• Traditionally, the main set of evidence for the genetic proposal of Proto-Finno-Ugric has come from vocabulary. (wikipedia.org)
  • We found evidence of severe genetic bottlenecks, with the effective population size dropping 85-91% after eradication, consistent with declines in population sizes. (frontiersin.org)
  • The finding of a MYO7A mutation in two related Hutterite families from northern Alberta provides evidence of genetic heterogeneity in Hutterites affected by Usher syndrome type I. (molvis.org)
  • Here, we describe two Hutterite families from northern Alberta with Usher syndrome type I who did not carry a mutation in exon 10 of PCDH15 but did carry a mutation in exon 3 of the myosin VIIA ( MYO7 A) gene, providing evidence of genetic heterogeneity in Alberta Hutterites with Usher syndrome type I. (molvis.org)
  • One theory to explain the high frequency of FH in some populations is the founder effect, which is the loss of genetic variability in a population that occurs when a new population is formed through the migration of a small number of individuals who carry a higher proportion of FH mutations by chance. (acc.org)
  • When the population expands there would be a higher proportion of affected individuals who share the specific genetic variant introduced by the founders. (acc.org)
  • Castaman G, Bertoncello K, Bernardi M, Eikenboom JC, Budde U, Rodeghiero F: Autosomal recessive von Willebrand disease associated with compound heterozygosity for a novel nonsense mutation (2908 del C) and the missense mutation C2362F: definite evidence for the non-penetrance of the C2362F mutation. (karger.com)
  • As the Hutterite populations are genetically isolated, we hypothesized a founder effect, that the same mutation would be carried by all Hutterites. (molvis.org)
  • A novel splice donor mutation affecting position +3 in intron 6 of the factor VIII gene. (eahad.org)
  • In this article, we review and update current knowledge about the distribution and spatial spread of the disease, its observed impact on affected host populations, and models to predict its consequences for host population dynamics. (springer.com)
  • p.Q18X) in the myosin VIIA ( MYO7A ) gene was found in the homozygous state in the affected siblings. (molvis.org)
  • All affected persons had homozygous deletion of 12 bp (155-166del) in exon 3 of the TBCE gene. (who.int)
  • Neuroimaging and neurophysiological studies have shown that listening to and/or playing music has multiple effects on brain structure and function, suggesting a biological effect. (bmj.com)
  • Dr Alex Tournier, founder of HRI, discusses nano particles as a way of describing the mechanism of action, the biological effect of ultra dilutions in Homeopathy. (bvs.br)
  • That rulemaking process has been slow, so a new rule wouldn't come into effect until July 2023 at the earliest, and more likely not until the following year. (nakedcapitalism.com)
  • Going forward, the Founder mantra will be efficiency and scale, Coatue predicts. (egonzehnder.com)
  • Additionally, our experimental data indicates that multiple blood feeding events, which more closely mimic mosquito-feeding behavior in the wild, can hasten the course of infections, and our model predicts that this effect is sensitive to the amount of virus imbibed. (bvsalud.org)
  • However, the effects of dominant species and its derived dominance structure on the community stability remain poorly understood. (researchsquare.com)
  • This difference was mainly attributed to higher compensatory effect and selection effect of dominant species in the mesic meadows. (researchsquare.com)
  • Furthermore, dominant structure strongly affected community stability through increasing dominant species stability and species asynchrony. (researchsquare.com)
  • However, species richness had almost little effect. (researchsquare.com)
  • First, species diversity has been intensively found to keep communities stable through "portfolio effect" (Chen et al. (researchsquare.com)
  • 2020 ). Second, species interaction creates a "compensatory effect" among asynchronous species to balance between the increase and decrease of productivity in different species (Grman et al. (researchsquare.com)
  • Third, dominant species can beget a "selection effect" to stabilize communities due to its prominent contribution to the productivity of the overall communities (Donohue et al. (researchsquare.com)
  • 2020 ). Previous studies have examined extensively the importance of the richness effects and species asynchrony to community stability. (researchsquare.com)
  • However, the effects of dominant species and dominance are less understood. (researchsquare.com)
  • Dominant species may affect community stability in at least two pathways (Song et al. (researchsquare.com)
  • 2007 ). First, dominant species play a disproportionate effect than other species on the community stability through selection effect (Hillebrand et al. (researchsquare.com)
  • She is founder and co-director of the nonprofit Scrubs Addressing the Firearm Epidemic , or SAFE, which promotes research, education and evidence-based policy as a means to reduce firearm injuries. (stanford.edu)
  • Originally called the Boston Women's Health Book Collective, OBOS is a global nonprofit that promotes accurate, evidence-based information on girls' and women's reproductive health and sexuality, and addresses the social, economic, and political conditions that affect health care access and quality of care. (ourbodiesourselves.org)
  • While the number of preterm births in Brazil for 2020 has yet to be released, experts such as Denise Suguitani-founder and director of nonprofit Prematuridade, the only national NGO in the country to support premature babies and their families-suspect there will be an increase over previous years. (technologyreview.com)
  • Rolands Mesters, founder and managing director of Nordigen, discusses the beneficial effects that sharing data can have on our finances. (information-age.com)
  • The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described. (cdc.gov)
  • 17 The high prevalence in Lebanon is attributed to the founder effect from early settlements groups, as well as high rates of consanguinity. (acc.org)
  • Already, they point out, high profile Founders have pivoted away from pushing growth. (egonzehnder.com)
  • SINGAPORE - Iris Koh, the founder of anti-vaccine group Healing the Divide, was again denied bail on Monday (Jan 31) after her lawyer took to the High Court in a bid for her to be released before the Chinese New Year festivities. (todayonline.com)
  • The high prevalence of FH among people with CAD provides evidence supporting systematically screening those with CAD for FH, followed by cascade screening of family members of those diagnosed with FH. (cdc.gov)
  • The effects of high vs. low hepatic lipogenesis on lipid metabolism. (medscape.com)
  • But by that time the crisis had made it clear that some of the country's most vulnerable patients were being heavily affected by the pandemic, even if they didn't actually have covid-19. (technologyreview.com)
  • A 2020 report concluded that 2019's breaches in the health care sector affected an excess of 27 million people , and the total number of records exposed more than doubled compared to the previous year. (information-age.com)
  • The outlook by Coatue Management shows Founders face a "year of efficiency. (egonzehnder.com)
  • Using a relative weight analysis, they evidence that the money BA provide and the screening they undertake are by themselves the most important factor regarding venture survival, subsequent propensity to generate web traffic, and sales. (uni-bremen.de)
  • Given this new economic reality, it is important for Founders to build a culture of data driven decision making that prioritizes responsible, sustainable, and most importantly profitable growth. (egonzehnder.com)
  • The regulations might, or might not, have had a direct effect on the livelihood of tattoo artists, and it is important to investigate the direct effects of REACH on a major artistic industry in Europe. (lu.se)
  • I argue that this reply ultimately founders due to an important disanalogy between nudging cases and the case of action performed under causal determinism. (lu.se)
  • Meanwhile, these challenges affect and are affected by policies and actions in different sectors beyond health. (who.int)
  • Significant evidence of linkage was obtained on chromosome 4q22 (LOD 3.33) and suggestive evidence of linkage at 8q13-21 (LOD 2.29) with the combined music test scores, using variance component linkage analyses. (bmj.com)
  • What tends to be forgotten are the long-term effects these injuries have on the people who survive and the monetary costs to the health care system. (stanford.edu)
  • Ties for Lives raises awareness of youth mental health issues through its evidence based SPOTa program, which helps young people and their families Spot the early signs of depression and anxiety and assists people to get help. (greghunt.com.au)
  • Ties for Lives founder David L Wright said mental health issues affected a large number of young people in the community. (greghunt.com.au)
  • Often more people die from the health effects - such as cholera or lack of access to essential health services - than from the direct effect. (who.int)
  • The authors suggested that the inclusion of studies from more regions and the exclusion of those reporting founder effects may explain the difference in estimates. (cdc.gov)
  • He explains that there is evidence from scientific studies that prove the effectiveness of homeopathy. (bvs.br)
  • Auscultation of the chest showed normal heart sounds with a slight early systolic murmur, maximal at the upper left sternal border, attributed to a persistent ductus arteriosus as evidenced by cardiac ultrasonography. (bmj.com)
  • Where there was evidence of an early commitment to finance for many of these businesses, they frequently de-prioritized the function as they grew - for example, failing to replace a departing CFO or VP Finance. (egonzehnder.com)
  • However, the data does tend to support the advice we give to many of our Founder-led clients: invest early in finance, ensure that your hire is appropriate for the stage of your business and give that person a seat at the table in terms of setting strategy and building culture. (egonzehnder.com)
  • Many crucial methods of care for these babies, including early breastfeeding and skin-to-skin contact with their parents, remain on hold at hospitals around the country despite evidence that this puts their growth, development, and even survival at much higher risk than covid-19. (technologyreview.com)
  • 4. Fetal/early life exposures and long-term effects. (cdc.gov)
  • In early 2022 a ban came into effect in the European Union, and a few other key cooperative nations, prohibiting numerous chemicals used in tattoo ink and permanent make-up. (lu.se)
  • The most prevalent pathogenic MKRN3 variant p.Gly312Asp was exclusively found among the Cypriot CPP cohort, indicating a founder effect phenomenon. (frontiersin.org)
  • Recommendations for cholesterol screening in children differ: while the National Heart, Lung, and Blood Institute (NHLBI) guidelines recommend universal cholesterol screening for children at ages 9-11 and 18-21, the United States Preventive Services Task Force found insufficient evidence to recommend for or against cholesterol screening in children. (cdc.gov)
  • How could mistaken release of cellphone data affect Texas lawyer for Infowars founder Alex Jones? (abajournal.com)
  • Qualitative evidence from reconstructed vocabulary and correlations with archaeological data suggest that IndoEuropean languages originated in the Pontic-Caspian steppe and spread together with cultural innovations associated with pastoralism, beginning c. 6500-5500 bp. (blogspot.com)
  • It is a prime example of a data-driven approach that aims to accelerate current product development cycles, according to Nuritas' founder and CSO Dr Nora Khaldi, who has been at the helm of the Irish-based firm since 2014. (nutraingredients.com)
  • Data protection security laws affect how entities can handle health information, the length of time a party should store it and more. (information-age.com)
  • Although not as well researched as smoking, there is evidence that snus can cause both reversible and irreversible oral tissue damage and that consumption during pregnancy increases the risk of prematurity and intrauterine foetal mortality. (cancercentrum.se)
  • Life expectancy is not known to be affected. (medscape.com)
  • 2 This implies the existence of an innate ability, which later in life can be modified by environmental effects. (bmj.com)
  • Although there is, as yet, no published evidence that sirtuins extend life in mammals, or that resveratrol activates sirtuins in human cells, some of these molecules are already in clinical trials for safety. (supercentenarian.com)
  • The authors do not speculate about how this difference would affect the day-to-day life of participants who took the drug, although they do refer to "modestly less decline" of cognition/function in the lecanemab group. (medscape.com)
  • Monks who practiced Buddhist meditation had evidence of significantly greater brain activity, called gamma wave activity, in areas associated with learning and happiness compared with those who didn't practice meditation, according to a recent study. (webmd.com)
  • This study, known as CALERIE (Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy), was sponsored by America's National Institutes of Health. (supercentenarian.com)
  • With the study the author presents evidence that quantum-nano-domains offer greater explanati. (bvs.br)
  • Has the invasion of Ukraine affected your current analysis? (libdemvoice.org)
  • it matters very little what specific century they happen in, except as that affects the accuracy of the branching, which as I say, is defined in relative terms. (blogspot.com)
  • in this issue of the journal [ 4 ] have added to the evidence base that targeting patients with hypertriglyceridaemia with statins or other triglyceride-lowering therapies may significantly reduce CV events in patients without pre-existing atherosclerotic cardiovascular disease (ASCVD) and therefore represents a population that deserves special attention for the primary prevention of coronary heart disease. (medscape.com)
  • Consistent with business angel (BA) and venture capital research they find geographic and industry closeness, the existence of patents and prototypes as well as the authenticity and tonality of the entrepreneurial pitch to have a positive effect on founders getting a deal during the show. (uni-bremen.de)
  • Chagas disease is the most common parasitic infection in Latin America, annually affecting ≈5-6 million persons and putting another 70 million at risk ( 1 ). (cdc.gov)
  • They have also led to a search for drugs that mimic the effects of calorie restriction without the pain of going on an actual diet. (supercentenarian.com)
  • We're doing it through a personalized, evidence-based approach to care. (forbes.com)
  • One issue that affects the clinician's understanding of the role of triglycerides in assessing CV risk is the nomenclature. (medscape.com)
  • educational level, perceived socioeconomic status and occupational status affect cessation attempt success where more affluent individuals seem to have the upper hand (9-11). (cancercentrum.se)
  • Providing evidence based, effective cessation support is thus a crucial tobacco control effort (8). (cancercentrum.se)
  • To explore the impact of this feeding behavior further, we examined the effects of partial blood feeding on DENV dissemination rates and midgut basal lamina damage in Ae. (bvsalud.org)
  • 2018). Documentation of a New Zealand blue whale population based on multiple lines of evidence . (oregonstate.edu)
  • Additionally, financial institutions must abide by stringent compliance measures, particularly when verifying a customer's identity or checking for evidence of money laundering. (information-age.com)
  • The Director-General, as Administrator of the Foundation, will take all actions required under Swiss law to effect the dissolution, including, as necessary, representing the Foundation, overseeing the liquidation, and seeking all necessary approvals from the Swiss surveillance authorities. (who.int)
  • It may make adherents of the steppe hypothesis feel better, but it fails to offer compelling evidence for their preferred narrative. (blogspot.com)
  • The law is no longer in effect, but it's considered evidence of the intent of the founders. (nbcnews.com)