Extracellular edema. Medical search. Frequent questions

Cerebral edema is extracellular fluid accumulation in the brain. (wikipedia.org)
Global cerebral edema occurs after SAH and is associated with BBB disruption. (ajnr.org)
Detection of global cerebral edema using current imaging techniques is challenging. (ajnr.org)
Our purpose was to apply blood-brain barrier permeability imaging in patients with global cerebral edema by using extended CT perfusion. (ajnr.org)
Patients with SAH underwent CTP in the early phase after aneurysmal rupture (days 0-3) and were classified as having global cerebral edema or nonglobal cerebral edema using established noncontrast CT criteria. (ajnr.org)
Extended CTP was used to evaluate blood-brain barrier permeability in patients with SAH with and without global cerebral edema. (ajnr.org)
Further study of blood-brain barrier permeability is needed to improve diagnosis and monitoring of global cerebral edema. (ajnr.org)
Anti-cerebral edema properties of PEG 300 in triethyltin poisoning]. (nih.gov)
Cerebral edema: intra-cellular or extra-cellular mechanisms? (nih.gov)
Role of aquaporin-4 in cerebral edema and stroke. (benthamscience.com)
Mechanisms of astrocyte-mediated cerebral edema. (benthamscience.com)
Igarashi H, Huber VJ, Tsujita M, Nakada T. Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema. (benthamscience.com)
MedicineNet Home MedTerms medical dictionary AZ List cerebral edema. (geometry.net)
cerebral edema AND BRAIN SWELLING A. Vasogenic cerebral edema (most common form ofedema) 1. (geometry.net)
High Altitude cerebral edema HACE. (geometry.net)
48 h), however, should be corrected more slowly due to the risks of cerebral edema during treatment. (medscape.com)
As an obligate extracellular solute it may be useful to ameliorate symptoms of the dialysis disequilibrium syndrome, to decrease cerebral edema following trauma or cerebrovascular accident, and to prevent cell swelling related to renal ischemia following cross-clamping of the aorta. (nih.gov)
Over correction of dehydration is implicated in precipitating cerebral edema. (bmj.com)
A rapid fall in ketone body level can result in a fall in osmolality and osmoticity of the serum and lead to cerebral edema. (bmj.com)
In summary we suggest that changes in ketone body levels be considered, as a factor that can be partially responsible for the cerebral edema often seen during treatment of DKA .We will be glad to share our data at any summit of experts convened to study the enigma of cerebral edema in DKA. (bmj.com)

Pharmacologically it promotes the rapid removal of abnormally retained extracellular fluids. (drugs.com)
In human physiology, extracellular fluids are distributed between the interstitial compartment (i.e. tissue) and intravascular compartment (i.e. plasma) in an approximately 75%-25% ratio. (wikidoc.org)
Sodium, the major cation of the extracellular fluid, functions primarily in the control of water distribution, fluid balance, and osmotic pressure of body fluids. (guidelinecentral.com)
The clinical presentation of Acute Respiratory Distress (ARDS) is marked by disruptions to the alveolar-capillary complex mediated by inflammation, interalveolar edema primarily caused by protein-rich fluids influx, reduced alveolar clearance, and increased pulmonary resistance. (ceufast.com)

During an inflammatory response, neutrophils move from the blood to the site of inflammation by transmigrating across the endothelial barrier and through the basement membrane (BM) of the surrounding extracellular matrix (ECM). (nature.com)
The myocardium consists of cardiomyocytes grouped in strands also known as myofibres and the surrounding extracellular matrix with endomysial and perimysial components. (radiopaedia.org)

Pulmonary edema occurs when the pressure in blood vessels in the lung is raised because of obstruction to the removal of blood via the pulmonary veins. (wikipedia.org)
Pulmonary edema produces shortness of breath. (wikipedia.org)
Described herein are methods and compositions relating to inhibition of mechanically-induced TRPV4 activation, e.g., for the treatment of pulmonary edema, edema, inflammation, hypertension, and/or hyperalgesia. (google.com)
The administration of intravenous solutions can cause fluid and/or solute overload resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. (guidelinecentral.com)

Ultimately, cell membrane ion pump dysfunction occurs, acidosis progresses, intracellular edema develops, intracellular contents leak into the extracellular spaces, and cell death ensues. (medscape.com)
In the setting of an acute fall in the serum osmolality, neuronal cell swelling occurs owing to the water shift from the extracellular space to the intracellular space (ie, Starling forces). (medscape.com)
SECA 515 mBCA differentiates the weight in respect to the most important medical components, such as fat mass, fat free mass, body water (extracellular and intracellular water), and muscle mass. (artbeauty.lv)

In this study, we used the OrganoPlate to develop a humanized 3D in vitro inflammation-on-a-chip model to recapitulate neutrophil transmigration across the endothelium and subsequent migration through the extracellular matrix (ECM). (nature.com)
The inflammation and coagulation response after ICH would accelerate the formation of brain edema around hematoma, resulting in a more severe and durable injury. (karger.com)
There is a short-of-effective medical treatment for secondary inflammation and reducing brain edema in ICH patients. (karger.com)
The inflammation, thrombin activation, and erythrocyte lysis caused by primary injury could promote the formation of brain edema, which is associated with poor outcome, and could cause more severe and durable injury [ 3 ]. (karger.com)
In recent years, many studies focus on the mechanism of secondary inflammation that can cause brain edema and this may provide new therapy targets for ICH [ 7 ]. (karger.com)
CMR identifies areas of increased interstitial space where gadolinium is retained (eg, areas of myocardial infarction, acute edema/inflammation due to capillary leak, myocardial fibrosis/scar, or amyloid protein infiltration). (medscape.com)
T1 and T2 mapping better characterize myocardial tissue by identifying areas of edema (T2), inflammation, and more diffuse fibrosis (T1), which may aid in diagnosing myocarditis without LGE, amyloidosis , hemochromatosis , and Fabry disease . (medscape.com)
AMD, the main cause of visual impairment and even blindness, is a multifactorial disorder involving the dysregulation of complement, lipid, inflammation-related, angiogenesis-related, and extracellular matrix-related pathways [ 2 ]. (hindawi.com)

Furosemide Syrup 1% is indicated for the treatment of edema (pulmonary congestion, ascites) associated with cardiac insufficiency and acute noninflammatory tissue edema. (drugs.com)
As a diuretic it can be used to treat patients with intractable edema states, to increase urine flow and flush out debris from the renal tubules in patients with acute tubular necrosis, and to increase toxin excretion in patients with barbiturate, salicylate or bromide intoxication. (nih.gov)
Therefore, correction of hyponatremia should take into account the limited capacity of this adaptation mechanism to respond to acute alteration in the serum tonicity, because the degree of brain edema and consequent neurologic symptoms depend as much on the rate and duration of hypotonicity as they do on its magnitude. (medscape.com)
Myocardial edema in acute myocardial infarction (AMI) is commonly imaged using dark-blood short tau inversion recovery turbo spin echo (STIR-TSE) cardiovascular magnetic resonance (CMR). (biomedcentral.com)
As myocardial edema has long T 2 , T 2 -weighted cardiovascular magnetic resonance (CMR) imaging is usually used in the imaging of acute myocardial infarction (AMI) [ 1 , 2 , 3 ], where edema commonly occurs. (biomedcentral.com)

Contrast-enhanced T1 mapping is mostly used for calculating extracellular volume fraction (ECV) - that is, the ratio of pre- and postcontrast myocardial T1 to that of the ventricular blood compartment T1. (medscape.com)
Because ECV defines the proportion of a volume of tissue that consists of extracellular matrix or space between myocytes, it is a marker of myocardial tissue remodeling. (medscape.com)
In addition, research has been conducted concerning the use as an alternative for myocardial extracellular volume quantification 13,14 . (radiopaedia.org)
We propose here a single-shot magnetization prepared sequence that increases the contrast between edema and normal myocardium and apply it to myocardial edema imaging. (biomedcentral.com)
Transverse magnetization is sampled at the fat null point using bSSFP readout and allows for single-shot myocardial edema imaging. (biomedcentral.com)
Several CMR techniques have been proposed to address these issues of STIR-TSE for myocardial edema imaging. (biomedcentral.com)
It is robust to cardiac motion and arrhythmia and avoids the bright subendocardial rims caused by stagnant blood that mimic myocardial edema as in STIR-TSE. (biomedcentral.com)

Examples of edema in specific organs: Peripheral edema ("dependent" edema of legs) is extracellular fluid accumulation in the lower extremities caused by the effects of gravity, and occurs when fluid pools in the lower parts of the body, including the feet, legs, or hands. (wikipedia.org)
Brain edema primarily occurs as a consequence of various cerebral injuries including ischemic stroke. (benthamscience.com)
Extensive tissue swelling occurs when the third space fills with excess fluid, known as edema . (wikidoc.org)

Hypernatremia by definition is a state of hyperosmolality, because sodium is the dominant extracellular cation and solute. (medscape.com)
Urine concentration and dilution: regulation of extracellular fluid osmolarity and sodium concentration. (medlineplus.gov)
Therefore, one frequently speaks of the sodium space or the inulin space, instead of calling the measurement the true extracellular fluid volume. (brainkart.com)
Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration. (guidelinecentral.com)

Edema is swelling of soft tissues due to increased interstitial fluid. (msdmanuals.com)

A diuretic-saluretic for prompt relief of edema. (drugs.com)

Measurement of Extracellular Fluid Volume. (brainkart.com)
Edema due to extracellular fluid volume expansion is often dependent. (msdmanuals.com)

Mannitol may be useful clinically both as a diuretic and as an obligate extracellular solute. (nih.gov)

Edema, also spelled oedema, and also known as fluid retention, dropsy, hydropsy and swelling, is the build-up of fluid in the body's tissue. (wikipedia.org)
Certain organs develop edema through tissue specific mechanisms. (wikipedia.org)
Another cutaneous form of edema is myxedema, which is caused by increased deposition of connective tissue. (wikipedia.org)
In myxedema (and a variety of other rarer conditions) edema is caused by an increased tendency of the tissue to hold water within its extracellular space. (wikipedia.org)
Brain edema is a pathological phenomenon that water and brain tissue volume increase. (karger.com)
The inner border merges with the subendocardial tissue layer, which contains collagen, elastic fibers small blood vessels and nerves as well as the Purkinje fibers and connects the extracellular matrix of the myocardium to the endocardium 4 . (radiopaedia.org)
The subsequent translocation of bacterial compounds to the systemic circulation may aggravate inflammatory processes within the orbital tissue and, as a consequence, augment the proportion of activated myofibroblasts, which actively secrete extracellular matrix leading to retro-orbital tissue expansion. (frontiersin.org)
Hematoxylin is used to stain nuclei blue, while eosin stains cytoplasm and the extracellular connective tissue matrix pink. (jkt.sk)

Used in LGE assessment, gadolinium is an extracellular chelating agent that permeates the interstitial space of both normal and abnormal myocardium . (medscape.com)
A magnetization preparation module (T 2 STIR) is designed to exploit the simultaneous elevation of T 1 and T 2 in edema to improve the depiction of edematous myocardium. (biomedcentral.com)
In simulation and phantom studies, T 2 STIR-bSSFP had improved contrast between edema and normal myocardium compared with the other two edema imaging techniques. (biomedcentral.com)
T 2 STIR-bSSFP has improved contrast between edematous and normal myocardium compared with commonly used bSSFP-based edema imaging techniques. (biomedcentral.com)

patients requiring bed rest develop edema in the buttocks, genitals, and posterior thighs. (msdmanuals.com)
Women who lie on only one side may develop edema in the dependent breast. (msdmanuals.com)

extracellular RNA promoted blood coagulation and pathological thrombus formation… the paradoxical effects of innate immune sensing on different formats of mRNA vaccines are incompletely understood. (barelyablog.com)

The interstitial space could be considered to be a sub-section of the extracellular compartment. (wikidoc.org)

More often, edema develops insidiously, beginning with weight gain, puffy eyes at awakening in the morning, and tight shoes at the end of the day. (msdmanuals.com)

â ¢ Extracellular volume fraction and infarct size are the best predictors for adverse left ventricular remodeling. (bvsalud.org)

The rationale for the efficacious use of diuretic therapy is determined by the clinical pathology producing the edema. (drugs.com)
Diuretic therapy should be discontinued after reduction of the edema, or maintained after determining a carefully programmed dosage schedule to prevent recurrence of edema. (medi-vet.com)

vasogenic factors, thrombin formation, erythrocyte lysis and hemoglobin (Hb) toxicity [ 5 ] have been proved to be related to brain edema growth [ 6 ]. (karger.com)

This review focuses on the underlying mechanisms of AQP4 related to its dual role in edema formation and elimination. (benthamscience.com)

and, thus the average thickness of the extracellular matrix increased with these groups. (cdc.gov)
It has been compared to a contractile complex three-dimensional mesh, made up of myocytes merging with their neighboring cells in a nonuniform anisotropic manner supported by an extracellular collagenous matrix-forming bundle of myofibres, which are configured in a helical or spiral pattern within the two ventricles 1-4 . (radiopaedia.org)

Experimental verification of the favorable activity of synthetic corticostimulin on brain edema induced by ischemia in rats]. (nih.gov)
So, it is very important to study on the relationship between brain edema and ICH. (karger.com)
inhibition of brain edema provides favorable outcome of ICH. (karger.com)
This review mainly discusses the pathology and mechanism of brain edema, the effects of brain edema on ICH, and the methods of treating brain edema after ICH. (karger.com)
Brain edema after ICH can be divided into perihematomal edema (PHE) and intrahematomal edema. (karger.com)
Mounting evidence has demonstrated that AQP4, a water channel protein, is closely correlated with brain edema and could be an optimal therapeutic target for the reduction of ischemic brain edema. (benthamscience.com)
Deficiency of Plasminogen Activator Inhibitor Type 2 Limits Brain Edema Formation after Traumatic Brain Injury. (pai-2.com)

relatively specific for interstitial abnormalities like fibrosis and edema but is not dye-free since it uses T1 values before and after gadolinium administration) are needed. (acc.org)

Edema results from increased movement of fluid from the intravascular to the interstitial space or decreased movement of water from the interstitium into the capillaries or lymphatic vessels. (msdmanuals.com)

Diagnosis is difficult as edema may mask the substantial loss of fat and muscle mass . (seca.com)
Diagnosis is difficult to set, as edema can mask significant loss of fat and muscle mass(Extracellular) water should also be taken into account. (artbeauty.lv)

(Extracellular) water has to be taken into account. (seca.com)
Another substance that has been used to measure total body water is antipyrine, which is very lipid soluble and can rapidly penetrate cell membranes and distribute itself uniformly throughout the intracel-lular and extracellular compartments. (brainkart.com)

Distinct signs and symptoms develop quickly and include redness, thickening (edema/swelling) and ridging or orange-peel like textureof the skin - peaud'orange 4 in French. (bvsalud.org)

Furosemide is also indicated for the treatment of physiological parturient edema of the mammary gland and associated structures in cattle. (medi-vet.com)

Less often, edema results from decreased movement of fluid out of the interstitial space into the capillaries due to lack of adequate plasma oncotic pressure as in nephrotic syndrome, protein-losing enteropathy, liver failure, or starvation. (msdmanuals.com)

This can lead to edema (excess fluid in the skin and tissues). (medlineplus.gov)

Animal experiments demonstrated that fingolimod could reduce edema, cell apoptosis and cerebra atrophy and show neuroprotective function in ICH rats [ 8 ]. (karger.com)
AMD has two types: dry AMD with the presence of drusen and atrophy and wet AMD with the features of edema and hemorrhage within or below the retina or retinal pigment epithelium besides drusen and atrophy [ 3 ]. (hindawi.com)

Edema may be generalized or local (eg, limited to a single extremity or part of an extremity). (msdmanuals.com)

Current clinical treatment for ischemic edema is very limited, therefore, it is urgent to develop novel treatment strategies. (benthamscience.com)

Volume Overload Volume overload generally refers to expansion of the extracellular fluid (ECF) volume. (msdmanuals.com)

Plasminogen activator inhibitor-2 (PAI-2 / SerpinB2) inhibits extracellular urokinase plasminogen activator (uPA). (pai-2.com)

Angioedema Angioedema is edema of the deep dermis and subcutaneous tissues. (msdmanuals.com)

1 MR imaging is crucial in the identification of new lesions, which often coincide with disturbance of the BBB but that are also associated with the presence of interstitial or intramyelinic edema. (ajnr.org)
The technique is useful for single-shot edema imaging in AMI patients. (biomedcentral.com)

Edema forms more easily in dependent areas in the elderly (sitting in chairs at home or on aeroplanes) and this is not well understood. (wikipedia.org)

For long-term treatment, the dose can generally be lowered after the edema has once been reduced. (medi-vet.com)

An edema will occur in specific organs as part of inflammations, tendinitis or pancreatitis, for instance. (wikipedia.org)
Conclusions: Increased degenerative myofibers, cellular infiltrates, and edema occur temporally in response to both S-inj and L-inj. (cdc.gov)

Slowly developing edema may become massive before patients seek medical care. (msdmanuals.com)

When any one of these substances is injected into the blood, it usually disperses almost completely through-out the extracellular fluid within 30 to 60 minutes. (brainkart.com)

Anatomy11

Organisms3

Diseases29

Chemicals and Drugs10

Analytical, Diagnostic and Therapeutic Techniques and Equipment11

Psychiatry and Psychology1

Phenomena and Processes8

Health Care2

Cerebral edema20

Fluids4

Surrounding extracellular matrix2

Pulmonary edema4

Intracellular3

Inflammation8

Acute5

Myocardial7

Occurs3

Sodium4

Interstitial Fluid1

Prompt relief of edema1

Fluid volume2

Solute1

Tissue8

Myocardium4

Develop edema2

Pathological1

Compartment1

Puffy eyes1

Volume fraction1

Diuretic2

Vasogenic1

Mechanisms1

Matrix2

Brain7

Fibrosis1

Intravascular1

Diagnosis2

Water2

Symptoms1

Physiological1

Plasma1

Excess1

Atrophy2

Extremity1

Clinical1

Overload1

Inhibitor1

Tissues1

Imaging2

Dependent1

Treatment1

Occur2

Slowly1

Blood1