• mice
  • In contrast, DGAT2−/− mice have reduced triglyceride levels but are lipopenic, suffer from skin barrier abnormalities (including the inability to retain moisture), and die shortly after birth. (wikipedia.org)
  • The fact that DGAT1 is unable to compensate for the deficiency in DGAT2 knockout mice indicates that each DGAT isoform has unique functions in TAG biosynthesis during mammal development. (biomedcentral.com)