• nystatin
  • It offers an intriguing possibility for difficult-to-treat systemic infections, such as invasive aspergillosis, or infections that demonstrate resistance to amphotericin B. Cryptococcus is also sensitive to nystatin. (wikipedia.org)
  • The oral suspension form produces a number of adverse effects including but not limited to: Diarrhea Abdominal pain Rarely, tachycardia, bronchospasm, facial swelling, muscle aches Both the oral suspension and the topical form can cause: Hypersensitivity reactions, including Stevens-Johnson syndrome in some cases Rash, itching, burning and acute generalized exanthematous pustulosis Like amphotericin B and natamycin, nystatin binds to ergosterol, a major component of the fungal cell membrane. (wikipedia.org)
  • therapy
  • A case report indicated that voriconazole in combination with amphotericin B as salvage therapy for disseminated coccidioidomycosis was successful. (wikipedia.org)
  • drug
  • Torrado-Santiago, S. "Amphotericin B formulations and drug targeting" Journal of Pharmaceutical Sciences 2008, volume 97, pp. 2405-2425. (wikipedia.org)
  • Dr.Atal also initiated the bioenhanced anti tubercular drug research project using Rifampicin which later resulted in development of world's first bioenhanced anti tubercular drug formulation. (wikipedia.org)
  • posed major
  • The amphipathic nature of amphotericin along with its low solubility and permeability has posed major hurdles for oral administration given its low bioavailability. (wikipedia.org)