Fetus prenatal exposure delayed effects. Medical search. Frequent questions

In Wistar rats, maternal exposure to nicotine was shown to impair the inhibitory function of perivascular adipose tissue on vascular contractility in the aorta of the offspring. (mcmaster.ca)
Two major types of NAS are recognized: NAS due to prenatal or maternal use of substances that result in withdrawal symptoms in the newborn and postnatal NAS secondary to discontinuation of medications such as fentanyl or morphine used for pain therapy in the newborn. (medscape.com)
[ 3 , 4 ] This article focuses on prenatal or maternal use of licit or illicit drugs, although symptoms and therapy for postnatal NAS are similar. (medscape.com)
Maternal substance abuse, the cause of prenatal NAS, is a leading preventable cause of mental, physical, and psychological problems in infants and children. (medscape.com)
Maternal exposure to SHS during pregnancy may result in delayed MDI in early childhood. (biomedcentral.com)
The effects of gestational exposure to atrazine in rats and rabbits include increased post-implantation losses, full-litter resorptions, decreased live fetuses/litters, increased prenatal loss, decreased litter size, and reduced pup weights, which could be attributed to severe maternal toxicity. (weedkiller.news)
The impact of maternal depression on the fetus. (psychiatrictimes.com)
Despite, or perhaps because of, heightened attention to the use of antidepressants during pregnancy over the past decade, the management of prenatal maternal depression has become increasingly controversial. (psychiatrictimes.com)
Clinical decision making must consider the well-being of the mother, fetus, and even older children who can be adversely impacted by active maternal psychopathology. (psychiatrictimes.com)
The relative risk of fetal exposure to maternal depression versus that of antidepressant medication remains poorly defined because of our reliance on a patchwork conglomeration of case series, pregnancy registries, and observational studies with inconsistent levels of control for potentially confounding exposures. (psychiatrictimes.com)
and (3) the impact of untreated maternal prenatal depression on the well-being of offspring. (psychiatrictimes.com)
The prenatal treatment should follow the standard treatment as much as possible to optimize the maternal prognosis, always taking into account the fetal well-being. (medichub.ro)
Ross and colleagues suggest that pre- and post-natal choline supplementation may be able to reverse the effects of maternal anxiety on infants. (bipolarnews.org)
[ 1 , 2 ] This article focuses on prenatal or maternal use of illicit drugs, although symptoms and therapy for postnatal neonatal abstinence syndrome are similar. (medscape.com)
The current study examined associations of mindfulness facets during pregnancy with toddler's social-emotional development and behavior problems, as well as potentially mediating effects of maternal mental health. (researchgate.net)
Pregnancy distress mediated the association between maternal non-judging skills during pregnancy and child externalizing problem behavior, but no other mediating effects were found. (researchgate.net)
The scope of the problem, the pathophysiology of tobacco use in pregnancy, and clinical effects of cigarette smoking on maternal, fetal, and neonatal outcomes will be reviewed here. (medilib.ir)
The aim of this study was to investigate the maternal attitude towards the vulnerability of the developing fetus to cell phone radiation, and some related factors among women admitted to AL-Zahra Hospital. (brieflands.com)
Delayed growth is evaluated with multivessel Doppler testing by a maternal-fetal medicine specialist. (msdmanuals.com)

While the effect of this force is not fully understood, research suggests that it may change cell permeability and have adverse effects on both early and late prenatal and postnatal development. (thehealthyskeptic.org)
In dermal Segment I and III studies with Gelec (Ammonium Chloride) lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m 2 /day), approximately 0.4 times the human topical dose. (sdrugs.com)

Certain reproductive effects in fertility, growth, and development for males and females have been linked specifically to OP pesticide exposure. (wikipedia.org)
In females menstrual cycle disturbances, longer pregnancies, spontaneous abortions, stillbirths, and some developmental effects in offspring have been linked to OP pesticide exposure. (wikipedia.org)
Farm couples living year-round on farms in Ontario, Canada did not have altered sex ratios, and the risk of small for gestational age deliveries was not increased in relation to pesticide exposure. (cdc.gov)
for Economic Cooperation and Development, pesticide exposure. (cdc.gov)

Neurotoxic effects have also been linked to poisoning with OP pesticides causing four neurotoxic effects in humans: cholinergic syndrome, intermediate syndrome, organophosphate-induced delayed polyneuropathy (OPIDP), and chronic organophosphate-induced neuropsychiatric disorder (COPIND). (wikipedia.org)
Data regarding the health effects of atrazine in humans are limited to ecological, case-control, and cohort mortality cancer studies and reproductive/ developmental toxicity studies. (cdc.gov)
The study noted that "some of the specific effects observed in animals are "not likely to occur in humans" because of biological differences between the two. (weedkiller.news)
Atrazine exposure has been associated with developmental effects in both humans and animals. (weedkiller.news)
According to US National Institutes of Health (NIH), in humans, the term "embryo" applies to a fertilized egg from the beginning of division up to the end of the eighth week of gestation, when the embryo becomes a fetus. (asu.edu)
The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. (sdrugs.com)
In absence of data to the contrary, assume that the toxicokinetics is the same in animals and humans under similar exposure conditions. (cdc.gov)
Animals that have similar toxicokinetics to humans likely serve as good predictors of harmful effects in humans. (cdc.gov)
Understanding the basic or specific biologic changes that ultimately lead to clinical disease in a test animal can help health assessors determine how well animal models might predict the similar adverse effect in humans. (cdc.gov)
Public health officials and others concerned with appropriate actions to take at hazardous waste sites may want information on levels of exposure associated with more subtle effects in humans or animals (LOAELs) or exposure levels below which no adverse effects (NOAELs) have been observed. (cdc.gov)
Findings of adverse effects in any one species do not necessarily indicate such effects might be generated in humans. (fluoridealert.org)
From a conservative risk assessment perspective however, adverse findings in animal species are assumed to represent potential effects in humans, unless convincing evidence of species specificity is available. (fluoridealert.org)
Data demonstrated that humans are less sensitive to the effect that causes developmental toxicity in rabbits and the PBPK model incorporated this information, resulting in a higher HEC for the developmental endpoint than for the nasal endpoint. (cdc.gov)

We conclude that fetal and neonatal exposure to nicotine caused blood pressure elevation. (mcmaster.ca)
Primary treatment of neonatal symptoms related to prenatal substance exposure should be supportive because pharmacologic therapy can prolong hospitalization and exposes the infant to additional agents that are often not necessary. (medscape.com)
Similar to previous studies, technical grade dinocap caused cleft palate and weight deficits in fetuses at term and increased neonatal mortality and abnormal swimming behavior, torticollis, and deficient otolith formation in surviving pups. (epa.gov)
Postnatal neonatal abstinence syndrome results when an abrupt discontinuation of opioid analgesia occurs, usually after prolonged drug exposure. (medscape.com)
A study was made of electrocardiographic changes in 3 and 6 week old rats exposed in-utero to ethylene - glycol -monomethyl-ether (109864) (EGME) in order to determine if intraventricular conduction delays previously observed in fetuses would persist beyond the fetal/neonatal period. (cdc.gov)
See 'Neonatal effects' below. (medilib.ir)
Disability may be developmental or acquired and may arise from prenatal damage, perinatal factors, acquired neonatal factors and early childhood factors. (who.int)

To ensure the optimal treatment for both mother and fetus, a multidisciplinary team of specialists should be involved in the decision-making. (medichub.ro)
Secondly, fish is an important source of lean protein, which is vital for the growth and repair of cells, tissues, and muscles in both the mother and fetus. (fishtankfacts.com)
While fish is an excellent source of essential nutrients for both mother and fetus, it is important to ensure that the type of fish consumed is not high in mercury or other environmental contaminants. (fishtankfacts.com)
Educate patients and partners about the consequences of tobacco use for both mother and fetus. (medilib.ir)

Placental passage of these environmental toxicants might affect prenatal nervous system development. (biomedcentral.com)
Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. (aahd.us)
Prenatal exposure to toxicants : developmental consequences / edited by Herbert L. Needleman and David Bellinger. (who.int)

Therefore, more attention should be paid to pregnant women and infants who are susceptible to SHS exposure. (biomedcentral.com)
This includes implementing regulations and guidelines for the cannabis industry, enhancing access to prenatal care and substance use treatment programs, and ensuring that healthcare providers are equipped with the knowledge and resources to address the specific needs of pregnant women using cannabis. (timebusinesstoday.com)
Unfortunately, many pregnant women are unaware of the influence of alcohol on the fetus during pregnancy," Kienast said in a 22 November RSNA statement. (auntminnieeurope.com)
Pregnant women exposed to anxiety throughout her pregnancy is exposed to greater risks of preterm birth as well as a delayed prenatal growth rate. (wowessays.com)
All six cases were in foreign-born pregnant women assessed for lead exposure risk by health-care providers during prenatal visits, as required by New York state law. (cdc.gov)
The six patients in this report all were asymptomatic pregnant women whose health-care providers assessed them to be at risk for lead exposure. (cdc.gov)
In pregnant women, exposure of the fetus to the anticonvulsant valproate (VPA or Depakote) is associated with a variety of serious problems that include congenital malformations, developmental delay, and autism. (bipolarnews.org)
In conclusion, the question of whether pregnant women can eat fish is critical to the healthy growth and development of the fetus. (fishtankfacts.com)
The Centers for Disease Control and Prevention found that, despite warning labels on alcoholic beverages that indicate possible adverse effects on prenatal development, 1 in 10 pregnant women report alcohol use and more than 3 million women in the USA are at risk of exposing their developing fetus to alcohol [ 9 ]. (biomedcentral.com)
According to the literature, pregnant women are at increased risk of such adverse health effects ( 2 ), particularly regarding the sensitivity of early embryos to environmental exposures ( 3 ), which is similar to general anesthetics-related neurotoxicity in developing the brain during pregnancy ( 4 - 8 ). (brieflands.com)
[ 4 ] Unfortunately, it has been reported that 30% of pregnant women are not tested for HIV during pregnancy, and another 15-20% receive no or minimal prenatal care, thereby allowing for potential newborn transmission. (medscape.com)
Pregnant women should delay travel to areas where Zika is spreading. (cdc.gov)

Tetrahydrocannabinol (THC), the psychoactive compound in cannabis, can cross the placenta and affect the developing fetus. (timebusinesstoday.com)
The imaging diagnostic methods can have te-ra-to-genic effects on the fetus, especially in the first tri-mes-ter of pregnancy, and the oncological treatment can have an impact on fetal growth, the neurological and car-dio-vas-cu-lar system, and it is known that cytostatics cross the placenta in large quantities. (medichub.ro)

Indeed, the conventional package label warning that use in pregnancy is not recommended unless the potential benefits justify the potential risks to the fetus is impossible to follow unless the risks of both antidepressant therapy and treatment discontinuation are understood. (psychiatrictimes.com)
Also, 64.3% believed that cell phone use poses risks to the fetus, while 26.7% had no idea. (brieflands.com)

Evidence of OP exposure in pregnant mothers are linked to several health effects in the fetus. (wikipedia.org)
We explored the association between prenatal exposure to SHS and neurodevelopment at 24 months of age considering genetic polymorphism and breastfeeding in 720 mothers and their offspring enrolled in the Korean multicenter birth cohort study (Mothers and Children Environmental Health, MOCEH). (biomedcentral.com)
We quantified urine cotinine concentrations in mothers once from 12th to 20th gestational weeks and excluded those whose urine cotinine levels exceeded 42.7 ng/ml to represent SHS exposure in early pregnancy. (biomedcentral.com)
Furthermore, because mercury was also discovered in the breast milk of the mothers, the babies' exposure continued after birth. (medscape.com)
In the last article in this series on natural childbirth, I reviewed evidence suggesting that routine prenatal ultrasound does not improve birth outcomes for mothers or babies, and that organizations like the American College of Obstetricians & Gynecologists recommend ultrasound scans only for specific reasons. (thehealthyskeptic.org)
Liggins also discovered that cortisol given to pregnant mothers helped delay premature labor, and that it increased the likelihood that premature infants would breathe normally after birth. (asu.edu)
Infants of mothers who used street drugs had a greater delay in neuropsychomotor development. (bvsalud.org)

Left) Fetal brain post-intrauterine alcohol exposure in a fetus between 25 and 29 gestational weeks. (auntminnieeurope.com)
This was true even for fetuses with mild alcohol exposure. (auntminnieeurope.com)
Drosophila melanogaster is an excellent model to study the genetic basis of the effects of developmental alcohol exposure since many individuals of the same genotype can be reared under controlled environmental conditions. (biomedcentral.com)
We reared DGRP lines which showed extreme upregulation or downregulation of snoRNA expression during developmental alcohol exposure on standard or ethanol supplemented medium and demonstrated that developmental exposure to ethanol has genotype-specific effects on adult locomotor activity and sleep. (biomedcentral.com)
Although defects from prenatal alcohol exposure can be replicated in mouse models [ 10 ], identifying genetic factors that contribute to susceptibility to FASD is virtually impossible in human populations since time, dose, and frequency of exposure are generally unknown, and manifestations of FASD are diverse and become evident long after exposure. (biomedcentral.com)
Drosophila melanogaster presents an advantageous model for studies on the genetic underpinnings associated with symptoms of developmental alcohol exposure. (biomedcentral.com)

1) thermal rather than nonthermal mechanisms are more likely to induce adverse effects in utero, and (2) while the probability of an adverse thermal event is usually small, under some conditions it can be disturbingly high. (thehealthyskeptic.org)
Developmental delay resulting from valproate exposure can cause an average loss of 9 IQ points compared to children exposed to other anticonvulsant drugs in utero . (bipolarnews.org)
The clearest example of a disruptor is diethylstilbestrol (DES), a chemical that behaves like a hormone and not only affects the health of the exposed person, but also can generate irreversible damage to their descendants since the exposure of a mother to these compounds during pregnancy can generate varied and unexpected effects on the offspring several decades after having been exposed in utero. (ivis.org)

Developmental effects have been observed following pre-gestational, gestational, and lactational exposure of rat and rabbit dams or post-weaning exposure of rat pups to atrazine. (cdc.gov)
Studies have shown that gestational and peripubertal exposure to atrazine has an effect on reproductive development in rats and rabbits. (weedkiller.news)
Right) Brain of matched healthy control case in a fetus between 25 and 28 gestational weeks. (auntminnieeurope.com)
The researchers conducted a study that included MRI exams of 24 fetuses between 22 and 36 gestational weeks who were exposed to alcohol, matching each with 20 control cases of fetuses who had not been exposed to alcohol. (auntminnieeurope.com)
In a study of the effect on infant health of a mother's experience of adversity in childhood by researcher Deborah Kim and colleagues, both adversity in childhood (such as physical abuse or the loss of a parent) and stress during pregnancy were associated with low infant birth weight and lower gestational age at birth . (bipolarnews.org)

The onset and severity of symptoms, whether acute or chronic, depends upon the specific chemical, the route of exposure (skin, lungs, or GI tract), the dose, and the individuals ability to degrade the compound, which the PON1 enzyme level will affect. (wikipedia.org)
The effects appear to be in part dose-related and dependent on the intensity of combination treatment with other agents. (bipolarnews.org)
There was a dose related effect of EGME on pup survival, with 100 percent mortality after day one in the 75mg/kg group and about 50 percent mortality by day three in the 50mg/kg group. (cdc.gov)
Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively and have revealed no evidence of impaired fertility or harm to the fetus due to Gelec (Ammonium Chloride) lactate formulations. (sdrugs.com)
A contaminant will produce adverse or toxic effects only if it (or its metabolites) reaches specific sites in the body at a dose and over a duration sufficient to produce an adverse non-cancer effect. (cdc.gov)
Model inputs include the exposure dose and model parameters, such as tissue volumes, blood flow rates, partition coefficients, and metabolic rates. (cdc.gov)
Identifying genetic risk alleles for FASD is challenging since time, dose, and frequency of exposure are often unknown, and manifestations of FASD are diverse and evident long after exposure. (biomedcentral.com)
LOAELs or NOAELs should also help in determining whether or not the effects vary with dose and/or duration, and place into perspective the possible significance of these effects to human health. (cdc.gov)
The risk of irreversible neurological damage depends on the dose received by the fetus, and the duration of the exposure period. (safoceanindien.org)
The model enabled calculation of human equivalent con- centrations (HECs) to the animal no-observed-adverse-effect levels (NOAELs) using chemical-specific parameters to determine the internal dose instead of default assumptions. (cdc.gov)

As a result of exposure to this radiation-emitting technology, children are at great risk of mutated genetic development, neurodevelopmental delays, brain damage that can contribute to autism and reproductive effects that can lead to sterility. (activistpost.com)
Thimerosal has historically been used in multidose vaccine vials and medical products to inhibit fungal and bacterial contaminations, yet due to concerns regarding potential links to neurodevelopmental disorders like autism as well as toxic side effects, several nations have restricted or drastically decreased its usage within vaccines and medical products. (ablogwithadifference.com)
Commenting on speech delays that present in the context of "complex neurodevelopmental disorders," one researcher notes that "The term complex …is used to include environmental contributions to neurodevelopmental disorders" [emphasis in original]. (namelyliberty.com)
prenatal exposure to methylmercury (via industrial releases in Minimata Bay, Japan) led to serious neurodevelopmental delays in children, with language dysfunction being one of the prominent symptoms observed. (namelyliberty.com)
This research includes past studies of Minimata disease, which showed that prenatal exposure to methylmercury (via industrial releases in Minimata Bay, Japan) led to serious neurodevelopmental delays in children, with language dysfunction being one of the prominent symptoms observed. (namelyliberty.com)

It is well known that SHS exposure brings about almost the same adverse health outcomes as active smoking [ 3 ]. (biomedcentral.com)
Research suggests that prenatal cannabis exposure may lead to adverse outcomes, including low birth weight, preterm birth, developmental delays, and cognitive impairments. (timebusinesstoday.com)
Additionally, smoking cannabis exposes both the mother and the fetus to harmful chemicals, similar to tobacco smoke, further increasing the risk of adverse outcomes. (timebusinesstoday.com)
This analysis suggests that adverse cognitive and behavioral outcomes may be related to lead's effect on brain development producing persistent alterations in structure. (aahd.us)

BACKGROUND: Although environmental lead exposure is associated with significant deficits in cognition, executive functions, social behaviors, and motor abilities, the neuroanatomical basis for these impairments remains poorly understood. (aahd.us)

Here we studied the blood pressure effects and the alteration of perivascular adipose tissue function in mesenteric arteries of the offspring born to Wistar-Kyoto rat (WKY) dams exposed to nicotine. (mcmaster.ca)
In mesenteric arteries from control offspring, contractile responses induced by phenylephrine, serotonin, and 9,11-dideoxy-11alpha, 9alpha-epoxymethanoprostaglandin F(2)alpha (U44619) were significantly attenuated in the presence of perivascular adipose tissue, an effect not observed in the nicotine-exposed tissues. (mcmaster.ca)

Harmful exposure to these environmental risks could begin in the mother's womb and affect fetal development. (biomedcentral.com)

Mercury is a toxic element that can accumulate in fish and is associated with developmental brain damage in fetuses. (fishtankfacts.com)

These syndromes result after acute and chronic exposure to OP pesticides. (wikipedia.org)
These data are discussed in terms of three exposure periods: acute (14 days or less), intermediate (15-364 days), and chronic (365 days or more). (cdc.gov)
Serious' effects are those that evoke failure in a biological system and can lead to morbidity or mortality (e.g., acute respiratory distress or death). (cdc.gov)
Toxicology deals with acute illnesses caused by high levels of exposure to relatively rare toxins with little emphasis on developmental impacts, carcinogenicity, or the ambient sources of toxins. (tessmed.com)
The critical effects of acute duration iodomethane exposure are: (1) fetal losses in rabbits, (2) lesions in rat nasal epithelium, and (3) transient neurotoxicity in rats. (cdc.gov)
Iodomethane HECs for workers and bystanders were derived using the PBPK model and NOAELs for acute exposure endpoints of concern. (cdc.gov)
Nasal olfactory degeneration is the primary endpoint for risk assessment of acute exposure to iodomethane. (cdc.gov)

The use of street drugs during pregnancy, due to their deleterious effects on the health of the infant, may have clinical implications for neuropsychomotor development. (bvsalud.org)
Due to their deleterious effects on infant health, these drugs may still have clinical implications for neuropsychomotor development, as well as the social and economic impact on health 6 . (bvsalud.org)

With the increase of the rate of diagnosis and specific oncological treatment, there were registered changes in the obstetrical behavior, but certain side effects were also observed on the fetus and the newborn. (medichub.ro)
The oncological pathology during pregnancy remains a chal-lenge, due to the side effects of diagnostic methods and treat-ment on the pregnant woman, on the fetus and later on the newborn. (medichub.ro)
Because the effects on the fetus and newborn, in the short term, after cancer treatment, are soothing, more women receive treatment during pregnancy. (medichub.ro)

MATERIALS AND METHODS: The nephroprotective effect of SF-SBM was investigated using both an HEK-293 cell line and Wistar rats. (bvsalud.org)
Atrazine exposure in rats is also associated with delayed vaginal opening, first estrus cycle, and uterine growth for female rats and decreased prostate weight, increased incidence and severity of inflammation of the lateral prostate, increased myeloperoxidase levels in the prostate, and increased total DNA in the prostate for male rats. (weedkiller.news)
Chronic exposure of rats resulted in increased thyroid follicular cell tumors from sustained perturbation of thyroid hormone homeostasis. (cdc.gov)

The effects of OP exposure on infants and children are at this time currently being researched to come to a conclusive finding. (wikipedia.org)

A visit with an obstetric health care provider also should be a part of the pretravel assessment to ensure routine prenatal care and identify any potential problems. (cdc.gov)
For visits not related to your routine pregnancy visits, (described in the prenatal section of FAQ ), please always contact the office to schedule. (womensobgyncare.com)

Re-gar-ding the medical decisions for the pregnancies of on-co-lo-gi-cal patients, the safety of the fetus, the risk of me-tas-ta-sis and the viability of the fetus must be taken into account. (medichub.ro)
Unfortunately, there are situa-tions in which fetal and placental metastases are en-coun-tered and these will negatively influence the viability of the fetus. (medichub.ro)

The information you will need during this part of the PHA process will vary by the contaminants of concern, site-specific exposures, and particular concerns related to the site. (cdc.gov)

When the general population is exposed to atrazine, exposure levels are expected to be very low. (cdc.gov)
The primary adverse health effects of atrazine exposure are reproductive/developmental effects following inhalation, oral, and dermal exposure. (cdc.gov)

The evolution of fetuses and newborns is generally favorable in the short term, but in the long term there are not enough studies to draw a conclusion. (medichub.ro)

This effect might be modified by genetic polymorphism and breastfeeding behavior. (biomedcentral.com)
Whether an exposure could lead to an adverse health outcome depends on the characteristics of exposure and the exposed population (e.g., developmental stage, existing disease state, genetic factors) that could make them more susceptible to site-related exposures. (cdc.gov)
There is significant and sex-specific natural genetic variation in the transcriptional response to developmental exposure to ethanol in Drosophila that comprises networks of genes affecting nervous system development and ethanol metabolism as well as networks of regulatory non-coding RNAs. (biomedcentral.com)
Major depression seems to be a more frequent co- Furthermore, obstetric care providers often lack the ability to morbid antecedent diagnosis in women who develop addic- effectively screen their patients for substance abuse,2,3 and tion disorders than in men.13 The depression seems to be the negative attitudes toward these patients frequently limit their result of sex-specific genetic and environmental factors and access to adequate prenatal care. (nomedicalcare.com)
These may include genetic factors, infections, traumatic or toxic exposure or nutritional factors which result in perinatal or postnatal damage. (who.int)

toxic effects [of alcohol on prenatal] brain development opens new diagnostic opportunities for fetal neuroradiology, allowing early postnatal support programs in these cases and stimulating the discussion of alcohol prevention during pregnancy to promote public health," the group noted. (auntminnieeurope.com)
No unusual toxic effects were reported. (sdrugs.com)
The use of high doses increases the likelihood that potentially significant toxic effects will be identified. (fluoridealert.org)

The use of street drugs during pregnancy can be devastating, since in some cases it results in irreversible consequences to the mother-fetus binomial 5 . (bvsalud.org)
As elsewhere, the denial and the taboos of female alcoholism, coupled with ignorance of the consequences of prenatal alcohol on the child, do not allow collective awareness and the implementation of a prevention policy effective. (safoceanindien.org)

[ 2 ] Chronic opioid exposure in the most common source of NAS. (medscape.com)
It was during the 1800s that the phrase "mad as a hatter" was coined, owing to the effects of chronic mercury exposure in the hat-making industry, where the metal was used in the manufacturing process. (medscape.com)

The mechanisms by which cannabis use during pregnancy can harm the developing fetus are still being studied. (timebusinesstoday.com)
Absolute contraindications are conditions for which the potential harm of travel during pregnancy always outweighs the benefits of travel to the pregnant person or fetus. (cdc.gov)
The overwhelming number of chemicals to which we are now exposed and the pervasive nature of that exposure makes differentiating between the dangerous and the benign a painstaking process because chemicals don't necessarily have to be present in large amounts to produce harm, and the harm they do create might not be immediate. (tessmed.com)

Prenatal exposures also elevated risks for symptoms or diagnoses of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). (rebeccagenuis.com)

Prenatal alcohol (ethanol) exposure can have dramatic effects on the development of the central nervous system (CNS), including morphological abnormalities and an overall reduction in white matter of the brain. (asu.edu)
Prenatal exposure to ethanol can cause fetal alcohol spectrum disorder (FASD), a prevalent, preventable pediatric disorder. (biomedcentral.com)

The bulk of the available toxicity data is from oral exposure studies in animals. (cdc.gov)
If alcohol is particularly harmful during the period of organogenesis, ie during the first trimester of pregnancy, toxicity is exercised throughout pregnancy, and resounding on the overall growth of the fetus as well as brain development, the brain being the most vulnerable organ of the body. (safoceanindien.org)

A quantitative human health risk assessment was conducted for inhalation exposure. (cdc.gov)

Also, in the so-called DES-sons abnormalities were found, mainly, the presence of Müllerian duct remnants, which indicates that fetal exposure to DES may have an effect on male sex differentiation . (diethylstilbestrol.co.uk)

Ethylmercury exposure typically comes through using thimerosal, an organic compound which contains high concentrations of the substance, in various industries and products, where its use poses risks of exposure. (ablogwithadifference.com)
The various medical and obstetric complications unique to this Significant differences exist between men and women patient population will be discussed as well as the specific adverse who are affected by addiction disorders with respect to the effects of substance abuse on placentation and the developing fetus. (nomedicalcare.com)
See "Substance use during pregnancy: Screening and prenatal care" . (medilib.ir)

The topical treatment of CD-1 mice with 12%, 21% or 30% Gelec lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. (sdrugs.com)

This video covers the dangers of ultrasound and the exposure to the developing fetus. (activistpost.com)
This book offers a ground-breaking analysis of the documented facts concerning prenatal ultrasound. (activistpost.com)
Nevertheless, within the many pages of this book, you will find nearly 300 pages of sourced material, plus 1300 citations to confirm that prenatal ultrasound is harming children and should be banned from obstetrics immediately. (activistpost.com)
Pregnant military wives used as testers for X-rays on their fetuses - what level didn't kill the unborn child - then calling it ultrasound. (activistpost.com)
Though both animal and human studies have shown that temperature elevations can cause abnormal development and birth defects, so far human studies have not shown a direct causal relationship between diagnostic ultrasound exposure during pregnancy and adverse effects to the developing baby. (thehealthyskeptic.org)
This means we have no large, population-based studies examining the effects of ultrasound at the much higher intensities commonly used today . (thehealthyskeptic.org)
The risk of inducing thermal effects is greater in the second and third trimesters, when fetal bone is intercepted by the ultrasound beam and significant temperature increase can occur in the fetal brain. (thehealthyskeptic.org)
Ian Donald said he would not use antenatal ultrasound before three months gestation, but now all embryos are routinely scanned and there is no data on safety, including possible effects on miscarriage rates. (midwiferytoday.com)

These complications may include adverse effects on fetal development, pregnancy complications, and other related health concerns. (timebusinesstoday.com)

Most of the research on reproductive effects has been conducted on farmers working with pesticides and insecticides in rural areas. (wikipedia.org)
Reproductive NOEL = 100 mg/kg/day (There were no treatment-related reproductive effects in either sex. (fluoridealert.org)

Objectives During the perinatal period, women are exposed to major changes, holding possible adverse effects on psychological well-being and child development. (researchgate.net)

The authors conclude that doses of EGME that are not maternally toxic have a severe effect on reproductive outcome, producing an intraventricular conduction delay that persists through at least 6 weeks of age. (cdc.gov)
The points in the figures showing no-observed-adverse-effect levels (NOAELs) or lowest- observed-adverse-effect levels (LOAELs) reflect the actual doses (levels of exposure) used in the studies. (cdc.gov)

Therefore, SHS exposure should be considered a modifiable risk factor for delayed neurodevelopment and cognitive impairment in children. (biomedcentral.com)
Exercise can delay or reduce the risks for the development of dementia in the aging population thereby improving cognitive performance with age. (wowessays.com)

Prenatal exposure has been linked to impaired fetal growth and development. (wikipedia.org)
Fetal exposure to lead can adversely affect neurodevelopment, decrease fetal growth, and increase the risk for premature birth and miscarriage ( 1 ). (cdc.gov)

BACKGROUND: Out of all measure systemic exposure to fluorides can cause defect of skeletal and dental fluorosis. (bvsalud.org)

Alcohol use during pregnancy exposes fetuses to fetal alcohol spectrum disorders, which can cause learning disabilities, behavioral problems, or speech and language delays, according to the investigators. (auntminnieeurope.com)

Public health professionals should consider these types of products when investigating heavy metal exposures and raise awareness among health-care providers and the public regarding the health risks posed by such products. (cdc.gov)
If they become pregnant, prenatal care should begin as early as possible. (msdmanuals.com)

This information, along with data on ZDV efficacy in preventing perinatal transmission (3) and evidence that PEP prevented or ameliorated retroviral infection in some studies in animals (4), prompted a Public Health Service (PHS) interagency working group *, with expert consultation (5), in June 1996 to issue provisional recommendations for PEP for HCWs after occupational HIV exposure (6). (cdc.gov)

However, the knowledge about the effects of narghile smoke on health is partial and sometimes contradictory. (who.int)
The second part highlights the lack of reliable data about the detrimental effects of the narghile pipe on health and especially on the cardiopulmonary function. (who.int)
Exposure to active smoking and secondhand smoke (SHS) causes health concern. (biomedcentral.com)
Health Effects Research Lab. (epa.gov)
It is a global treaty to protect human health and the environment from the adverse effects of mercury. (medscape.com)
Here we explore their differences, exposure sources, as well as any health-related concerns they could present on this page. (ablogwithadifference.com)
Both forms are organic mercury forms but their chemical structures, exposure sources, health risks, and evaluation considerations differ - leading to different health concerns when considering risk. (ablogwithadifference.com)
While mercury exposure from using products containing thimerosal may occur, generally speaking the levels are low and do not pose significant health risks to users. (ablogwithadifference.com)
several medications also contained mercury or arsenic, which also can have adverse health effects. (cdc.gov)
Men play a substantial role in prenatal health. (susansmithjones.com)
Effect of prenatal exposure to diethylstilbestrol on Müllerian duct development in fetal male mice, US National Library of Medicine National Institutes of Health, Endocrinology, NCBI PubMed PMID: 9751506 , 1998 Oct. (diethylstilbestrol.co.uk)
Editor's Note: This research shows that a mother's health and earlier life stressors could have an adverse effect on her child. (bipolarnews.org)
This section provides an overview of how to examine factors that influence whether an exposure to a contaminant could produce harmful health effects and how these factors weigh into your public health conclusions. (cdc.gov)
As depicted in the figure below, multiple factors influence whether an exposure could result in harmful health effects, as well as the type and severity of those health effects. (cdc.gov)
When available, health assessors can refer to the toxicokinetic data analysis included in the MRL summary in the Toxicological Profile, which presents methods for extrapolating animal data to human exposure. (cdc.gov)
For example, EPA's IEUBK Model external icon is a type of PBPK model that ATSDR health assessors should use when evaluating childhood exposure to lead in soil. (cdc.gov)
The distinction between 'less serious' effects and 'serious' effects is considered to be important because it helps the users of the profiles to identify levels of exposure at which major health effects start to appear. (cdc.gov)
We have no data on alcoholism in the Indian Ocean, and if the mental impact is of 3% in Reunion Island (Reunion Island is the first French region in terms of the effects of alcoholism on Mental Health) they are 3.2% in Mauritius. (safoceanindien.org)
Failure to enact Clear Skies this year will delay important public health and environmental benefits. (epa.gov)
A physiologically based pharmacokinetic (PBPK) model for iodomethane was developed to characterize poten- tial human health effects from iodomethane exposure. (cdc.gov)
Iodomethane is a new agricultural of approximately 24 hours due to the emission patterns of active ingredient, and there are no human exposure incident the compound and air dispersion patterns ( EPA OPP Health reports related to agricultural uses. (cdc.gov)

Despite the lack of conclusive and proven supporting epidemiologic data about the association between cell phone radiofrequency electromagnetic fields (RF-EMF) and the developing fetus complications, there are frequent discussions about this matter. (brieflands.com)
While problems related to these exposures may not appear after birth, the possibility of long-term complications has always been raised. (brieflands.com)

Secondhand tobacco smoke (SHS) exposure of children and their families causes significant morbidity and mortality. (who.int)
In their personal and professional roles, pediatricians have many opportunities to advocate for elimination of SHS exposure of children, to counsel tobacco users to quit, and to counsel children never to start. (who.int)
However, a growing subset of American children suffers from speech delays or other language difficulties that are cheating families out of sharing these exciting milestones and the children of their potential for a full and productive life. (namelyliberty.com)
It is estimated that in industrialized countries, 1-3 in 1000 children are suffering from Fetal Alcohol Syndrome (FAS) at birth, while the percentage of children affected by the effects of alcohol on the fetus (FAE) (learning difficulties and social integration) could be much higher, around 10 per 1000 births. (safoceanindien.org)
Accidental exposure to fentanyl transdermal system, especially in children, can result in fatal overdose of fentanyl. (nih.gov)

Measure of cotinine in hair, blood, and urine permits the assessment of SHS exposure or active smoking. (biomedcentral.com)
Similarly, destruction of neonatally abundant pluripotent stem cells would likely have a more pervasive outcome than destruction of The value of incorporating immunologic appeared more severe and/or persistent when single lineages or differentiated cells that pre- data for the toxicologic assessment of drugs, the exposure occurred perinatally when com- dominate in adults. (cdc.gov)

If sun exposure is unavoidable, clothing should be worn to protect the skin. (sdrugs.com)

In 1889, Charcot, in his Clinical Lectures on Diseases of the Nervous System, attributed some rapid oscillatory tremors to mercury exposure. (medscape.com)
This happens because the drug can overcome the placental and blood-brain barrier, without previous metabolism, acting mainly on the central nervous system of the fetus. (bvsalud.org)

There is no consensus on the significance of cavitation effects in human fetal tissue, but some evidence suggests that mammalian tissue may contain microbubbles that are susceptible to cavitation effects. (thehealthyskeptic.org)

Levels of significant exposure for each route and duration are presented in tables and illustrated in figures. (cdc.gov)

Some of these effects include delayed mental development, Pervasive developmental disorder (PDD), morphological abnormalities in the cerebral surface. (wikipedia.org)
Other considerations include pregnancy in the HCW and exposure to virus known or suspected to be resistant to antiretroviral drugs. (cdc.gov)
Recommendations for PEP have been modified to include a basic 4-week regimen of two drugs (zidovudine and lamivudine) for most HIV exposures and an expanded regimen that includes the addition of a protease inhibitor (indinavir or nelfinavir) for HIV exposures that pose an increased risk for transmission or where resistance to one or more of the antiretroviral agents recommended for PEP is known or suspected. (cdc.gov)
The major congenital malformations that can result from valproate exposure include spina bifida, which results in lifelong paralysis of the child's lower limbs. (bipolarnews.org)
Other potential effects include a small increase in miscarriage risk and a possible increase in some congenital malformations. (medilib.ir)

The decision to recommend HIV postexposure prophylaxis must take into account the nature of the exposure (e.g., needlestick or potentially infectious fluid that comes in contact with a mucous membrane) and the amount of blood or body fluid involved in the exposure. (cdc.gov)

Anatomy16

Organisms10

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Chemicals and Drugs55

Analytical, Diagnostic and Therapeutic Techniques and Equipment39

Psychiatry and Psychology29

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Humans13

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Utero3

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Mother's womb1

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Acute7

Deleterious effects2

Newborn3

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Potentially1