• Close examination demonstrated the scalp hairs were very brittle, coarse, wiry in texture, and broke off quite easily with mechanical trauma such as combing and brushing. (wikipedia.org)
  • 1,2 The scalp contains a high density of hair growth with an abundance of sebaceous glands. (naturalmedicinejournal.com)
  • Scalp hair growth and patterning are closely associated with the development of the central nervous system. (medscape.com)
  • A number of genetic, metabolic, and neurologic disorders are associated with recognizable scalp hair abnormalities. (medscape.com)
  • For this reason, a systematic step-by-step assessment of the hair and scalp should be an integral part of every initial newborn physical assessment. (medscape.com)
  • This article reviews the clinically relevant embryology related to fetal scalp hair formation. (medscape.com)
  • A systematic review of typical newborn scalp hair characteristics such as color, quantity, texture, direction of growth, hairlines, and hair whorls is provided. (medscape.com)
  • Clinical inspection of scalp hair characteristics can provide important clues to aid the early identification of genetic, metabolic, and neurologic disorders. (medscape.com)
  • [ 3 , 4 ] An understanding of the embryologic development and cycles of scalp hair growth will aid the clinician in assessing infants of various gestational and postnatal ages. (medscape.com)
  • Cite this: Scalp Hair Characteristics in the Newborn Infant - Medscape - Dec 01, 2003. (medscape.com)
  • Amino acid analyses of control hair when compared with those of patients with the Sabinas syndrome showed very striking differences with regard to content of sulphur amino acids. (wikipedia.org)
  • The key finding is brittle hair with low sulfur content, but alternating dark and light bands under polarizing microscopy, trichoschisis, and absent or defective cuticle are additional important clues for the diagnosis of trichothiodystrophy. (wikipedia.org)
  • A clinical study was designed to observe the efficacy of MSM as an oral supplement ( OptiMSMĀ® [Bergstrom Nutrition, Vancouver, Washington, USA]) for mitigating hair loss and improving hair thickness and density as well as overall appearance via subject perception and micrometric measurements of hair thickness. (naturalmedicinejournal.com)
  • Significant improvements of hair density, hair-density terminal, and hair diameter were observed after 120 days of OptiMSM use. (naturalmedicinejournal.com)
  • Hair is made up of 95% keratin, synthesized by the epidermal keratinocytes. (naturalmedicinejournal.com)
  • Keratin is insoluble in water, thus conferring impermeability and protection for the hair. (naturalmedicinejournal.com)
  • 6 Keratin is especially rich in cysteine, which is a sulfur-containing amino acid capable of forming disulfide bonds between molecules, thus adding strength and elasticity to the entire structure (Figure 1). (naturalmedicinejournal.com)
  • The cortex is in the center of each hair fiber and consists of long, tightly packed keratin spindles stabilized by disulfide bonds. (naturalmedicinejournal.com)
  • 7 When sulfur is readily available, keratin is made from strong disulfide bonds. (naturalmedicinejournal.com)
  • Trichothiodystrophy represents a central pathologic feature of a specific hair dysplasia associated with several disorders in organs derived from ectoderm and neuroectoderm. (wikipedia.org)
  • Trichothiodystrophy or TTD is a heterogeneous group of autosomal recessive disorders, characterized by abnormally sulfur deficient brittle hair and accompanied by ichthyosis and other manifestations. (wikipedia.org)
  • [ 1 3 ] A number of autosomal dominant, autosomal recessive, and X-linked single gene disorders are characterized by hair abnormalities. (medscape.com)
  • Review of literature reveals extensive associated findings in trichothiodystrophy. (wikipedia.org)
  • The initial assessment of all newborns should include a systematic assessment of hair color, quantity, texture, direction of growth, hairlines, and hair whorls. (medscape.com)
  • Because the disease appears to be inherited in an autosomal recessive pattern, detection of low-sulfur brittle hair syndrome is also important for genetic counseling. (wikipedia.org)
  • Sabinas brittle hair syndrome is inherited as an autosomal recessive genetic trait. (wikipedia.org)
  • Conditions associated with abnormal hair color, quality, quantity, and distribution are presented in a series of clinical photographs, and their salient features are discussed. (medscape.com)
  • Based on the confines and conditions of this study, MSM supplementation was effective in reducing hair loss and improving hair diameter and thickness. (naturalmedicinejournal.com)
  • Symptoms include brittle hair, mild mental retardation and nail dysplasia. (wikipedia.org)
  • A pattern of hair growth characterized by a clockwise spiral or coil. (medscape.com)
  • The subjects observed growth of new hairs and declared that their hair was more voluminous and less brittle after 45, 90, and 120 days of product use. (naturalmedicinejournal.com)
  • Normal cycles of hair growth and loss are discussed. (medscape.com)
  • Patterns of hair growth can be abnormal, serving as external markers of underlying structural brain and central nervous system abnormalities. (medscape.com)
  • First phase in hair cycle characterized by growth of hair follicles. (medscape.com)
  • Usually describes lack of any hair growth. (medscape.com)
  • Some hairs could be visualized in their follicles, which were broken off at the skin line. (wikipedia.org)
  • The principal biochemical features of the illness are reduced hair cystine levels, increased copper/zinc ratio, and presence of arginosuccinic acid in the blood and urine. (wikipedia.org)