinogenes - senegalense group infection should be considered as a potential pathogen of skin infection in immunocompetent patients. (biomedcentral.com)
  • Cross-reactivity between a streptococcal 60- to 65-kd heat shock protein (hsp) and the oral mucosa has been demonstrated, and significantly elevated levels of serum antibodies to hsp are found in patients with RAS. (medscape.com)
Beijing2
Bacterial2
  • In contrast, the MAC consists of several related bacterial species, including Mycobacterium avium ( M. avium ) and Mycobacterium intracellulare ( M.intracellulare ), which are widespread in the environment. (medicalnewstoday.com)
  • Tuberculous meningitis , also known as TB meningitis or tubercular meningitis , is a specific type of bacterial meningitis caused by the Mycobacterium tuberculosis infection of the meninges -the system of membranes which envelop the central nervous system . (wikipedia.org)
Soil4
  • Also found in soil. (wikipedia.org)
  • It is distributed worldwide and is found in soil and water. (medscape.com)
  • MAC organisms are commonly found in bird droppings, soil and natural waters, including marine waters, lakes, rivers, streams, ponds and springs, and are frequently isolated from water distribution systems (piped waters). (wcponline.com)
  • 1 NTM can be found in the environment, including water and soil, which is the suspected source of occasional infection of humans. (who.int)
Respiratory1
  • Not surprisingly, some studies have found that compared to non-healthcare settings, healthcare personnel could be at a higher risk of exposure to infectious respiratory diseases. (cdc.gov)
Symptoms1
  • Septic arthritis is a challenging clinical problem because (1) signs and symptoms may be subtle and overlap with those found in other conditions, (2) screening laboratory studies and synovial fluid cultures are relatively insensitive, and (3) optimal management, including duration of antibiotics and surgical approach, is not evidence based. (medscape.com)
Evade1
  • The unique glycan structures of mycobacteria contribute to their ability to evade mammalian immune responses . (bvsalud.org)
Transmission1
Classification1
  • Classification and identification of mycobacteria. (wikipedia.org)
Cattle1
Tuberculose1
  • No presente trabalho, o método de detecção de Mycobacterium tuberculosis pela Reação em Cadeia da Polimerase (PCR) em amostras de escarro foi padronizado e o diagnóstico laboratorial da tuberculose pulmonar foi avaliado, comparando-se as metodologias de baciloscopia, cultura e PCR. (scielo.br)