It is also called alanine aminotransferase ( ALAT ) and was formerly called serum glutamate-pyruvate transaminase (SGPT) or serum glutamic-pyruvic transaminase (SGPT) and was first characterized in the mid-1950s by Arthur Karmen and colleagues. (wikidoc.org)
In 2000, the American Association for Clinical Chemistry determined that the appropriate terminology for AST and ALT are aspartate aminotransferase and alanine aminotransferase. (wikidoc.org)
In this genetic association study of 3557 children, adolescents, and young adults receiving ALL therapy, variants in UGT1A1 and PNPLA3 were associated with hyperbilirubinemia and elevated alanine aminotransferase and aspartate aminotransferase levels, respectively. (cdc.gov)
Protein9
protein_coding" "AAC73733","dacA","Escherichia coli","D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) [Ensembl]. (ntu.edu.sg)
Penicillin-binding protein 5, D-alanyl-D-alanine carboxypeptidase [Interproscan]. (ntu.edu.sg)
Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins ( PUBMED:8244965 ). (embl-heidelberg.de)
Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein ( PUBMED:10669609 ). (embl-heidelberg.de)
Rod binding protein, Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [Interproscan]. (ntu.edu.sg)
A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1. (colorado.edu)
Interferons are a family of naturally occurring, small protein molecules with molecular weights of 15,000 to 21,000 daltons that are produced and secreted by cells in response to viral infections or to various synthetic and biological inducers. (nih.gov)
It also arises together with lactate and generates glucose from protein degradation via the alanine cycle. (ymdb.ca)
B-raf belongs to the the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which may be constitutively activated due to BRAF gene mutations. (blogspot.com)
Subunit1
Has-miR3944-3p is a putative target of BAG1 (BCL2 associated athanogene 1(log 2 (foldchange) = 1.31978) and has-miR3944-5p of ITGAV (integrin subunit alpha V(log 2 (foldchange) = 1.46107) and RHOD (ras homolog family member D(log 2 (foldchange) = 1.28851). (biomedcentral.com)
Adenylosuccinate synthetase5
Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. (embl-heidelberg.de)
Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. (embl-heidelberg.de)
The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. (embl-heidelberg.de)
Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana. (embl-heidelberg.de)
Catalyzing the first step in the de novo synthesis of adenylmonophosphate, adenylosuccinate synthetase (AdSS) is a known target for herbicides and antibiotics. (embl-heidelberg.de)
Proteins1
Periplasmic binding proteins and sugar binding domain of LacI family [Interproscan]. (ntu.edu.sg)
Glycine1
Alanine and derivatives are compounds containing alanine or a derivative thereof resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. (ymdb.ca)
Ligase1
The systematic name of this enzyme class is gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming). (wikipedia.org)
ALT catalyzes the transfer of an amino group from L-alanine to α-ketoglutarate , the products of this reversible transamination reaction being pyruvate and L-glutamate . (wikidoc.org)
Compounds1
belongs to the class of organic compounds known as alanine and derivatives. (ymdb.ca)
TRNA2
Leucyl-tRNA synthetase, tRNA synthetases class I (I, Anticodon-binding domain of tRNA [Interproscan]. (ntu.edu.sg)
Recent research provides evidence that non-proteinogenic amino acid BMAA produced by cyanobacteria have multiple effects on translation process and bypasses the proof-reading ability of the aminoacyl-tRNA-synthetase. (bvsalud.org)
Synthase3
In enzymology, a homoglutathione synthase (EC 6.3.2.23) is an enzyme that catalyzes the chemical reaction ATP + γ-L-glutamyl-L-cysteine + β-alanine ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate + γ-Lglutamyl-L-cysteinyl-β-alanine The 3 substrates of this enzyme are ATP, gamma-L-glutamyl-L-cysteine, and beta-alanine, whereas its 3 products are ADP, phosphate, and gamma-L-glutamyl-L-cysteinyl-beta-alanine. (wikipedia.org)
Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of the amino acid positions. (nih.gov)
Alanine (abbreviated as Ala or A) is an alpha-amino acid. (ymdb.ca)
Alanine: It is used in a wide variety of cosmetics and personal care products as a skin conditioning agent, anti-static agent and masking ingredient, and as an amino acid, may combine with the epidermal cells to fill up creases, and thus provide the surface of your skin with a smoother appearance. (nakedactives.com)
Belongs1
Beta Glucan (Yeast): Beta-glucan belongs to a class called biological response modifiers. (nakedactives.com)
In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. (embl-heidelberg.de)
1996). P450s are named with the prefix CYP or P450 followed by an Arabic number defining the family, an uppercase letter defining the subfamily, and another Arabic number defining an individual enzyme (e.g. (studyres.com)
Alanine transaminase ( ALT ) is a transaminase enzyme ( EC 2.6.1.2 ). (wikidoc.org)
Metabolic1
Alanine is tightly coupled to metabolic pathways such as glycolysis, gluconeogenesis, and the citric acid cycle. (ymdb.ca)
Interproscan4
Ftsk gamma domain, FtsK alpha domain, FtsK/SpoIIIE family, 4TM region of DNA translocase FtsK/SpoIIIE [Interproscan]. (ntu.edu.sg)
AAA C-terminal domain, MgsA AAA+ ATPase C terminal, ATPase family associated with various cellular activities (AAA) [Interproscan]. (ntu.edu.sg)
CoA-transferase family III [Interproscan]. (ntu.edu.sg)
Class1
Cacaoidin is produced by the strain Streptomyces cacaoi CA-170360 and represents the first member of the new lanthidin (class V lanthipeptides) RiPP family. (mdpi.com)
Alpha1
Type-I interferons include a family of more than 25 alpha interferons as well as beta interferon and omega interferon. (nih.gov)
Gene1
Examples of interferon-stimulated gene products include 2'5' oligoadenylate synthetase (2'5'OAS) and β-2 microglobulin. (nih.gov)
Transcription1
1) permit the largest download of programs and are the best described family from a archival and such transcription of tradition. (erik-mill.de)
This disorder shuttles activated as Family B( associate anticodon, result 2) congenital roles. (erik-mill.de)
Receptor1
The CD40 receptor, a member of the tumor necrosis factor (TNF) receptor super-family, is highly expressed on most B-lineage hematologic malignancies including multiple myeloma, non-Hodgkin lymphoma, chronic lymphocytic leukemia, Hodgkin disease and acute lymphoblastic leukemia. (blogspot.com)
Specific2
Other names in common use include homoglutathione synthetase, and beta-alanine specific hGSH synthetase. (wikipedia.org)
An specific precursor family is converted when the mechanism of the Celsius complex T is BBS-associated that it cannot be implicated by the AP cell complex of POLB. (erik-mill.de)
Enzymes1
In order to systematically identify and categorize this growing family of enzymes, a leading group of researchers in the field established the current system of nomenclature (Nelson et al. (studyres.com)
Member1
A family of bacteriophages containing one genus (Cystovirus) with one member (BACTERIOPHAGE PHI 6). (lookformedical.com)
COMPLEX1
Chronic exposure to the Cyanobacteria biotoxin Beta-methylamino-L-alanine (BMAA) has been associated with development of a sporadic form of ALS called Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC), as observed within certain Indigenous populations of Guam and Japan. (bvsalud.org)