Experiments biological transport. Medical search. Frequent questions

Transport phenomena in cellular biological media (biofilms, tissues, etc. (aiche.org)
Materials science investigations covered such fields as biotechnology, electronic materials, fluid dynamics and transport phenomena, glass and ceramics, metals and alloys, and acceleration measurements. (wikipedia.org)
The rotating diffusion cell (RDC) was a relatively new method for characterizing transport phenomena which has been used in model skin penetration studies. (cdc.gov)
But applications beyond the capability of classical force-field methods include such fundamental processes as electronic transitions (photon absorption, non-linear spectroscopy), electron transport phenomena and proton transfer. (cecam.org)
Experiments on model systems and molecular simulations can make an important contribution to understanding a variety of phenomena involving biological membranes. (ens-lyon.fr)
Microscale heat and mass transport phenomena in biological systems. (bio.net)

The use of simple organic liquids as models for biological membranes has been suggested since the turn of this century. (cdc.gov)
Ionomycin is a calcium ionophore commonly derived from produced by the bacterium Streptomyces conglobatus, which means that it helps to transport calcium ions across cell membranes. (sigmaaldrich.com)
Biological membranes compartmentalize cells and regulate molecular transport and the activity of membrane proteins. (ens-lyon.fr)
From the biology standpoint, cell membranes are amazingly complex: they contain a huge variety of lipids and proteins, all contributing to biological functions. (ens-lyon.fr)
To understand the functioning of biological membranes in vivo is a great challenge, hence simplified model systems are often used to gain insight into specific structures and processes. (ens-lyon.fr)
This symposium aims at exploring how simulations and experiments on model systems can be used to understand the structure, dynamics, and functioning of real biological membranes. (ens-lyon.fr)
This allowed us to observe the structure and dynamics of the cobalamin transport complex (BtuB-TonB), β-barrel assembly machinery (BAM) and the outer membrane lipopolysaccharide translocon LptDE in intact E. coli and isolated native membranes. (fu-berlin.de)

In this project, studies are conducted to investigate the fundamental processes--including diffusive and convective transport, sorption/desorption, and biodegradation--that affect the fate and transport of both the liquid and vapor phases of volatile organic compounds (VOCs) in soil and geologic sediments. (nih.gov)
Research focuses on the coupled and interdependent physical, chemical, and biological processes determining the transport and distribution of chemical mixtures. (nih.gov)
Relationships between VOC transport processes and field-scale geological attributes of the vadose zone are being determined. (nih.gov)
It is a powerful tool for studying calcium signaling and its role in various biological processes, including cell activation, secretion, proliferation, and apoptosis. (sigmaaldrich.com)
Here, we show that transient thermal transport reflects macromolecular energy landscape architecture through both (i) the topological characteristics of the conformational ensemble and (ii) the nonlinear processes that mediate dynamics. (nist.gov)
Unlike transport through small molecule systems, such as alkanes, nonlinearity dominates over coherent processes at even quite short time- and length-scales. (nist.gov)
It clearly and concisely provides extensive details about the animal models, both past and present, that have been used to investigate a selected number of disease processes caused by exposure to plausible biological threat agents. (cdc.gov)
But many fundamental biological processes that involve, for example, the conversion of light into energy forms that are usable for chemical transformations are quantum mechanical in their nature. (cecam.org)
To fully understand the interplay between the physical cues from the microenvironment and biological processes requires that we resolve and define physical properties of cells, tissues on multiple length scales (sub-microns to millimeters), and temporal scales (milliseconds to days). (nih.gov)
SESSIONS * Heat and mass transport in tissue engineering processes. (bio.net)
Through its molecular chaperone activity, HSP27 regulates numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. (thermofisher.com)

We also work on more general problems such as those associated with conducting organics, quantum phase transitions in random systems and single molecule electron transport. (edu.au)
Based on this observation, the work presented in this thesis addresses novel possibilities to introduce both chemical and physical sensitivity in fluorescence spectroscopy and imaging studies relying on fluorescent probes compatible with both biological environments and single-molecule based super-resolution microscopy. (unige.ch)

1989. Evaluate and characterize mechanisms controlling transport, fate and effects of army smokes in the aerosol wind tunnel. (cdc.gov)
We are interested in two areas of research - 1) mechanisms of lipid modification of proteins and 2) transition metal transport and homeostasis. (nih.gov)
Alterations in hepatic disposition of CDF have been attributed traditionally to changes in biliary excretion, ignoring other relevant transport mechanisms, namely, uptake and basolateral efflux, where important interactions are likely to occur. (aspetjournals.org)
Our appreciation of almost all aspects of biochemistry and molecular biology has been enhanced by the elucidation of atomic resolution structures that reveal the underlying chemical mechanisms responsible for biological function. (york.ac.uk)

Recent technological breakthroughs, such as ultra-fast pulsed lasers, high-performance computing and crystallography of macromolecules, helped to improve the experimental tools of physicists, biologists, and chemists working, in particular, in the area of chemical and biological physics. (cecam.org)
Often atomic-level details are known from experiments in chemical and biological physics these days. (cecam.org)
For example, in biological physics these details are mainly obtained by x-ray crystallography of a crystallized version of the macromolecules. (cecam.org)
We operate at the boundary between physics, chemistry and biology, and address key questions in specific systems such as organic superconductors and biological macromolecules. (edu.au)

First, MT is a redox-active zinc protein, in which biological oxidants react with the thiolate ligands of its clusters and mobilize zinc. (nih.gov)
p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc. (uniprot.org)
p>This section provides any useful information about the protein, mostly biological knowledge. (uniprot.org)
The role of different lipid and protein species in the biological context is often far from clear. (ens-lyon.fr)
Sikora A, Joseph B, Matson M, Staley JR, Cafiso DS ( 2016 ) Allosteric Signaling Is Bidirectional in an Outer-Membrane Transport Protein. (fu-berlin.de)
appreciate how protein structure relates to protein mechanism and thus to biological function. (york.ac.uk)

We use a combination of cryoEM, crystallography, in vitro biochemistry and biophysics in combination with cell biological experiments. (nih.gov)

This membrane system was shown to contain both hydrated proteinaceous and lipoidal phases known to be present in stratum corneum, and was deemed potentially promising for skin transport studies. (cdc.gov)
A different approach was the use of a membrane composed of synthetic zeolites incorporated into a polystyrene matrix, but their future for skin transport studies did not appear promising. (cdc.gov)
Open questions remain in the area of membrane remodeling, molecular transport, the role of membrane lateral heterogeneity, and many others. (ens-lyon.fr)
To address fundamental questions of membrane transport, Dr. Bezrukov's section combines physical theory with experiments on bacterial, mitochondrial, and toxin-induced membrane channels, reconstituted in planar lipid bilayers. (nih.gov)
The function of cells depends on transport of diverse molecules across the biological membrane. (fu-berlin.de)
learn about the wide range of functions which can be performed by proteins, such as enzymes, signalling proteins, membrane bound transport proteins and structural proteins. (york.ac.uk)

Development of new theoretical models for interstitial flow and diffusion in cellular biological media (tissues, biofilms, etc) through a consistent combination of the spatial averaging method for the derivation of upscaled equations, with the particle-in-cell method for the calculation of macroscale parameters as functions of microscale system properties. (aiche.org)
A multiscale theoretical model for fluid flow in cellular biological media, International Journal of Engineering Science 51:241-271 (2012). (aiche.org)
The experiments proposed in this application will investigate the roles of metallothionein (MT) and its apoprotein thionein (T) in this process and the role of the MT/T ratio as a regulated zinc donor/acceptor pair that controls the availability of cellular zinc, directs cellular zinc fluxes to and from cellular compartments, and controls zinc-dependent cellular events. (nih.gov)
The experiments are of fundamental importance for an understanding of the role of zinc in cellular metabolism, gene expression, and signal transduction, and in the future will aid in devising new diagnostic, prognostic, and therapeutic means to address zinc-related disorders. (nih.gov)
This network of small tubes within a cell provides structural support and acts as a kind of inner cellular railway system, transporting organelles and molecular complexes vital for a cell's survival. (nih.gov)
Biological output by VEGF is mediated through distinct receptor/co-receptor complexes and generates signals in all cellular compartments triggering cellular responses such as cell migration, cell proliferation, vessel formation and maturation, as well as changes in vessel fenestration, constriction and permeability. (smw.ch)

explore the engineering of proteins using various techniques - including rational amino acid mutagenesis, random mutagenesis and DNA shuffling experiments and computer aided design. (york.ac.uk)

Most calculations on large chemical and/or biological molecules use classical molecular dynamics up to now. (cecam.org)
Examples include charge transport in single DNA molecules, and coherence in photosynthetic arrays. (edu.au)
When the molecules move along a concentration gradient, the chemical potential energy itself could drive the transport. (fu-berlin.de)

With a lethal dose to humans of less than 1 mcg, botulinum toxins are the most poisonous substances known and pose a great threat as an agent of biological warfare . (medscape.com)
Potentially lethal biological agents were unleashed on an unsuspecting British public and chemical warfare was trialed on military personnel as part of Ministry of Defense (MOD) experiments carried out over decades, a shocking new book reveals. (rt.com)
In his latest work, entitled ' Secret Science: A Century of Poison Warfare and Human Experiments, ' University of Kent historian Ulf Schmidt presents a series of case studies about covert state projects conducted between 1939 and 1989. (rt.com)

The experiments are based on recent discoveries of new biological activities of these proteins. (nih.gov)

A battery of in vivo and in vitro measurements was made: pulmonary mechanics in vivo, reactivity to inhaled MCh aerosol in vivo, in vitro reactivity of airway smooth muscle to MCh, smooth muscle responses to motor nerve stimulation in vitro, ion transport by airway epithelium in vitro, and vascular permeability of lung blood vessels. (cdc.gov)
Our data illustrates conformational transitions of Slc26a9, supporting a rapid alternate-access mechanism which mediates uncoupled chloride transport with negligible bicarbonate or sulfate permeability. (nih.gov)

In the method, Monte Carlo simulation for light transport in tissues is used to specify a relation among the RGB-values and chromophore concentrations and the wavelength-dependences of scattering spectra for biological tissues. (optica.org)
Experiments with small animals demonstrated the ability of the method to evaluate physiology and viability of in vivo living tissues. (optica.org)

While the former determines transport pathways via molecular contacts, the latter reflects the ruggedness of the landscape for local motion of atoms and molecular fragments. (nist.gov)
Ligand-induced receptor is internalised and then transported through early, late, and recycling endosomes, and finally degraded by proteasomal or lysosomal pathways. (smw.ch)

Today, doses of refrigerated stallion semen are stored, sent, and transported in single-use polystyrene transport boxes. (researchgate.net)

General structure, classification and biological importance (Role of Bacteria in Rhizosphere, Nodulation). (universitypk.com)

Here we review recent experiments showing how VEGFR-2 is transported through intracellular vesicular compartments specified by Rab family GTPases, and discuss how different VEGF-A isoforms specify intracellular receptor trafficking. (smw.ch)

Fluorescence microscopy and spectroscopy are in-vivo compatible techniques that are currently standard tools to address questions related to the organization and the dynamics of biological systems. (unige.ch)

Even first experiments on laser control in biological light-harvesting complexes have been performed [9]. (cecam.org)

The student will also work closely with their NCI mentors to perform imaging experiments for longitudinal cancer studies as well as the subsequent analysis. (nih.gov)

The main objective of the internship is therefore to complete the existing full-field OCT microscopy set-up to allow polarimetric contrast measurements on biological samples provided by medical partners. (fresnel.fr)
Ketter S, Joseph B ( 2023 ) Gd(III) - trityl - nitroxide triple labelling and distance measurements in the heterooligomeric cobalamin transport complex in the native lipid bilayers. (fu-berlin.de)

Discoveries often emerge from a creative interplay among theory, experiment, computer-based modeling and simulation, and the development of new instruments. (nsf.gov)

Quantum coherences and their effects on spectroscopy of large molecular aggregates are a very exciting issue these days due to recent experimental progress on both biological and synthetic samples showing unexpected long coherence times in large disordered systems. (cecam.org)

ISAIAH was the first microgravity experiment flown for the Israel Space Agency (ISA). (wikipedia.org)
Originating from Tel-Aviv University, it was intended to observe the effects of microgravity on oriental hornets and their ability to build combs in zero-g.: 28 However, a failure in the water system resulted in an unexpected rise of the humidity level in the experiment, which resulted in the deaths of 202 out of the 230 hornets and 103 pupae out of the 120 in the experiment. (wikipedia.org)

tissue and organ cryopreservation * Mass transport limited function in the design and operation of artificial organs. (bio.net)
In biological research, the cryopreservation of mammalian cells is an invaluable tool. (cls.shop)

Our exhaustive all-atom simulations and novel local-in-time and space analysis, applicable to both theory and experiment, permit dissection of energy migration in biomolecules. (nist.gov)

Development of a novel computer simulator of biofilm growth dynamics in porous media, which combined a continuum-based approach for fluid flow and mass transport with individual-based approaches for biofilm growth and detachment. (aiche.org)
The approach demonstrates that vibrational energy transport can probe otherwise inaccessible aspects of macromolecular dynamics and interactions that underly biological function. (nist.gov)
She has served on the steering team for field studies in urban air dispersion (DHS/DTRA NYC Urban Dispersion Program) and archipelago oceanography (ONR Philippines Straits Dynamics Experiment). (bnl.gov)

The letters transported with these rockets received special stamps which are nowadays greatly coveted by philatelists. (wikipedia.org)

Another great challenge is to establish a bridge between simulated systems and the ones used in experiments, to allow interpretation of experiments via simulations. (ens-lyon.fr)

This reference will equip researchers with pertinent information regarding current animal models, so that future work will not repeat experiments already performed, while at the same time minimizing the number of animals projected for future biodefense studies. (cdc.gov)
Government researchers were experimenting with the rabbit haemorrhagic disease virus ( RHDV ) on Wardang Island, off South Australia's coast, when renegade flies picked up the pathogen and transported it to the mainland. (thecut.com)

This workshop aims on bringing those people together who work on biological and/or synthetic systems to discuss and exchange ideas how to most efficiently and accurately solve the above mentioned problems. (cecam.org)
An important application in the described field of research are biological as well as artificial light-harvesting systems and solar cells. (cecam.org)
The key role that hepatobiliary transport systems play in the uptake and excretion of many xenobiotics and metabolites into and out of hepatocytes has been recognized only recently. (aspetjournals.org)
Blood vessel systems and leaf venations are typical biological transport networks. (duke.edu)

The characterization of structure-guided mutants illuminates the properties of the ion transport path, including a selective anion binding site located in the center of a mobile module within the transmembrane domain. (nih.gov)
Uptake of CDF in sandwich-cultured rat hepatocytes was impaired significantly by bromosulfophthalein, a substrate for organic anion-transporting polypeptides (Oatps), but was not modulated by specific Oatp2 or organic anion transporter (Oat) substrates. (aspetjournals.org)
CDF is not subject to hepatic metabolism and has been used as a substrate for organic anion transport. (aspetjournals.org)

1991. Documentation of the Threshold Limit Values and Biological Exposure Indices. (cdc.gov)
1993. Threshold limit values for chemical substances and physical agents and biological exposure indices for 1992 to 1993. (cdc.gov)
In one 1953 experiment, 20 year-old Royal Air Force (RAF) engineer Ronald Maddison was killed by exposure to what is now known as sarin gas. (rt.com)

The United States studied botulinum toxin as a military bioweapon until President Nixon signed the Biological and Toxin Weapons Convention in 1972, ending all US biotoxin weapons research. (medscape.com)
In a series of experiments, the research team led by Wei Li, Ph.D., a senior investigator in the NEI Retinal Neurophysiology Section and Jingxing Ou, Ph.D., a postdoctoral scientist in Li's lab, compared cells from non-hibernators to cells from the ground squirrel to determine differences in their response to cold. (nih.gov)
Our heroes find themselves stranded on a remote Pacific island which is home to the Division 9 facility: a secret biological research lab whose experiments with Element 115 and its effects on human, animal, and plant biology has created horrors beyond belief. (playstationlifestyle.net)
Biodefense: Research Methodology and Animal Models, edited by James R. Swearengen, is a timely and invaluable reference for those performing animal experimentation to develop medical countermeasures and diagnostics against infectious agents and toxins identified as potential biological weapons. (cdc.gov)
NASA Flight Engineers Shannon Walker and Michael Hopkins began Tuesday offloading the Dragon-transported critical research samples and stowing them in science freezers to be examined later. (nasa.gov)
A new human stem cell experiment, Space Organogenesis , got underway today after JAXA astronaut Soichi Noguchi collected biological samples and research hardware from Dragon. (nasa.gov)
This line of research serves as the basis for the development of new approaches to treatment of many diseases where regulation of transport through ion channels plays the key role. (nih.gov)
The secretive biological and chemical research facility is located just 13 km from where on 4th March former Russian spy Sergei Skripal and his daughter Yulia were found slumped on a bench following an alleged Novichok nerve agent poisoning. (21stcenturywire.com)
IMAGE: Entrance to Porton Down chemical and biological research facility near Salisbury. (21stcenturywire.com)
The main objective of the Symposium is to bring together scientists and engineers from around the world involved in bioheat and mass transfer research and to provide a relaxed atmosphere for in-depth discussion and exchange of the state-of-the-art of related theory, experiments, and applications. (bio.net)

The multiple roles of zinc require spatiotemporal regulation of its uptake, transport, and distribution. (nih.gov)

Several recent reports demonstrate that biological samples can be transported by unmanned aerial vehicles (commonly referred to as drones) without affecting the laboratory results from the same samples. (medscape.com)
Ionomycin is commonly used in cell biology experiments to induce a rapid and controlled increase in intracellular calcium levels. (sigmaaldrich.com)

Responses were recorded in in vitro experiments via electronic data acquisition from apparatus used to measure responses in isolated, perfused trachea, electric field stimulation, and ion transport experiments. (cdc.gov)

Thermal performance to maintain the temperature between + 2°C and + 15°C for 48 hours, cooling kinetics during the first hour of storage, and biological parameters relating to motility, velocity and sperm viability were analyzed and compared to a control box. (researchgate.net)
No significant difference between the two boxes was observed on all thermal and biological parameters. (researchgate.net)
The ECOOL Box thus shows its thermal and biological efficiency and allows the transport of equine doses in a safe and eco-responsible way. (researchgate.net)

This symposium is a follow up of the highly successful First Symposium on Bioheat and Mass Transport held in 1991. (bio.net)

Although CDF is eliminated from hepatocytes primarily via biliary excretion and, hence, appears to be a promising probe to study biliary excretion of organic anions, the hepatic transport of CDF has not been characterized fully. (aspetjournals.org)

We addressed the stability of biological samples in prolonged drone flights by obtaining paired chemistry and hematology samples from 21 adult volunteers in a single phlebotomy event-84 samples total. (medscape.com)
This remarkable feature is typical for biological metal metabolism as contrasted to pure inorganic chemistry. (nih.gov)
This first half of this module covers Gene Regulation and Genetic Engineering with a strong Biological Chemistry perspective. (york.ac.uk)
This module builds on core biological chemistry material taught in Year 2 of the chemistry degree. (york.ac.uk)
The first half of the course (for Chemists only) provides a detailed overview of molecular biology - a field which over the last 50 years has transformed biological chemistry. (york.ac.uk)

A German physician, Dr. Justinus Kerner, published the first case descriptions of botulism in 1822, with experiments conducted on himself and laboratory animals. (medscape.com)
The Pentagon has spent at least $70 million on military experiments involving tests with deadly viruses and chemical agents at Porton Down - the UK military laboratory near the city of Salisbury. (21stcenturywire.com)

Life sciences included experiments on human health, cell separation and biology, developmental biology, animal and human physiology and behavior, space radiation, and biological rhythms. (wikipedia.org)
However, many compounds are substrates for more than one transport system, and this adds to the complexity of studying hepatobiliary transport in the whole cell and intact organ. (aspetjournals.org)

Sergey M. Bezrukov is a Senior Investigator and chief of the Section on Molecular Transport, Program in Physical Biology, NICHD/NIH, a position he has held since October 2002. (nih.gov)

Long drone flights of biological samples are feasible but require stringent environmental controls to ensure consistent results. (medscape.com)
Additionally, we performed array Comparative Genomic Hybridization (aCGH) experiments using the 14 water buffalos as test samples and Olimpia as the reference. (usda.gov)

Botulinum toxin is classified by the Centers for Disease Control and Prevention (CDC) as one of the six highest-risk threat agents for bioterrorism because of the high lethality, ease of production and transport, and need for prolonged intensive care treatment. (medscape.com)
The US Defense Threat Reduction Agency (DTRA) has also funded experiments on animals which were exposed to chemical agents such as Sulfur Mustard and Phosgene gas. (21stcenturywire.com)

In the second part, I will discuss our recent modeling work on the initiation process of transport networks. (duke.edu)

Biological effects of inhaled crude oil vapor. (cdc.gov)

Serial passage experiments were conducted using steadily increasing concentrations of LL-37, PR-39 or wheat germ histones. (nih.gov)

To provide molecular details of its transport mechanism, we present cryo-EM structures and a functional characterization of murine Slc26a9. (nih.gov)

The CNV regions overlap 1245 genes and are significantly enriched for specific biological functions such as immune response, oxygen transport, sensory system and signalling transduction. (usda.gov)
Most chapters are devoted to a specific biological agent or toxin and supply interesting historical information as well as descriptions about the pathogenesis in humans and in animal models. (cdc.gov)

The Japanese in World War II carried out human experiments on prisoners in Manchuria. (medscape.com)
Computer-based intelligence such as an upload could think much faster than a biological human even if it were no more intelligent. (wikipedia.org)

Briefly, the earlier reports of drone-transported biologics were performed in ambient temperatures that were around room temperature [ 1 ] or cold, [ 2 , 3 ] and the maximal length of flight in those studies was 40 minutes (equivalent of 40 km) in a fixed-wing vehicle and 27 minutes (equivalent of 13-20 km) in a multirotor. (medscape.com)
Time resolved spectroscopic experiments employing nitroxide labels and endogenous paramagnetic metal centers are employed in these studies. (fu-berlin.de)

Results will cover the ocean response to atmospheric flows around island topography (Philippines and Madeira), as well as sea breeze interactions with city morphology (New York and Tokyo) - and associated transport & dispersion applications. (bnl.gov)
Applications include predicting chemical, biological, radiological and nuclear (CBRN) dispersion in coastal cities in the event of a terrorist or accidental release. (bnl.gov)

Spacelab-J included 24 experiments in materials science and 20 life sciences experiments, the majority of which were sponsored by NASDA and NASA, while 2 were sponsored by collaborative civilian efforts. (wikipedia.org)
The Payload Crew Training Manager was Homer Hickam, who also worked during the mission as a Crew Interface Coordinator to talk to the crew during their science experiments and relay any concerns from the scientists on the ground. (wikipedia.org)
I am a physicist who strives to understand functioning of biological molecular structures from the first principles of physical science. (nih.gov)

Quantitative descriptions of these relationships are being incorporated into vadose zone transport models which include modeling experiments of flow and transport. (nih.gov)
The information in this chapter is well organized and completely outlines the topic, to include transporting and caring for aerosol-challenged animals. (cdc.gov)

Anatomy5

Organisms1

Chemicals and Drugs15

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Phenomena and Processes14

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science3

Phenomena6

Membranes7

Processes11

Single Molecule2

Mechanisms4

Physics4

Protein6

Biophysics1

Membrane6

Cellular6

Amino acid1

Molecules3

Warfare3

Proteins1

Permeability2

Tissues2

Pathways2

Polystyrene1

Bacteria1

Compartments1

Vivo1

Complexes1

Longitudinal1

Measurements2

Simulation1

Spectroscopy1

Microgravity2

Cryopreservation2

Theory and experiment1

Dynamics3

Nowadays1

Simulations1

Researchers2

Systems4

Anion3

Exposure3

Research10

Uptake1

Commonly2

Vitro1

Thermal3

19911

Organic1

Chemistry5

Laboratory2

Cell2

Biology1

Samples2

Threat2

Recent1

Vapor1

Concentrations1

Functional characterization1

Specific2

Human2

Studies2

Applications2

Science3

Include2