• glycoprotein hormones
  • The protein dimer contains 2 glycopeptidic subunits, labeled alpha and beta subunits, that are non-covalently associated (i.e., without any disulfide bridge linking them): The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids in human but 96 amino acids in almost all other vertebrate species (glycoprotein hormones do not exist in invertebrates). (wikipedia.org)
  • ovulation
  • This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. (wikipedia.org)
  • Conclusion: Cycle day 3 FSH levels are predictive of the ovulation response and probability of pregnancy in stimulated cycles and can be of value in patient selection and counseling in IVF and GIFT programs. (sun.ac.za)
  • This "LH surge" triggers ovulation, thereby not only releasing the egg from the follicle, but also initiating the conversion of the residual follicle into a corpus luteum that, in turn, produces progesterone to prepare the endometrium for a possible implantation. (wikipedia.org)
  • In 1958 Gemzell was the first to show that extracted gonadotropins containing FSH could be used as fertility medication to stimulate ovulation in women with anovulatory infertility. (wikipedia.org)
  • Whereas nafarelin acetate in a nasal spray induces a short lived LH surge that is high enough to induce ovulation in large follicles, but too short lived to adversely affect small follicles. (wikipedia.org)
  • ovaries
  • The test may also be used to check for damage or disease of the testes or ovaries, pituitary gland, or hypothalamus, an almond-sized area of the brain that links the nervous system with the hormone-producing endocrine system. (rchsd.org)
  • Due in part to elevated LH levels, which stimulate androgen production by theca cells in the ovaries, and due in part to FSH insensitivity, resulting in a lack of aromatase in nearby granulosa cells that normally convert androgens into estrogens, it could be expected that females with FSH insensitivity might present with symptoms of hyperandrogenism at puberty. (wikipedia.org)
  • androgen
  • The Leydig cells produce testosterone (T) under the control of LH, which regulates the expression of the enzyme 17β-hydroxysteroid dehydrogenase that is used to convert androstenedione, the hormone produced by the testes, to testosterone, an androgen that exerts both endocrine activity and intratesticular activity on spermatogenesis. (wikipedia.org)
  • stimulation
  • AFC and FSH Stimulation Recommendations for Cycles Using Assisted Reproduction Technology Declining serum levels of anti-müllerian hormone. (wikipedia.org)
  • testosterone
  • In boys, FSH and LH work together to get the testes to begin producing testosterone, the hormone responsible for the physical changes of puberty and the production of sperm. (rchsd.org)
  • In males, where LH had also been called interstitial cell-stimulating hormone (ICSH), it stimulates Leydig cell production of testosterone. (wikipedia.org)
  • ovary
  • For VFC, the FSH portion targets the protein to the ovary and stimulates follicle growth, whereas VEGF enhances local vascular development. (biomedsearch.com)
  • The human ovary contains a population of primordial follicles. (wikipedia.org)
  • At 18-22 weeks post-conception, the female ovary contains its peak number of follicles (about 300,000 in the average case, but individual peak populations range from 35,000 to 2.5 million). (wikipedia.org)
  • inhibin
  • Inhibin, activin, and sex hormones do not affect genetic activity for the beta subunit production of LH. (wikipedia.org)
  • Although FSH and more recently Inhibin B have been shown to have some correlation with ovarian reserve, it is now well established that Anti-Mullerian Hormone or AMH is more useful biochemical test. (wikipedia.org)
  • atresia
  • It has been proposed that enhanced levels of Nitrogen oxide in rats can prevent atresia of the ovarian follicle, and depressed levels have the opposite effect. (wikipedia.org)
  • In addition, the remaining follicles that were recruited towards maturation are lost by atresia. (wikipedia.org)
  • activin
  • The TGF beta superfamily of ligands include: Bone morphogenetic proteins (BMPs), Growth and differentiation factors (GDFs), Anti-müllerian hormone (AMH), Activin, Nodal and TGFβ's. (wikipedia.org)
  • oocytes
  • Mean number of oocytes retrieved per number of follicles aspirated on the day of ovum pick up was calculated. (clinicaltrials.gov)
  • Basal hormone levels were compared to the peak E2 concentration, the number of follicles aspirated, and the number of preovulatory oocytes recovered following drug therapy. (sun.ac.za)
  • This increases the likelihood of the small follicles and oocytes therein developing normally for upcoming cycles and also allows the woman to cycle without taking a break and consequently increases the probability of conception in poor ovarian reserve women and advanced reproductive aged women. (wikipedia.org)
  • growth
  • Because most prostate cancer cells rely on these hormones for growth and survival, nilutamide can slow the progression of prostate cancer and extend life in men with the disease. (wikipedia.org)
  • Therapy
  • Hormone Replacement Therapy can be likened to an 'oasis in the desert' for women in the throes of menopause. (medindia.net)
  • It has also been studied as a component of feminizing hormone therapy for transgender women and to treat acne and seborrhea in women. (wikipedia.org)
  • Nilutamide has been studied for use as a component of feminizing hormone therapy for transgender women. (wikipedia.org)
  • cancers
  • Contraindications of desogestrel include: Allergy to desogestrel or any other ingredients Active thrombosis (deep vein thrombosis or pulmonary embolism) Jaundice or severe liver disease Hormone-sensitive cancers (e.g., breast cancer) Unexplained vaginal bleeding Desogestrel is not indicated for use in pregnancy. (wikipedia.org)