• Novagen Rosetta strains are BL21 derivatives designed to enhance the expression of eukaryotic proteins that contain codons rarely used in E. coli. (sigmaaldrich.com)
  • Zinc is also an antioxidant and can directly protect cell membrane lipids and proteins and mercaptan-dependent macromolecules (tubulin and enzyme) from oxidative damage [ 6 ]. (nature.com)
  • Initially the arrest is due to lack of sufficient cell cycle proteins to allow meiotic progression. (wikipedia.org)
  • [7] The cells that comprise the follicle, known as granulosa cells, are connected to each other by proteins known as gap junctions, that allow small molecules to pass between the cells. (wikipedia.org)
  • Eukaryotic expression vectors containing genes encoding plant proteins for killing of cancer cells. (weeksmd.com)
  • consequently, genes encoding some of these proteins are being used to design constructs for the inhibition of multiplying cancer cells. (weeksmd.com)
  • Cell proteins were analysed with 2-dimensional electrophoresis and differentially expressed proteins were identified by matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry. (who.int)
  • We speculated that the defect of protein synthesis attenuated expression of other exoglucanases or glucan synthesis-related proteins, and then induced release of Xog1p to the cell wall. (ncl.edu.tw)
  • Alternatively, spliced mRNAs typically encode distinct proteins or harbor modified cis-regulatory elements, thereby altering the level of protein expression. (unil.ch)
  • The invention describes a biotechnological method for making highly oxygen-sensitive proteins, such as nitrogenase, functional in eukaryotic cells (fungi, plants and animals). (upm.es)
  • We have learned that genes in mammalian cells are transcribed into messenger RNAs (mRNAs), which are to be translated into polypeptides (proteins). (intechopen.com)
  • Eukaryotic lipid and fatty acid metabolism remains a critical challenge for studies at the atomic, molecular and cellular scale: In contrast to simple prokaryotic systems, fatty acid metabolism in eukaryotes builds upon large multienzymes, which integrate multiple catalytic activities into giant proteins. (unibas.ch)
  • Our results suggest that in young cells Polycomb proteins are recruited to the INK4/ARF locus through CDC6 and the resulting silent locus is replicated during late S-phase. (plos.org)
  • Evidence supporting the direct control of the cell cycle by Pc-G proteins in vertebrates came from studies on mouse Bmi1 mutants. (plos.org)
  • 3. Describe regulation of proteins, chromatin structure and gene expression. (setur.fo)
  • Using RNAi screening in Drosophila cells, we identified many hnRNPs, SR proteins, core spliceosome, and transcription termination factors that control the outputs of reporter and endogenous genes. (bcm.edu)
  • The 3A and 3AB proteins were expressed in the E. coli and baculovirus expression systems. (ncl.edu.tw)
  • This HeLa cell is expressing two fluorescent proteins, including EGFP-CENP-B, a fluorescent protein that marks kinetochores (seen as paired dots oriented parallel to the x-axis and attached to opposit. (cellimagelibrary.org)
  • Our project offers a unique opportunity for Master's student to gain hands-on experience focused on transcriptional regulators with importance in expression of genes of outer membrane proteins that are essential in host-pathogen interaction. (lu.se)
  • The eukaryotic model organism Saccharomyces cerevisiae is potentially a good expression host as it tolerates several stress conditions and is known to better express insoluble proteins compared to bacterial systems. (lu.se)
  • Belongs to the eukaryotic cobalamin transport proteins family. (lu.se)
  • During your first two years, you'll explore the fundamentals of biological chemistry, molecular biology, integrative cell biology and genes and genomics. (imperial.ac.uk)
  • Target genes of interest cloned in the appropriate expression vectors are introduced into host cells. (weizmann.ac.il)
  • In addition, the expression of ERG2, ERG24 and ERG11 genes and the ergosterol content had no differences between wild type and the mutant. (ncl.edu.tw)
  • Although analyses that give information on the expression of a few genes provide insight and have been responsible for a large proportion of the bacterial pathogenesis literature currently available, our ultimate goal is to understand expression changes across the whole genome. (cdc.gov)
  • However, we now have a number of methods that allow identification of genes critical for survival in a host as well as methods that allow direct measurement of gene expression during interaction with a host. (cdc.gov)
  • Two of these methods, signature-tagged mutagenesis and in vivo expression technology, do not directly measure gene expression and do not allow true genomic-scale analysis, but they have been devised to identify genes necessary for pathogens during real infections. (cdc.gov)
  • During her PhD, Isabel studied the regulation of the alternative splicing of the Fibronectin (FN1) and Lamin A/C ( LMNA ) genes, and their role in host cell invasion (1) , aging (2) and metabolism (3,4) . (unil.ch)
  • One basic problem is how a decrease in tRNA levels, by downregulating Pol III efficiency, influences the expression pattern of protein-coding genes. (mdpi.com)
  • For example, steroid and thyroid hormones directly bind to nuclear receptors, which induce expression of specific genes. (intechopen.com)
  • In other words, expression of specific genes might have relevance to pathogenesis of diseases. (intechopen.com)
  • Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. (jove.com)
  • Thus, reporter genes "report" the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell. (jove.com)
  • The El-Deiry Research Team concluded in their Oncotarget Research Output that surprisingly, there were no genes that correlated with BRCA1 mRNA expression uniquely in BC, but there were several genes that correlated with BRCA1 expression uniquely in CRC. (news-medical.net)
  • This loss is accompanied with an increased expression of the histone demethylase Jmjd3 and with the recruitment of the MLL1 protein, and correlates with the expression of the Ink4a/Arf genes. (plos.org)
  • 10. Describe and categorize cellular signaling pathways, including the transfer of a stimulus across a cell membrane, and how the stimulus is propagated to its effector, it be an enzyme or one or several genes. (setur.fo)
  • Deep sequencing has revealed thousands of eukaryotic protein-coding genes that defy the central dogma, producing circular noncoding RNAs rather than linear messenger RNAs. (bcm.edu)
  • In total, these results indicate that inhibition or slowing of canonical pre-mRNA processing events shifts the steady-state output of protein-coding genes towards circular RNAs, which likely helps explain why and how circular RNAs show tissue-specific expression profiles. (bcm.edu)
  • Complex behavior within eukaryotic cells manifest from layered regulatory networks changing the transcription of many genes. (atcc.org)
  • To systematically study these pathways by modulating individual components-or in the case of synthetic biology, building new network architectures by creating DNA circuit-it is critical to control multiple genes simultaneously under tightly regulated or inducible expression. (atcc.org)
  • However, prior to lineage commitment, genes are primed at low expression levels. (lu.se)
  • However, prior to commitment, it has been cells, it is evident that GATA-1 and PU.1 are able to specify observed that many genes are expressed at intermediate or basal erythroid and myeloid cell fates (see [16] and references therein). (lu.se)
  • The transcription factors regulated by eIF2α control the activity of genes involved in processes that help reduce the stress on the cell. (medlineplus.gov)
  • A second group of methods, which includes DNA microarrays and proteomics, have advantages that overcome the limitations implicit in signature-tagged mutagenesis and in vivo expression technology, namely, the ability to directly measure expression (gene or protein) levels on a true genome-wide scale, but their application to analysis of bacterial pathogens during real infections is still in its infancy. (cdc.gov)
  • ALGENTECH has developed proprietary molecular tools for editing the genome of eukaryotic cells. (prnewswire.com)
  • In addition to new methods of nuclear genome editing, ALGENTECH is a pioneer in the transformation of the mitochondrial genome and the development of self-replicative molecules for multigenic expression in chloroplasts with vast fields of application, particularly in synthetic biology. (prnewswire.com)
  • The account expands to include a brief discussion of other regulatory mechanisms that govern the expression of lambda's genome. (the-scientist.com)
  • For example, the genome in each eukaryotic cell is tightly packed by sharply bending DNA around nucleosome and, similarly, DNA bending by transcription factors is a common cellular mechanism that participates in the regulation of gene expression. (lanl.gov)
  • Both crRNA-tracrRNA duplexes and sgRNAs can be used to target SpCas9 for multiplexed genome editing in eukaryotic cells 1 , 3 . (cdc.gov)
  • Gene expression must be appropriately maintained to regulate development, differentiation, and proliferation of cells. (intechopen.com)
  • The mTORCs integrate multiple input signals from nutrient levels, cellular energy state and external growth factors for the control of anabolic vs. catabolic metabolism, proliferation and growth as well as cytoskeletal dynamics and cell survival. (unibas.ch)
  • Due to their central role in driving cell proliferation, mTORCs are key targets for anti-cancer therapy. (unibas.ch)
  • Oncotarget published 'Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients' which reported that LMNB2 is a chromatin remodeling protein that also plays a role in eukaryotic cell proliferation by organizing the nuclear membrane during mitosis. (news-medical.net)
  • LMNB2 is a chromatin remodeling protein that also plays a role in eukaryotic cell proliferation by organizing the nuclear membrane during mitosis. (news-medical.net)
  • Cellular senescence is a fundamental cellular program that is activated after a finite number of cell divisions and operates to avoid further cell proliferation. (plos.org)
  • PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration. (nih.gov)
  • Transcriptional activation of Proteasome 26S non-ATPase subunit 7 by forkhead box P3 participates in gastric cancer cell proliferation and apoptosis. (nih.gov)
  • Hypoxia inducible factor-2α importance for migration, proliferation, and self-renewal of trunk neural crest cells. (lu.se)
  • In mammalian cells, active and silent rDNA promoters are characterized by specific histone modifications, DNA methylation, and positioning of the promoter-bound nucleosome (reviewed in reference 22 ). (asm.org)
  • These include bacterial system and three eukaryotic systems, such as yeast, insect and mammalian cells. (weizmann.ac.il)
  • Molecular mechanisms of the initiation of transcription from TATA box have been well known as the most essential nuclear events in mammalian cells. (intechopen.com)
  • An animation that takes the viewer inside a mammalian cell where one can see the nucleus and its characteristic envelope connected to the endoplasmic reticulum. (cellimagelibrary.org)
  • Moreover, we show that the Polycomb protein BMI1 interacts with CDC6, an essential regulator of DNA replication in eukaryotic cells. (plos.org)
  • Mechanisms for maintaining genetic information during cell division and the generation of genetic variation: replication, mitosis, meiosis, recombination. (lu.se)
  • However, there is limited information on the function of circRNA in oral squamous cell carcinoma (OSCC). (hindawi.com)
  • Oral squamous cell carcinoma (OSCC) is the third most common cancer in developing countries and ranks sixth among systemic cancers worldwide [ 1 , 2 ]. (hindawi.com)
  • The organisation and evolution of the eukaryotic genomes. (lu.se)
  • Characterisation of the chromatin structures and dynamic mechanisms in human and murine cells and as well in the Malaria causing parasite Plasmodium falciparum. (uni-regensburg.de)
  • It then goes on to extrapolate from these mechanisms to possible developmental decisions made in eukaryotic cells. (the-scientist.com)
  • Mechanisms regulating INK4/ARF expression are not fully characterized. (plos.org)
  • The molecular mechanisms of other cellular processes like protein sorting and distribution, membrane transport, cytoskelet function and basic processes of cell signalling are also emphasised. (cuni.cz)
  • give basic review over the regulatory mechanisms of the cycle, and mechanisms for controlled cell death. (setur.fo)
  • The molecular mechanisms potentially responsible for cadmium -induced cell transformation and tumorigenesis were investigated using Balb/c-3T3 cells transformed with cadmium chloride. (cdc.gov)
  • In particular, we are interested in exploring novel mechanisms involved in regulation of eukaryotic gene expression. (pewtrusts.org)
  • Molecular mechanisms for regulation of gene expression at different levels: remodeling of chromatin, initiation of transcription, nuclear transport and signalling, and RNA interference. (lu.se)
  • Mechanisms that regulate development from single cell to multicellular organisms. (lu.se)
  • Lluis Fajas at UNIL and investigated the role of the cell cycle regulator CDK4 in metabolism. (unil.ch)
  • Her contributions place as a key molecular hub, that regulates key signaling pathways to coordinate cell metabolism and cellular function and overall promote anabolism in the context of cycling cells and in differentiated tissues (6-8) . (unil.ch)
  • Responding to the Environment (Signal Processing and its Relationship to Cell Structure, Metabolism and Gene Expression). (nhbs.com)
  • Metabolism in eukaryotic cells is tightly regulated in response to nutrient and energy availability as well as growth factor signaling for coordination of metabolism across organs and organism. (unibas.ch)
  • Internal State and Gene Expression (Transcription and its Control). (nhbs.com)
  • Hsa_circ_001242 expression levels in 40 paired OSCC tissues and four OSCC cell lines were selected using real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR). (hindawi.com)
  • Determination and inference of eukaryotic transcription factor sequence specificity. (bvsalud.org)
  • Transcription factor (TF) DNA sequence preferences direct their regulatory activity, but are currently known for only â ¼1% of eukaryotic TFs. (bvsalud.org)
  • Sequences matching both measured and inferred motifs are enriched in chromatin immunoprecipitation sequencing ( ChIP-seq ) peaks and upstream of transcription start sites in diverse eukaryotic lineages. (bvsalud.org)
  • You will also employ functional assays investigating host-pathogen interactions in vitro, such as serum bactericidal assay or adherence to eukaryotic cells. (lu.se)
  • Using the SURVEYOR nuclease assay 13 , we assessed the ability of each Cas9-sgRNA complex to generate indels in human embryonic kidney (HEK) 293FT cells through the induction of DNA doublestranded breaks (DSBs) and subsequent nonhomologous end joining (NHEJ) DNA damage repair (Online Methods). (cdc.gov)
  • 100 predicted genomic off-target loci in 293T and 293FT cells. (cdc.gov)
  • Genomic profiling of primary diffuse large B-cell lymphoma of the central nervous system suggests novel potential therapeutic targets. (cdc.gov)
  • Background: Bone marrow mesenchymal stem cells (BMSCs) are easy to isolate and amplify in vitro, and easy for transferring and expressing of exogenous gene. (ox.ac.uk)
  • The authors first draw on recent advances in cell and molecular biology to develop an account of the living state that applies to all organisms (and only to organisms). (nhbs.com)
  • The expression of nitrogenase in the mitochondrial matrix overcomes the main difficulty in producing nitrogen-fixing cereals: the presence of molecular oxygen derived from photosynthesis. (upm.es)
  • Molecular Cell Biology (Lodish et al. (cuni.cz)
  • Molecular biology of the Cell (Alberts et al. (cuni.cz)
  • To provide the students with knowledge of cell structure and function, organelles, growth and cell cycle, and cellular and molecular interactions. (setur.fo)
  • Expression host strains for pETBlue and pTriEx vectors are lDE3 lysogens that also carry the compatible pLacI plasmid, encoding the lac repressor. (sigmaaldrich.com)
  • Eukaryotic expression plasmid was constructed after cytosine deaminase gene was cloned on pIRES2-AcGFP1 plasmid. (ox.ac.uk)
  • Such methods generally comprise providing a cell with one or more precursor nucleic acid sequences that encode two or more RNA molecules. (genomeweb.com)
  • We performed northern blot analyses for the guide RNA truncations and found increased levels of expression for the longer tracrRNA sequences, suggesting that improved target cleavage was at least partially due to higher sgRNA expression or stability ( Fig. 1c ). (cdc.gov)
  • Here, we characterize SpCas9 targeting specificity in human cells to inform the selection of target sites and avoid off-target effects. (cdc.gov)
  • Published 29 December 2018 The baculovirus-insect cell expression system has become one of the most widely used eukaryotic expression systems for heterologous protein production in many laboratories. (lu.se)
  • or (f) living vectored cells expressing specific heterologous antigens. (who.int)
  • The invention relates to a method for inhibiting the expression of a target gene in a eukaryotic cell," the patent's abstract states. (genomeweb.com)
  • The patent, its abstract states, relates to "duplex oligonucleotide complexes [that] can be administered to a cell, tissue or organism to silence a target gene without the aid of a transfection reagent. (genomeweb.com)
  • Bacterial toxin-antitoxin (TA) systems serve a variety of physiological functions including regulation of cell growth and maintenance of foreign genetic elements. (nih.gov)
  • Our previous cell and animal experiments confirmed that zinc supplementation could activate Nrf2 and up-regulate its downstream antioxidant factors, thus reducing oxidative damage to renal tubular epithelial cells and kidney tissues [ 11 ]. (nature.com)
  • Central to this investigation is an understanding of what gene products are required and expressed during a natural infection and how this expression changes over time (from initial colonization to causation of disease and spread of the pathogen to new hosts) and space (in different cells or tissues within the host). (cdc.gov)
  • 12. Describe two major types of tissues (connective and epithelial tissues), the concept of cellular communities and their organization (like communication between cells and the adhesion between cells), and show how stem cells maintain and renew tissues. (setur.fo)
  • We first confirmed that hsa_circ_001242, which is located at chr10: 17157441-17168917 (Figure 1 ), was significantly downregulated in OSCC cell lines and OSCC tissues. (hindawi.com)
  • Its expression levels in tissues at various stages of OSCC were then explored, and the potential relationship between hsa_circ_001242 expression levels and patients' clinicopathological factors were investigated. (hindawi.com)
  • Strategies for gene therapy and production of medicines via genetically-modified organisms (expression vectors and viral vectors). (lu.se)
  • The growth-regulating Doc toxin exhibits structural similarity to secreted virulence factors that are toxic for eukaryotic target cells. (nih.gov)
  • The pattern and timing of gene expression can be determined by creating recombinant DNA with a reporter gene under the control of a cis -regulatory sequence of interest and introducing it into cells or an organism. (jove.com)
  • Since the gene of interest and the reporter gene have the same cis -regulatory sequence, they are expressed in the same cells and at the same time. (jove.com)
  • For example, to study the expression of β-tubulin in C. elegans , the coding sequence of the β-tubulin gene was replaced by the gfp gene. (jove.com)
  • Almost any sequence can now be efficiently circularized in eukaryotic cells, which has enabled us (and others) to begin to ask how circular RNAs function. (bcm.edu)
  • Broadly sampling DNA -binding domain (DBD) types from multiple eukaryotic clades, we determined DNA sequence preferences for >1,000 TFs encompassing 54 different DBD classes from 131 diverse eukaryotes . (bvsalud.org)
  • We find that closely related DBDs almost always have very similar DNA sequence preferences, enabling inference of motifs for â ¼34% of the â ¼170,000 known or predicted eukaryotic TFs. (bvsalud.org)
  • Immunostained whole mount retinas following optic nerve crush (ONC): upregulation of injury marker, pcJun, demonstrates activation of injury signaling pathways resulting in retinal ganglion cell (RGC) death following ONC. (pharmoptima.com)
  • Moreover, we anticipate that our system will allow for the controlled study of multi-step pathways by enabling manipulation of single protein expression. (atcc.org)
  • Design, time and setting: The single sample cell gene engineering experiment was performed at the Dalian Research & Development Center for Stem Cells and Tissue Engineering, Dalian University of Technology from March 2006 to April 2007. (ox.ac.uk)
  • Stem cells. (setur.fo)
  • Maintaining multipotent trunk neural crest stem cells as self-renewing crestospheres. (lu.se)
  • In vitro maintenance of multipotent neural crest stem cells as crestospheres. (lu.se)
  • The Concept of Cancer Stem Cells: Elaborating on ALDH1B1 as an Emerging Marker of Cancer Progression. (lu.se)
  • Numerous vectors have been engineered for the sole purpose of killing cancer cells, and some have successfully suppressed malignant tumours. (weeksmd.com)
  • C. albicans Hom6p thus had an effect on cell survival and cell adhesion by maintaining protein synthesis and cell wall function. (ncl.edu.tw)
  • High expression of LMNB2 in CRC tumors correlates with worse disease-free cumulative and overall survival, and that knocking out the LMNB2 gene allowed for the development of CRC tumors through a mechanism that involved silencing of p21 expression. (news-medical.net)
  • 2021) Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients. (news-medical.net)
  • These play critical roles in cell growth and survival, differentiation, embryonic development, and their related pathologies, including oncogenic transformation. (pewtrusts.org)
  • Extra copy number of BCL2 is correlated with increased BCL-2 protein expression and poor survival in diffuse large B-cell lymphoma treated with chemoimmunotherapy. (cdc.gov)
  • Oxygen sensing across eukaryotic kingdoms and their roles in complex multicellularity. (lu.se)
  • Peripheral blood mononuclear cells of healthy donors and post-transplant lymphoma patients were stimulated with or without lunasin in the presence of IL-12 or IL-2. (weeksmd.com)
  • The myocardium often has diffuse fibrosis, with a small number of mononuclear cells scattered throughout. (medscape.com)
  • Laboratory demonstrations of cell culture, and laboratory exercises elucidating some cellular processes and some methods in cell biology, including use of light microscopy and epifluorescence microscopy. (setur.fo)
  • Gene regulation in developmental biology and the cell cycle. (lu.se)
  • In addition, NK cells stimulated with lunasin plus cytokines displayed higher tumoricidal activity than those stimulated with cytokines alone using in vitro and in vivo tumor models. (weeksmd.com)
  • We seek to identify novel epigenetic regulators and characterize their roles in controlling the patterns of epigenetic codes during normal cell differentiation and tissue development. (pewtrusts.org)
  • Unlike prokaryotes, which do not have a nucleus, eukaryotic cells have a membrane-bound nucleus that contains the cell's genetic material. (proprofs.com)
  • Eukaryotes are likely the most recently evolved type of cell because they are more complex and have a nucleus, which prokaryotes lack. (proprofs.com)
  • These characteristics suggest that eukaryotes have undergone more evolutionary changes and adaptations over time compared to prokaryotes, making them the most recently evolved cell type. (proprofs.com)
  • Ingredients of the Simplest Cells (Prokaryotes and the Sizes of their Contents). (nhbs.com)
  • Unfortunately, RoF proved toxic to human cells due to its conversion to analogs of flavin coenzymes. (biomedcentral.com)
  • To reduce potentially toxic effect on the host cell, the growth and production phases were separated by using the inducible promoter GAL1p to control recombinant gene expression. (lu.se)
  • Expression is screened on a small scale in 4-10 ml cultures and soluble and insoluble cellular fractions are analyzed by SDS-PAGE for protein expression. (weizmann.ac.il)
  • 9. Examine and explain structure, functions and components of cellular membranes, including transport of molecules and ions across membranes and the importance of such transport in cell homeostasis and neuronal signaling. (setur.fo)
  • 13. Contrast cancer cells and normal cells, and show how cancer behaves and disobeys the 'rules' of the normal cellular community. (setur.fo)
  • A marked host inflammatory reaction characterized by local accumulation of polymorphonuclear leukocytes, lymphocytes, and plasma cells is associated with these areas of cellular destruction. (medscape.com)
  • Sustaining and Changing the Internal State (The Interrelationship between Gene Expression and the Cell?s Current Composition and Functional State). (nhbs.com)
  • Lipid compositions reflect the metabolic and functional state of a cell. (unibas.ch)
  • A landmark example are giant eukaryotic fatty acid synthases (FASs), which comprise seven types of functional domains and carry out more than 40 reaction steps for the biosynthesis of fatty acids from acetyl- and malonyl-CoA. (unibas.ch)
  • Functional analyses of ectopically expressed copies of the variant miRNA precursors demonstrate loss of function, gain of function, and altered expression levels. (genomeweb.com)
  • Tumor Necrosis Factor Alpha Antagonism Reveals a Gut/Lung Axis That Amplifies Regulatory T Cells in a Pulmonary Fungal Infection. (uc.edu)
  • Zinc Induces Dendritic Cell Tolerogenic Phenotype and Skews Regulatory T Cell-Th17 Balance. (uc.edu)
  • Gene therapy has attracted attention for its potential to specifically and efficiently target cancer cells with minimal toxicity to normal cells. (weeksmd.com)
  • Mechanistic studies of the toxicity of zinc gluconate in the olfactory neuronal cell line Odora. (uc.edu)
  • This recombinant gene is introduced into different cell types, and both the gene of interest and the reporter gene are allowed to express. (jove.com)
  • we also demonstrate that Hom6p can localize at cell wall by western blot. (ncl.edu.tw)
  • Our findings demonstrate, for the first time, that the cell transformation and tumorigenesis induced by cadmium are due, at least in part, to the overexpression of TEF-1delta, a novel cadmium -responsive proto-oncogene. (cdc.gov)
  • L'équipe Beagle, représentée par Vincent Liard, David Parsons, Jonathan Rouzaud-Cornabas et Guillaume Beslon s'est vue décerner le prix du meilleur article lors de la conférence internationale ALife 2018 (International Conference on Artificial Life) en Juillet 2018 à Tokyo pour leurs travaux sur l'évolution de la complexité. (cnrs.fr)
  • Given that OKSM (Yamanaka) factors convert somatic cells into induced pluripotent stem (iPS) cells, alterations in transcriptional state could affect destiny of the cells. (intechopen.com)
  • Conclusion: pIRES2-AcGFP1-CD eukaryotic expression vector has been successfully transfected into BMSCs, which indicates that BMSCs can be an ideal vector for cytosine deaminase gene therapy. (ox.ac.uk)
  • A 31-kDa protein was detected in eukaryotic cells transfected with an expression vector containing the TEF-1delta cDNA. (cdc.gov)
  • In addition, we found that C. albican Hom6p has an effect on cell adhesion, which is important for C. albicans virulence. (ncl.edu.tw)
  • methods for reducing the expression level of a target gene. (genomeweb.com)
  • Methods for analysis of gene expression: microarray, hybridisation, promoter analyses. (lu.se)
  • Crush injury to the optic nerve severs the retinal ganglion cell (RGC) axons leading to the gradual death of RGC neurons in the retina. (pharmoptima.com)
  • Differential display analysis of gene expression revealed consistent and reproducible overexpression of a transcript in the transformed cells compared with the nontransformed cells. (cdc.gov)
  • Oocyte meiosis, important to all animal life cycles yet unlike all other instances of animal cell division, occurs completely without the aid of spindle -coordinating centrosomes . (wikipedia.org)
  • Surprisingly, when spliceosome components were depleted or inhibited pharmacologically, the steady-state levels of circular RNAs increased while expression of their associated linear mRNAs concomitantly decreased. (bcm.edu)
  • In all cases, the parasites have successfully entered various cells of the body and formed pseudocysts, each containing hundreds to thousands of amastigotes. (medscape.com)