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Cell Line, Tumor Cell Line Tumor Cells, Cultured HeLa Cells Fibroblasts Cells, Cultured Cell Nucleus HCT116 Cells Cell Line, Transformed COS Cells NIH 3T3 Cells Cytoplasm Epithelial Cells HEK293 Cells 3T3 Cells Keratinocytes

Organisms9

Mice, Nude Mice, Knockout Mice, Inbred C57BL Mice, Transgenic Mice, Inbred BALB C Papillomaviridae Adenoviridae Drosophila Bordetella

Diseases30

Cell Transformation, Neoplastic Neoplasms Kidney Neoplasms Wilms Tumor Breast Neoplasms Osteosarcoma Carcinoma, Renal Cell Neurofibromatosis 2 Neoplasms, Experimental Adenocarcinoma von Hippel-Lindau Disease Liver Neoplasms Brain Neoplasms Colonic Neoplasms Skin Neoplasms Carcinoma, Squamous Cell Carcinoma, Hepatocellular Retinoblastoma Neoplasm Metastasis Lung Neoplasms Disease Progression Glioblastoma Mammary Neoplasms, Experimental Ovarian Neoplasms Neuroendocrine Tumors Neovascularization, Pathologic Glioma Disease Models, Animal Neuroblastoma Chromosome Deletion

Chemicals and Drugs95

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Nuclear Proteins Neurofibromin 2 Adenomatous Polyposis Coli Protein DNA-Binding Proteins Transcription Factors Cyclin-Dependent Kinase Inhibitor p16 Ubiquitin-Protein Ligases PTEN Phosphohydrolase Proto-Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p21 Cell Cycle Proteins Neoplasm Proteins Ligases Cyclins E2F Transcription Factors Repressor Proteins Proteins RNA, Messenger Tumor Markers, Biological E2F1 Transcription Factor Suppressor of Cytokine Signaling Proteins Protein-Serine-Threonine Kinases Carrier Proteins Transcription Factor DP1 Recombinant Fusion Proteins Oncogene Proteins, Viral Papillomavirus E7 Proteins RNA, Small Interfering WT1 Proteins Retinoblastoma-Binding Protein 1 Trans-Activators Retinoblastoma-Like Protein p107 Tumor Necrosis Factor-alpha DNA Primers Proteasome Endopeptidase Complex DNA, Neoplasm Hypoxia-Inducible Factor 1, alpha Subunit Membrane Proteins Cyclin-Dependent Kinases DNA Ubiquitin Recombinant Proteins Intracellular Signaling Peptides and Proteins Retinoblastoma-Like Protein p130 Phosphoric Monoester Hydrolases Antigens, Polyomavirus Transforming Apoptosis Regulatory Proteins Phosphoproteins Cytoskeletal Proteins Neurofibromin 1 beta Catenin Ubiquitins Adenovirus E1A Proteins Drosophila Proteins BRCA1 Protein Adaptor Proteins, Signal Transducing Adenovirus E1B Proteins Azides Suppressor Factors, Immunologic DNA, Complementary Adenovirus E4 Proteins Cyclin-Dependent Kinase 4 Proto-Oncogene Proteins c-myc Antineoplastic Agents MicroRNAs RNA, Neoplasm Protein Isoforms Hypoxia-Inducible Factor 1 Cyclin-Dependent Kinase Inhibitor p27 Oncogene Proteins Aquaporin 6 Proto-Oncogene Proteins c-bcl-2 Serine Cyclin-Dependent Kinase 2 Cyclin D1 Proto-Oncogene Proteins c-akt bcl-2-Associated X Protein Cysteine Endopeptidases Multiprotein Complexes Multienzyme Complexes Glutathione Transferase Enzyme Inhibitors Ubiquitin Thiolesterase Carcinogens Protein Kinases Cadherins CDC2-CDC28 Kinases Proliferating Cell Nuclear Antigen Histones

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Transfection Blotting, Western Reverse Transcriptase Polymerase Chain Reaction Tumor Burden Immunohistochemistry Models, Biological Precipitin Tests Polymerase Chain Reaction Neoplasms, Experimental Immunoblotting Transplantation, Heterologous Immunoprecipitation Two-Hybrid System Techniques Keratoplasty, Penetrating Flow Cytometry Gene Expression Profiling Cloning, Molecular Microscopy, Fluorescence Neoplasm Transplantation DNA Mutational Analysis Chromosome Mapping Chromatin Immunoprecipitation Mammary Neoplasms, Experimental Xenograft Model Antitumor Assays Oligonucleotide Array Sequence Analysis Fluorescent Antibody Technique Mutagenesis, Site-Directed Sequence Alignment Immunoenzyme Techniques Blotting, Northern Models, Molecular Disease Models, Animal

Phenomena and Processes73

Genes, Tumor Suppressor Genes, p53 Mutation Protein Binding Apoptosis Gene Expression Regulation, Neoplastic Transfection Cell Cycle Genes, Suppressor Amino Acid Sequence Base Sequence Promoter Regions, Genetic Signal Transduction Cell Proliferation DNA Damage Phosphorylation Cell Division Transcription, Genetic Transcriptional Activation Down-Regulation Protein Structure, Tertiary Gene Silencing Binding Sites DNA Methylation Loss of Heterozygosity Suppression, Genetic RNA Interference Gene Expression Regulation Gene Deletion G1 Phase Cell Aging Genes, Retinoblastoma Genes, Neurofibromatosis 2 Ultraviolet Rays Cell Survival Oncogenes Gene Expression Phenotype Ubiquitination Sequence Homology, Amino Acid Time Factors Genes, Reporter Up-Regulation Genes, APC Genes, p16 Plasmids Genes, ras Cell Differentiation S Phase Alleles Acetylation Sequence Deletion Genes, Wilms Tumor Amino Acid Motifs Gamma Rays Protein Stability Active Transport, Cell Nucleus Enzyme Activation Tumor Microenvironment Point Mutation DNA Repair Mutagenesis Exons Cell Hypoxia Genetic Vectors Protein Transport CpG Islands Cell Cycle Checkpoints Protein Processing, Post-Translational Chromosome Deletion Consensus Sequence Cell Death Dose-Response Relationship, Drug

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Genes, Tumor Suppressor Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Cell Line, Tumor Proto-Oncogene Proteins c-mdm2 Genes, p53 Mutation Molecular Sequence Data Nuclear Proteins Neurofibromin 2 Protein Binding Apoptosis Gene Expression Regulation, Neoplastic Adenomatous Polyposis Coli Protein DNA-Binding Proteins Transfection Transcription Factors Cell Line Cell Cycle Cyclin-Dependent Kinase Inhibitor p16 Ubiquitin-Protein Ligases Genes, Suppressor Tumor Cells, Cultured PTEN Phosphohydrolase Proto-Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p21 Amino Acid Sequence Base Sequence Cell Cycle Proteins Promoter Regions, Genetic Cell Transformation, Neoplastic Signal Transduction Cell Proliferation DNA Damage Phosphorylation Neoplasms Cell Division Neoplasm Proteins Ligases Cyclins Transcription, Genetic E2F Transcription Factors Repressor Proteins Proteins Transcriptional Activation Down-Regulation RNA, Messenger Blotting, Western Protein Structure, Tertiary Tumor Markers, Biological Gene Silencing Binding Sites E2F1 Transcription Factor Suppressor of Cytokine Signaling Proteins Protein-Serine-Threonine Kinases Carrier Proteins DNA Methylation Transcription Factor DP1 Loss of Heterozygosity Suppression, Genetic HeLa Cells Fibroblasts RNA Interference Kidney Neoplasms Recombinant Fusion Proteins Reverse Transcriptase Polymerase Chain Reaction Oncogene Proteins, Viral Papillomavirus E7 Proteins Gene Expression Regulation RNA, Small Interfering Cells, Cultured WT1 Proteins Gene Deletion Retinoblastoma-Binding Protein 1 Tumor Burden Cell Nucleus Trans-Activators Retinoblastoma-Like Protein p107 Tumor Necrosis Factor-alpha DNA Primers Wilms Tumor Immunohistochemistry Breast Neoplasms Proteasome Endopeptidase Complex DNA, Neoplasm G1 Phase Hypoxia-Inducible Factor 1, alpha Subunit Cell Aging Mice, Nude Models, Biological Membrane Proteins Genes, Retinoblastoma Mice, Knockout Osteosarcoma Cyclin-Dependent Kinases DNA HCT116 Cells

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