Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. (wikipedia.org)
This bacterium is a facultative anaerobic organism that is catalase-positive and capable of beta-hemolysis. (wikipedia.org)
citation needed] Shortly after, it was sampled from abscesses in a sheep by Hugo von Preisz [hu], and the bacterium was named the "Preisz-Nocard" bacillus until further work by German microbiologists in the mid-1900s, when it was recategorized into the Corynebacterium genus. (wikipedia.org)
C. pseudotuberculosis is a Gram-positive bacterium that can be either coccoid or filamentous rods, which can be organized into palisades. (wikipedia.org)
This bacterium is grown at 37 °C under aerobic or anaerobic conditions, thus C. pseudotuberculosis is a facultative anaerobe. (wikipedia.org)
Comparative analyses of the exoproteomes of two C. pseudotuberculosis strains, in addition to comparison with other experimentally determined corynebacterial exoproteomes, were helpful to gain novel insights into the contribution of the exported proteins in the virulence of this bacterium. (biomedcentral.com)
The present study examined the possibilities that: (i) careful examination of Gram-stained sputum and culture plates may reveal a predominant bacterium such as Corynebacterium spp. (biomedcentral.com)
Internal lymph nodes2
Typical manifestations of CLA in small ruminants include formation of abscesses in superficial and internal lymph nodes, and in visceral organs [ 3 ]. (biomedcentral.com)
Caseous lymphadenitis (CL) is a chronic, contagious bacterial disease that manifests clinically as abscesses of peripheral and/or internal lymph nodes and organs. (msdvetmanual.com)
Caseous lymphadenitis2
In small ruminants, C. pseudotuberculosis causes a disease called caseous lymphadenitis characterized by pyogranulomatous abscess formation. (wikipedia.org)
citation needed] Distribution of C. pseudotuberculosis is mostly traced by examining prevalence of caseous lymphadenitis, the bacterium's main pathological disease. (wikipedia.org)
The first isolation of C. pseudotuberculosis came from a cow lymph node in 1888, by French bacteriologist Edmond Nocard. (wikipedia.org)
Whereas the peripheral form presents as abscesses of single or multiple peripheral palpable lymph nodes, internal CL typically manifests as chronic weight loss and ill thrift. (msdvetmanual.com)
The disease is characterized by abscess formation in or near major peripheral lymph nodes (external form) or within internal organs and lymph nodes (internal form). (msdvetmanual.com)
Prevalence2
citation needed] Although few recent studies have been conducted into its prevalence, data from slaughterhouses in Australia in the late 1980s suggested that C. pseudotuberculosis was affecting 50-60% of sheep. (wikipedia.org)
Although prevalence of CL varies by region and country, it is found worldwide and is of major concern for small ruminant producers in North America. (msdvetmanual.com)
Superficial1
citation needed] Major bacterial spread occurs when superficial abscesses are broken open and release discharge that is then contacted by other animals during grooming, or contaminates feed, water, and bedding that other animals consume. (wikipedia.org)
Virulence1
In fact, one might expect that the majority of the virulence determinants of C. pseudotuberculosis would be present in the exoproteome, i.e . the entire set of bacterial proteins found in the extracellular milieu [ 7 ]. (biomedcentral.com)
Pathogens1
Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that belongs to the so-called CMN ( Corynebacterium-Mycobacterium-Nocardia ) group, a distinct subgroup of the Actinobacteria that also includes other highly important bacterial pathogens, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis . (biomedcentral.com)
Strains2
44 proteins were commonly identified in two different strains, isolated from distinct hosts, then composing a core C. pseudotuberculosis exoproteome. (biomedcentral.com)
Also, multidrug resistance to ≥ 3 classes of antimicrobials was found in 23.5% (8/34) strains. (bvsalud.org)
citation needed] It was finally renamed Corynebacterium pseudotuberculosis in 1948, to reflect that the clinical disease signs were similar to disease caused by M. tuberculosis species. (wikipedia.org)
Infection1
A disease known as ulcerative lymphagenitis can also result from infection with C. pseudotuberculosis in the distal limbs of horses. (wikipedia.org)
Disease2
citation needed] C. pseudotuberculosis also causes disease in horses, and should be considered prevalent in areas where cases of "pigeon fever" and "ulcerative lymphadenitis" have been recorded. (wikipedia.org)
This disease is spread between infected animals by vectors and through contamination of the environment with exudate from abscesses. (wikipedia.org)
This bacterium is grown at 37 °C under aerobic or anaerobic conditions, thus C. pseudotuberculosis is a facultative anaerobe. (wikipedia.org)
Exudate1
This disease is spread between infected animals by vectors and through contamination of the environment with exudate from abscesses. (wikipedia.org)
Anaerobic1
This bacterium is a facultative anaerobic organism that is catalase-positive and capable of beta-hemolysis. (wikipedia.org)
Lymphadenitis3
In small ruminants, C. pseudotuberculosis causes a disease called caseous lymphadenitis characterized by pyogranulomatous abscess formation. (wikipedia.org)
citation needed] Distribution of C. pseudotuberculosis is mostly traced by examining prevalence of caseous lymphadenitis, the bacterium's main pathological disease. (wikipedia.org)
citation needed] C. pseudotuberculosis also causes disease in horses, and should be considered prevalent in areas where cases of "pigeon fever" and "ulcerative lymphadenitis" have been recorded. (wikipedia.org)
Horses3
Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. (wikipedia.org)
A disease known as ulcerative lymphagenitis can also result from infection with C. pseudotuberculosis in the distal limbs of horses. (wikipedia.org)
As vector patterns change with warming temperatures, C. pseudotuberculosis in horses is re-emerging in the United States. (wikipedia.org)
Australia1
citation needed] Although few recent studies have been conducted into its prevalence, data from slaughterhouses in Australia in the late 1980s suggested that C. pseudotuberculosis was affecting 50-60% of sheep. (wikipedia.org)