Evidence spinal diseases. Medical search. Frequent questions

ALS is a progressive, fatal neurodegenerative disease affecting nerve cells in the brain and spinal cord that causes loss of motor control. (medscape.com)
of nerves in the brain and spinal cord. (msdmanuals.com)
It is suggested that CD8 + T-lymphocytes remain in the brain and spinal cord as tissue resident cells, which may focally propagate neuroinflammation, when they re-encounter their cognate antigen. (frontiersin.org)
An MRI to examine your brain and spinal cord. (hartfordhealthcare.org)
A Spinal tap (or lumbar puncture) can assess the fluid circulating around your brain and spinal cord for elevated disease markers of MS or other conditions. (hartfordhealthcare.org)
No virus could be isolated from brain and spinal cord specimens of sick goats. (cdc.gov)

Recent advances in the treatment of spinal muscular atrophy (SMA) have dramatically altered prognosis. (dovepress.com)
Spinal muscular atrophy (SMA) is an autosomal recessive, inherited genetic disease characterized by degeneration of alpha motor neurons in the spinal cord. (dovepress.com)
Spinal muscular atrophy type II (SMA2), also called "intermediate" SMA, occurs slightly later than type I, between the ages of 6 and 18 months, and is characterized by the absence of acquisition of autonomous ambulation. (dovepress.com)
Kennedy's disease or spinal bulbar muscular atrophy is a rare, inherited and slowly progressive multisystem disease mostly manifesting with a motor neuron disease phenotype leading to disability. (kennedysdisease.org)
Kugelberg Welander spinal muscular atrophy (also known as Wohlfart-Kugelberg-Welander syndrome or mild SMA) is a milder form of SMA, with symptoms typically presenting after age 18 months. (medscape.com)
Hoffmann called the syndrome spinale muskelatrophie (spinal muscular atrophy). (medscape.com)
Updates in clinical data for FDA-approved disease-modifying therapies for spinal muscular atrophy. (cdc.gov)
Spinal Muscular Atrophy: Mutations, Testing, and Clinical Relevance. (cdc.gov)

For specific nontraumatic neurologic diseases that affect the spinal cord, see Multiple Sclerosis , Amyotrophic Lateral Sclerosis , and other articles listed in Differentials. (medscape.com)
Musk said some people with a cervical spinal cord injury or amyotrophic lateral sclerosis ( ALS ) may qualify for the human clinical trial. (ehlinelaw.com)
People with paralysis due to cervical spinal cord injury or amyotrophic lateral sclerosis may qualify for the first human trial. (ehlinelaw.com)
Examples of less frequent but non-syndromic diseases newly diagnosed included multiple sclerosis , malignancy, Parkinsons disease, sarcoidosis, amyotrophic lateral sclerosis. (lymetalk.net)
The slow progression, partial androgen insensitivity, electrophysiological evidence of sensory neuronopathy, and relatively spared central nervous system pathways help differentiate it from amyotrophic lateral sclerosis. (kennedysdisease.org)

Other disorders that may require ambulation testing include spinal stenosis, arachnoiditis, degenerative disc disease, osteoarthritis, severe soft tissue injury, or bony/fibrous ankylosis. (disability-benefits-help.org)
However, in the long-run, the surgery may be associated with adjacent segment disc disease, a complication in which the spinal segments above and below the fused portions develop abnormalities such as disc degeneration, instability, spinal stenosis or disc herniation. (surreybackandjointclinic.co.uk)
[13] Surgery may be beneficial for those with disc-related chronic pain and disability or spinal stenosis . (wikipedia.org)
Spinal stenosis is narrowing of the spinal column that causes pressure on the spinal cord, or narrowing of the openings (called neural foramina) where spinal nerves leave the spinal column. (medlineplus.gov)
Spinal stenosis usually occurs as a person ages, however, some patients are born with less space for their spinal cord. (medlineplus.gov)
Most people with spinal stenosis cannot walk for a long period without having significant pain. (medlineplus.gov)
Spinal stenosis symptoms often become worse over time, but this may happen slowly. (medlineplus.gov)

This review focuses on the clinical description of common patterns of spinal cord involvement. (medscape.com)
Considerable differences exist in terms of clinical complications after traumatic and nontraumatic spinal cord injury (SCI). (medscape.com)
Clinical phenotypes are grouped into five forms depending on the severity of the disease and the age of onset. (dovepress.com)
The EPCs review all relevant scientific literature on clinical, behavioral, and organization and financing topics to produce evidence reports and technology assessments. (webharvest.gov)
The EPCs develop evidence reports and technology assessments on topics relevant to clinical, social science/behavioral, economic, and other health care organization and delivery issues-specifically those that are common, expensive, and/or significant for the Medicare and Medicaid populations. (webharvest.gov)
With this program, AHRQ became a "science partner" with private and public organizations in their efforts to improve the quality, effectiveness, and appropriateness of clinical care by facilitating the translation of evidence-based research findings into clinical practice. (webharvest.gov)
The EPCs develop evidence reports and technology assessments based on rigorous, comprehensive syntheses and analyses of the scientific literature on topics relevant to clinical, social science/behavioral, economic, and other health care organization and delivery issues. (webharvest.gov)
As in March, today we have to have an internal dialogue between our scientific scrutiny and clinical compassion," said Liana G. Apostolova, MD, Distinguished Professor in Neurology and the Barbara and Peer Baekgaard Chair in Alzheimer's Disease Research at the Indiana University School of Medicine, who originally voted against the application. (medscape.com)
This lack of supportive evidence suggests the subluxation construct has no valid clinical applicability . (sciencebasedmedicine.org)
Last Autumn a systematic review of the evidence was published in Focus on Alternative and Complementary Therapies entitled "Chiropractic for the prevention and/or treatment of sports injuries: a systematic review of controlled clinical trials. (quackometer.net)
This clinical quandary discusses oligoprogressive disease in metastatic melanoma and how treatment with immunotherapy and targeted therapy affect the disease. (cancernetwork.com)
At the time of this article, few clinical studies of spinal decompression therapy have been published in peer-reviewed medical journals. (spine-health.com)
In general the disease starts in patients in the third decade of life with a relapsing and remitting clinical course. (frontiersin.org)
2 )]. It is currently an open debate, whether primary progressive MS is a distinct disease entity or whether it just represents part of the variable clinical disease spectrum ( 3 - 5 ). (frontiersin.org)
In this case PPMS would be just a clinical variant of a common disease process. (frontiersin.org)
Although a physical exam and clinical laboratory tests showed few objective abnormalities, standardized symptom questionnaires revealed that patients with post-treatment Lyme Disease symptoms are highly and clinically significantly symptomatic, with poor health-related quality of life. (lymetalk.net)
1) Monoclonal antibodies directed against amyloid that are approved by FDA for the treatment of AD based upon evidence of efficacy from a change in a surrogate endpoint (e.g., amyloid reduction) considered as reasonably likely to predict clinical benefit may be covered in a randomized controlled trial conducted under an investigational new drug (IND) application. (cms.gov)
2) Monoclonal antibodies directed against amyloid that are approved by FDA for the treatment of AD based upon evidence of efficacy from a direct measure of clinical benefit may be covered in CMS approved prospective comparative studies. (cms.gov)
About Spondyloarthritis Spondyloarthritis refers to a family of chronic, inflammatory diseases that share common clinical features, including inflammation of the joints and the entheses (sites where ligaments and tendons attach to bones). (jnj.com)
Tator CH, Fehlings MG. Review of clinical trials of neuroprotection in acute spinal cord injury. (medscape.com)
If it is anticipated a patient will remain unconscious, unassessable or unreliable for clinical examination for morethan 48 hours, radiological spinal clearance imaging should be undertaken. (boa.ac.uk)
Sometimes, clinical evidence of degeneration may not accompany radiographic changes. (surreybackandjointclinic.co.uk)
This paper describes the clinical manifestations, diagnosis and management of schistosomiasis of the spinal cord in 5 patients attending Shaab and Ibn Khuldoun Hospitals, Khartoum from 1997 to 2007. (who.int)

Aug. 31, 2022 - Researchers in Sweden used a large population sample from a national registry to analyze changes in sick leave and disability pension in patients from 2006-2017, before and after they were implanted with spinal cord stimulation for chronic pain, compared to a reference group. (neuromodulation.com)
Some evidence showed that CBD reduced chronic pain, but the treatment effect was modest (an average improvement of about 0.4 on a scale ranging from 0 to 10). (nice.org.uk)
Unlike obstructive lung diseases, such as asthma and chronic obstructive pulmonary disease (COPD), which show a normal or increased total lung capacity (TLC), restrictive disease are associated with a decreased TLC. (medscape.com)
Multiple sclerosis is a chronic inflammatory disease of the central nervous system which leads to the formation of focal confluent lesions of primary demyelination in the white and gray matter and to diffuse damage and neurodegeneration in the entire brain ( 1 ). (frontiersin.org)
Whether from injury, joint problems, disease, or aging, your dog may have to deal with acute or chronic pain. (seniorpetproducts.com)
If approved, SIMPONI will become available for the treatment of patients with severe active nr-AxSpA, a form of spondyloarthritis-chronic inflammatory diseases affecting the spine-in which the predominant symptom is back pain and stiffness. (jnj.com)
About SIMPONI ® (golimumab) SIMPONI is a human monoclonal antibody that targets and neutralises excess tumor necrosis factor (TNF)-alpha, a protein that when overproduced in the body due to chronic inflammatory diseases can cause inflammation and damage to bones, cartilage and tissue. (jnj.com)
Chronic spinal cord injury. (medscape.com)
A prospective assessment of mortality in chronic spinal cord injury. (medscape.com)
We describe 4 patients evaluated at our Metabolic Bone Disease Clinic from May 1, 1997, to July 1, 2006, whose bone disorders resulted from chronic fluoride exposure due to excessive tea intake. (fluoridealert.org)
The CDC Surveillance Coordination Group has established a steering committee that is charged with the development of a broad range of case definitions for noninfectious conditions (e.g., environmental or occupational conditions, chronic diseases, adverse reproductive health events, and injuries). (cdc.gov)
To update our knowledge of chronic constipation and its etiology and best-evidence treatment, information was synthesized from articles published in PubMed, EMBASE, and Cochrane Database of Systematic Reviews. (medscape.com)
Chronic constipation should be managed according to its etiology and guided by the best evidence-based treatment. (medscape.com)

Neuromyelitis Optica (NMO) spectrum disorders are central nervous system disorders that can affect the spinal cord or vision. (hartfordhealthcare.org)

Powell also underwent an MRI in November 2007 that revealed multilevel cervical disc herniation with evidence of moderate cord compression. (justia.com)
The spinal cord comprises three parts: the cervical (neck), thoracic (chest), and lumbar (lower back) regions. (medicalnewstoday.com)
Most people have seven spinal bones in the cervical column, 12 in the thoracic column, and five in the lumbar column. (medicalnewstoday.com)

Equally as difficult is the determination of spinal degeneration. (cdc.gov)
Adjacent segment disc disease is associated with new degeneration symptoms, but may be asymptomatic and identified only during a follow-up imaging test. (surreybackandjointclinic.co.uk)
Myelopathyis injury to the spinal cord which can be due to inflammation, compression, or disc degeneration. (hartfordhealthcare.org)
Spinal muscular atrophies (SMAs) represent a rare group of inherited disorders that cause progressive degeneration of the anterior horn cells of the spinal cord. (medscape.com)

Sugarman B. Medical complications of spinal cord injury. (medscape.com)
Comparison of medical complications following nontraumatic and traumatic spinal cord injury. (medscape.com)
Spinal immobilisation is associated with pressure sores and pulmonary complications and is not recommended for more than 48 hours. (boa.ac.uk)

The committee noted that although use of cannabis-based medicinal products for intractable chemotherapy-induced nausea and vomiting would be short term, there was a lack of evidence on longer term adverse events, such as dependence and the development of psychological disorders. (nice.org.uk)
article, 98% of chiropractors believed that "most" or "many" diseases were caused by spinal misalignments and over 75% of chiropractors believed that subluxation was a significant contributing factor to 50% or more of visceral disorders (such as asthma and colic), an implausible idea that is not supported by any evidence whatsoever. (sciencebasedmedicine.org)
If caused by parenchymal lung disease, restrictive lung disorders are accompanied by reduced gas transfer, which may be marked clinically by desaturation after exercise. (medscape.com)
The second is extrinsic disorders or extrapulmonary diseases. (medscape.com)
Diseases of these structures result in lung restriction, impaired ventilatory function, and respiratory failure (eg, nonmuscular diseases of the chest wall, neuromuscular disorders). (medscape.com)
In cases of intrinsic lung disease, the physiological effects of diffuse parenchymal disorders reduce all lung volumes by the excessive elastic recoil of the lungs, relative to the outward recoil forces of the chest wall. (medscape.com)
The recent studies inconsistently have discussed about the influence of spinal disorders on total hip arthroplasty (THA). (ac.ir)
Methods: We searched on databases and evaluated the articles about spinopelvic parameters in patients with spinal disorders who needed THA. (ac.ir)

He also opined that Powell was unable to use her hands and fingers for more than one-third of each day due to nerve problems stemming from her spinal injuries. (justia.com)
It's healing implications to treat conditions like spinal injuries and treating conditions like obesity, autism, depression, and schizophrenia could change the world overnight. (ehlinelaw.com)
What evidence is there that chiropractic manipulation can either prevent or treat sports injuries? (quackometer.net)
It also provides some information about spinal cord injuries. (medicalnewstoday.com)

The gray matter is the dark, butterfly shaped region of the spinal cord made up of nerve cell bodies. (medicalnewstoday.com)
The white matter surrounds the gray matter in the spinal cord and contains cells coated in myelin, which makes nerve transmission occur more quickly. (medicalnewstoday.com)
The posterior root is the part of the nerve that branches off the back of the spinal column. (medicalnewstoday.com)
The spinal ganglion is a cluster of nerve bodies that contain sensory neurons. (medicalnewstoday.com)
The posterior and anterior roots come together to create a spinal nerve. (medicalnewstoday.com)
Spinal metastases may result in focal findings at a spinal cord level or nerve root pain. (medscape.com)

Spinal cord disease can result from diverse pathologic processes including trauma . (medscape.com)
Trauma to the spinal cord typically leads to a combination of symptoms and signs resulting from immediate and delayed injury. (medscape.com)
Additionally, recent evidence has shown that a wave of apoptosis further affects the oligodendrocytes up to 4 segments from the trauma site days and weeks after the initial trauma. (medscape.com)
Three major routes of spread are: (1) hematogenous spread from a distant infection, (2) direct inoculation from trauma, (3) direct inoculation following invasive spinal diagnostic procedures and from spinal surgery. (wheelessonline.com)
Still, Neural Link will revolutionize the way we treat diseases like Parkinson's disease, epilepsy, and in particular, spinal cord trauma. (ehlinelaw.com)
The role of trauma in low back diseases is reviewed. (cdc.gov)

There is evidence that chiropractic care, including spinal manipulation, improves migraine and cervicogenic headaches. (greenmedinfo.com)
They ask whether the evidence shows that chiropractic subluxations cause interference with the nervous system and whether they cause disease. (sciencebasedmedicine.org)
There is a significant lack of evidence in the literature to fulfill Hill's criteria of causation as regards chiropractic subluxation. (sciencebasedmedicine.org)
No supportive evidence is found for the chiropractic subluxation being associated with any disease process or of creating suboptimal health conditions requiring intervention. (sciencebasedmedicine.org)
The New Zealand Chiropractors' Association is celebrating World Spine Day (October 16th 2023) by pointing to the burgeoning evidence for chiropractic as the drug free means of managing spinal pain. (voxy.co.nz)
The chiropractic trade has a big problem with evidence. (quackometer.net)
ABSTRACT Background: Chiropractic is based on a theory that most disease results from spinal subluxation and interference with nerves. (skepdoc.info)
[18] The evidence for chiropractic care [19] and spinal manipulation is mixed. (wikipedia.org)

In the majority of patients multiple sclerosis starts with a relapsing remitting course (RRMS), which may at later times transform into secondary progressive disease (SPMS). (frontiersin.org)
Multiple Sclerosis , one of the most common neurological diseases, affects up to 1 million people in the United States. (hartfordhealthcare.org)

Children's spinal cords may stop slightly lower, at the second or third lumbar vertebrae. (medicalnewstoday.com)

Today, in well-organized spinal cord centers, 94% of patients survive the initial hospitalization. (medscape.com)
Type III (SMA3) or Kugelberg-Welander disease causes symptoms after the age of 18 months, and these patients acquire autonomous ambulation. (dovepress.com)
But whatever the true reasons for the delays in Musk's Neuralink, its first human applications would probably help spinal cord injury patients based on the research so far. (ehlinelaw.com)
In a minority of patients the relapsing remitting disease is skipped and the patients show progression from the onset (primary progressive MS, PPMS). (frontiersin.org)
About 15 percent of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. (lymetalk.net)
In this study of 1261 referred patients, 1061 had no findings of active Lyme disease, with 690 receiving other diagnoses resulting in 405 having newly diagnosed medical conditions, 134 attributed to pre-existing medical issues, and 151 with both new and pre-existing conditions. (lymetalk.net)
Post-treatment Lyme Disease symptoms patients exhibited levels of fatigue, musculoskeletal pain, sleep disturbance, and depression which were both clinically relevant and statistically significantly higher than controls. (lymetalk.net)
We are committed to advancing innovative therapeutics for patients with rheumatic diseases, and we look forward to the European Commission's decision later this year. (jnj.com)
Unlike ankylosing spondylitis, which is another type of AxSpA, patients with nr-AxSpA may not present with traditional X-ray evidence of structural damage in sacroiliac joins the spine. (jnj.com)
Accordingly, pain management or any other treatment in these patients requires proper understanding about the biomechanics of the hip and the spinal and their corresponding interactions. (ac.ir)
Pain distribution and response to total hip arthroplasty: a prospective observational study in 113 patients with end-stage hip disease. (ac.ir)
however, regulations for treating patients with cells and tissues that are based on evidence could help to address challenges relating to therapy, safety, and efficacy. (nationalacademies.org)
Fig. 1: Radiographic appearance of kidney stone disease in three patients. (nature.com)
In addition, once such patients develop PSVA, they often experience unbearable severe pain, spinal deformity and loss of stability, and neurological deficits. (biomedcentral.com)
All patients with postoperative spinal infections between January 2010 and July 2020, who primarily underwent VA, were examined after obtaining approval from the institutional review board of the hospital. (biomedcentral.com)
Both physicians conducted autopsies on their patients and found severe atrophy of the ventral roots of the spinal cord. (medscape.com)
Le présent article décrit les manifestations cliniques, le diagnostic et la prise en charge de la schistosomiase médullaire chez cinq patients admis dans les hôpitaux Shaab et Ibn Khaldoun de Khartoum entre 1997 et 2007. (who.int)
For example, only 1 in 10 people who need assistive products has access to 1 Diseases affecting small numbers of patients, including diseases of genetic origin, infrequent forms of cancer, autoimmune diseases, toxic and/or infectious diseases, and congenital deformities. (who.int)
Rare and orphan diseases affect a small number of patients and their management presents specific challenges, including the need for complex and specialized care. (who.int)

The spinal cord is a long bundle of nerves and cells that extends from the lower portion of the brain to the lower back. (medicalnewstoday.com)
There are 31 pairs of spinal nerves. (medicalnewstoday.com)
The spinal cord nerves also transmit messages to the brain from the body, such as sensations of touch, pressure, and pain. (medicalnewstoday.com)
Low-level electrical current to nerves and muscle-motor fibers via electrodes placed on the skin (TENS) is effective in the muscle spasms found in intervertebral disc disease. (seniorpetproducts.com)
Eye exams to look for evidence of damage to the optic nerves. (hartfordhealthcare.org)
An epidural spinal injection (ESI), which involves injecting medicine directly into the space around your spinal nerves or spinal cord. (medlineplus.gov)
Surgery is done to relieve pressure on the nerves or spinal cord. (medlineplus.gov)
Surgery may include removing a bulging disk , removing part of the vertebra bone , or widening the canal and openings where your spinal nerves are located . (medlineplus.gov)
During some spinal surgeries, the surgeon will remove some bone to create more room for your spinal nerves or spinal column. (medlineplus.gov)

A thorough neurological examination is fundamental to evaluate the spinal cord function and provide the client with a reasonable prognosis. (vin.com)
citation needed] Progressive neurological disease is the hallmark of Niemann-Pick type C disease, and is responsible for disability and premature death in all cases beyond early childhood. (wikipedia.org)
If a spinal injury is detected, a neurological assessment must be made, even if incomplete, and repeated regularlyprior to urgent transfer to an appropriate spinal injury service. (boa.ac.uk)
The operation may be one of the effective treatments if the patient suffers from intolerable severe pain, neurological deficits, and damage to spinal stability. (biomedcentral.com)

O'Connor P. Incidence and patterns of spinal cord injury in Australia. (medscape.com)

Early chiropractors believed that 100% of disease was caused by subluxation. (sciencebasedmedicine.org)
Today most chiropractors still claim that subluxations cause interference with the nervous system, leading to suboptimal health and causing disease. (sciencebasedmedicine.org)
When chiropractors use spinal manipulation therapy for symptomatic relief of mechanical low back pain, they are employing an evidence-based method also used by physical therapists, doctors of osteopathy, and others. (sciencebasedmedicine.org)
Jenna Duehr adds: 'The evidence is clear that chiropractors can play an important role in evidence-informed, people-centred, interprofessional and collaborative care for spinal health. (voxy.co.nz)
New Zealand's chiropractors have launched a public website (https://chiropracticnz.org), taking the lead to inform, educate and inspire people to enhance their overall health and prevent pain and disability by improving their posture, addressing spinal problems and engaging in physical activity. (voxy.co.nz)
Spinal decompression devices use the same basic principle of spinal traction that has been offered by chiropractors, osteopaths, and other appropriately trained health professionals for many years. (spine-health.com)

Animal models offer a unique opportunity to study the pathogenesis of neurologic diseases afflicting both humans and animals. (stanford.edu)

The Centers for Disease Control and Prevention (CDC) called for national heightened awareness, particularly for rapid onset of a traumatic limb weakness along with radiologic evidence of gray matter lesions, coined acute flaccid myelitis (AFM) ( 2 , 5 - 7 ). (cdc.gov)
AFM is an illness that's characterized by the sudden onset of flaccid weakness in one or more extremities and also by distinct longitudinal gray matter lesions in the spinal cord. (cdc.gov)

The disease can eventually progress to include bone destruction, which can lead to spinal deformity and dysfunction. (jnj.com)

The cord fills the whole spinal canal at the injury level and leads to further secondary ischemia. (medscape.com)
We report a case of a 9-month-old boy increased signal within the whole spinal who presented with a 1 month evolving his- cord was observed. (who.int)
Figure 1 T2 weighted sagittal magnetic resonance image showing increased signal within the whole spinal cord and medulla oblongata mg/dL is the normal range for cerebrospinal fluid protein in our laboratory) and glu- cose content was 58 mg/dL (simultane- ous blood sugar 90 mg/dL). (who.int)

Priapism in acute spinal cord injury. (medscape.com)
Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. (medscape.com)
Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. (medscape.com)
National Acute Spinal Cord Injury Study. (medscape.com)

Spinal infections involve pyogenic or granulomatous infections of the vertebral column, intervertebral discs, the dural sac or the epidural space. (wheelessonline.com)
Covering the spinal cord and its protective layers is the vertebral column, or the spinal bones. (medicalnewstoday.com)

Following traumatic spinal cord injury (SCI), one of the main concerns from cat-owners is whether their cat can recover (i.e., a "functional pet" that can walk, able to regain urinary/fecal continence). (vin.com)

Most researchers regard MS as a primary inflammatory disease, in which demyelination and tissue injury is driven by immune mediated mechanisms throughout all different stages and in all different courses ( 6 , 7 ). (frontiersin.org)
McDonald JW, Sadowsky C. Spinal-cord injury. (medscape.com)
The development of evidence-informed physical activity guidelines for adults with spinal cord injury. (medscape.com)
Biering-Sorensen B, Kristensen IB, Kjaer M, Biering-Sorensen F. Muscle after spinal cord injury. (medscape.com)
Efficacy and safety of vardenafil in men with erectile dysfunction caused by spinal cord injury. (medscape.com)
Spinal cord injury medicine. (medscape.com)
5. Preserving wellness and independence of the aging patient with spinal cord injury: a primary care approach for the rehabilitation medicine specialist. (medscape.com)
Hagen EM, Faerestrand S, Hoff JM, Rekand T, Gronning M. Cardiovascular and urological dysfunction in spinal cord injury. (medscape.com)
MRI is the urgent investigation of choice for spinal cord injury. (boa.ac.uk)
This report supersedes the 1990 report, which included infectious diseases and one noninfectious condition (i.e., spinal cord injury). (cdc.gov)
In order to rule out spinal cord pathol- lar immune derangements that potentially ogy, craniospinal magnetic resonance imag- result in neuronal injury and demyelina- ing (MRI) was obtained immediately. (who.int)

Spinal fusion surgery involves the fusion of two or more vertebral bones, and is a standard of care for spinal deformities and conditions such as radiculopathy, myelopathy and spondylolisthesis. (surreybackandjointclinic.co.uk)

In general, any SCI patient presented with paraplegia/tetraplegia without deep pain perception (DPP), the prognosis for functional recovery is guarded as the "spinal cord function" is completely blocked or transected at the injured site. (vin.com)

Relatively little evidence exists on predictive factors for the spontaneous regression of lumbar disc herniation (LDH), although it is a well-documented phenomenon. (nih.gov)

Spine infections are rare infections that can involve the intervertebral disc space (discitis), the vertebral bones, the spinal canal or adjacent soft tissues. (wheelessonline.com)
A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group. (nih.gov)
Move Your Spine" encourages people of all ages, in all nations, to get active and support their spinal health through movement. (voxy.co.nz)
Spinal Decompression Therapy involves stretching the spine, using a traction table or similar motorized device, with the goal of relieving back pain and/or leg pain. (spine-health.com)
European Spine Journal 18(12):1843-50, 2009] Thus, there is insufficient evidence that spinal decompression therapy is as effective, or more effective, than less expensive manual methods in treating back pain or injured herniated discs. (spine-health.com)
The spinal cord does not extend for the entire length of the spine. (medicalnewstoday.com)
The coexistence of degenerative disease of hip and spine or other diseases can significantly alter spinopelvic alignment. (ac.ir)

The difficulties in making diagnoses for low back pain tend to focus on objective evidence of disease. (cdc.gov)

We can learn much by studying the temporal and spatial evolution of the lesions in the nervous system in spontaneously occurring or induced diseases in animals.The rapid development of the dog genome map brings an important benefit to the study of inherited canine diseases. (stanford.edu)
Evidence obtained so far indicate major differences between RRMS and progressive MS, but no essential differences between SPMS and PPMS, with the exception of a lower incidence in the global load of focal white matter lesions and in particular in the presence of classical active plaques in PPMS. (frontiersin.org)

In the panel's previous vote against the drug application, members cited several issues with the study, concluding that it did not offer persuasive or robust evidence of efficacy. (medscape.com)
Non-surgical spinal decompression therapy: Does the scientific literature support efficacy claims made in the advertising media? (spine-health.com)

As the prevalence of post-treatment Lyme Disease symptoms continues to rise, there will be an increased need for physician education to more effectively identify and manage post-treatment Lyme Disease symptoms as part of integrated patient care. (lymetalk.net)
A second paper published in 2021 , and again lead by Alison W. Rebman at Johns Hopkins University School of Medicine made many observations into the symptoms of Lyme Disease. (lymetalk.net)

As uniform case definitions are adopted, the incidence of reported diseases in different geographic areas may be more meaningfully compared. (cdc.gov)
16. Legaye J, Duval-Beaupere G, Hecquet J, Marty C. Pelvic incidence: a fundamental pelvic parameter for threedimensional regulation of spinal sagittal curves. (ac.ir)

This article covers the key anatomy of the spinal cord and its functions. (medicalnewstoday.com)
Most spinal diseases can be treated via a single surgical approach with the familiarity of spinal anatomy and the highly developed surgical instruments related to spinal surgery. (biomedcentral.com)

The MMWR series of publications is published by the Epidemiology Program Office, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA 30333. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
I'm Commander Ibad Khan and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
Dr. Janell Routh is a medical officer on the acute flaccid myelitis team at the Centers for Disease Control and Prevention. (cdc.gov)
Adriana Lopez is an epidemiologist on the acute flaccid myelitis team at the Centers for Disease Control and Prevention. (cdc.gov)
Finally, Dr. Manisha Patel is the acute flaccid myelitis team lead at the Centers for Disease Control and Prevention. (cdc.gov)

Public health officials rely on health providers, laboratories, and other public health personnel to report the occurrence of notifiable diseases to state and local health departments. (cdc.gov)
Notifiable Diseases Surveillance System (NNDSS). (cdc.gov)
Updated final reports are published annually in the Sum- mary of Notifiable Diseases. (cdc.gov)
CDC and the Council of State and Territorial Epidemiologists (CSTE) have established a policy that requires state health departments to report cases of selected diseases ( Table 1 ) to CDC's National Notifiable Diseases Surveillance System (NNDSS) (1,2). (cdc.gov)
Data for nationally notifiable diseases reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly in the Morbidity and Mortality Weekly Report (MMWR). (cdc.gov)

Acute flaccid myelitis (AFM) is a polio-like disease that results in paralysis in previously healthy persons. (cdc.gov)
Loss of these cells results in a progressive lower motor neuron disease that has no sensory involvement and that is manifested as hypotonia, weakness, and progressive paralysis. (medscape.com)
Nor was it possible to obtain any serological evidence of an association of the virus with the lumbar paralysis. (cdc.gov)

SMAs were first described in the 1890s, by Guido Werdnig, a physician from the University of Vienna, in his lecture "On a Case of Muscular Dystrophy with Positive Spinal Cord Findings. (medscape.com)
The inferior olivary nucleus of pharmacological evidence of these findings, neurotensin, e. (higienistasvitis.com)

Rather than a rapidly lethal disease, SMA type 1, the most severe form with the earliest onset of SMA, has become a disease in which long-term event-free survival with the acquisition of important motor milestones is likely. (dovepress.com)
citation needed] In the terminal stages of Niemann-Pick type C disease, the patient is bedridden, with complete ophthalmoplegia, loss of volitional movement and severe dementia. (wikipedia.org)
A second period of EV-D68 circulation, again associated with severe respiratory disease, was described during late summer and fall of 2016, although 2 studies suggest lower levels of circulation during that period than in 2014 ( 8 , 9 ). (cdc.gov)
Our data suggest that longer AR CAG score is associated with more severe COVID-19 disease. (kennedysdisease.org)

As in children with AFM, these EV-D68-infected mice had a loss of motor neurons in the anterior horns of spinal cord segments corresponding to paralyzed limbs. (cdc.gov)
They also found histologic evidence of loss of motor neurons in the anterior horn cells of this region. (medscape.com)
Terms in the spinal cord MRI report such as "affecting gray matter," "affecting the anterior horn or anterior horn cells," "affecting the central cord," "anterior myelitis," or "poliomyelitis" would all be consistent with this terminology. (cdc.gov)

The limited research evidence across manual therapies is not supportive of practitioners making advertising claims that they can effectively treat non-musculoskeletal conditions. (ahpra.gov.au)
[16] [17] Additionally, there are many alternative medicine therapies, but there is not enough evidence to recommend them confidently. (wikipedia.org)

There is mounting evidence that body manipulation and massage can noticeably decrease discomfort and improve function in many dogs. (seniorpetproducts.com)
[6] Non-medication based treatments include superficial heat , massage , acupuncture , or spinal manipulation . (wikipedia.org)

Niemann-Pick type C (NPC) (colloquially, "Childhood Alzheimer's") is a lysosomal storage disease associated with mutations in NPC1 and NPC2 genes. (wikipedia.org)
Comparative gene mapping among human, murine, and canine genomes have the potential to rapidly identify mutations that underlie various disease syndromes. (stanford.edu)

Primary spinal infections are described as infections of the vertebrae that are not secondary to an operation. (wheelessonline.com)

This article provides an overview of nonsurgical spinal decompression therapy and its role in treatment of lower back pain and neck pain. (spine-health.com)

The rationale for the study is well supported by available scientific and medical evidence. (cms.gov)

The mnemonic "PAINT" has been used to divide the causes of restrictive lung disease into pleural, alveolar, interstitial, neuromuscular, and thoracic cage abnormalities. (medscape.com)
Restrictive lung diseases are characterized by a reduction in FRC and other lung volumes because of pathology in the lungs, pleura, or structures of the thoracic cage. (medscape.com)

Normal gait, spinal pain only. (vin.com)

Sept. 6, 2022 - A team of authors published a study estimating the budget impact for the National Health Service in England of screening trials for spinal cord stimulation for neuropathic pain. (neuromodulation.com)
Sept. 1, 2022 - The device company Nevro announced positive coverage updates from U.S. healthcare insurance providers concerning the treatment of painful diabetic neuropathy with spinal cord stimulation. (neuromodulation.com)
Aug. 30, 2022 - A column gives an overview of spinal cord stimulation. (neuromodulation.com)
An April 2022 study in The American journal of medicine comes to us from the University of Iowa Hospitals and Clinics and the Johns Hopkins University School of Medicine with the suggestion that while prior studies have demonstrated that Lyme disease is frequently over-diagnosed. (lymetalk.net)

The other view suggests that MS is a primary neurodegenerative disease, which is modified and amplified by the inflammatory process. (frontiersin.org)

Last, virus isolated from spinal cords of infected mice transmitted disease when injected into naive mice ( 15 ). (cdc.gov)

Looking at the spinal cord cross-section, the top wings of the gray matter "butterfly" reach toward the spinal bones. (medicalnewstoday.com)

The previously mentioned tendency of medulloblastoma to spread via CSF pathways can lead to diffuse "sugar coating" of the subarachnoid space and to nodular growths along the spinal cord or even ventricular surfaces. (medscape.com)

ABSTRACT Schistosomiasis of the spinal cord is an uncommon but potentially curable form of schistosomiasis, if diagnosed and managed early. (who.int)

Heers, H. & Turney, B. W. Trends in urological stone disease: a 5-year update of hospital episode statistics. (nature.com)

RÉSUMÉ La schistosomiase médullaire est une forme rare mais potentiellement curable de la schistosomiase, lorsque le diagnostic a été posé au début de l'affection et que la prise en charge a été rapide. (who.int)
This systematic review and meta-analysis of the role of ultrasound in the diagnosis of intestinal malrotation and volvulus found moderate quality evidence for ultrasound as the first-line diagnostic test for this emergency condition in children. (bmj.com)

Anatomy5

Diseases12

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Disciplines and Occupations1

Named Groups1

Health Care1

Brain and spinal cord6

Muscular atrophy8

Amyotrophic Lateral S5

Stenosis7

Clinical23

Chronic13

Affect the spinal cord1

Cervical3

Degeneration4

Complications3

Disorders8

Injuries4

Nerve6

Trauma6

Chiropractic8

Multiple Sclerosis2

Lumbar vertebrae1

Patients19

Nerves9

Neurological4

Patterns of spinal1

Chiropractors6

Neurologic diseases1

Gray matter lesions2

Deformity1

Whole spinal3

Acute spinal4

Vertebral column2

Traumatic spinal1

Injury11

Deformities1

Prognosis1

Disc herniation1

Spine7

Diagnoses1

Lesions2

Efficacy2

Symptoms2

Incidence2

Anatomy2

Centers for Dis6

Notifiable Diseases5

Paralysis3

Findings2

Severe4

Anterior3

Therapies2

Manipulation2

Mutations2

Described as infecti1

Neck1

Scientific1

Thoracic2

Gait1

20224

Neurodegenerative disease1

Cords1

Bones1

Subarachnoid1

Abstract1

Urological1

Diagnostic2