Factors corneal opacity. Medical search. Frequent questions

Paradoxically, in developing whereby the malposition of eyelashes leads to abrasion of countries the use of cataract surgical services among the cornea and, in some cases, corneal ulceration and scar- women is considerably lower than among men (4). (cdc.gov)
This nationally representative population-based survey indicates that more than 1 in 10 Bangleashi adults aged ≥40 years have low vision or blindness, with cataract being the single most attributing factor. (bmj.com)
Risk factors for posterior capsule rupture in cataract surgery as reflected in the European Registry of Quality Outcomes for Cataract and Refractive Surgery. (uk.com)
Media opacities included patients with cataract, corneal, or vitreous opacities. (entokey.com)
5. Some patients with myopia have poor epidermal healing, corneal penetration, iatrogenic corneal astigmatism, secondary keratoconus, corneal opacity, fold or displacement of corneal flap, intraoperative corneal perforation with cataract and bacterial eye Enditis. (eugeniaeyewear.com)
blindness in all ages in Sudan was found to be 1.78%, the major causes being cataract, corneal opacities, uncorrected refractive errors, trachoma and onchocerciasis [3]. (who.int)
The leading causes of chronic blindness include cataract, glaucoma, age-related macular degeneration, corneal opacities, diabetic retinopathy, trachoma, and eye conditions in children (e.g. caused by vitamin A deficiency). (who.int)
A cataract is a congenital or degenerative opacity of the lens. (msdmanuals.com)
Congenital Cataract Congenital cataract is a lens opacity that is present at birth or shortly after birth. (msdmanuals.com)
A posterior subcapsular cataract disproportionately affects vision because the opacity is located at the crossing point of incoming light rays. (msdmanuals.com)

In rare instances, this opacity is congenital. (wikipedia.org)
The purpose of this study is to examine the therapeutic efficacy of human umbilical cord mesenchymal stem/stromal cells (UMSCs) in treating congenital and acquired corneal opacity associated with the loss of collagen V. (molvis.org)
Congenital corneal opacities. (cvs.com)
Available at: https://www.aao.org/topic-detail/congenital-corneal-opacities-europe. (cvs.com)
It is either congenital or acquired (due to ageing, diabetes, injury) and corresponds to opacity of the lens, gradually leading to diminished vision. (who.int)

Experimental mice, i.e., wild-type, Col5a1 f/f and Kera-Cre/Col5a1 f/f ( Col5a1 ∆st/∆st , collagen V null in the corneal stroma) mice in a C57BL/6J genetic background, were subjected to a lamellar keratectomy, and treated with or without UMSC (10 4 cells/cornea) transplantation via an intrastromal injection or a fibrin plug. (molvis.org)
UMSC transplantation was successful in recovering some corneal transparency in injured corneas of wild-type, Col5a1 f/f and Col5a1 ∆st/∆st mice. (molvis.org)
The conservative treatment modalities, such as spectacles and gas permeable rigid contact lenses, become insufficient for visual rehabilitation in the advanced stages of KC, and 10-20% of patients need corneal transplantation [ 3 ]. (hindawi.com)
Corneal transplantation is one of the common treatment to correct several corneal opacity which involves tissue from human donor. (medgadget.com)
However, the treatment fails in some cases, leading to development of keratoprosthesis which is used when corneal transplantation is not an option. (medgadget.com)
Increasing incidences of corneal blindness along with patients who have failed human corneal transplantation may create potential growth prospects of the keratoprosthesis market. (medgadget.com)
No effective therapies for corneal fibrosis have been developed and the most reliable treatment option is corneal transplantation, which has numerous limitations/ and complications, including post-surgical corneal fibrosis. (hhs.gov)
Following full-thickness corneal transplantation (Penatrating Keratoplasty, PK), rejection may involve any cellular layer of the cornea (epithelium, stroma or endothelium). (college-optometrists.org)

Whichever, it is always potentially serious and sometimes necessitates urgent treatment and corneal opacities are the fourth leading cause of blindness. (wikipedia.org)
To avoid blindness and restore the damaged eye corneal surgery is the most adopted choice. (medgadget.com)
Around 10 million people in the world suffering from corneal blindness. (medgadget.com)
Therefore, rising incidences of corneal blindness are the primary factor driving the growth of the global keratoprosthesis market. (medgadget.com)
Up to one fourth of all cases of blindness worldwide are attributable to corneal opacities generated by scarring, or fibrosis, representing a huge economic and societal burden. (hhs.gov)
Trachomatous trichiasis is the potential stage of trachoma in which the eyelashes scratch the surface of the globe, ultimately causing corneal opacity, visual impairment and blindness. (archive.org)
Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. (lookformedical.com)
There are displaced camps in Khartoum indicate that marked differences in the causes of child- the crude mortality rate for children under hood blindness in different regions due to 5 years is near the emergency threshold of different socioeconomic factors. (who.int)
Clearly living conditions are cause of blindness in children in developing poor in the camps and child mortality is countries is corneal opacification caused by high, which suggests visual impairment a combination of measles, xerophthalmia may also be high among such children. (who.int)

Corneal epithelial disruptions may be detected with fluorescein staining of the eye, and careful observation with cobalt-blue light. (wikipedia.org)
Corneal epithelial disruptions would stain green, which represents some injury of the corneal epithelium. (wikipedia.org)
Though some case series report limited success of stabilizing biomechanics of corneas with RK [4] , such tailored control of wound healing and which areas preferentially tighten may be challenging as certain wounds could gape in comparison to non-incised corneal areas based on the amount of epithelial plugging. (aao.org)
These include LV owing to corneal diseases, such as keratokonus, corneal dystrophies, opacities caused by infections, or corneal epithelial stem cell deficiency. (fortunejournals.com)
Corneal epithelial-stromal and stromal dystrophies are a group of inherited disorders of the cornea that are caused by progressive accumulation of deposits within the layers of the cornea. (uiowa.edu)
The 2015 International Committee for Classification of Corneal Dystrophies (IC3D) classification system has divided corneal dystrophies into 4 categories: epithelial and subepithelial dystrophies, epithelial-stromal dystrophies, stromal dystrophies, and endothelial dystrophies. (uiowa.edu)
Epithelial-stromal dystrophies are caused by mutations in transforming growth factor beta-induced (TGFβI) gene, also known as the BIGH3 gene. (uiowa.edu)
Lattice corneal dystrophy (LCD) is the most common of the corneal epithelial-stromal dystrophies. (uiowa.edu)
Other corneal dystrophies ( granular I or Groenouw type I , combined granular/lattice or Avellino type , Thiel-Behnke , Reis-Bucklers , epithelial basement membrane disease ) have mutations in the same region of the same gene casting doubt on the value of using solely clinical and histologic distinctions in current classifications of these corneal disorders. (arizona.edu)
This is another autosomal dominant corneal dystrophy resulting from mutations in the TGFBI gene (5q31) (others being Reis-Bucklers , Thiel-Behnke , lattice types I and IIIA, epithelial basement membrane disease , and Avellino ). (arizona.edu)
Once improved, go to step 2 Place small a viral cause should not be treated with the corneal epithelium may cause superficial punctate keratopathy, followed by focal areas of epithelial opacities. (totoscleaning.com)

They were placed into 1 of 4 categories based on the cause of the visual impairment: 1) optic neuropathy, 2) macular disease, 3) media opacity, or 4) amblyopia. (entokey.com)
We investigated the effectiveness of wearable laser-eyewear (LEW) in visual impairment owing to corneal disease, including low vision (LV) eye. (fortunejournals.com)

The disease is found mainly trichiasis, active trachoma and trachoma in remote rural areas of most African counp risk factors. (who.int)
The aim of this systematic review and meta-analysis is to obtain the pooled prevalence and associated factors of postoperative trachomatous trichiasis (PTT) in World Health Organization (WHO) trachoma-endemic regions. (archive.org)

A reduction in visual acuity in a 'red eye' is indicative of serious ocular disease, such as keratitis, iridocyclitis, and glaucoma, and never occurs in simple conjunctivitis without accompanying corneal involvement. (wikipedia.org)
Ciliary flush is usually present in eyes with corneal inflammation, iridocyclitis or acute glaucoma, though not simple conjunctivitis. (wikipedia.org)
Those with conjunctivitis may report mild irritation or scratchiness, but never extreme pain, which is an indicator of more serious disease such as keratitis, corneal ulceration, iridocyclitis, or acute glaucoma. (wikipedia.org)
To test whether adult mice can regain this ability, the researchers crushed the optic nerves of some mice and induced glaucoma in another set of mice by inserting tiny beads into their eyes, then injected the virus encoding the three transcription factors into all the mice's eyes. (the-scientist.com)

Corneal opacities and diabetic retinopathy were associated with the highest ORs of 3.21and 2.74 respectively. (uk.com)

Seven such signs are: Reduced visual acuity Ciliary flush (circumcorneal injection) Corneal abnormalities including edema or opacities ("corneal haze") Corneal staining Pupil abormalities including abormal pupil size Abnormal intraocular pressure Severe pain The most useful is a smaller pupil in the red eye than the non-red eye (opposite eye) and sensitivity to bright light. (wikipedia.org)
In January 1992, FDA approved Boston KPro for patients suffering with severe corneal opacity. (medgadget.com)
Objective ·To explore the epidemiological characteristics of severe asthma in children and analyze the risk factors. (shsmu.edu.cn)
Our cases suggest the efficacy of Infliximab (case 1) and Rituximab (case 2) as a treatment of this severe and destructive keratolysis of the cornea complicating an active RA allowing to plan corneal graft. (biomedcentral.com)
We have observed that the commonly used ketamine/xylazine anesthesia mix can induce a focally severe and permanent corneal opacity. (annexpublishers.co)
Severe visual dysfunction is observed as ocular sequelae in individuals with Hansen's disease in addition to factors related to aging. (or.jp)

It is typically an autosomal dominant, bilateral disease that typically presents toward the end of the first decade of life with symptoms of recurrent corneal erosions and decreased vision. (uiowa.edu)
Recurrent corneal erosions benefit from standard treatments while penetrating keratoplasty may be necessary by the fifth decade to improve acuity. (arizona.edu)
The number and morphology of the granular deposits change throughout life, influenced to some extent by episodes of recurrent corneal erosions and age of patients. (arizona.edu)

The old classification for corneal stromal dystrophies is listed in Table 3. (uiowa.edu)
Lattice corneal dystrophy type I is one of the more common corneal dystrophies and occurs throughout the world. (arizona.edu)

To investigate the potential predictive factors of the visual change achieved with accelerated epi-on and epi-off corneal collagen crosslinking (CXL) in keratoconus. (hindawi.com)
2 ] demonstrated that the lower pretreatment corneal asphericity and corneal keratoconus index (CKI) were associated to a higher K max reduction after CXL [ 2 ]. (hindawi.com)
Purpose To investigate recipient and operative factors that can influence the rate of achieving a bare Descemet's membrane (DM) during deep anterior lamellar keratoplasty (DALK) for keratoconus. (bmj.com)

If successful, the results from the proposed studies could have far-reaching scientific and clinical significance, as the understanding of corneal fibrotic mechanisms and the role of S1P as an important mediator would not only be important for clinical management/treatment of corneal fibrosis, but could also be applicable to many diseases in which fibrosis is a major pathological outcome, such as liver, lung, and cardiac fibrosis. (hhs.gov)

Reis-Bücklers, formerly known as Granular corneal dystrophy type III or Corneal Dystrophy of Bowman's type I, typically present with normal corneas at birth but develop painful recurrent erosions, opacification, and progressive vision loss within the first decade of life (1). (uiowa.edu)
Patients with corneal opacification may require ophthalmoscopic examination and corneal or intraocular imaging. (medscape.com)

Maintenance of a transparent corneal stroma is imperative for proper vision. (molvis.org)
The corneal stroma is composed of primarily collagen fibrils, small leucine-rich proteoglycans (SLRPs), as well as sparsely distributed cells called keratocytes. (molvis.org)
Being a small protein roughly the size of albumin, it has the capability to diffuse through the corneal stroma. (uiowa.edu)
Irregular, grey-white, geographic-like opacities are located in the Bowman layer and anterior stroma. (uiowa.edu)
In more advanced stages of the disease, the opacities can extend to the limbus and deeper stroma (2). (uiowa.edu)
It is characterized by lattice lines which are linear, radially oriented, branching refractile opacities described as 'glass like' located in the anterior stroma (See Figure 2A and 2B). (uiowa.edu)
Randomly oriented linear opacities resembling cotton threads accumulate in the central portions of the stroma. (arizona.edu)
The corneal opacities in this disorder are usually located in the anterior stroma of the central cornea, and consist of discrete grayish-white, irregular granules with sharp margins. (arizona.edu)
The histologic appearance of the corneal deposits are said to be characteristic with eosinophilic deposits in the anterior stroma secondary to accumulations of mutant transforming growth factor beta induced protein. (arizona.edu)

In the epi-off group, the CDVA change could be predicted from the preoperative minimum corneal thickness and magnitude of the vertical anterior corneal primary coma component ( = 0.001, R 2 = 0.446). (hindawi.com)
The most significant factor that determined VA improvement in eyes with LV using LEW was the corneal opacity grade, while the corneal topographic parameters, including keratometric refractive parameters (K max , K s , K f , and Cylinder), higher-order aberrations (HOAs), and central corneal thickness (CCT), showed no or limited impact on the VA improvement effect by LEW in LV. (fortunejournals.com)
In patients without a past history of ocular surgery, the mean central corneal thickness was 643.05 ± 37.67 µm and the mean endothelial cell count was 3,349.44 ± 408.17 cells/mm 2 . (ekjo.org)

LEW was performed in 35 patients (38 eyes) with irregular corneal astigmatism. (fortunejournals.com)

Available at:https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/corneal-conditions. (cvs.com)
Rising geriatric population coupled with increasing incidence of eye diseases worldwide is expected to be the prime factor driving the growth of global keratoprosthesis market. (medgadget.com)
Patients were divided into 4 groups according to the etiology of visual loss: 1) optic neuropathies, 2) macular diseases, 3) media opacities, and 4) amblyopia. (entokey.com)
Patients with optic neuropathy had considerably worse average color vision (6.7/15) compared to patients in the other 3 disease categories: 11.1/15 (macular diseases), 13.2/15 (media opacities), and 13.4/15 (amblyopia). (entokey.com)
In this study, we grouped ocular diseases that affect vision into 4 categories: optic neuropathies, macular diseases, media opacities, and amblyopia. (entokey.com)

Opacities may be keratic, that is, due to the deposition of inflammatory cells, hazy, usually from corneal edema, or they may be localized in the case of corneal ulcer or keratitis. (wikipedia.org)

The clarity of the transplanted corneal graft vanished in 5 eyes with the progression of peripheral neovascularization and subepithelial fibrosis. (ekjo.org)
The peripheral cornea and areas between the opacities remain clear. (arizona.edu)
[ 7 ] SED tarda Toledo type is a form of SED tarda with peripheral corneal opacities and a qualitative abnormality of urinary mucopolysaccharides, mainly chondroitin-6-sulfate. (medscape.com)

Because of injury, infection or inflammation, an area of opacity may develop which can be seen with a penlight or slit lamp. (wikipedia.org)
Corneal opacity is caused by infection, injury, or swelling of the eye. (cvs.com)
The keratoprosthesis market is expected to grow exponentially over the forecast period due to increasing incidence of corneal infection. (medgadget.com)
Corneal fibrosis is characterized by the formation of corneal scars from over-accumulation of disorganized extracellular matrix (ECM) produced by fibroblasts and myofibroblasts after they are activated by injury or infection. (hhs.gov)
4. Corneal infection, operation or postoperative cleaning and disinfection and other factors caused by improper factors. (eugeniaeyewear.com)

The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. (lookformedical.com)
The incidence of graft rejection depends on the presence of risk characteristics, e.g. corneal neovascularization. (college-optometrists.org)

After a month of treatment, the corneal ulcer healed completely and thinned down the scar on the cornea. (biomedicineonline.org)
Ayurvedic treatment was effective in completely healing the corneal ulcer and controlling the active inflammation, thereby improving vision. (biomedicineonline.org)
In this article, we describe the case of two patients with the history of perforated corneal ulcer complicating RA treated successfully by biologic agents. (biomedcentral.com)
After thirteen months, Infliximab was effective on the rheumatic disease and on the corneal involvement as it stopped its gradual perforation in the right eye, and stabilized corneal ulcer in the left eye. (biomedcentral.com)
Meanwhile, our article shows their success in two RA patients with perforated corneal ulcer on the articular and the ocular manifestations. (biomedcentral.com)

The hyaline-like material consists of rod-like bodies ultrastructurally, which helps distinguish it from Thiel-Behnke corneal dystrophy (1, 2). (uiowa.edu)

TGFβI is located on chromosome 5q31 and codes for keratoepithelin, a protein secreted by corneal epithelium. (uiowa.edu)

Well-developed cataracts appear as gray, white, or yellow-brown opacities in the lens. (msdmanuals.com)

In vivo Heidelberg retinal tomograph (HRT II) confocal microscopy, second harmonic generated (SHG) confocal microscopy, histology, and immunofluorescence microscopy were used to assess the corneal transparency of the regenerated corneas. (molvis.org)
The production of collagen V by transplanted UMSCs may account for the regeneration of corneal transparency, as exemplified by better collagen fiber organization, as revealed with SHG signals. (molvis.org)
Cornea can loss its transparency due to various reasons and it majorly occurs due to some disorders of eye that eventually leads to corneal opacity. (krishnaeyecentre.com)
The lack of knowledge regarding this process is a critical barrier to developing new treatment strategies to minimize scarring and retain or restore corneal transparency. (hhs.gov)

Radial Keratotomy Though the concept of radial keratotomy for altering corneal biomechanics and refractive state has approached near a century since Sato's [2] publication of the described procedure (on the posterior cornea), it wasn't until the latter 20th century when the popularity of the procedure took off being performed on the order of millions worldwide extending into the 1990s as well. (aao.org)

We have also demonstrated that SPL metabolism is altered in "injured" corneal stromal cells, and that stimulation of healthy corneal stromal cells with Sphingosine 1-Phosphate (S1P), a bioactive SPL, induces TGF-ß1 expression and fibrosis, signaling through the S1P receptor 3 (S1P3). (hhs.gov)

Researchers repaired what is otherwise irreversible damage in the animals' ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells. (the-scientist.com)
Few patients are do not undergo surgery owing to ocular risk factors or rejection of surgery [3,4]. (fortunejournals.com)
While contact lens wear is the primary risk factor of the UK in the young, compromised ocular immunity is responsible for it in the old age group. (biomedicineonline.org)
Ocular examination revealed a corneal perforation in the left eye and a pre-perforation in the right eye. (biomedcentral.com)

Standard topography can overestimate central corneal power which results in a post-operative hyperopic surprise. (aao.org)

Postoperative worsening of corneal clouding and glaucomatous damage were observed in 4 eyes. (ekjo.org)

Opacities may also occur following the application of various types of refractive surgery (even in initially clear corneas). (arizona.edu)
The conversation shifts to explaining that factors such as age, refractive error, presbyopia onset, and early lens changes make lens-based refractive surgery a better option. (crstoday.com)

A 68-year-old man had been diagnosed since 2010 with sero-positive RA refractory to csDMARDs complicated in July 2017 by corneal perforation in the right eye. (biomedcentral.com)

The extent of corneal involvement was classified into four grades ( Table 1 ). (ekjo.org)

corneal opacity grade was observed using slit lamp examination. (fortunejournals.com)
Risk factors Eye herpes is highly contagious and the throat or nose by using a cotton general unless ordered by their medical provider The of the speculum, the pelvic examination will cause. (totoscleaning.com)

In a 2016 Cell paper, a different group of scientists had activated these transcription factors in mice with progeria, a condition that causes premature aging, and found that the treatment alleviated symptoms and extended their lifespan by a matter of weeks. (the-scientist.com)
After six months, we observed the stabilization of the right eye corneal damage and the resolution of articular symptoms. (biomedcentral.com)
Usual y, the beginning occurs in an insidious way and without symptoms and, in many cases, can explain the delay in its diagnosis(1), considered a risk factor for the development of disabilities. (bvsalud.org)

To review the evidence on screening for and treatment of amblyopia, its risk factors, and refractive error in children aged 6 months to 5 years to inform the US Preventive Services Task Force. (uspreventiveservicestaskforce.org)
Positive likelihood ratios were between 5 and 10 for amblyopia risk factors or nonamblyogenic refractive error in most studies of test accuracy and were greater than 10 in most studies evaluating combinations of clinical tests. (uspreventiveservicestaskforce.org)
The most common causes of vision problems in children are amblyopia (a neurodevelopmental disorder that arises from abnormal processing of visual images that leads to a functional reduction of visual acuity) and its associated risk factors ( Table 1 ), nonamblyopic strabismus and nonamblyopic refractive error. (uspreventiveservicestaskforce.org)
Amblyopia was diagnosed by a patient's self-report of a unilateral "lazy eye" since early childhood, and only when an amblyogenic factor was established by the examiner (Y.A. (entokey.com)

For this reason, CXL research in recent years has attempted to define the predictive factors for the outcomes achieved with this technique with the aim of helping the clinicians manage the patients' expectations and minimize the exposure to potential side effects. (hindawi.com)
The keratoprosthesis is intended to replace the damaged corneal tissue and restore vision of the patients with bilateral corneal disease. (medgadget.com)
foveal hypoplasia is a major factor that can decrease visual function in these patients [ 5 ]. (ekjo.org)
As the opacities enlarge and grow in number the cornea becomes increasingly opaque and older patients experience considerable loss of vision. (arizona.edu)

Corneal opacity is a disorder of the cornea that occur due to scarring or clouding of the normally clear and transparent cornea. (krishnaeyecentre.com)

Theoretically, the OCT optical system is known to be affected by a magnification factor related to the eye attributable to axial length and refraction power difference from default values. (bmj.com)

Although there are so many reasons or eye disorders that can lead to corneal opacity but still some risk factors increases the chances of development of corneal opacity. (krishnaeyecentre.com)
cal data were collected from children and The risk factors that predispose to infecp elderly people. (who.int)
Risk factors of post-dural puncture headache receiving a blood-patch in the obstetric patient. (annexpublishers.co)
The objective is to determine risk factors of PDPH receiving a blood-patch in the obstetric population. (annexpublishers.co)
Many cancers can be prevented by avoiding exposure to common risk factors, such as tobacco smoke. (who.int)
Many people have no risk factors other than age. (msdmanuals.com)

There is some variation in the number of opacities among individuals and considerable clinical heterogeneity occurs both within and between families. (arizona.edu)

Corneal opacity ("blue eye") and interstitial nephritis may occur 1-3 weeks after recovery due to deposition of immune complexes in these organs. (petboardinganddaycare.com)
Corneal erosions may occur in the absence of stromal infiltrates. (arizona.edu)

To avoid such out-of-control proliferation, which would risk causing cancerous growth, Sinclair's team eliminated one of the Yamanaka factors from their study- MYC , which is a known oncogene-and fitted the remaining three into an adeno-associated virus and injected it into mice. (the-scientist.com)
and in vivo models of corneal wound healing in wild type, Sphk1, and S1P3 knockout mice, along with testing the therapeutic potential of targeting S1P and TGF-ß signaling using selective inhibitors in these models (Aim 2). (hhs.gov)
Ketamine/Xylazine-Induced Corneal Damage in Mice. (annexpublishers.co)

Could transmission of C. trachomatis to the eye by hands, flies, other factors help explain the excess of conjunctival scarring or cloth. (cdc.gov)

Central corneal power is not the real corneal power required for IOL calculations. (aao.org)

The forkhead box D3 ( FOXD3 ) gene encodes a forkhead transcription factor that plays an important role in neural crest specification in vertebrates and therefore may be involved in human eye disease. (molvis.org)
The atonal homolog 7 (ATOH7) gene encodes a transcription factor involved in determining the fate of retinal progenitor cells and is particularly required for optic nerve and ganglion cell development. (aber.ac.uk)

Based on these discoveries, we hypothesize that S1P is a key mediator of corneal fibrosis via activation of TGF-ß, and TGF-ß in turn induces expression of S1P signaling proteins and thus forms a positive feedback loop which drives irreversible activation of corneal fibroblasts and differentiation to myofibroblasts. (hhs.gov)

Anatomy12

Diseases24

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Psychiatry and Psychology2

Phenomena and Processes1

Disciplines and Occupations1

Humanities1

Cataract10

Congenital5

Transplantation8

Blindness9

Epithelial11

Visual impairment2

Trachoma2

Glaucoma4

Diabetic retinopathy1

Severe6

Recurrent corneal erosions3

Dystrophies2

Keratoconus3

Treatment of Corneal1

Opacification2

Stroma9

Thickness3

Astigmatism1

Diseases5

Keratitis1

Peripheral3

Infection5

Graft2

Ulcer5

Dystrophy1

Epithelium1

Cataracts1

Transparency4

Posterior1

Stromal cells1

Ocular4

Hyperopic1

Postoperative1

Refractive surgery2

Perforation1

Involvement1

Examination2

Symptoms3

Amblyopia4

Patients4

Disorder1

Attributable1

Risk factors6

Clinical1

Occur2

Mice3

Conjunctival1

Central1

Gene2

Irreversible1