• biological
  • The use of a common cutting instrument for excising a standard-sized piece of paper that contains the material also introduces the potential for transferring biological material from one sample to subsequent samples, causing false-positive results by PCR. (edu.au)
  • laboratory
  • The Jaffe reaction, despite its nonspecificity for creatinine, is still widely employed as the method of choice for creatinine testing due to its speed, adaptability in automated analysis, and cost-effectiveness, and is the oldest methodology continued to be used in the medical laboratory. (wikipedia.org)
  • blood
  • In the relevant reaction, hydrogen peroxide reacts with the hemoglobin in the blood. (wikipedia.org)
  • In 1903, Erich Meyer in Germany found that blood cells could also trigger the reaction. (wikipedia.org)
  • It was Otto Folin (1867-1934), a Harvard biochemist, who adapted Jaffe's research-abandoning the standard Neubauer reaction of the time-and published several papers using the Jaffe reaction to analyze creatinine levels in both blood and urine. (wikipedia.org)
  • samples
  • Improperly prepared tissue samples may give false positives In research, this reaction is used to stain cells that were prepared with hydrogen peroxidase enzyme, following common immunocytochemistry protocols. (wikipedia.org)
  • specific
  • Paper strips are often specific to a single reaction (e.g. pH measurement), while the strips with pads allow several determinations simultaneously. (wikipedia.org)
  • color change
  • A 3-10% solution of potassium hydroxide (KOH) gives a color change in some species of mushrooms: In Agaricus, some species such as A. xanthodermus turn yellow with KOH, many have no reaction, and A. subrutilescens turns green. (wikipedia.org)
  • effect
  • The two electrons are supplied by phenolphthalin: HOOH + 2 e− + 2 H+ → 2 H2O The consumption of protons during the course of the reaction has the effect of raising the pH of the solution, but the amount of base produced is negligible compared to the amount of base already present in the reagent mixture. (wikipedia.org)
  • solution
  • In 1886, Max Jaffe (1841-1911) wrote about its basic principles in the paper Über den Niederschlag, welchen Pikrinsäure in normalem Harn erzeugt und über eine neue Reaction des Kreatinins in which he described the properties of creatinine and picric acid in an alkaline solution. (wikipedia.org)