• exhibit
  • In particular, females with Turner's syndrome (TS) who have only one X-chromosome exhibit deficits of spatial ability whereas males with Klinefelter's syndrome (KS) who possess a supernumerary X-chromosome are delayed in acquiring words. (ox.ac.uk)
  • correctly
  • These control mechanisms, called `checkpoints', inhibit the transition to the next cell cycle phase if the events of the previous phase have not been correctly executed. (biologists.org)
  • development
  • The findings suggest that the number of sex chromosomes influences the development of brain asymmetry not simply to modify the torque but in a complex pattern along the antero-posterior axis. (ox.ac.uk)
  • pair
  • They then compared the number of mutations between the X form and the Y form of a pair of X-Y genes to come up with rough estimates of when they were last alike, giving them a 'geologic' snapshot of sex chromosomes. (abc.net.au)
  • least
  • The first events that created the sex chromosomes had been thought to have occurred at least 170 million years ago," says researcher Dr David Page. (abc.net.au)
  • move
  • In the 'extrusion-capture' model, replication through an anchored replisome provides the force to move daughter chromosomes to the poles ( Lemon and Grossman, 2001 ). (wiley.com)
  • appear
  • Most likely this suppression was the result of a series of chromosomal inversions on the Y chromosome, which would also explain why the genes appear to be in order on the X but scrambled on the Y," Page explains. (abc.net.au)
  • male
  • However, in a ZW system one can separate the effect of the hemizygous chromosome from the male-biased mutations, providing an excellent system for understanding the evolution of SCD. (royalsocietypublishing.org)
  • research
  • Research published in this week's Science reveals that the Y chromosome developed from an X-like ancestor around 300 million years ago. (abc.net.au)
  • women
  • Specifically, we tested Crow's prediction that the magnitude of the brain torque (i.e., a combination of rightward frontal and leftward occipital asymmetry) would, as a function of sex chromosome dosage, be respectively decreased in TS women and increased in KS men, relative to genotypically normal controls. (ox.ac.uk)
  • model
  • Our projects primarily use the yeast, Saccharomyces cerevisiae, as a model to elucidate conserved aspects of eukaryotic chromosome biology. (omrf.org)