• sebaceous gland car
  • In this study, we investigated Shh and Wnt signaling protein expression in eyelid sebaceous gland carcinoma, and analyzed their correlation with clinical characteristics of the tumor. (arvojournals.org)
  • Patients who underwent surgical resection of eyelid sebaceous gland carcinoma from 1999 to 2011 were recruited for the study. (arvojournals.org)
  • Thirty-seven cases of eyelid sebaceous gland carcinoma were included in this study. (arvojournals.org)
  • Sebaceous gland carcinoma is one of the most common eyelid malignant neoplasms in Asian. (arvojournals.org)
  • Eyelid sebaceous gland carcinoma is associated with high morbidity and mortality despite complete wide surgical resection because of lymph node metastasis or distant metastasis. (arvojournals.org)
  • Moreover, eyelid sebaceous gland carcinoma tends to be diagnosed in the advanced stage, because this tumor can be easily misdiagnosed as chalazion or chronic conjunctivitis. (arvojournals.org)
  • For effective management of eyelid sebaceous gland carcinoma, which shows poor prognosis, documenting factors associated with treatment outcome or prognosis would be very helpful for the development of an optimal treatment design. (arvojournals.org)
  • Currently, reported conventional prognostic factors for eyelid sebaceous gland carcinoma are larger lesions, incompletely excised tumors, and histopathologic features, such as poor differentiation, multicentric origin, and pagetoid spread. (arvojournals.org)
  • To investigate the expression of cancer stem cell (CSC) marker proteins in eyelid sebaceous gland carcinoma and evaluate the clinical significance. (arvojournals.org)
  • Archival tissue blocks from 50 cases of eyelid sebaceous gland carcinoma were tested via immunohistochemistry for 16 putative CSC markers. (arvojournals.org)
  • Development of metastasis in eyelid sebaceous gland carcinoma might be attributed to increased number of CSCs or acquisition of dedifferentiated phenotype. (arvojournals.org)
  • Our findings suggest that CSCs are involved in the disease progression of eyelid sebaceous gland carcinoma, and in particular, expression of ALDH1 is a predictor of a poor outcome. (arvojournals.org)
  • front
  • For a normal patient, the blink of eye is called as the tonic blink, which is an involuntary action causing the contact between the upper and the lower eyelid to allow lubrication of the front eye. (epainassist.com)
  • Treatment
  • Treatment of dry eye or other ocular conditions may reduce eyelid spasm to a level that the patient can tolerate without the need for additional medications or injections. (calvv.com)