• Macrophage migration inhibitory factor (MIF) is a key regulatory cytokine within innate and adaptive immune responses, capable of promoting and modulating the magnitude of the response. (wikipedia.org)
  • MIF regulates cytokine secretion and the expression of receptors involved in the immune response. (wikipedia.org)
  • MIF (macrophage migration inhibitory factor) is a pro-inflammatory cytokine that is released during microbial infection, ARDS, rheumatoid arthritis, atherosclerosis, type 2 diabetes, and cancer. (rndsystems.com)
  • Researchers identified a cytokine, called macrophage migration inhibitory factor (MIF), along with its related protein, D-dopachrome tautomerase (D-DT), which are associated with progressive MS. These cytokines worsen the disease by increasing inflammation within the central nervous system. (neurosciencenews.com)
  • Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that plays a key role in several diseases, including cancer. (encyclopedia.pub)
  • The consequence of NF-kB activation was the dramatic increase in expression of the anti-apoptotic cytokine, macrophage migration inhibitory factor (MIF). (umaine.edu)
  • Macrophage migration inhibitory factor (MIF), a pleotropic inflammation cytokine, plays an important role in the pathophysiology of cardiovascular diseases. (tmu.edu.tw)
  • Gremlin-1 reduces macrophage formation by inhibiting macrophage migration inhibitory factor (MIF), a cytokine critically involved in atherosclerotic plaque progression and vulnerability. (leuphana.de)
  • Changes in ST mitogen-activated protein kinase (MAPK) activation were assessed by immunoblotting and mRNA expression levels of selected cytokine and chemokines in primary ST bound by iRBC were determined using real-time, reverse transcription PCR. (biomedcentral.com)
  • Macrophage migration inhibitory factor (MIF) is a mammalian cytokine that participates in innate and adaptive immune responses. (pberghei.eu)
  • Dysfunctional endothelium is a key factor in atherosclerosis that favors the increase of the expression of chemotactic and adhesion molecules (such as, intercellular adhesion molecule 1, ICAM1, and vascular cell adhesion molecule 1, VCAM1, as well as E-selectin and P-selectin) and enhanced recruitment and accumulation of monocytes [ 6 , 8 , 9 ]. (hindawi.com)
  • 2001 Fingerle-Rowson and Bucala 2001 MIF also inhibits the random migration of monocytes/macrophages the anti-inflammatory effects of glucocorticoids (Calandra et al. (acancerjourney.info)
  • 1999 MIF is usually produced by a wide variety of cell types including lymphocytes monocytes/macrophages endothelial cells and fibroblasts (Calandra and Roger 2003 Its biological effects are mediated by a receptor complex involving CD74 (Leng et al. (acancerjourney.info)
  • Here we report that Gremlin-1 is highly expressed primarily by monocytes/macrophages in aortic atherosclerotic lesions of ApoE -/- mice and is secreted from activated monocytes and during macrophage development in vitro. (leuphana.de)
  • Treatment of ApoE -/- mice with a dimeric recombinant fusion protein, m Gremlin1-Fc, but not with equimolar control Fc or inactivated m Gremlin1-Fc, reduced TNF-α expression, the content of monocytes/macrophages of atherosclerotic lesions, and attenuated atheroprogression. (leuphana.de)
  • Phagocytosis of malarial pigment hemozoin (Hz) by monocytes, macrophages, and neutrophils is a central factor for promoting dysregulation in innate inflammatory mediators. (ijbs.com)
  • Monocytes in the circulation are precursors to tissue macrophages. (msdmanuals.com)
  • Monocytes migrate into tissues, where over approximately 8 hours, they develop into macrophages. (msdmanuals.com)
  • 3 However, T-cell activation leads to CD and simultaneously enhances the secretion of cytokines such as TNF-a, IL-1, IL-3, IL-6, inhibitory factors, and macrophage migration. (drugtargetreview.com)
  • 5 T hey play a role in fixing complements, neutrophils, screen macrophages, cytokines and lymphocytes, by ligating the macrophages' Fc-c receptors, which leads to inflammation in RA. (drugtargetreview.com)
  • Cytokines expression induced by exogenous CGRP and the antagonist CGRP8-37 in A. fumigatus-exposed macrophages was evaluated by real-time PCR and ELISA. (ijo.cn)
  • As such, the role of P. falciparum -derived Hz ( Pf Hz) in mediating suppression of erythropoiesis through its ability to cause dysregulation in pro- and anti-inflammatory cytokines, growth factors, chemokines, and effector molecules is discussed in detail. (ijbs.com)
  • At infection sites, activated T cells secrete cytokines (eg, interferon-gamma [IFN-gamma]) that induce production of macrophage migration inhibitory factor, preventing macrophages from leaving. (msdmanuals.com)
  • M1, "classically activated," pro-inflammatory macrophages are stimulated by cytokines such as IFN-gamma and by various microbial components (eg, lipopolysaccharide). (msdmanuals.com)
  • M2 "alternatively activated" anti-inflammatory macrophages are stimulated predominantly by cytokines such as IL-4 and IL-13. (msdmanuals.com)
  • Ostarine increases immune system and regulates gene expression To examine the effect ostarine had on the immune system, researchers measured the effects of ostarine on the production of cytokines, inflammatory cytokines such as interferon byproducts (IFNs), and macrophage migration inhibitory factor (MAP-1), are sarms legal in usa. (marietajewelry.com)
  • Growth factors and cytokines involved in their migration, development and survival could be absent in this tissue and need further investigations. (bvsalud.org)
  • In sum, our data indicate that IL-1β is a key molecular mediator that communicates between gastro-intestinal tract (i.e. site of CDI) and bone marrow (i.e. primary neutrophil reservoir) and regulates the intensity of CDI-induced tissue neutrophilia by modulating CXCR2 expression. (frontiersin.org)
  • 1993 regulates macrophage (Calandra et al. (acancerjourney.info)
  • More recently we have demonstrated that C/EBPβ regulates the expression of several genes involved in inflammatory processes and brain injury [ 14 ] and mice lacking C/EBPβ showed a reduced inflammatory response after kainic acid injection and exhibited a dramatic reduction in pyramidal cell loss in the CA1 and CA3 subfields of the hippocampus [ 15 ]. (biomedcentral.com)
  • 4 These inflammatory mediators elicit functions of synovial tissue, including expression of metalloproteinase, proliferation and secretion of other prostaglandins, chemokines, and adhesion molecules. (drugtargetreview.com)
  • The IgA immune complex also generates excessive intra-articular tissue-growth-factor-β secretion, as well as bone erosion, which leads to RA symptoms. (drugtargetreview.com)
  • In addition, this interaction increased secretion of MIF and MIP-1α/CCL3 by ST and induced migration of PBMC towards iRBC-stimulated ST. (biomedcentral.com)
  • The supernatants were collected and analyzed for the secretion of human Fas ligand, and cells were used to determine cell death and apoptosis, cell death receptor, and intracellular proteins expression. (unisi.it)
  • and (b) contacting the hematopoietic stem cells with an agent capable of decreasing an activity or expression of CD74 and/or of macrophage migration inhibitory factor (MIF), to thereby generate hematopoietic stem cells for transplantation, and wherein the hematopoietic stem cells are not transduced with a lentivirus. (justia.com)
  • Macrophage migration inhibitory factor domain is an evolutionary conserved protein domain. (wikipedia.org)
  • This might be due to modification of the GR by means of phosphorylation as a result of activation of several kinases (p38 mitogen-activated protein kinase α, p38 mitogen-activated protein kinase γ, and c-Jun N-terminal kinase 1), which in turn might be due to reduced activity and expression of phosphatases, such as mitogen-activated protein kinase phosphatase 1 and protein phosphatase A2. (nih.gov)
  • CCAAT/enhancer-binding protein β (C/EBPβ), is a member of a family of transcription factors consisting of six structurally related basic leucine-zipper DNA-binding proteins. (biomedcentral.com)
  • Given the importance of the kidney in normal and disease states, numerous proteomic methodologies increasingly have been applied to the kidney, and novel combinations of research tools are now available to identify global changes in renal protein expression patterns induced by diseases such as diabetes. (biomedcentral.com)
  • Unlike the other MAGE family of genes whose protein expression is highly specific, NRAGE protein expression is found in most embryonic and adult tissues, suggesting a critical role in basic cellular function. (umaine.edu)
  • Matluk, Nicholas N., "Neurotrophin Receptor-Interacting Melanoma-Associated Antigen Protein Activates Nuclear Factor Kappa Beta Repressing Bone Morphogenic Protein Induced Apoptosis Through Macrophage Migration Inhibitory Factor Expression" (2011). (umaine.edu)
  • The expression levels of Bcl2 , Brain Derived Neurotrophic Factor (BDNF) and Microtubule Associated Protein 2 (MAP2) were also measured using eastern blot assay. (openaccessjournals.com)
  • CuO NPs undergo dissolution in lysosomes leading to copper-dependent macrophage cell death characterized by protein misfolding and proteasomal insufficiency. (biomedcentral.com)
  • The protein level of MIF was also tested by immunohistochemistry, and the level of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) mRNA were compared between normal, hyphae stimulated and 4-IPP pretreated groups by real-time PCR to study the influence of MIF on the expression of TNF-α and IL-6. (ijo.cn)
  • Although macrophage migration inhibitory factor (MIF) was originally identified as a lymphokine that inhibits the migration of macrophages, its ubiquitous expression suggests it may have a role beyond the immune system. (elsevierpure.com)
  • RR genotype) was associated with higher CXCR2 expression and more tissue neutrophils. (frontiersin.org)
  • and d) IL-1β neutralization reduced CXCR2 expression on bone marrow and blood neutrophils and their subsequent accrual to colonic tissue. (frontiersin.org)
  • Foxo3a was expressed in 82.1%, 78.3%, and 77.5% of neutrophils, T lymphocytes, and B lymphocytes, respectively, and statistical analysis using the Kruskal-Wallis test followed by the Steel-Dwass test showed no significant difference of Foxo3a expression among the three cell types. (go.jp)
  • During injury stimulation, the major effects on the cardiac function may be those involving mitochondria-dominated events along with potential nucleus-governed genetic/epigenetic alternations within the cardiomyocytes as well as the macrophage-led inflammation and T-cell-led immune responses underlying the myocardium-vessel interactive cascade. (hindawi.com)
  • Interleukin (IL)-9-producing subset called Th9 cell, Th22 cells which primarily secrete IL-22, IL-13 and tumor necrosis factor- and Th25 cells via producing IL-25 are believed to be important for initiating allergic reactions and developing airway inflammation. (cdc.gov)
  • It decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reducing capillary permeability. (medscape.com)
  • HDAC2 appears to mediate the action of steroids to switch off activated inflammatory genes, but in patients with COPD, patients with severe asthma, and smokers with asthma, HDAC2 activity and expression are reduced by oxidative stress through activation of phosphoinositide 3-kinase δ. (nih.gov)
  • Strategies for managing steroid resistance include alternative anti-inflammatory drugs, but a novel approach is to reverse steroid resistance by increasing HDAC2 expression, which can be achieved with theophylline and phosphoinositide 3-kinase δ inhibitors. (nih.gov)
  • Activation of synovial cell p38 MAP kinase by macrophage migration inhibitory factor. (jrheum.org)
  • Following iRBC/ST interaction, ST C-Jun N-terminal kinase 1 (JNK1) was activated and modest increases in the mRNA expression of TGF-β and IL-8/CXCL8 were observed. (biomedcentral.com)
  • Among the genes displaying significant changes in expression was complement component 3 ( C3 ), which showed a dramatic decrease in mRNA content in the hippocampus of C/EBPβ −/− mice. (biomedcentral.com)
  • In vitro, tests were conducted with C57BL/6 mice macrophages to investigate CGRP expression after interaction with A. fumigatus. (ijo.cn)
  • RESULTS: The cornea expression of CGRP was significantly elevated in C57BL/6 mice corneas and macrophages after A. fumigatus infection. (ijo.cn)
  • AIM: To determine the disparate expression of autophagy in the Aspergillus fumigatus (A. fumigatus) keratitis between susceptible C57BL/6 mice and resistant BALB/c mice. (ijo.cn)
  • The expression of autophagy-related proteins Beclin-1, LC3, SQSTM1/p62, and LAMP-1 was assessed by Western blot in C57BL/6 and BALB/c mice at 1, 3 and 5d post infection (p.i. (ijo.cn)
  • Higher expression of LAMP-1, Beclin-1, and LC3 was shown in C57BL/6 mice corneas than in BALB/c mice corneas at 1, 3 and 5d p.i., while the expression of p62 was lower in C57BL/6 mice. (ijo.cn)
  • CONCLUSION: The expression of autophagy is higher in corneas of C57BL/6 mice than in BALB/c mice after A. fumigatus infection. (ijo.cn)
  • Analyses of the course of infection of the mutant parasites in two mice strains (see 'Additional information') indicate that increased expression of Plasmodium MIF during blood-stage malaria does not increase the severity of disease but may in fact attenuate parasite virulence. (pberghei.eu)
  • Prognostic immune genes and transcription factors were used to construct an immune-related regulatory network. (biomedcentral.com)
  • 9. MMP-9 expression in meningiomas: a prognostic marker for recurrence risk? (nmuofficial.com)
  • and reduced expression of histone deacetylase (HDAC) 2. (nih.gov)
  • The working group of the Histiocyte Society divided histocytic disorders into three groups: (1) dendritic cell histiocytosis, (2) macrophage-related disorders, and (3) malignant histiocytosis. (medscape.com)
  • We also examined the expression of potential binding partners for MIF, and found that the serine protease HTRA1, known to be inhibited by MIF, was also expressed at high levels by OECs and olfactory fibroblasts in vivo and in vitro. (edu.au)
  • The mouse macrophage cell line RAW264.7 was used as an in vitro model. (biomedcentral.com)
  • Overexpression of macrophage migration inhibitory factor (MIF) was identified in human GBM specimens that were MGMT methylated but showed poor survival. (nature.com)
  • The objective of the current research was to develop and verify a Machine learning survival predictive system for CRC based on immune gene expression data and machine learning algorithms. (biomedcentral.com)
  • The INRG classification takes into account several factors, such as tumor stage and differentiation, patient age, histology, MYCN oncogene status, DNA ploidy, and segmental chromosomal anomalies, in particular chromosome 11q aberration [ 6 ] . (encyclopedia.pub)
  • Is there a rationale for switching from one anti-tumor necrosis factor agent to another? (jrheum.org)
  • Expression of tristetraprolin (G0S24) mRNA, a regulator of tumor necrosis factor-alpha production, in synovial tissues of patients with rheumatoid arthritis. (jrheum.org)
  • 5. Increased co-expression of macrophage migration inhibitory factor and matrix metalloproteinase 9 is associated with tumor recurrence of meningioma / H. Quan, Zh. (nmuofficial.com)
  • After treatment with exogenous CGRP, the levels of interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α) and IL-6 were reduced, and IL-10 level was increased in the A. fumigatus stimulated-macrophages. (ijo.cn)
  • Genetic and Phenotypic Characterization of a Salmonella enterica serovar Enteritidis Emerging Strain with Superior Intra-macrophage Replication Phenotype. (cdc.gov)
  • We have previously reported that a single nucleotide polymorphism (SNP) in leptin receptor (LEPR), present in up to 50% of people, influenced CDI-induced neutrophil CXCR2 expression and tissue neutrophilia. (frontiersin.org)
  • Inflammatory macrophages in the dog contain high amounts of intravesicular ferritin and are associated with pouches of connective tissue fibers. (cdc.gov)
  • In this study, we will examine the role of MIF in HF-induced AF arrhythmogenesis on electrical and structural remodelings (1st year), analyze the effects of MIF signaling deficiency on PV or atrial arrhythmogenesis and AF genesis in HF animal model (2nd year) and also evaluate the effect of alter MIF signaling on the expression of HDAC and non-coding RNA clusters in atrial myocytes and cardiac fibroblasts (3rd year). (tmu.edu.tw)
  • This development occurs under the influence of macrophage colony-stimulating factor (M-CSF), which is secreted by various cell types (eg, endothelial cells, fibroblasts). (msdmanuals.com)
  • 9 Overall, RA pathogenesis includes angiogenesis, synovial cell proliferation, cellular immune system activation by B- and T-cells and macrophages, and pannus formation, which results in cartilage deformation and bone erosion. (drugtargetreview.com)
  • MIF antagonist ISO-1 of 10 M, CD74 neutralized Ab of 10 g/ml, or CXCR2 neutralized Ab of 10 g/ml) on the electrical activity, ionic currents and calcium homeostasis by patch clamp, fluorescence and western blot in atrial myocytes (HL-1), and in cardiac fibroblast activity (migration, proliferation, and collagen production). (tmu.edu.tw)
  • The pathophysiological nature of MIRI is the short-term disturbance of myocardial energy and metabolism caused by reflow after ischemia and hypoxia in the coronary artery and the dynamic changes in apoptosis and the prosurvival signaling pathways in response to related injury factors. (hindawi.com)
  • In contrast, the amount of apoptosis was increased when MIF expression was ablated. (umaine.edu)
  • Macrophage migration inhibitory factor (MIF) and transforming growth factor (TGF)-β1, secreted by BeWo cells, altered the cell death and apoptosis rates in THP-1 cells. (unisi.it)
  • Results suggest that soluble factors secreted by BeWo cells induce cell death and apoptosis in THP-1 cells, and Fas/CD95 can be involved in this process. (unisi.it)
  • Herein we also show that rOos-MIF-1.1 inhibited migration of bovine macrophages and restored glucocorticoid-suppressed lipopolysaccharide (LPS)-induced TNF-α and IL-8 in human and/or bovine Isotetrandrine macrophages. (acancerjourney.info)
  • Comparison of the most abundant proteins based on normalized spectral abundance factor (NSAF) in this dataset versus a published glomerular proteome indicated enrichment of mitochondrial proteins in the former and cytoskeletal proteins in the latter. (biomedcentral.com)
  • 4. Von Randow A. J. Expression of extracellular matrix degrading proteins in classic, atypical and anaplastic meningiomas / A.J. Von Randow, S. Schindler, D.S.Tews //Pathol. (nmuofficial.com)
  • 8. Expression of cell adhesion proteins and proteins related to angiogenesis and fatty acid metabolism in benign, atypical, and anaplastic meningiomas / A.T. Panagopoulos, C.L. Lancellotti, J.C. Veiga [et al. (nmuofficial.com)
  • MIF was identified as a major regulator of atherogenesis by promoting the recruitment of mononuclear cells, activating inflammatory signaling pathways, and transdifferentiating macrophages into foam cells in the vessel wall as well as by enhancing collagenase expression and matrix degradation, the latter contributing to plaque destabilization [ 18 - 20 ]. (hindawi.com)
  • Furthermore, we identify the macrophage migration inhibitory factor (MIF) as a crucial effector of HIF1alpha that delays senescence. (ox.ac.uk)
  • Immunofluorescent staining was used to test the expression of LC3 in corneas after A. fumigatus infection. (ijo.cn)
  • In cultured THCEs stimulated by A. fumigatus, the expression of MIF became stronger in both immunohistochemistry and PCR at 16, 24, 32 and 48h post infection (p.i. (ijo.cn)
  • It has been reported that Forkhead box transcription factor class O3a (Foxo3a) is expressed in rheumatoid arthritis, a chronic inflammatory condition accompanied by bone resorption, and plays a role in its pathology. (go.jp)
  • Moreover, MIF plays a vital role in the pathophysiology of obesity, type II diabetes, and rheumatoid arthritis, which are important risk factors of AF genesis. (tmu.edu.tw)
  • 14. Dharmalingam P. Vascular endothelial growth factor expression and angiogenesis in various grades and subtypes of meningioma / P.Dharmalingam, VR Roopesh Kumar, SK. (nmuofficial.com)
  • 1 Causative factors associated with the progression of RA are environmental and genetic, and can change the shape of immunological phenomenon. (drugtargetreview.com)
  • More recently, histiocytic diseases have been reclassified into five groups: (1) Langerhans-related, (2) cutaneous and mucocutaneous, (3) malignant histiocytosis, (4) Rosai-Dorfman disease, and (5) hemophagocytic lymphohistiocytosis and macrophage activation syndrome. (medscape.com)
  • We also demonstrated that MIF mediated segregation between OECs and J774a.1 cells (a monocyte/macrophage cell line) in co-culture, which suggests that MIF contributes to the fact that macrophages are largely absent from olfactory nerve fascicles. (edu.au)
  • The deposition of Cu in lysosomes isolated from macrophages was also determined by ICP-MS. Cell viability (metabolic activity) was assessed using the Alamar Blue assay, and oxidative stress was monitored by a variety of methods including a luminescence-based assay for cellular glutathione (GSH), and flow cytometry-based detection of mitochondrial superoxide and mitochondrial membrane potential. (biomedcentral.com)
  • We observed rapid cellular uptake of CuO NPs in macrophages with deposition in lysosomes. (biomedcentral.com)
  • Specifically, a variety of other cellular populations have been identified that possess phenotypic characteristics similar to Langerhans cells, including expression of CD207 and Birbeck granules. (medscape.com)
  • Migration assays showed that MAIT cells and EM T cells migrated toward conditioned medium from placental explants. (frontiersin.org)
  • Blocking of MIF or a combination of MIF, CCL25, and CCL20 in migration assays inhibited MAIT cell migration toward placenta conditioned medium. (frontiersin.org)
  • The aim of this study was to assess the mRNA expression of MIF gene and its serum levels in the clinical manifestations of ACS and unrelated individuals age- and sex-matched with patients as the control group (CG). (hindawi.com)
  • Adhesion molecule expression leads to T-cells excessively binding to synovial-type B-cells, which finally produces large amounts of MMP. (drugtargetreview.com)
  • The physiopathological process of ACS is the atherosclerosis, the build-up of an atherosclerotic plaque starts at lesion-prone areas in large- and medium-sized arteries where the endothelium is dysfunctional, induced by cardiovascular risk factors like chronic smoking, hypertension, and permeation of macromolecules such as lipoproteins to the intima layer [ 6 , 7 ]. (hindawi.com)
  • Monocyte infiltration and macrophage formation are pivotal steps in atherosclerosis and plaque vulnerability. (leuphana.de)
  • Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the presence of cells with characteristics similar to bone marrow-derived Langerhans cells juxtaposed against a backdrop of hematopoietic cells, including T-cells, macrophages, and eosinophils. (medscape.com)
  • 5 Other factors, like cyclooxygenase, neutral proteases and nitric oxide synthase, trigger neo-angiogenesis. (drugtargetreview.com)
  • Specifically, we present novel evidence for Cu-induced SOD1 misfolding which accords with the pronounced oxidative stress observed in CuO NP-exposed macrophages. (biomedcentral.com)
  • Our results suggest that Foxo3a transcription factors may be involved in the pathogenesis of periapical granulomas. (go.jp)
  • 12. Expression of MMP-2 and -9 in short-term cultures of meningioma: influence of histological subtype / H.K. Rooprai, T.E. van Meter, S.D. Robinson [et al. (nmuofficial.com)
  • The levels of several chemokines were significantly higher in intervillous compared to peripheral blood, including macrophage migration inhibitory factor (MIF), CXCL10, and CCL25, whereas CCL21, CCL27 and CXCL12 were lower. (frontiersin.org)
  • METHODS: We collected the paraffin-embedded cornea tissues from 10 FK and 6 ocular trauma patients to explore the MIF expression by immunohistochemistry. (ijo.cn)
  • Macrophage migration inhibitory factor (MIF) is an important regulator of innate immunity with key roles in neural regeneration and responses to pathogens, amongst a multitude of other functions. (edu.au)
  • AIM: To investigate the expression of macrophage migration inhibitory factor (MIF) and detect its role in the innate immune response of fungal keratitis (FK). (ijo.cn)
  • It is not clear how the macrophage Migration Inhibitory Factor (MIF) in vivo protects neurons. (openaccessjournals.com)
  • Altogether, these results indicate that C3 is a downstream target of C/EBPβ, and it could be a mediator of the pro-inflammatory effects of this transcription factor in neural cells. (biomedcentral.com)
  • As these factors are not considered in the parabolic heat transfer equation (PHTE), the results show that the HPBTE is more accurate in predicting temperature and thermal osteonecrosis than the PHTE. (bvsalud.org)
  • RESULTS: In the corneas of FK patients, there was much stronger expression of MIF than that in the normal group showed by immunohistochemistry. (ijo.cn)
  • The potential factors involved in the migration of maternal immune cells to the placenta is still unexplored. (frontiersin.org)
  • 1994 and it upregulates Toll-like receptor 4 (TLR4) expression by immune cells (Roger et al. (acancerjourney.info)
  • AIM: To investigate the expression and role of calcitonin gene-related peptide (CGRP) in the mouse models induced by Aspergillus fumigatus (A. fumigatus). (ijo.cn)
  • We have investigated the role of the hypoxia-inducible factor 1alpha (HIF1alpha) transcription factor in preventing senescence in aerobic and hypoxic conditions. (ox.ac.uk)
  • Here we report a detailed characterization of MIF expression during mouse embryogenesis. (elsevierpure.com)