Field heteronuclear magnetic resonance spectroscopy. Medical search. Frequent questions

Pal S, Chandrakumar N. ( 2009 ) Study of dynamics in pentachlorophenol in the solid state by 1D Nuclear Quadrupole Resonance exchange spectroscopy Molecular Physics . (academictree.org)
Pal S, Chandrakumar N. ( 2008 ) Nuclear quadrupole resonance exchange spectroscopy with shaped radiofrequency pulses Molecular Physics . (academictree.org)
From 1988 to 1995 we have pioneered the development and application of certain techniques for the study of quadrupolar nuclei, such as 2H exchange spectroscopy, quadrupole nutation and double rotation, and satellite transition spectroscopy [1-3]. (ua.pt)

Correlation spectroscopy is a development of ordinary NMR. (wikipedia.org)
Sensitivity-enhanced two-dimensional heteronuclear shift correlation NMR spectroscopy. (microbiologyresearch.org)
The chemical structure of the new molecule was fully characterized by proton nuclear magnetic resonance ( 1 H-NMR), carbon-13 nuclear magnetic resonance ( 13 C-NMR), heteronuclear single quantum coherence (HSQC), correlation spectroscopy ( 1 H- 1 H-COSY), distortionless enhancement by polarization transfer (DEPT), mass spectrometry, Fourier-transform infrared (FTIR), and ultraviolet (UV) spectroscopies. (mdpi.com)

Perturbation of this nature was also observed in magnetically aligned bicelles by 31P solid-state NMR spectroscopy and spin relaxation experiments. (phoenixpeptide.com)

Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei. (wikipedia.org)
Certain atomic nuclei can absorb and emit radio frequency energy when placed in an external magnetic field . (alchetron.com)
NMR, or Nuclear Magnetic Resonance, is a trusted analytical method that uses the natural magnetic properties of atomic nuclei. (nmr-nl.org)
NMR spectroscopy, the experimental process tied to NMR, produces valuable data by having atomic nuclei interact with a magnetic field. (nmr-nl.org)

The gradient has been optimized for durability and makes a wide variety of NMR techniques accessible, including gradient enhanced solvent suppression and artefact-free homonuclear and heteronuclear 2D experiments. (bruker.com)

In nuclear magnetic resonance, the magnetization of abundantly present nuclei contributes to the overall field felt by the same nuclei through intermolecular dipolar interactions. (copernicus.org)
In this work, the effect of the dipolar field under continuous irradiation is investigated. (copernicus.org)
By spinning at the magic angle (54.7°), line broadening effects due to magnetic susceptibility differences and dipolar interactions within the sample are removed, enhancing spectral resolution, and enabling detailed analysis of the individual components within the sample. (bruker.com)

These instruments are capable of various multi-dimensional heteronuclear 1 H ⁄ 2 H ⁄ 13 C ⁄ 15 N ⁄ 31 P NMR experiments. (utmb.edu)
Experimental methods of multi-dimensional NMR spectroscopy, dynamics and theoretical description of spin system evolution, multiple resonance NMR technique for structural studies of proteins and nucleic acids by NMR spectroscopy, contemporary methods of structural biology, studies of complex biomolecular systems. (muni.cz)

The research work carried out is focused on the design and application of new and modern NMR methodologies (i) to perform efficient broadband 1 H homodecoupling in 1D/2D NMR experiments and (ii) to accurately determine homo- and heteronuclear coupling constants in isotropic and anisotropic conditions through improved HSQC and HSQMBC-type experiments. (uab.cat)
was honoured at the 56th Experimental Nuclear Magnetic Resonance Conference (ENC) with the Ritchey Travel Award for her Ph.D. Thesis research on "Development and application of modern pure shift NMR techniques and improved HSQC/HSQMBC experiments" . (uab.cat)
Our experience includes experimental data for resonance assignments and information about molecular dynamic processes retrieved from 15 N relaxation experiments. (edu.pl)
The use of spherical rotors for magic angle spinning offers a number of advantages, including improved sample exchange, efficient microwave coupling for dynamic nuclear polarization nuclear magnetic resonance (NMR) experiments, and, most significantly, high frequency and stable spinning with minimal risk of rotor crash. (copernicus.org)
In order to make spherical rotors robust and accessible for magnetic resonance experiments and to design apparatuses capable of achieving very high MAS rates, we examined the spinning and stabilization mechanisms of these spherical rotors. (copernicus.org)
Particular themes have included improving lineshapes, the measurement of coupling constants, the suppression of zero-quantum coherence, the application of pulsed field gradients (especially to NOE experiments), and pure shift techniques. (smashnmr.org)

In nuclear Overhauser effect (NOE) spectroscopy, the relaxation of the resonances is observed. (wikipedia.org)

Besides identification, NMR spectroscopy provides detailed information about the structure, dynamics, reaction state, and chemical environment of molecules. (wikipedia.org)
Nuclear magnetic resonance (NMR) spectroscopy is a versatile tool that provides information on structures and dynamics of various biological and synthetic molecules at an atomic level. (utmb.edu)
2020 ) Assessment of the Role of TFE Solvent Dynamics in Inducing Conformational Transitions in Melittin: An Approach with Solvent F Low Field NMR Relaxation and Overhauser DNP Studies. (academictree.org)
IK's Spin Dynamics Group at the University of Southampton are currently global leaders in large-scale simulations of magnetic resonance systems: they invented linear complexity scaling methods for time-domain spin dynamics. (southampton.ac.uk)
NMR has ushered in a new era of scientific discovery in fields ranging from chemistry to biochemistry and medicine, providing invaluable insights into the structure, dynamics, and interactions of molecules. (nmr-nl.org)

Pulses of radio waves excite the nuclear spin energy transition, and magnetic field gradients localize the signal in space. (alchetron.com)
The magnet generates a robust, uniform magnetic field while the RF transmitter emits radiofrequency energy pulses. (nmr-nl.org)

Chaubey B, Chandrakumar N, Pal S. ( 2021 ) Preferential solvation of carbohydrates in water-trifluoroethanol mixtures: a solvent detected heteronuclear NMR approach. (academictree.org)

Spectral density mapping at multiple magnetic fields suitable for C-13 NMR relaxation studies. (muni.cz)

The aim of this research was the preparation and structural characterization of heteronuclear molybdenum(VI) and copper(II) complexes with symmetrical disubstituted (thio)carbohydrazides derived from 2-hydroxybenzaldehyde or 2-hydroxy-3-methoxybenzaldehyde. (unizg.hr)
Currently, the improvement of detection modalities (i.e., direct detection of 13 C isotopomers), the progress in building adequate mathematical models along with the increase in magnetic field strength now available render possible detailed compartmentalized metabolic flux characterization. (frontiersin.org)
Chemical characterization by nuclear magnetic resonance spectroscopy indicated that the free amino acid L-tryptophan was the natural sperm attractant in H. rufescens . (biologists.com)
One major field of industrial applications of HRMAS NMR is the characterization of insoluble polymers swollen in a suitable solvent. (bruker.com)

He combines subjects such as Fibril, NMR spectra database, Hydrogen bond and Intermolecular force with his study of Solid-state nuclear magnetic resonance. (research.com)
The resulting highly resolved 1 H NMR spectra display resonances as collapsed singlets, therefore minimizing signal overlap and expediting spectral analysis. (uab.cat)
The T1 and T2 relaxations are not spectra like those obtained by a high-field NMR system (e.g., 300-600 MHz) but only curves in which the NMR signal recovers or decays according to a specific rule. (bvsalud.org)
Our facility has expertise in the structural analysis of biomolecules in solution based on two- and three-dimensional homo- and heteronuclear spectra. (edu.pl)
Triple probe heads allow the measurement of two- and three-dimensional homo- and heteronuclear spectra. (edu.pl)
High-resolution, solution-state 2D 1 H- 13 C HSQC NMR spectroscopy has proven to be an effective tool for rapid and reproducible fingerprinting of the numerous polysaccharides and lignin components in unfractionated plant cell wall materials, and is therefore a powerful tool for cell wall profiling based on our ability to simultaneously identify and comparatively quantify numerous components within spectra generated in a relatively short time. (biomedcentral.com)
He published the first silicon NMR spectra and pioneering work on phosphorus, fluorine, and tin NMR spectroscopy. (chemistryworld.com)
With standard solution-state NMR techniques, the spectra of such samples would suffer from broad and unresolved resonances. (bruker.com)

High-resolution, solution-state 2D 1 H- 13 C HSQC NMR spectroscopy has proven to be an effective tool for rapid and reproducible fingerprinting of the numerous polysaccharides and lignin components in unfractionated plant cell wall materials [ 7 - 11 ]. (biomedcentral.com)

Additionally, he developed the OPSY family of pulse sequences (Only Parahydrogen SpectroscopY), enabling efficient selection of para-hydrogen hyperpolarized signals for the first time. (dur.ac.uk)
NMR spectroscopy uses specific pulse sequences to manipulate nuclear spins and gather valuable information. (nmr-nl.org)

This work was the beginning of a joint tackling of the theoretical and experimental chemical physics underlying magnetic resonance. (weizmann.ac.il)
Our department comprises a wide range of experimental and computational research programs directed by renowned scientists, many of whom are international leaders in their fields. (auburn.edu)

The sample is placed in a magnetic field and the NMR signal is produced by excitation of the nuclei sample with radio waves into nuclear magnetic resonance, which is detected with sensitive radio receivers. (wikipedia.org)
The most common types of NMR are proton and carbon-13 NMR spectroscopy, but it is applicable to any kind of sample that contains nuclei possessing spin. (wikipedia.org)
Nuclei with an odd number of protons or neutrons have a unique property called spin that generates an extremely small magnetic moment. (nmr-nl.org)
When exposed to an external magnetic field, these nuclei rotate and align either parallel (low energy state) or anti-parallel (high energy state) to the field. (nmr-nl.org)
These interactions arise from the magnetic coupling between nuclei that have a spin, such as hydrogen atoms in organic molecules. (nmr-nl.org)

Infra-red (IR) spectroscopy is one of the most common and widely used spectroscopic techniques. (textilestudycenter.com)

As the fields are unique or highly characteristic to individual compounds, in modern organic chemistry practice, NMR spectroscopy is the definitive method to identify monomolecular organic compounds. (wikipedia.org)
His work deals with themes such as Supramolecular chemistry, Fibril, Scanning transmission electron microscopy, Intermolecular force and Nuclear magnetic resonance spectroscopy, which intersect with Solid-state nuclear magnetic resonance. (research.com)
Crystallography, Molecule, Ionic liquid, Inorganic chemistry and Nuclear magnetic resonance spectroscopy are his primary areas of study. (research.com)
The concepts of his Inorganic chemistry study are interwoven with issues in Solid-state nuclear magnetic resonance and Aqueous solution. (research.com)
Magnetic Resonance in Chemistry, 2015. (uab.cat)
James has been awarded the Royal Society of Chemistry Meldola Medal, the University of Cambridge Pilkington Teaching Prize, and the Royal Society of Chemistry Silver Medal for contributions in Magnetic Resonance. (smashnmr.org)
In the field of chemistry, NMR is utilized in determining the structure of molecules, exploring reaction mechanisms, and verifying the purity of compounds. (nmr-nl.org)
Paul Lauterbur, University of Illinois professor of chemistry and pioneer of magnetic resonance imaging (MRI), died of kidney disease on 27 March 2007 at his home in Urbana, Illinois, US. (chemistryworld.com)

The principle of NMR usually involves three sequential steps: The alignment (polarization) of the magnetic nuclear spins in an applied, constant magnetic field B0. (wikipedia.org)
During the last decade Shimon embarked on yet another venture: understanding the mechanism of dynamic nuclear polarization (DNP) at high magnetic fields. (weizmann.ac.il)

They can be analysed by HRMAS spectroscopy in their original form in an easy and convenient manner, without prior sample treatment. (bruker.com)

After PhD graduation Shimon became Alex Pines' first postdoc at Berkeley, where they made pioneering discoveries in the new field of multiple-quantum NMR. (weizmann.ac.il)
This work, along with the multi-quantum concept, served as basis for additional future developments in the field that resulted in a wide variety of materials-oriented research. (weizmann.ac.il)

Modern NMR spectrometers have a very strong, large and expensive liquid helium-cooled superconducting magnet, because resolution directly depends on magnetic field strength. (wikipedia.org)
There are even benchtop nuclear magnetic resonance spectrometers. (wikipedia.org)
The facility is equipped with two three-channel Varian NMR spectrometers working at a magnetic field strength of 9.4 and 11.7 T, corresponding to 400 and 500 MHz 1 H resonance frequencies, respectively. (edu.pl)

CO2) and catalytic properties [19] and, very recently, in ii) structural elucidation of biosolids (e.g., biomacromolecules) and iii) combining high-resolution solid-state NMR at high magnetic fields, X-ray diffraction and computational approaches to study packing interactions (e.g., weak CH∙∙∙X and CH∙∙∙p / strong hydrogen bonds and p∙∙∙p interactions) on pharmaceutical hydrates/anhydrates systems [18]. (ua.pt)

Our facility provides services for the nuclear magnetic resonance (NMR) spectroscopy of biomolecules (peptides, proteins, RNA, DNA). (edu.pl)

This review aims at presenting the most recent advances in pure shift NMR spectroscopy, with a particular emphasis to the Zangger-Sterk experiment. (uab.cat)
Dr Aguilar played a key role in pioneering the field of pure shift NMR, which is regarded as one of the most significant innovations in NMR over the past decade. (dur.ac.uk)
Working across more than just spectroscopy, Krish has also led a microimaging team and developed an in-vivo osteoarthritis biomarker method based on the use of residual chemical shift anisotropy of H 2 O in cartilage and time domain data processing. (smashnmr.org)

The intramolecular magnetic field around an atom in a molecule changes the resonance frequency, thus giving access to details of the electronic structure of a molecule and its individual functional groups. (wikipedia.org)
His Molecule research includes themes of Pyridine, Ionic bonding, Electron paramagnetic resonance, Dithiocarbamate and Anisotropy. (research.com)
His main research concerns Ionic liquid, Crystallography, Nuclear magnetic resonance spectroscopy, Molecule and Thermal analysis. (research.com)
His Crystallography research incorporates themes from Dithiocarbamate and Heteronuclear molecule. (research.com)
In recent years, a great interest in the development of new broadband 1 H homonuclear decoupled techniques providing simplified J HH multiplet patterns has emerged again in the field of small molecule NMR. (uab.cat)

The perturbation of this alignment of the nuclear spins by a weak oscillating magnetic field, usually referred to as a radio-frequency (RF) pulse. (wikipedia.org)
The Carr-Purcell-Meiboom-Gill (CPMG) pulse sequence is a fundamental tool in NMR spectroscopy, which is widely used for the suppression of protein signals for metabolomic and drug discovery applications. (dur.ac.uk)

This requires a spectral library, ideally one that has been recorded for the same field strength and sample conditions (e.g. solvent composition, buffer, sample pH and temperature). (biomedcentral.com)

The major degradation product was isolated and fully characterized using atmospheric chemical ionization-mass spectrometry and nuclear magnetic resonance techniques. (bvsalud.org)
Resonance Group, Chemical of the globular proteins bovine pancreatic trypsin inhibitor (BPTI) and Center, Lund University ubiquitin in aqueous solution. (lu.se)

MRI scanners use strong magnetic fields , radio waves , and field gradients to generate images of the inside of the body. (alchetron.com)

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy. (microbiologyresearch.org)

With the development and optimization of non-invasive techniques, such as nuclear magnetic resonance spectroscopy (MRS), several groups have worked on assessing cerebral metabolism in vivo . (frontiersin.org)

Fisher information in Time-Domain Spectroscopy (arXiv, 2023) [ pdf ]. (lu.se)

Despite wide-spread use of Nuclear Magnetic Resonance (NMR) in metabolomics for the analysis of biological samples there is a lack of graphically driven, publicly available software to process large one and two-dimensional NMR data sets for statistical analysis. (biomedcentral.com)

Journal of Magnetic Resonance. (berkeley.edu)
Journal of Magnetic Resonance , 190 , 316-326. (au.dk)
Journal of Magnetic Resonance Series A. 113(2):169-176. (berkeley.edu)
Journal of Magnetic Resonance Series B. 108:170-172. (manchester.ac.uk)

In 2007 we initiated in Aveiro (with F. Taulelle) the international event 'SMARTER - Structure elucidation by coMbining mAgnetic Resonance, compuTation modEling and diffRactions', bridging scientific communities. (ua.pt)

His scientific interests lie mostly in Crystallography, Solid-state nuclear magnetic resonance, Peptide, Protein structure and Stereochemistry. (research.com)

Magnetic resonance imaging ( MRI ) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body in both health and disease. (alchetron.com)

Infrared spectroscopy, radiation with wavelengths between 1 -15 μm is absorbed at certain characteristic frequencies, which yield structural information. (textilestudycenter.com)
Lauterbur's breakthrough idea was to vary the strength of the magnetic field from place to place, so that different parts of the object emitted radio waves of different frequencies. (chemistryworld.com)

Absorption of radio waves in the presence of magnetic field is accompanied by a special type of nuclear transition, and for this reason, such type of spectroscopy is known as Nuclear Magnetic Resonance Spectroscopy. (wikipedia.org)

This has led to many surprising discoveries, such as multiple spin echoes and intermolecular cross-peaks in 2D spectroscopy. (copernicus.org)

This spectroscopy is based on the measurement of absorption of electromagnetic radiations in the radio frequency region from roughly 4 to 900 MHz. (wikipedia.org)

Anatomy12

Organisms3

Diseases7

Chemicals and Drugs66

Analytical, Diagnostic and Therapeutic Techniques and Equipment49

Psychiatry and Psychology3

Phenomena and Processes46

Disciplines and Occupations6

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture2

Information Science11

Health Care8

Exchange spectroscopy3

Correlation3

Solid-state NMR spectr1

Atomic nuclei4

Homonuclear and heteronuclear1

Dipolar3

Multi-dimensional2

Experiments6

Nuclear Overha1

Dynamics5

Pulses2

20211

Relaxation1

Characterization4

Spectra8

HSQC1

Sequences2

Experimental2

Nuclei5

Spectroscopic1

Chemistry8

Polarization2

HRMAS1

Quantum2

Spectrometers3

Computational1

Biomolecules1

Shift3

Molecule5

Pulse2

Solvent1

Chemical2

Gradients1

Magnetization1

Metabolism1

20231

Metabolomics1

Journal4

Elucidation1

Protein1

Processes1

Frequencies2

Transition1

Intermolecular1

Measurement1