Exposure gestational age association between maternal maternal age. Medical search. Frequent questions

Maternal smoking during pregnancy is an established risk factor for low infant birth weight, but evidence on critical exposure windows and timing of fetal growth restriction is limited. (plos.org)
Here we investigate the associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth by triangulating evidence from 3 analytical approaches to strengthen causal inference. (plos.org)
We analysed data from 8,621 European liveborn singletons in 2 population-based pregnancy cohorts (the Generation R Study, the Netherlands 2002-2006 [ n = 4,682]) and the Born in Bradford study, United Kingdom 2007-2010 [ n = 3,939]) with fetal ultrasound and birth anthropometric measures, parental smoking during pregnancy, and maternal genetic data. (plos.org)
A consistent linear dose-dependent association of maternal smoking with fetal growth was observed from the early second trimester onwards, while no major growth deficit was found in women who quit smoking early in pregnancy except for a shorter FL during late gestation. (plos.org)
Maternal smoking during pregnancy is an established risk factor for low infant birth weight. (plos.org)
We analysed data from 8,621 white European liveborn singletons from 2 population-based pregnancy cohorts to assess the associations of maternal quitting, reducing, and continuing smoking during pregnancy with the longitudinal growth of different fetal parameters (weight, head circumference, femur length, and abdominal circumference). (plos.org)
This study aimed to determine if hypothyroidism prior to, or during, pregnancy increases the risk of attention-deficit hyperactivity disorder (ADHD) in the child and how the association may be modified by preterm birth, sex of the child, and race-ethnicity. (nih.gov)
Gestational diabetes mellitus (GDM) is defined as glucose intolerance of variable degree with onset or first recognition during pregnancy. (medscape.com)
Gestational diabetes mellitus accounts for 90% of cases of diabetes mellitus in pregnancy, while preexisting type 2 diabetes accounts for 8% of such cases. (medscape.com)
The US Preventive Services Task Force (USPSTF) recommends screening for gestational diabetes mellitus after 24 weeks of pregnancy. (medscape.com)
Women with prediabetes identified before pregnancy should be considered at extremely high risk for developing gestational diabetes mellitus during pregnancy. (medscape.com)
An association between VOC-contaminated drinking water and adverse late pregnancy outcomes is plausible, but further investigation is needed. (cdc.gov)
Despite, or perhaps because of, heightened attention to the use of antidepressants during pregnancy over the past decade, the management of prenatal maternal depression has become increasingly controversial. (psychiatrictimes.com)
The relative risk of fetal exposure to maternal depression versus that of antidepressant medication remains poorly defined because of our reliance on a patchwork conglomeration of case series, pregnancy registries, and observational studies with inconsistent levels of control for potentially confounding exposures. (psychiatrictimes.com)
However, we can confirm previous findings of perinatal determinants as high maternal pre-pregnancy BMI, and smoking during pregnancy being risk factors for childhood overweight. (nih.gov)
Children whose mothers had a higher exposure to certain phthalates during pregnancy tend to show smaller total gray matter in their brains at age 10 . (neurosciencenews.com)
The study also found that maternal exposure to plasticizers during pregnancy is associated with lower child IQ at age 14, which confirmed the results of two previous study on the topic. (neurosciencenews.com)
Phthalate exposure of mothers was assessed using urine samples collected during pregnancy. (neurosciencenews.com)
Higher maternal concentrations in urine during pregnancy of monoisobutyl phthalic acid (mIBP), a metabolite of diisobutyl phthalate (DIBP), were associated with smaller white matter only in girls. (neurosciencenews.com)
The new study estimates that 18% of the total effect of phthalate exposure in pregnancy on children's IQ could be explained by changes in gray matter volumes in both boys and girls. (neurosciencenews.com)
Few, if any, studies examine prenatal air pollution exposure and these pregnancy outcomes in neonates born to the same women. (biomedcentral.com)
The within-woman comparison implemented here better controls for factors that may differ between women and potentially confound the relationship between PM 2.5 exposure and pregnancy outcomes. (biomedcentral.com)
Exposure to ambient air pollution during pregnancy may increase risk of lower birthweight percentile for gestational age. (biomedcentral.com)
First, most studies of PM 2.5 exposure during pregnancy compare exposure and pregnancy outcomes in different women. (biomedcentral.com)
To the best of our knowledge, there are no population-based studies of prenatal PM 2.5 exposure and SGA or birthweight percentile for gestational age in the United States that compare successive pregnancy outcomes in the same mother. (biomedcentral.com)
This study aimed to evaluate the effect of maternal pregestational type 1 diabetes on the presence of fatty liver in offspring and the association between maternal BMI, glycemic control during pregnancy, offspring metabolic risk factors, and offspring level of soluble CD163 (sCD163) (a marker of macrophage activation) and risk of fatty liver. (ku.dk)
Maternal metabolite concentrations during pregnancy were related to child concentrations at ages 1-3 years. (cdc.gov)
Parental emotion regulation in the early postpartum period moderated the association between pregnancy-specific pandemic worries and child socioemotional development such that pregnancy-specific pandemic worries did not relate to worse child socioemotional development among parents with high (B = - .02, SE = .10, t = - .14, p = .89) levels of emotion regulation. (bvsalud.org)
Exposure to each pollutant was estimated for each woman individually throughout her pregnancy and for each trimester. (who.int)
We conclude that exposure to air pollution during pregnancy may be associated with LBW. (who.int)
Logistic regression analysis was con- nal malnutrition and anaemia, maternal km of a unique air pollution monitor- ducted to examine the predictive effect of age, weight gain during pregnancy as ing station, were aged 18-35 years and air pollution on LBW. (who.int)
Individual exposure during pregnancy was assessed by LUR models and Kriging interpolation. (biomedcentral.com)
During the study period, the average individual exposure concentration of PM 2.5 during the entire pregnancy was 84.54 μg/m 3 . (biomedcentral.com)
For the PTB subgroup, the hazard of PM 2.5 exposure during pregnancy was stronger for very preterm births (VPTB) than moderate preterm births (MPTB). (biomedcentral.com)
Moreover, women who had less than 9 years of education or who conceived during the cold season tended to be more susceptible to the PM 2.5 exposure during pregnancy. (biomedcentral.com)
Maternal lifestyle affects both mother health and pregnancy outcome in humans. (puppyreading.com)
Several studies have demonstrated that interventions oriented towards reducing stress and anxiety have positive effects on pregnancy complications such as preeclampsia, excessive gestational weight, gestational diabetes and preterm birth. (puppyreading.com)
Furthermore, we found that EE modulates maternal metabolism and produces an anti-inflammatory environment that contributes to pregnancy maintenance. (puppyreading.com)
CONCLUSION: Moderate exposure to arsenic contaminated drinking water early in pregnancy was associated with increased odds of experiencing nausea/vomiting and abdominal cramping. (oregonstate.edu)
Preventing exposure to arsenic contaminated drinking water during pregnancy could improve maternal health. (oregonstate.edu)
Maternal alcohol intake prior to and during pregnancy and risk of adverse birth outcomes: evidence from a British cohort. (alcoholresearchforum.org)
This paper aimed to investigate the association between alcohol intake before and during pregnancy with birth weight and gestational age and to examine the effect of timing of exposure. (alcoholresearchforum.org)
There have been literally hundreds of epidemiologic studies relating the maternal use of alcohol during pregnancy and outcomes among the offspring. (alcoholresearchforum.org)
these are often classified as FAE only if there is evidence of alcohol use by the mother during pregnancy, but otherwise blamed on some other exposure. (alcoholresearchforum.org)
We prospectively investigated refined-grain intake during pregnancy in association with offspring growth through age 7 y among high-risk children born to women with gestational diabetes mellitus (GDM). (fabresearch.org)
Higher maternal refined-grain intake during pregnancy was significantly related to a greater BMIZ and a higher risk of overweight or obesity at age 7 y among children born after pregnancies complicated by GDM. (fabresearch.org)
We evaluated the association between 11 urinary phthalate metabolites and GDM, impaired glucose tolerance (IGT), and continuous blood glucose concentration during pregnancy in The Infant Development and Environment Study (TIDES). (researcher-app.com)
Outcomes included birth weight, pregnancy loss, preterm birth, small for gestational age, and a composite outcome composed of the latter four components plus abruption. (uthscsa.edu)
Gestational diabetes mellitus (GDM), a common pregnancy complication, continues to be a significant public health and clinical problem. (springer.com)
The report states that dosage modification may be needed during pregnancy because of the expanded maternal blood volume, increased glomerular filtration rate, increased hepatic metabolism and sequestration of the drug in the fetal compartment. (aafp.org)
We aimed 1) to address confounding by indication, as well as socioeconomic and environmental factors associated with depression and 2) evaluate associations of timing of SSRI exposure in pregnancy with the risk of preterm birth and related outcomes (small for gestational age and low birthweight) among women with depression before pregnancy. (providence.org)
We accounted for maternal/pregnancy characteristics, pre-pregnancy comorbidity/depression severity, social vulnerability, rural health disparity, and pre-natal depression severity. (providence.org)
Women with no SSRI order during pregnancy (n=3,122) constituted the unexposed group (no SSRI exposure group). (providence.org)
Conclusions These findings suggest associations between preterm birth/low birthweight and SSRI exposure is dependent on exposure timing during pregnancy. (providence.org)
Conclusion Maternal perinatal and early-life factors including antibiotics in pregnancy and childhood, gestational diabetes, prenatal smoking, C-section and summertime birth, and hospitalisations for respiratory illness are associated with partly or uncontrolled childhood asthma. (bmj.com)
Previously we found that certain fetal imprinted genes represented as an allele score are associated with maternal pregnancy glucose concentrations. (biomedcentral.com)
Recently it was reported that fetal polymorphisms with strong associations with birth weight tend to mediate these independently of increases in maternal pregnancy glucose concentrations. (biomedcentral.com)
Genetics can have roles in regulating both maternal glucose concentrations in pregnancy and fetal growth expressed as offspring birth weight. (biomedcentral.com)
We recently reported associations between fetal imprinted genes represented as an allele score and both gestational diabetes and maternal glucose concentrations in late pregnancy [ 6 ]. (biomedcentral.com)
In the current study we therefore examined relationships between our fetal imprinted gene allele score and measures of size at birth, in particular investigating whether any allele score associations with size at birth appear to be attenuated by maternal glucose concentrations in pregnancy. (biomedcentral.com)
In addition to the promotion of healthy gestational weight gain, rising levels of obesity worldwide are increasing the pressure to emphasise the importance of entering pregnancy at a healthy weight. (endocrinology.org)
However, there is also evidence to suggest that exposure to obesity in pregnancy can increase a child's risk of non-communicable disease in adulthood. (endocrinology.org)
Obesity in pregnancy is associated with a plethora of complications in the mother that may include gestational diabetes, pre-eclampsia, inflammation and elevated lipid profiles. (endocrinology.org)
Those interested in understanding the impact of maternal obesity often feed high fat/high sugar diets prior to conception and throughout pregnancy and lactation. (endocrinology.org)
The Food Consumption Frequency Questionnaire showed to be a good instrument to be considered clinically as well as for research purposes with Brazilian pregnant women, this tool capable of properly measuring food intake is fundamental for establishing health conditions during pregnancy, helping to assess the association between diet, nutrition and health. (bvsalud.org)
Adequate nutrition during the gestational period may favor the development and fetal growth promoting a better pregnancy outcome 1,2 . (bvsalud.org)

A health statistics review uses existing health data from data sources like birth certificates and health registries to determine whether health outcomes in a particular community are occurring at a higher, lower, or about the same level compared to statewide or national levels after taking into account factors such as gender and age of individuals within the community. (cdc.gov)
A health statistics review does not tell us why elevations or deficits in certain health outcomes exist and can not prove a cause and effect relationship between exposure to chemicals and health outcomes. (cdc.gov)
Because it relies on previously existing data, a health statistics review may not be able to take into account certain individual risk factors such as medical history, smoking, genetics, and occupational exposures which may explain the elevations or deficits in health outcomes. (cdc.gov)
Although there was no evidence of associations found between SGA and the air pollutants mentioned in these studies, the results contribute to the body of literature assessing maternal exposure to ambient air pollution and adverse birth outcomes. (cdc.gov)
As the evolving literature examining birth outcomes increasingly recognizes their multifactorial nature, Dr. Keiser seeks to understand the complex interactions between genetics, environmental context, maternal age and racial/ethnic background that drive both outcomes and disparities. (hopkinsmedicine.org)
We analyzed birth outcomes in the east Minneapolis-St. Paul metropolitan area from 2002 to 2011, where a portion of the population faced elevated exposure to PFASs due to long-term contamination of drinking water supplies from industrial waste disposal. (biomedcentral.com)
Our findings provide evidence of a causal relationship between filtration of drinking water containing high levels of exposure to PFASs and improved reproductive outcomes. (biomedcentral.com)
In the face of public concern over mounting evidence that PFASs are associated with adverse human health outcomes, the U.S. Environmental Protection Agency recently released a plan to revisit federal exposure standards [ 4 ]. (biomedcentral.com)
Some studies have identified relationships between PFAS exposure and reproductive outcomes, although the evidence regarding the pathway and significance of associations is mixed. (biomedcentral.com)
This paper provides new evidence of the effect of PFOA and PFOS exposure on reproductive outcomes. (biomedcentral.com)
Findings from studies of prenatal exposure to pesticides and adverse birth outcomes have been equivocal so far. (mdpi.com)
While the observed associations between DDT and such outcomes might not be causal, the studies are not so flawed that the observations can be dismissed out of hand. (cdc.gov)
In this study we investigated whether these joint introductions of tobacco control policies in the Netherlands were associated with changes in key perinatal outcomes known to be associated with maternal smoking and/or SHS exposure. (nature.com)
Maternal use of selective serotonin reuptake inhibitors, fetal growth, and risk of adverse birth outcomes. (erasmusmc.nl)
We expected the association between greenness and birth outcomes to disappear once we accounted for other environmental exposures such as air pollution and noise. (thebump.com)
Objective:To determine the association between preeclampsia and a range of adverse neurodevelopmental outcomes in offspring after excluding preterm births. (puppyreading.com)
Main Outcomes and Measures:Associations between preeclampsia in term pregnancies and cerebral palsy, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), epilepsy, intellectual disability, and vision or hearing loss using multivariable logistic regression. (puppyreading.com)
Evidence is conflicting regarding the relationship between low maternal alcohol consumption and birth outcomes. (alcoholresearchforum.org)
In secondary analyses, most other phthalates were not found to be related to study outcomes, though some associations were noted. (researcher-app.com)
Given the prevalence of phthalate exposures and the growing evidence of associations with metabolic outcomes, future studies should continue to examine this question in diverse cohorts of pregnant women, particularly in those who may be at higher risk for GDM and IGT. (researcher-app.com)
Background: Maternal sensitivity, or high quality maternal caregiving, in which the mother leads and structures the infant's early experiences in a responsive way, is associated with improved child development outcomes and health, both in the immediate and long term, and thus an important area of public health research. (columbia.edu)
Aim: This study investigates the association of several factors: (1) maternal depressive symptomology, (2) breastfeeding, (3) concurrent maternal alcohol intake and (4) infant biological vulnerability upon outcomes of (1) Maternal Sensitivity and (2) Infant Cognitive Development, as well as their effect on the association between senstivity and cognitive development. (columbia.edu)
Objective: To assess whether functional maternal or fetal genotypes along well-characterized metabolic pathways (ie, CYP1A1, GSTT1, and CYP2A6) may account for varying associations with adverse outcomes among pregnant women who smoke. (uthscsa.edu)
Cocaine-exposed infants with birth weight below the 10th percentile for gestational age and gender and those placed with kinship caregivers are at increased risk for less optimal developmental outcomes. (erowid.org)

Birth certificate data that contained information on maternal and infant characteristics were obtained from the Texas Department of State Health Services (TX DSHS). (cdc.gov)
In addition, she is using the Boston Birth Cohort to explore associations between maternal prenatal and perinatal exposures and the risk of infant necrotizing enterocolitis, and understand the extent to which these associations vary by race/ethnicity. (hopkinsmedicine.org)
Assuming that these associations are causal, we estimated the increase in infant deaths that might result from DDT spraying. (cdc.gov)
We attempted to estimate the consequences for infant deaths if maternal DDT exposure in fact increases preterm births and decreases the duration of lactation with the strength of association seen in North America. (cdc.gov)
If, on the other hand, the estimated increases in infant death rates are similar to or larger than the expected benefits, whether the association is causal matters a great deal, and further investigation is warranted, especially in areas where DDT is reintroduced. (cdc.gov)
A low birth weight can be caused either by a preterm birth (low gestational age at birth) or the infant being small for gestational age (slow prenatal growth rate), or a combination of both. (wikipedia.org)
A very large birth weight is usually caused by the infant having been large for gestational age. (wikipedia.org)
To this aim, I investigate the short- and long-term consequences of maternal, foetal and infant health on brain development later in life (structure, function, cognition and behaviour). (erasmusmc.nl)
The present study, while not large (1,303 pregnant women) evaluated reported alcohol intake to birth weight and the risk that an infant is small for gestational age (SGA). (alcoholresearchforum.org)
No associations were observed between refined-grain intake and infant growth. (fabresearch.org)
Are maternal depression, breastfeeding, maternal alcohol intake and infant biological vulnerability effect modifiers or confounders of the maternal sensitivity and infant cognitive development association? (columbia.edu)
Although previous research has established that exposure to high maternal sensitivity advances the outcome of infant cognitive development, factors such as breastfeeding, which is hypothesized to confound the association, or depression, which is negatively associated with sensitivity, have not yet been examined together in a single study. (columbia.edu)
The majority of infant studies examining the maternal sensitivity-infant cognition association include either normal birth weight infants or LBW infant samples. (columbia.edu)
Univariate and multi-variable regression analyses were used to examine whether the four maternal factors were associated with Maternal Sensitivity, measured by the Nursing Child Assessment Teaching Scale (NCATS), and with Cognitive Development, measured by the Bayley Scale of Infant Development, Research Edition (BSF-R). (columbia.edu)
Conclusion: This research demonstrates that an independent association between maternal sensitivity and infant cognitive development remains even after adjusting for breastfeeding, and that breastfeeding is a separate means to advancing infant cognitive development. (columbia.edu)
I have received federal funding for my research through multiple mechanisms, including a BIRCWH K12 award, an R40 from HRSA/Maternal Child Health Bureau, and most recently an AHRQ R18 to implement and evaluate a group well child care intervention for mother-infant dyads affected by maternal opioid use disorder. (nemours.org)
County-level Variation in Infant Mortality Reporting at Early Previable Gestational Ages. (nemours.org)
In a prospective, longitudinal study of 203 urban term infants, 3 cocaine exposure groups were defined by maternal report and infant meconium assay: unexposed, heavier cocaine exposure (75th percentile self-reported days of use or meconium benzoylecognine concentration), or lighter cocaine exposure (all others). (erowid.org)
Examiners, masked to exposure history, tested infants at 6, 12, and 24 months of age with the Bayley Scales of Infant Development. (erowid.org)
There were no significant adverse main effects of level of cocaine exposure on Mental Development Index (MDI), Psychomotor Development Index (PDI), or Infant Behavior Record. (erowid.org)
Heavier prenatal cocaine exposure is not an independent risk factor for depressed scores on the Bayley Scales of Infant Development up to 24 months of age when term infants are compared with lighter exposed or unexposed infants of the same demographic background. (erowid.org)

Multivariable Cox regression was applied to examine associations with perinatal. (lu.se)
CONCLUSION: This study finds support for fetal origins of endometriosis, in that exposure to adverse environment or restricted development during the perinatal period may increase the risk. (lu.se)
Primary outcome measures were: perinatal mortality, preterm birth and being small-for-gestational age (SGA). (nature.com)
Through reducing maternal smoking and SHS exposure, tobacco control policies have considerable potential to benefit perinatal health. (nature.com)
We undertook a national quasi-experimental study, which involved analysing the association between the 2004 and 2008 joint introduction of tobacco control policies and perinatal mortality, preterm birth and SGA births using monthly data from a comprehensive dataset of singleton births in the Netherlands between 2000 and 2011. (nature.com)
BACKGROUND: The etiology of autism is unknown, although perinatal and neonatal exposures have been the focus of epidemiologic research for over 40 years. (harvard.edu)
Objective: To provide the first review and meta-analysis of the association between perinatal and neonatal factors and autism risk. (harvard.edu)
Methods: PubMed, Embase, and PsycInfo databases were searched for studies that examined the association between perinatal and neonatal factors and autism through March 2007. (harvard.edu)
ConclUSIONS: There is insufficient evidence to implicate any 1 perinatal or neonatal factor in autism etiology, although there is some evidence to suggest that exposure to a broad class of conditions reflecting general compromises to perinatal and neonatal health may increase the risk. (harvard.edu)
This study evaluated associations between perinatal and early-life factors and early childhood asthma control. (bmj.com)
Associations between perinatal and early-life factors and risk of partly and uncontrolled asthma were evaluated by multinomial logistic regression. (bmj.com)

METHODS: This total-population register-based cohort study consisted of 628 312 singleton women born in Sweden between 1973 and 1987, who were followed for diagnosed endometriosis from age 15 years until the end of 2012. (lu.se)
This cohort study examined the relationship between VOC exposure and fetal growth retardation (measured as SGA and decreased MBW) and preterm delivery in three groups with different exposures to contaminated drinking water and in an unexposed comparison population. (cdc.gov)
IMPACT STATEMENT: In this well-established cohort, we evaluated the patterns of urinary OPE metabolites in children ages 1-8 years. (cdc.gov)
ABSTRACT This historical cohort study was designed to clarify the association between air pollution and low birth weight (LBW) amongst women referred to Tehran hospitals in 2007. (who.int)
A prospective cohort in Leeds, UK, of 1303 pregnant women aged 18-45 years. (alcoholresearchforum.org)
Methods: Using data from the Early Childhood Longitudinal Study-Birth (ECLS-B) Cohort, a nationally representative sample of U.S. born children, depressive symptomology was evaluated as an effect-modifier, and breastfeeding was evaluated as a confounder of the sensitivity-cognitive development association. (columbia.edu)
This study assessed the associations between a wide range of prenatal and early-life factors and the level of asthma control achieved at the preschool age in a population-level cohort. (bmj.com)

Our data suggest that increased fetal exposure to active maternal glucocorticoids may program later systolic blood pressure. (umass.edu)
Sulfonamides have not been reported to cause neonatal kernicterus as a result of fetal exposure at any gestational age. (aafp.org)
Fetal exposure to nitrofurantoin has not been reported to cause hemolytic anemia in the newborn, and metronidazole has not been associated with an increase in birth defects or subsequent cancer. (aafp.org)

abstract = 'Abstract OBJECTIVE Intrauterine exposure to maternal type 1 diabetes is associated with a less favorable metabolic profile later in life. (ku.dk)
Abstract Background Incidence rates of colorectal cancer (CRC) are increasing among younger adults and in mid-life, implicating exposures in early life as risk factors. (deepdyve.com)
abstract = "Background: Maternal behaviors and exposures affect fetal growth and development. (syr.edu)

Here, we assess whether prenatal exposure to ambient fine particulate matter (PM 2.5 ) is associated with small-for-gestational-age (SGA) birth or birthweight percentile for gestational age in a longitudinal setting. (biomedcentral.com)
Here, we present a sibling-matched case-control study of 227,948 newborns to identify an association between fire-sourced fine particulate matter (PM 2.5 ) and birthweight in 54 LMICs from 2000 to 2014. (stencila.io)

She has been examining trends at the population level through analyses using a statewide database from California, focusing first on preterm birth, and with plans to extend the analyses to examine both low birth weight and small for gestational age births. (hopkinsmedicine.org)
Title : Association of Maternal Body Mass Index, Excessive Weight Gain, and Gestational Diabetes Mellitus With Large-for-Gestational-Age Births Personal Author(s) : Kim, Shin Y.;Sharma, Andrea J.;Sappenfield, William;Wilson, Hoyt G.;Salihu, Hamisu M. (cdc.gov)
We then estimate the effect of that exposure on the frequency of preterm births and on duration of lactation. (cdc.gov)
Multiple births, where a mother has more than one child at one time, can also be a determinant in birth weight as each baby is likely to be outside the AGA (appropriate for gestational age). (wikipedia.org)
However, in models that did not account for births to the same mother, statistically significant associations were observed between some PM 2.5 exposure windows and higher odds of SGA and lower birthweight percentile among NHB women. (biomedcentral.com)
such as maternal age, maternal edu- mortality, and has been established as a Data on all singleton term births cation, maternal job, socioeconomic determinant of neonatal mortality [1]. (who.int)
Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring. (puppyreading.com)

However, exposure assessment methods relying on monitors have the potential to cause exposure misclassification due to a lack of spatial variation. (biomedcentral.com)
The CHDS provides a unique opportunity to study impacts of early life by linking in-utero exposures with cancers ascertained from a population-based registry.18,19 Materials and methods Study population The CHDS was established in 1959 and recruited nearly all (98%) pregnant women receiving prenatal care from the Kaiser Foundation Health Plan (Oakland, CA) between June 1959 and September 1966, with deliveries through June 1967. (deepdyve.com)
Methods We conducted propensity score-adjusted regression to calculate odds ratios (OR) of preterm birth, small for gestational age, and low birth weight. (providence.org)
Methods This retrospective study used administrative health data from mothers and children born 2010-2012 with a diagnosis of asthma before age 5 years, in Alberta, Canada. (bmj.com)

Large birth weight can be caused by maternal health issues such as gestational diabetes and obesity. (wikipedia.org)
Altered early growth likely influences the metabolic syndrome pathway, with obesity and T2D both occurring at a younger age [ 7 ]. (nature.com)
Emerging animal data suggest that in utero exposure to dietary refined carbohydrates may predispose offspring to an obese phenotype, indicating a potential role for nutritional programming in the early origins of obesity, but intergenerational human data are lacking. (fabresearch.org)
Problem: Prenatal exposure to metabolic dysregulation arising from maternal obesity can have negative health consequences in post-natal life. (elsevierpure.com)
To date, the specific effects of maternal obesity on fetal immunity at a cellular level have not been well characterized. (elsevierpure.com)
Conclusion: This study demonstrates an association between maternal obesity and fetal immunity. (elsevierpure.com)
2 As birth weight is only an indirect indicator of maternal and/or fetal health, specific exposures have been investigated which include maternal undernutrition during periods of famine, glucocorticoid exposure due to premature birth and, most recently, maternal over-nutrition and obesity. (endocrinology.org)
A number of human studies have investigated the long term impact of exposure to maternal obesity. (endocrinology.org)
While human studies are vital, the prevalence of maternal obesity in these populations is relatively low, considering these mothers were pregnant 50-60 years ago. (endocrinology.org)
The laboratory where I am based utilises a mouse model of maternal diet-induced obesity. (endocrinology.org)

We also found that an estimated 26% of the association between maternal smoking and early-onset endometriosis could be explained by birthweight-for-gestational age. (lu.se)
We examined prenatal exposure to agricultural pesticides in relation to preterm birth and term low birthweight, respectively, in children born between 1998 and 2010, randomly selected from California birth records. (mdpi.com)
PM 2.5 ) and small-for-gestational-age (SGA) birth and lower birthweight percentile for gestational age. (biomedcentral.com)
Associations between PM 2.5 exposure and birthweight percentile and odds of SGA birth were calculated using linear and generalized mixed models, comparing successive pregnancies to the same woman. (biomedcentral.com)
Among NHB women, statistically significant within-woman associations between PM 2.5 , SGA, and birthweight percentile were not observed. (biomedcentral.com)
This adds to the evidence that PM 2.5 exposure may be causally related to SGA and birthweight percentile, even at concentrations close to or below National Ambient Air Quality Standards. (biomedcentral.com)
We determined the associations of the within-group variations in LFS exposure with birthweight differences between matched siblings using a fixed-effects regression model. (stencila.io)

Small for gestational age is defined as below the 10th percentile for gestational age and sex. (wikipedia.org)
10th percentile was associated with lower PDI scores for children with heavier cocaine exposure and with lower MDI scores for all groups. (erowid.org)

The impact of maternal depression on the fetus. (psychiatrictimes.com)

This observational study suggests a possible association between exposure to aluminum in some childhood vaccines and development of persistent asthma in children. (cdc.gov)
Incidence rate differences (IRDs), adjusted hazard ratios (aHRs), and their 95% confidence intervals (CIs) were estimated to evaluate the association of maternal hypothyroidism with childhood ADHD risk. (nih.gov)
The association of maternal hypothyroidism with childhood ADHD was influenced by timing of diagnosis. (nih.gov)
To explore the association of maternal T2D and gestational diabetes mellitus (GDM) with childhood anthropometry, and the influence of maternal BMI on these associations. (nature.com)
Exposure to Maternal Depressive Symptoms in Fetal Life or Childhood and Offspring Brain Development: A Population-Based Imaging Study. (erasmusmc.nl)
We investigated associations between maternal postpartum distress covering anxiety, depression and stress and childhood overweight. (nih.gov)
Outcome was childhood overweight at 7-years-of age. (nih.gov)
Maternal postpartum distress is apparently not an independent risk factor for childhood overweight at 7-years-of-age. (nih.gov)
In other words: exposure to plasticizers before birth could lead to smaller total gray matter in childhood, which in turn could be related to a lower IQ. (neurosciencenews.com)
BACKGROUND: Organophosphate esters (OPEs) have replaced flame retardant polybrominated diphenyl ethers as flame retardants in consumer products, but few longitudinal studies have characterized childhood OPE exposure. (cdc.gov)
We examined the associations of average maternal OPE metabolite concentrations with OPE metabolite concentrations in childhood, characterized childhood OPE trajectories with latent class growth analysis (LCGA), and examined factors related to trajectory membership. (cdc.gov)
Average maternal urinary BCEP and BDCIPP were associated with concentrations in early childhood. (cdc.gov)
BCEP, BDCIPP, and DPHP demonstrated different trajectories in children, which suggests that multiple samples may be required to capture OPE exposure patterns in childhood. (cdc.gov)
No evidence was found of a significant association between other maternal and neonatal factors and childhood type 1 diabetes. (biomedcentral.com)
In Scotland, between 1984 and 2003 the incidence of childhood type 1 diabetes increased by 2.6% per year, and this rise has been greater in children aged under 5 years [ 2 ]. (biomedcentral.com)
However, the evidence on the role of many maternal and neonatal factors in the development of childhood type 1 diabetes is inconclusive and only one study has presented data on the Scottish population [ 5 ]. (biomedcentral.com)

CONCLUSIONS Intrauterine exposure to maternal type 1 diabetes and higher maternal prepregnancy BMI may predispose to fatty liver in the offspring. (ku.dk)
CONCLUSIONS: The results indicated that only boys show a significant association between IQ scores and sleep duration. (ku.dk)

Associations between ambient levels of combustion pollutants and small for gestational age infants in Texas. (cdc.gov)
There is scant evidence regarding the associations between ambient levels of combustion pollutants and small for gestational age (SGA) infants. (cdc.gov)
The main objective of the project presented was to determine associations between combustion pollutants and SGA infants in Texas using three different exposure assessments. (cdc.gov)
The median gestational age of NICU infants was 36 weeks, median birth weight was 2.2 kg and 49.5% were delivered by non-elective caesarean section. (who.int)
Strength of the association was strongest in preterm born infants, boys, and Hispanic children. (nih.gov)
And fewer infants from these areas were considered small for their gestational age. (thebump.com)
Using the LBW category may result in potential misclassification since this group combines at least two different phenomena and includes infants who have had either compromised gestational time as in the case of small for gestational age (SGA), or insufficient gestational time, as in the case of premature birth, or both. (columbia.edu)
However, none of these studies examine the association between sensitivity and cognitive outcome in infants exclusively premature or SGA. (columbia.edu)
Shimura and colleagues report on two Japanese infants who developed hypothyroidism requiring levothyroxine treatment after exposure to iodinated contrast media. (endocrine.org)
Hokken-Koelega and coauthors describe an international consensus guideline on treatment of infants and older children small for gestational age, including discussion of newly identified genetic and epigenetic causes. (endocrine.org)

OBJECTIVE: We aimed to examine the exposure pattern of urinary OPE metabolites in children. (cdc.gov)
OBJECTIVE: Maternal colonization with Group B Streptococcus (GBS) is a significant risk factor for serious neonatal morbidity. (bvsalud.org)

BACKGROUND: Arsenic, a common groundwater pollutant, is associated with adverse reproductive health but few studies have examined its effect on maternal health. (oregonstate.edu)
Several epidemiological studies have shown adverse effects of LFS exposure on human health. (stencila.io)

Therefore, it is necessary to divide PTB into three categories and examine the relationships between prenatal PM 2.5 exposure and PTB subtypes. (biomedcentral.com)

Stratified analyses were used to evaluate whether the association is affected by timing of first diagnosis, gestational age at birth (term vs. preterm), sex, and race-ethnicity. (nih.gov)
Exposure to maternal hypothyroidism during the periconceptual period significantly increases the risk of ADHD and that the association varies with gestational age at delivery, child sex, and race-ethnicity. (nih.gov)

Univariate regression analyses showed that of the measures of biological vulnerability, premature birth had the greatest association with both sensitivity and cognitive development in comparison to the LBW or SGA. (columbia.edu)

The statistical analysis revealed an association between higher gestational concentrations of monoethyl phthalate (mEP) and smaller total gray matter volumes in offspring at age 10. (neurosciencenews.com)
In 2020 and 2021, the Generation R Study reported that maternal prenatal urinary concentrations of phthalates were associated with lower non-verbal IQ at age 6 years. (neurosciencenews.com)
RESULTS: Bis(2-chloroethyl) phosphate (BCEP) had the lowest median concentrations over time (0.66-0.97 mg/L) while the median concentrations of bis(1,3-dichloro-2-propyl) phosphate (BDCIPP) increased with age (1.44-3.80 mg/L). The median concentrations of diphenyl phosphate (DPHP) fluctuated between 1.96 and 2.69 mg/L. Intraclass correlation coefficients for urinary metabolites measured at five time points indicated high variability within individuals (0.13-0.24). (cdc.gov)
SIGNIFICANCE: The trajectory analysis showed different patterns of urinary OPE metabolite concentrations, suggesting the need to collect multiple samples to adequately reflect OPE exposure. (cdc.gov)
We therefore investigated whether potential associations between the fetal allele score and birth weight were related to maternal glucose concentrations in the Cambridge Baby Growth Study. (biomedcentral.com)
This association was partially attenuated by adjusting for maternal glucose concentrations (β = 50 (4-95) g/risk allele, β′ = 0.089, p = 0.03, n = 405). (biomedcentral.com)
The large for gestational age at birth association was also partially attenuated by maternal glucose concentrations. (biomedcentral.com)
However none of the fetal variants used to construct the gene score in this study were independently associated with maternal glucose concentrations. (biomedcentral.com)

Gestational exposure to LFS was assessed in each newborn using the concentration of fire-sourced PM 2.5 . (stencila.io)

A health statistics review can take risk factors such as age, race and sex that are commonly found on health records into account. (cdc.gov)
The study consisted of 326,991 children and found that cumulative exposure to aluminum from vaccines during the first two years of life was associated with a small increased risk of persistent asthma in children ages 2-5 years. (cdc.gov)
Lower gestational age, lower birth weight, delivery by caesarean section and birth in the month of May were statistically significant risk factors for NICU admission. (who.int)
Maternal hypothyroidism increases the risk of ADHD diagnosis in the offspring. (nih.gov)
We investigated the associations of maternal and birth characteristics with risk of endometriosis among Swedish women of reproductive age. (lu.se)
Researchers furthered this study and found that maternal stressful events that occur prior to conception have a negative impact on birth weight as well, and can result in a higher risk for preterm and lower birth weight babies. (wikipedia.org)
In-utero hyperglycemia exposure influences later cardiometabolic risk, although few studies include women with pre-existing type 2 diabetes (T2D) or assess maternal body mass index (BMI) as a potential confounder. (nature.com)
For example, even though glucocorticoids are recommended to women at risk of preterm birth to accelerate fetal lung maturation [ 2 ], a growing body of evidence indicates that prenatal glucocorticoid exposure induces a variety of adult diseases, including hypertension [ 3 - 5 ]. (hindawi.com)
That is, it is unclear whether observed associations reflect causal effects, as the women with the highest exposures may have other risk factors. (biomedcentral.com)
We found significant associations between increasing maternal prepregnancy BMI, being born large for gestational age, offspring level of sCD163, as well as offspring metabolic risk factors (decreasing adiponectin and HDL cholesterol and increasing leptin, HOMA of insulin resistance, and HOMA of insulin secretion) and degree of fatty liver. (ku.dk)
In this study, we utilized a land use regression (LUR) model to assess individual exposure, and explored the association between PM 2.5 exposure during each time window and the risk of preterm birth in Wuhan city, China. (biomedcentral.com)
Logistic regression analyses were conducted to determine the association between women exposure to PM 2.5 and the risk of different subtypes of PTB. (biomedcentral.com)
Maternal exposure to PM 2.5 increased the risk of PTB, and this risk was stronger for VPTB than for MPTB, especially during the first trimester. (biomedcentral.com)
A previous study found that different subtypes of PTB, defined by gestational age, have been associated with different risk factors, including air pollution [ 15 ]. (biomedcentral.com)
The aim of this study was to investigate maternal and neonatal risk factors for type 1 diabetes in children under 15 years old in Grampian, Scotland. (biomedcentral.com)
Conditional logistic regression was used to evaluate the association between various maternal and neonatal factors and the risk of type 1 diabetes. (biomedcentral.com)
Many investigators have focussed on the relationship between maternal and neonatal factors and the subsequent risk of type 1 diabetes. (biomedcentral.com)
We examined the association between in-utero exposure to antibiotics and risk of CRC in adult offspring. (deepdyve.com)
In this prospective study of more than 18 000 mother-child dyads, in-utero exposure to long-acting sulfonamides increased risk of colorectal cancer in adult offspring. (deepdyve.com)
Although long-acting sulfonamides are no longer routinely prescribed in humans, their continued presence as environmental pollutants raise the possibility that long-term exposure may also increase risk of colorectal cancer. (deepdyve.com)
Early life, beginning in utero, represents a critical window of susceptibility,4 and exposures during this time can translate into large effects on risk of cancer in adulthood. (deepdyve.com)
Despite the mounting epidemiological evidence demonstrating an association between maternal DEHP exposure and increased risk for preterm birth, the mechanisms underlying these relationships are unclear. (biomedcentral.com)
Risk factors for gestational diabetes: is prevention possible? (springer.com)
For example, it was observed that exposure to perfluorooctanoic acid (PFOA), an endocrine disruptor often found in some carpet cleaning liquids, microwave popcorn bags and some cooking ware was positively related to GDM risk [ 10 ]. (springer.com)
The allele score was also positively associated with risk of being large for gestational age at birth (odds ratio 1.60 (1.19-2.15) per risk allele, p = 2.1 × 10 −3 , n = 660) and negatively associated with risk of being small for gestational age at birth (odds ratio 0.65 (0.44-0.96) per risk allele, p = 0.03, n = 660). (biomedcentral.com)
Awareness of the concept that your environment in utero and early postnatal life is important for future disease risk came about from observational studies that showed a positive association between geographical areas of high neonatal mortality and ischaemic heart disease in adulthood. (endocrinology.org)

Conclusion Our findings support an association between in-utero exposure to long-acting sulfonamides and CRC in adulthood. (deepdyve.com)
And Jee and coauthors summarize recent findings on the associations between early infantile growth, the timing of puberty, and metabolic risks. (endocrine.org)
Our findings indicate that gestational exposure to LFS harms fetal health. (stencila.io)

This project is the first to look at SGA and combustion pollutants in the Southern United States with three different exposure metrics. (cdc.gov)

If the associations are causal but the estimated effect on death rates is very small compared to the plausible benefits from vector control, then whether the associations are causal does not impact public health decisions. (cdc.gov)
Despite small individual differences in brain volume and IQ, the widespread exposure to phthalates and lax regulations present a significant public health concern. (neurosciencenews.com)
Sensitivity analyses indicated possible strong race-specific associations in Asians, though these results are based on a small sample size (n = 35). (researcher-app.com)
Small for gestational age is not associated with SSRI exposure. (providence.org)

The research underscored that the connection between phthalate exposure and reduced IQ was partly due to alterations in gray matter volumes. (neurosciencenews.com)
Additional phthalate metabolites were also found to be linked to glucose intolerance, with possible stronger associations in certain racial/ethnic subgroups. (researcher-app.com)
Following oral exposure, DEHP is quickly metabolized by gut lipases to its active metabolite, monoethylhexyl phthalate (MEHP), and excreted in the urine. (biomedcentral.com)

however, median gestational age and birth weight were higher than in developed countries. (who.int)
Wave 1 follow-up included 423 children, aged 1.5-5 years (median follow-up age 2.5 years). (nature.com)

The authors of this study concluded that for any level of maternal glucose concentration fetal genetics has a major impact on growth but acts predominantly through mechanisms independent of maternal glucose. (biomedcentral.com)

Using mixed effects regression models to control for BP measurement conditions, maternal and child characteristics, we examined the association between the F/E ratio and child BP. (umass.edu)

Phthalates are common plasticizer chemicals that have been linked to glucose intolerance in the general population, but there is only limited research on their association with gestational diabetes (GDM). (researcher-app.com)
These results suggest that associations between the fetal imprinted gene allele score and size at birth are mediated through both glucose-dependent and glucose-independent mechanisms. (biomedcentral.com)

Intrauterine cannabis exposure affects fetal growth trajectories: the Generation R Study. (erasmusmc.nl)
Well-Child Care Adherence After Intrauterine Opioid Exposure. (nemours.org)
Subsequent studies further investigated and supported these associations using low birth weight as a proxy marker of a poor intrauterine environment. (endocrinology.org)

Adjustment for maternal BMI strengthened the negative association between GDM and child weight, BMI and circumferences. (nature.com)
Maternal T2D was no longer associated with greater child mean skinfolds ( p = 0.14) or waist circumference ( p = 0.18) after adjustment for maternal BMI. (nature.com)
Linear and Poisson regressions were used, with adjustment for maternal demographic, lifestyle, and dietary factors. (fabresearch.org)

Greater maternal antenatal BMI was associated with increased anthropometric measures in offspring independent of maternal glycemic status. (nature.com)

A). Modification of the association between smoking and outcome by genotype was evaluated. (uthscsa.edu)

Average birth weight and average gestational age were statistically significantly lower in the highly exposed population than in the control area prior to filtration of municipal water supply. (biomedcentral.com)

Clinical decision making must consider the well-being of the mother, fetus, and even older children who can be adversely impacted by active maternal psychopathology. (psychiatrictimes.com)

Foetal genes influence how the fetus grows in utero, and the maternal genes influence how the environment affects the growing fetus. (wikipedia.org)
Animal data show that decreased activity of placental 11-beta-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which potently inactivates glucocorticoids (e.g. cortisol) to inert forms (cortisone), allows increased access of maternal glucocorticoids to the fetus and 'programs' hypertension. (umass.edu)

Multiple logistic regression models were used to determine the associations between combustion pollutants and SGA. (cdc.gov)
The association with timing of the tobacco control policies was investigated using interrupted time series logistic regression analyses with adjustment for confounders. (nature.com)
Exposures were modelled as categorical variables using inter-quartile ranges in a logistic regression model. (who.int)

A better understanding of contributing factors and mechanisms controlling untimely labor is necessary to prevent preterm birth and to improve maternal and fetal health. (biomedcentral.com)

Study limitations include measurement error due to maternal self-report of smoking and the modest sample size for MR analyses resulting in unconfounded estimates being less precise. (plos.org)
Prenatal tobacco exposure and brain morphology: a prospective study in young children. (erasmusmc.nl)
A previous study of ours showed that prenatal dexamethasone (DEX) exposure induces hypertension in adult offspring, which is driven by renal programming [ 8 ]. (hindawi.com)
A new study linked higher prenatal exposure to certain phthalates with reduced gray matter in children's brains by age 10. (neurosciencenews.com)
Maternal alcohol use, associated with both breastfeeding and depression, has not been examined in any study investigating the sensitivity-cognitive development association. (columbia.edu)
A recent study conducted by the US Centers for Disease Control found measureable levels of MEHP in 80 % of urine samples analyzed, suggesting that exposure to DEHP is widespread in the U.S. population [ 10 ]. (biomedcentral.com)
Study design: One hundred adults (ages 18-40), who were singletons born at term (37-42 weeks), participated. (syr.edu)
In a birth weight-related genome wide association study (GWAS) Beaumont et al. (biomedcentral.com)
Furthermore, due to their shorter lifespans, they allow the study of age-associated conditions. (endocrinology.org)

There is a complex relationship between a baby's genes and the maternal environment that the child is developing in. (wikipedia.org)

and (3) the impact of untreated maternal prenatal depression on the well-being of offspring. (psychiatrictimes.com)
Maternal distress was measured 6 months postpartum by 9 items covering anxiety, depression and stress. (nih.gov)
Maybe it's because green spaces lessen depression, boosting maternal health. (thebump.com)
001), after adjusting for maternal depression and breastfeeding. (columbia.edu)

The first trimester was the most susceptible exposure window. (biomedcentral.com)
The late SSRI exposure group consisted of women with an SSRI order after the first trimester (n=2,596). (providence.org)
The early-only SSRI exposure group consisted of women with SSRI orders only in the first trimester (n=691). (providence.org)

Here, we use published data on the relationship between DDT spraying and levels in maternal serum and breast milk in Africa to estimate the increased exposure from spraying. (cdc.gov)

We compared results from (1) confounder-adjusted multivariable analyses, (2) a Mendelian randomization (MR) analysis using maternal rs1051730 genotype as an instrument for smoking quantity and ease of quitting, and (3) a negative control analysis comparing maternal and mother's partner's smoking associations. (plos.org)
In sensitivity analyses, we examined interactions between exposure and race. (researcher-app.com)

Anatomy21

Diseases66

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment75

Psychiatry and Psychology13

Phenomena and Processes55

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena11

Technology, Industry, Agriculture1

Information Science10

Named Groups19

Health Care60

Geographicals10

Pregnancy66

Outcomes24

Infant21

Perinatal11

Cohort7

Fetal exposure3

Abstract3

Fine particulate matter2

Births7

METHODS4

Obesity10

Birthweight7

10th percentile2

Impact of maternal1

Childhood16

Conclusions2

Infants10

Objective2

Adverse2

Examine1

Race-ethnicity2

Premature Birth1

Concentrations8

Newborn1

Risk26

Findings3

Metrics1

Small4

Phthalate3

Median2

Genetics1

Characteristics1

Glucose2

Intrauterine3

Adjustment for maternal3

Independent of maternal1

Outcome1

Statistically1

Active maternal1

Fetus2

Logistic regression3

Improve maternal1

Study9

Baby's1

Depression4

Trimester3

Serum1

Analyses2