AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaHumanitiesInformation ScienceNamed GroupsHealth CareGeographicals
BlindnessNight BlindnessBlindness, CorticalVision, LowOnchocerciasis, OcularCataractVisually Impaired PersonsXerophthalmiaTrachomaEye Diseases, HereditaryVisual AcuityEye DiseasesVision DisordersGlaucomaCataract ExtractionRefractive ErrorsVitamin A DeficiencyEye InjuriesElectroretinographyMacular DegenerationCorneal DiseasesNepalPrevalenceColor Vision DefectsOnchocerca volvulusOptic AtrophyRetinaRetinal DiseasesOphthalmologyCorneal OpacityDiabetic RetinopathyRetinal DegenerationRetinitis PigmentosaGenetic Diseases, X-LinkedIndiaOnchocerciasisAmaurosis FugaxEye ProteinsKeratitisAge DistributionDark AdaptationGlaucoma, Open-AngleAphakiaLeber Congenital AmaurosisRetinopathy of PrematurityNigeriaRetinal Rod Photoreceptor CellsTrichiasisRural HealthEducation, SpecialVision, Ocularcis-trans-IsomerasesCartoons as TopicSex DistributionEducation of Visually DisabledPhotoreceptor Cells, VertebratePedigreeVision ScreeningMyopiaUveitisEyeglassesRhodopsinOmanFundus OculiVitamin ASensory AidsTongaVision TestsOnchocercaWorld HealthHealth SurveysField Dependence-IndependenceSudanColor Perception Tests
River BlindnessBlue-yellow coChildhood blindnessPrevent blindnessFace BlindnessNight blindnessCause blindnessMacular degenerationColor vision defPreventable blindnessControl of blindnessGeneticOccursCAUSES BLINDNESSComplete blindnessCongenital blindnessPrevalenceSightAchromatopsiaInabilityVaried during the progPreventionCataractDonateCommonColorsPeopleGenesGene therapyBilateralDiseasesEliminateVision lossSymptomsOphthalmologyManuscriptDeficiencyTreatmentProblemsRareRetinaTypeTypicallyCureSevere formWidelyMutationVisualCondition
River Blindness19
  • Merck (NYSE:MRK), known as MSD outside the United States and Canada, commends the government of Guatemala on being the fourth country in Latin America to receive World Health Organization (WHO) verification of the elimination of river blindness (onchocerciasis). (merck.com)
  • With this verification, four of the six countries in the Americas historically at-risk for river blindness have verified elimination of the disease. (merck.com)
  • River blindness is a debilitating disease that affects individuals and their families, as well as the larger health care system and the economy," said Kenneth C. Frazier, chairman and chief executive officer of Merck. (merck.com)
  • Until river blindness is entirely eliminated around the world, we remain committed to working with our partners in the fight against this preventable disease. (merck.com)
  • In October 1987, Merck announced it would donate the medication MECTIZAN to all who need it for as long as necessary until river blindness is eliminated as a public health problem. (merck.com)
  • The MECTIZAN Donation Program reaches more than 100 million people annually for river blindness. (merck.com)
  • The Drugs for Neglected Diseases initiative (DND i ) has been awarded $29.2 million to accelerate the development of innovative new drugs for patients in sub-Saharan Africa with sleeping sickness (human African trypanosomiasis - $15 million) and river blindness (onchocerciasis - $14.2 million) by the Bill & Melinda Gates Foundation These two parasitic diseases could be eliminated if new patient care tools are brought to bear. (dndi.org)
  • Announced today, these grants will run from 2020 until 2023 and will help deliver a single-dose cure for sleeping sickness, a terrifying and fatal disease, and greatly aid efforts to develop a short-course treatment for the millions of people at risk of river blindness in Central and West Africa. (dndi.org)
  • 'Both river blindness and sleeping sickness require innovative drugs to improve patient care or achieve elimination,' said Dr Bernard Pécoul, Executive Director of DND i . (dndi.org)
  • There has been great progress for these two diseases in recent years, with the delivery of fexinidazole , the first all-oral treatment for sleeping sickness developed by DNDi and Sanofi, and the approval in the US of moxidectin for river blindness. (dndi.org)
  • River blindness is transmitted by the bite of an infected blackfly and causes severe itching, skin lesions, and eventually blindness. (dndi.org)
  • The current approach to eliminating river blindness is based on the mass distribution of ivermectin, which has been tremendously successful in reducing disease prevalence. (dndi.org)
  • But these programs need to be repeated for 10-12 years as current treatments only kill the juvenile worms that cause river blindness, but not the adult worms, which can live more than 10 years in the human body. (dndi.org)
  • DND i aims to develop a safe, effective, affordable, and field-adapted 'macrofilaricidal' drug that can kill adult worms that cause river blindness. (dndi.org)
  • This could be used for individual patient treatment - current approaches are largely preventative targeting the larval stages only - with the potential for use as preventive chemotherapy to accelerate the elimination of river blindness in Africa in areas that are difficult to treat. (dndi.org)
  • I spent two weeks in the Southern Highlands of Tanzania visiting villages afflicted with River Blindness, a little-known but terrible disease that affects 40 million people worldwide. (eguiders.com)
  • Launching in early 2022, ' Code for a Cure - using AI to eliminate River Blindness' will see us join forces with the Bonn University to fight against one of the most neglected tropical diseases, River Blindness . (capgemini.com)
  • River blindness has currently infected more than 20 million people and has caused permanent blindness in more than one million. (capgemini.com)
  • After registering GDSC participants will team up to create an AI-based solution that will automate the current manual evaluation process, saving years of work and immensely speed up the availability of new treatments to patients infected by River Blindness. (capgemini.com)
Blue-yellow co3
Childhood blindness4
  • A first-of-its-kind gene therapy received approval from the Food and Drug Administration on Tuesday to treat a rare, inherited form of childhood blindness. (scientificamerican.com)
  • If you have a family history of congenital blindness, or conditions that can lead to childhood blindness, your healthcare team may be able to provide screenings that can give you an idea of how likely you may be to pass these conditions on to your children. (healthline.com)
  • A team of seven researchers collaborating from United States and Britain have found a way to use gene therapy to cure a rare form of childhood blindness that occurs due to a genetic predisposition. (news-medical.net)
  • In developing nations, 30%-72% of childhood blindness is avoidable [1]. (who.int)
Prevent blindness7
  • How do you prevent blindness? (healthline.com)
  • In an effort to educate the public on the various forms of Inflammatory Eye Disease (IED), Prevent Blindness has declared Sept. 27 - Oct. 3, 2021, as the first-ever Inflammatory Eye Disease Awareness Week. (preventblindness.org)
  • As part of this initiative, Prevent Blindness has created a dedicated webpage providing detailed information on IED, downloadable fact sheets in English and Spanish, and resources for eye care. (preventblindness.org)
  • Additionally, shareable social media graphics will be posted on the Prevent Blindness social media channels throughout the week. (preventblindness.org)
  • Prevent Blindness will feature a new episode in its Focus on Eye Health Expert Series , with an interview of Dr. Ann-Marie Lobo of the Illinois Eye and Ear Infirmary, Associate Professor of Ophthalmology, Co-Director, Uveitis Service, University of Illinois College of Medicine, Department of Ophthalmology and Visual Sciences. (preventblindness.org)
  • As with most eye diseases and conditions, access to quality eyecare and treatment can help prevent vision loss and even blindness from Inflammatory Eye Disease," said Jeff Todd, president and CEO of Prevent Blindness. (preventblindness.org)
  • According to Prevent Blindness , an estimated 8 percent of males and less than 1 percent of females have color vision problems. (allaboutvision.com)
Face Blindness19
Night blindness4
  • People born with mutated RPE65 genes suffer from severe vision problems, including night blindness. (scientificamerican.com)
  • Symptoms begin in early childhood with night blindness and restriction of visual field being the earliest noticeable effects and may eventually progress to complete blindness. (einnews.com)
  • This syndrome is characterized by night blindness, skeletal abnormalities (sloping shoulders, joint hyperextensibility, minor radiological anomalies) and characteristic facies (periorbital anomalies, malar flatness, retrognathia). (nih.gov)
  • When Do Symptoms of Night blindness-skeletal anomalies-dysmorphism syndrome Begin? (nih.gov)
Cause blindness4
Macular degeneration4
Color vision def3
  • Color blindness or color vision deficiency (CVD) is the decreased ability to see color or differences in color. (wikipedia.org)
  • Researchers also found that color blindness, or color vision deficiency, in boys is lowest in African-Americans, and confirmed that girls have a much lower prevalence of color blindness than boys. (medicalnewstoday.com)
  • Color blindness (or, more accurately, color vision deficiency) is an inherited condition that affects males more frequently than females. (allaboutvision.com)
Preventable blindness1
  • Chlamydia trachomatis is the leading cause of preventable blindness and bacterial sexually transmitted diseases worldwide. (cdc.gov)
Control of blindness3
  • Therefore, the control of blindness in children is considered a high priority within the WHO's VISION 2020: the Right to Sight initiative [2]. (who.int)
  • 9 India was the first country in the world to launch a 100% public funded programme for the control of blindness. (bmj.com)
  • The National Programme for Control of Blindness, a programme financially supported by public funds from the Government of India undertook a nationwide survey to assess the impact of the augmented national efforts for control of blindness over the period 1999-2001. (bmj.com)
Genetic7
  • In the UK, the £1.2 million RP Genome Project funded by sight loss charities RP Fighting Blindness and Fight for Sight, brings together leading genetic ophthalmology researcher centres in Leeds, London, Manchester and Oxford. (fightforsight.org.uk)
  • While effective, the downside to these approaches to vision rescue is that each disease requires its own form of gene therapy to correct the particular genetic mutation involved, a time consuming and complex process. (mvrf.org)
  • The most common form is caused by a genetic disorder called congenital red-green color blindness. (wikipedia.org)
  • Most color blindness is due to a genetic problem . (medlineplus.gov)
  • However, not all causes of blindness can be cured or even treated to help restore vision through laser treatment, correction surgery, genetic engineering, or stem cell therapy. (healthline.com)
  • The most common form of color blindness is genetic and involves a mutation or lack of genes that help the eye see red or green. (medicalnewstoday.com)
  • Newborns babies can be at risk of congenital blindness, presenting sight defects due to lesions or to genetic mutations in their genome. (news-medical.net)
Occurs3
CAUSES BLINDNESS1
  • But proving that the lack of these fatty acids actually causes blindness has been difficult to show in experiments, because mice in which the ELOVL4 was knocked out did not survive. (scienceblog.com)
Complete blindness2
  • This recent advisory from the FDA encompasses a total of 27 eye care products that have been linked to a concerning potential for severe infections, which could lead to drastic consequences, including the loss of vision or complete blindness. (yourlawyer.com)
  • The CRF has funded more than $4 million in scientific research for a treatment and/or cure for choroideremia (CHM), a rare and inherited retinal disease that causes visual impairment and potentially complete blindness. (einnews.com)
Congenital blindness2
  • There are several types of congenital blindness and other diseases that are present at birth and result in immediate or early blindness. (healthline.com)
  • Good prenatal care can help prevent some forms of congenital blindness, but many are the result of genetically programmed disorders that can't be avoided. (healthline.com)
Prevalence8
  • Caucasian male children have the highest prevalence among four major ethnicities, with 1 in 20 testing color blind, according to the first major study of color blindness in a multi-ethnic group of preschoolers. (medicalnewstoday.com)
  • The prevalence of color blindness in girls measured 0 percent to 0.5 percent for all ethnicities, confirming findings in prior studies. (medicalnewstoday.com)
  • Objective The objective of this study was to determine the prevalence of blindness and its determinants in Bangladeshi adult population. (bmj.com)
  • The age-standardised prevalence, after best correction, of blindness and low vision was 1.0% (95% CI 0.5% to 1.4%) and 12.1% (95% CI 10.5% to 13.8%), respectively. (bmj.com)
  • Prevalence of cataract blindness was 5.3% (95% CI: 4.97 to 5.62). (bmj.com)
  • Reduction in blindness prevalence among people aged 50 years and above was observed compared to earlier studies. (bmj.com)
  • Blindness control efforts seem to have played a part in arresting the increasing prevalence of blindness in India and there is hope that the goals of the "Vision 2020-right to sight" initiative can be achieved if there is strong political will and prioritised action. (bmj.com)
  • 12 Results from the survey indicate that the country may now see a recession in blindness prevalence in the future. (bmj.com)
Sight2
  • Seva is a global nonprofit eye care organization that transforms lives and strengthens communities by restoring sight and preventing blindness. (seva.org)
  • From Homer to Helen Keller, from Dune to Stevie Wonder, from the invention of braille to the science of echolocation, M. Leona Godin explores the fascinating history of blindness, interweaving it with her own story of gradually losing her sight. (greenapplebooks.com)
Achromatopsia3
Inability4
Varied during the prog1
  • Hoping to develop a treatment that works more broadly across diseases, a Penn Vet team used canine disease models to closely examine how retinal gene activity varied during the progression of three different forms of inherited vision disease. (mvrf.org)
Prevention1
  • Strategies for the prevention of blindness in national programmes : a primary health care approach. (who.int)
Cataract4
  • This nationally representative population-based survey indicates that more than 1 in 10 Bangleashi adults aged ≥40 years have low vision or blindness, with cataract being the single most attributing factor. (bmj.com)
  • Cataract was responsible for 62.4% of bilateral blindness. (bmj.com)
  • Recently, a nationwide survey was undertaken (1999-2001) to document the current situation, trends over the past three decades, and to evaluate the impact of the World Bank supported Cataract Blindness Control Project in the country. (bmj.com)
  • The states also included seven states where a World Bank assisted cataract blindness control project was operational from 1994. (bmj.com)
Donate2
Common10
  • The most common cause of color blindness is an inherited problem or variation in the functionality of one or more of the three classes of cone cells in the retina, which mediate color vision. (wikipedia.org)
  • Males are more likely to be color blind than females, because the genes responsible for the most common forms of color blindness are on the X chromosome. (wikipedia.org)
  • This is the most common type of color blindness. (medlineplus.gov)
  • This article will review some of the most common causes of blindness that can be cured and what treatments could offer for people experiencing complete vision loss. (healthline.com)
  • Open-angle glaucoma, the most common form, results in increased eye pressure. (cdc.gov)
  • Red-green color deficiency is the most common form of color blindness. (allaboutvision.com)
  • Recently, Dr. McCall's team developed a mutant NIH miniature swine model of a common form of autosomal dominant RP (Pro23His rhodopsin mutation) in collaboration with the National Swine Resource Research Center at University of Missouri. (einnews.com)
  • As a result, some people have trouble telling the difference between red and green (the most common kind of color blindness), and between blue and yellow. (akronchildrens.org)
  • Conclusions Low vision and blindness are common problems in those aged 40 years or older. (bmj.com)
  • For adults in the United States, a complication of diabetes known as diabetic retinopathy is the most common cause of blindness. (doctordisability.com)
Colors7
  • The colors that are confused are very consistent among people with the same type of color blindness. (wikipedia.org)
  • Confusion colors for red-green color blindness include: cyan and grey rose-pink and grey blue and purple yellow and neon green red, green, orange, brown Confusion colors for tritan include: yellow and grey blue and green dark blue/violet and black violet and yellow-green red and rose-pink These colors of confusion are defined quantitatively by straight confusion lines plotted in CIEXYZ, usually plotted on the corresponding chromaticity diagram. (wikipedia.org)
  • Cole describes four color tasks, all of which are impeded to some degree by color blindness: Comparative - When multiple colors must be compared, such as with mixing paint Connotative - When colors are given an implicit meaning, such as red = stop Denotative - When identifying colors, for example by name, such as "where is the yellow ball? (wikipedia.org)
  • A parent may notice signs of color blindness when a young child is first learning colors. (medlineplus.gov)
  • Special contact lenses and glasses may help people with color blindness tell the difference between similar colors. (medlineplus.gov)
  • People with this form of color blindness cannot tell the difference between the two colors. (medicalnewstoday.com)
  • Parents or teachers may suspect color blindness if a child seems to have trouble seeing certain colors. (akronchildrens.org)
People9
  • JBIR is the first scholarly journal created by blind people to address the real problems of blindness. (nfb.org)
  • In certain countries, color blindness may make people ineligible for certain jobs, such as those of aircraft pilots, train drivers, crane operators, and people in the armed forces. (wikipedia.org)
  • This phenomenon is known as 'inattentional blindness' because people typically do not consciously perceive aspects of their world that fall outside of the focus of their attention," Simons writes on his website. (waldenu.edu)
  • Choroideremia (CHM) is a rare inherited form of blindness affecting approximately 1 in 50,000 people. (einnews.com)
  • Finding genes for retinal degenerations has immediate benefits for people living with blindness and vision loss, their families, and their physicians. (news-medical.net)
  • Many people with color blindness don't even know it. (akronchildrens.org)
  • Some people can use special contact lenses and glasses to help them see some color differences, but there is no cure for color blindness. (akronchildrens.org)
  • People make jewelry, silverware, electronic equipment, and dental fillings with silver in its metallic form. (cdc.gov)
  • Silver is stable and remains in the environment in one form or another until it is taken out again by people. (cdc.gov)
Genes2
  • This is the first paper resulting from our programme to improve patient diagnosis by finding novel disease-causing genes through collaboration between research institutions and in partnership with RP Fighting Blindness. (fightforsight.org.uk)
  • Females who are not color-blind can carry genes for color blindness and pass them on to their children. (wikipedia.org)
Gene therapy1
  • A panel of advisors to the United States Food and Drug Administration (FDA) has voted unanimously in favor of an experimental gene therapy to treat patients with a rare kind of hereditary blindness. (news-medical.net)
Bilateral1
  • 3 = Bilateral hemianopia (blind including cortical blindness) stimulation is performed at this point. (medscape.com)
Diseases2
  • The team examined three forms of retinal degenerative diseases, rod cone dysplasia 1 being the most severe, or earliest onset, followed by X-linked progressive retinal atrophy 2 and then early retinal degeneration. (mvrf.org)
  • Glaucoma is a group of diseases that damage the eye's optic nerve and can result in vision loss and even blindness. (cdc.gov)
Eliminate1
  • These observations highlight the need to respond to the WHO's Global Action Plan by scaling up of our current efforts at global, regional, and country levels, to eliminate the burden of unnecessary blindness and vision impairment. (iapb.org)
Vision loss1
Symptoms2
Ophthalmology2
  • Scientists from the University of Leeds, in collaboration with researchers from the Institute of Ophthalmology in London and Ghent University in Belgium, have discovered that mutations in the gene DRAM2 cause a new type of late-onset inherited blindness. (fightforsight.org.uk)
  • Many times children with color blindness will perform poorly on tests or assignments that employ color coded materials, leading color blind children to be inappropriately classified by ability at school, said the study's principal investigator Rohit Varma, M.D., chairman of the Department of Ophthalmology at the University of Southern California (USC) Keck School of Medicine and director of the USC Eye Institute. (medicalnewstoday.com)
Manuscript2
  • Submissions may be made to JBIR by completing the below submission form and uploading the manuscript. (nfb.org)
  • The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. (lu.se)
Deficiency2
Treatment5
  • This will take researchers one step closer to addressing multiple forms of disease with one treatment. (mvrf.org)
  • What we have in mind is to be able to address multiple forms of disease with one treatment," Beltran said. (mvrf.org)
  • A new treatment for patients with a form of congenital retinal blindness has shown success in improving vision, according to results published today in Nature Medicine led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania. (news-medical.net)
  • DfID-funded research in 2016 showed that after receiving treatment in the form of minor surgery or the provision of glasses, 78% of adults surveyed reported an improvement in their quality of life and an increase in household income after the treatment! (iapb.org)
  • There is no treatment for the disease, although there is evidence that nutrition supplements and protecting eyes from UV rays might be beneficial in slowing the progression of blindness. (scienceblog.com)
Problems2
Rare1
  • Type 3, a rare dominant form of Stargardt disease, is caused by a mutation in ELOVL4, a gene that encodes an enzyme that helps to make fatty acids obtained through our diet into forms that can be incorporated into cell membranes. (scienceblog.com)
Retina1
  • therefore, the optic nerve must cross through the retina en route to the brain. (wikipedia.org)
Type3
  • The lines all intersect at a copunctal point, which varies with the type of color blindness. (wikipedia.org)
  • Insulin-resistant, or type 2, diabetes is the predominant form. (medscape.com)
  • Vision scientists long have thought that lack of very long chain fatty acids in photoreceptor cells caused blindness in children with Stargardt type 3 retinal degeneration, an incurable eye disease. (scienceblog.com)
Typically1
Cure3
Severe form1
  • Travelers to endemic areas may have a particularly severe form of dermatitis. (medscape.com)
Widely1
  • The major causes of blindness vary widely from region to region, being largely determined by socioeconomic development and the availability of primary health care and eye services. (who.int)
Mutation1
  • One example is a specific form of retinal dystrophy caused by a mutation in the RPE65 gene. (healthline.com)
Visual4
  • This study in 2005 evaluated the causes and major anatomical site of blindness and severe visual loss at a school for blind children in Isfahan province, Islamic Republic of Iran. (who.int)
  • A person's age and a family history of blindness or other forms of visual impairment create a greater risk. (doctordisability.com)
  • Patients with ocular trauma, bandages, pre-existing blindness or other 2 = Forced deviation, or total gaze paresis not overcome by the disorder of visual acuity or fields should be tested with reflexive oculocephalic maneuver. (medscape.com)
  • If there is unilateral ______ blindness or enucleation, visual fields in the remaining eye are scored. (medscape.com)
Condition4