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  • Studies have shown that cardiomyocytes derived from ES are validated in vitro models to test drug responses and predict toxicity profiles. (wikipedia.org)
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  • In his 1995 encyclical Evangelium Vitae , John Paul said, "This moral condemnation also regards procedures that exploit living human embryos and fetuses - sometimes 'produced' for this purpose by in vitro fertilization - either to be used as 'biological material' or as providers of organs or tissue for transplants in the treatment of certain diseases. (ncregister.com)
  • Because Embryonic Stem (ES) cells are cultured from the embryoblast 4-5 days after fertilization, harvesting them is most often done from donated embryos from in vitro fertilization (IVF) clinics. (wikipedia.org)
  • France prohibits reproductive cloning and embryo creation for research purposes, but enacted laws (with a sunset provision expiring in 2009) to allow scientists to conduct stem cell research on imported a large amount of embryos from in vitro fertilization treatments. (wikipedia.org)
  • In 2001, the British Parliament amended the Human Fertilisation and Embryology Act 1990 (since amended by the Human Fertilisation and Embryology Act 2008) to permit the destruction of embryos for hESC harvests but only if the research satisfies one of the following requirements: Increases knowledge about the development of embryos, Increases knowledge about serious disease, or Enables any such knowledge to be applied in developing treatments for serious disease. (wikipedia.org)
  • Embryos from rescued in vitro-matured metaphase II (IVM-MII) oocytes show significantly higher fertilization rates and more blastomeres per embryo compared with those from arrested metaphase I (MI) oocytes (58.5% vs. 43.9% and 5.7 vs. 5.0, respectively). (wikipedia.org)
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  • However, in vitro studies with other divalent metal ions have shown that zinc and manganese are preferred over magnesium, while copper and nickel are not accepted by the enzyme at all. (wikipedia.org)