• Recent imaging studies using fMRI and PET techniques have demonstrated the regional effects of propofol on the brain. (crohnsforum.com)
  • In contrast, several recent fMRI studies are consistent on the systemic decreased effects of propofol in the frontoparietal network. (crohnsforum.com)
  • One recent technology that is very exciting, but insiders recognize is very problematic, is perhaps even more problematic than we thought -functional MRI scans (fMRI). (sciencebasedmedicine.org)
  • Functional MRI takes it one step further - it images blood flow using a technique known as blood oxygenation level dependent (BOLD) imaging. (sciencebasedmedicine.org)
  • H(2)(15)O]-Positron Emission Tomography (PET) was used to examine regional cerebral blood flow (rCBF) after administration of a single oral dose of the serotonin realeaser and uptake inhibitor MDMA (1.7 mg/kg) or placebo to 16 MDMA-naïve subjects. (researchgate.net)
  • PET imaging revealed decreased regional cerebral blood flow (rCBF) in areas including the left amygdala, dorsal anterior cingulate, posterior cingulate, medial temporal lobe (MTL), and bilateral insula (Gamma et al, 2000). (researchgate.net)
  • In the unconscious state, propofol sharply reduces the regional glucose metabolism rate (rGMR) and regional cerebral blood flow (rCBF) in all brain regions, particularly in the thalamus. (crohnsforum.com)
  • The authors quantified the effects of sevoflurane and propofol as sole anesthetics and in combination with N2O on regional cerebral blood flow (rCBF), metabolic rate of oxygen (rCMRO2), and blood volume (rCBV) in the living human brain using positron emission tomography. (silverchair.com)
  • The purpose of this study was to measure regional cerebral blood flow (rCBF) following acupuncture at LI-10 Shousanli in healthy volunteers using 99m Tc-ethyl cysteine dimer ( 99m Tc-ECD) single-photon emission computed tomography (SPECT). (jmedscindmc.com)
  • In our study, we aim to develop a cerebral blood perfusion (CBF) single-photon emission computed tomography computer-aided (SPECT-CA) detection scheme to automatically locate the brain's activated regions after rehabilitation. (biomedcentral.com)
  • Our study demonstrated that the CBF SPECT-CA method can detect the brain blood perfusion changes induced by rehabilitation with high sensitivity and accuracy. (biomedcentral.com)
  • Brain imaging, such as functional magnetic resonance (fMRI) and CBF SPECT/CT, can provide useful brain functional information. (biomedcentral.com)
  • CBF SPECT/CT imaging is used to measure regional cerebral blood flow changes elicited by stimulation or activation of behavioral functions, which may reflect changes in the underlying neuronal network. (biomedcentral.com)
  • Regional cerebral blood flow of thalamus was assessed bilaterally by iodine-123-labelled iodoamphetamine SPECT. (openneuroimagingjournal.com)
  • Using fMRI, several studies observed a decrease of connectivity of the thalamus versus an increase of connectivity within the pons of the brainstem during propofol-induced mild sedation. (crohnsforum.com)
  • Yeh SH, Lin CH, Chang PY, Lin LF, Tang SE, Chiu CH. Increased cerebral blood flow following L110 acupuncture in healthy volunteers observed with 99m Tc-ethyl cysteine dimer single-photon emission computed tomography. (jmedscindmc.com)
  • A systematic search was conducted of acute THC-challenge studies using fMRI, PET, and arterial spin labelling in accordance with established guidelines. (kcl.ac.uk)
  • We also investigated whether the neuromodulatory effects of THC are related to the local expression of its key molecular target, cannabinoid-type-1 (CB1R) but not type-2 (CB2R) receptor.MethodsA systematic search was conducted of acute THC-challenge studies using fMRI, PET, and arterial spin labelling in accordance with established guidelines. (kcl.ac.uk)
  • Regional effects of magnetization dispersion on quantitative perfusion imaging for pulsed and continuous arterial spin labeling. (mpg.de)
  • Functional localization in the human brain: gradient-echo, spin-echo, and arterial spin-labeling fMRI compared with neuronavigated TMS. (mpg.de)
  • When a part of the brain is active there is an initial dip in blood oxygenation as the neurons consume oxygen, but then blood flow increases bringing more oxygen to the tissue. (sciencebasedmedicine.org)
  • Microcirculation facilitates tissue oxygenation and the exchange of substances between tissues and blood. (springeropen.com)
  • Also, sluggish blood oxygenation level-dependent (BOLD) signal responses to tasks, reduced serotonin transporters, and regional hypometabolism are consistent observations by more than two research teams. (biomedcentral.com)
  • Monitoring microcirculatory flow offers the potential to enhance monitoring in the care of critically ill patients, and imaging retinal blood flow during critical illness offers a potential biomarker for cerebral microcirculatory perfusion. (springeropen.com)
  • The aim of the present study was to explore the effects of selective REM sleep deprivation (REM-D) on emotional responses to threatening visual stimuli and their brain correlates using functional magnetic resonance imaging (fMRI). (frontiersin.org)
  • Scientists are analyzing more than 7,000 studies of functional magnetic resonance imaging (fMRI) to refine the role of various regions of the brain, according to unpublished work presented in a poster Monday at the 2011 Society for Neuroscience annual meeting in Washington, D.C. (spectrumnews.org)
  • In order to obtain the most unbiased estimate of how whole-brain network states evolve through the human sleep cycle, we used a Markovian data-driven analysis of continuous neuroimaging data from 57 healthy participants falling asleep during simultaneous functional magnetic resonance imaging (fMRI) and EEG. (nature.com)
  • Negative functional magnetic resonance imaging (fMRI) response in the striatum has been observed in several studies during peripheral sensory stimulation, but its relationship between local field potential (LFP) remains to be elucidated. (tmu.edu.tw)
  • The frequent observation of additional brain area recruitment and consistent observation of sluggish fMRI signal response suggest abnormal neurovascular coupling in ME/CFS. (biomedcentral.com)
  • Neurovascular dysfunction, including blood-brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, is increasingly recognized as contributing to Alzheimer disease. (medscape.com)
  • The body of literature using fMRI is valuable, but small studies interpreted in isolation are less so, says lead investigator Michael Anderson , assistant professor of cognitive science at Franklin and Marshall College in Pennsylvania. (spectrumnews.org)
  • Anderson and his colleagues analyzed thousands of fMRI studies to ask just this question: Is the brain divided up into different areas that each play a different role in cognition? (spectrumnews.org)
  • Reduced resting cerebral blood flow and volumetric brain changes are inconsistent observations across different studies. (biomedcentral.com)
  • This coordinate-based meta-analysis included voxel-based morphometry (VBM) studies and resting-state voxel-based pathophysiology (VBP) studies of blood flow, glucose metabolism, regional homogeneity, and amplitude of low-frequency fluctuations (ALFF) and fractional ALFF (fALFF). (psychiatryonline.org)
  • The anatomy of language: a review of 100 fMRI studies published in 2009, Cathy J. Price (Ann. (rsna.org)
  • Of particular importance to the present study is the prior result of decreased regional brain blood flow in the insula, a region implicated in visceral and somatosensory sensation, following MDMA administration (Gamma et al, 2000) . (researchgate.net)
  • Already we can see that interpreting the results of an fMRI study involves a chain of inference. (sciencebasedmedicine.org)
  • Ten patients with complex regional pain syndrome (CRPS) and eleven radiculopathiy patients were enrolled in this study. (openneuroimagingjournal.com)
  • The simulation study revealed that our proposed method for measuring CSF flow could be used to generate secondary cases infected by individuals who developed symptoms before day 15 and then slightly rebounded to 2. (soisdetraca.com)
  • Quantifying the Link between Anatomical Connectivity, Gray Matter Volume and Regional Cerebral Blood Flow: An Integrative MRI Study. (mpg.de)
  • We have investigated the neuronal circuitry that underlies reexperiencing/hyperaroused and dissociative responses in PTSD using BOLD fMRI and script-driven imagery. (psychiatrictimes.com)
  • Albeit high LFP-CBV correlation was found in the ipsilateral and contralateral sensory cortices (r = 0.89 and 0.95, respectively), the striatal CBV responses were neither positively, nor negatively correlated with LFP (r = 0.04), demonstrating that the negative striatal CBV response is not originated from net regional inhibition. (tmu.edu.tw)
  • Nonlinear Responses in fMRI: The Balloon Model, Volterra Kernels, and Other Hemodynamics. (rsna.org)
  • We performed cerebral blood volume (CBV) fMRI and LFP recordings in normal rats during graded noxious forepaw stimulation at nine stimulus pulse widths. (tmu.edu.tw)
  • Chronic abuse of MA can cause change in regional cerebral blood flow, glucose metabolism, certain biochemical substances, and even local brain structures. (tws.org.cn)
  • S+N especially reduced the oxygen extraction fraction, suggesting disturbed flow-activity coupling in humans at a moderate depth of anesthesia. (silverchair.com)
  • Parallel mechanisms autoregulate retinal and cerebral microcirculation to maintain blood flow to meet metabolic demands across a range of perfusion pressures. (springeropen.com)
  • This review discusses the relationship between cerebral and retinal blood flow, and the relevance of that relationship to systemic pathology and monitoring microcirculatory perfusion in critical illness, focussing more on sepsis. (springeropen.com)
  • fMRI adaptation between action observation and action execution reveals cortical areas with mirror neuron properties in human BA 44/45. (mpg.de)
  • MDMA also produced increases in blood pressure and several side effects such as jaw clenching, lack of appetite and difficulty concentrating. (researchgate.net)
  • Rat blood flow increases significantly in the temporal cortex, and the medial geniculate body with microwave hearing exposure. (slavery.org.uk)
  • Cerebral blood flow is typically highly correlated with cerebral glucose utilization rates, changing together with local glucose consumption in response to altered local functional activity. (jmedscindmc.com)
  • We then employed a measure of global resting-state functional brain connectivity and follow-up seed-to-voxel analysis to the fMRI data we acquired. (researchgate.net)
  • Software analyses the raw data from fMRI scan to create what are called voxels. (sciencebasedmedicine.org)
  • To dip or not to dip: Reconciling optical imaging and fMRI data. (mpg.de)
  • Quantification of microcirculatory parameters by joint analysis of flow-compensated and non-flow-compensated intravoxel incoherent motion (IVIM) data. (lu.se)
  • In terms of fMRI signal, there was, as expected, an overall decrease in activity in the NREM-I group when subjects performed the task the second time, particularly in regions involved in emotional processing, such as occipital and temporal areas, as well as in the ventrolateral prefrontal cortex, involved in top-down emotion regulation. (frontiersin.org)
  • Decreased cerebral blood flow of the right anterior cingulate cortex in long-term and short-term abstinent methamphetamine users[J]. Drug Alcohol Depend, 2006, 82(2): 177-181. (tws.org.cn)
  • Mood disturbances and regional cerebral metabolic abnormalities in recently abstinent methamphetamine abusers[J]. Arch Gen Psychiatry, 2004, 61(1): 73-84. (tws.org.cn)
  • These reductions in flow and metabolism were partly attenuated by adjunct N2O. (silverchair.com)
  • Journal of Cerebral Blood Flow and Metabolism , 34 (9), 1483-1492. (tmu.edu.tw)
  • A reduction in cerebral blood flow in brain tissue is typically accompanied by a compensatory increase in the oxygen extraction fraction (OEF) to maintain normal neuronal function. (ajnr.org)
  • Single observations include abnormal brain tissue properties, regional metabolic abnormalities, and association of brain measures with ME/CFS symptoms. (biomedcentral.com)
  • Peripheral microcirculatory blood flow may be imaged in sublingual and conjunctival mucosa and is impaired in sepsis. (springeropen.com)
  • One shortcoming of fMRI is that blood flow is an indirect measure and could be the result of a signal that began elsewhere in the brain. (spectrumnews.org)
  • Here, we examined the spatial acute effect of THC on human on regional brain activation or blood flow (hereafter called 'activation signal') in a 'core' network of brain regions that subserve a multitude of processes. (kcl.ac.uk)
  • This stimulus-locked flow signal was not assessed, and Rt (Fig 1, how to get accupril Step 4). (soisdetraca.com)
  • We used functional transcranial Doppler ultrasound (fTCD) to assess cerebral blood flow during language production in 57 four-year-olds, including 15 children who had been late-talkers when first seen at 20 months of age. (peerj.com)
  • To do this, we administered MDMA-HCl (100 mg p.o.) and, separately, placebo (ascorbic acid) in a randomized, double-blind, repeated-measures design with twenty-five healthy volunteers undergoing fMRI scanning. (researchgate.net)
  • 5]Devous M D, Trivedi M H, Rush A J. Regional cerebral blood flow response to oral amphetamine challenge in healthy volunteers[J]. J Nucl Med, 2001, 42(4): 535-542. (tws.org.cn)
  • CT Lung Nodule Volume Measurement for Primary/Regional Nodes and Metastatic Sites uses the UPICT template as a structure. (rsna.org)
  • Regional dGEMRIC analysis in patients at risk of osteoarthritis provides additional information about activity related changes in cartilage structure. (lu.se)
  • Cerebral blood flow (CBF) is reduced and autoregulation impaired in sepsis, but current methods to image CBF do not reproducibly assess the microcirculation. (springeropen.com)
  • Researchers try to correlate such regional activity with specific tasks, and then infer that this part of the brain is involved in that task. (sciencebasedmedicine.org)
  • Then you compare the fMRI activity statistically between the two groups, and can conclude that looking at the specific image correlates with increased activity in one part of the brain, and from that you infer that the active part of the brain is involved in visual processing. (sciencebasedmedicine.org)
  • The results show that, in the Soptimal, hippocampal and posterior cingulate cortex network biomarkers occur first, followed by aberrant cerebrospinal fluid amyloid-β and p-tau levels, then cognitive deficit, and finally regional gray matter loss and fusiform network abnormality. (humanconnectome.org)
  • Neuroscientists have long used fMRI, which detects blood flow in the brain, to determine which brain regions are responsible for certain tasks. (spectrumnews.org)