• fungi
  • As a result, yeast cells lacking the DAP1 gene are highly sensitive to antifungal drugs This function is conserved between the unrelated fungi S. cerevisiae and S. pombe. (wikipedia.org)
  • Fungal effectors are secreted by pathogenic or beneficial fungi into and around host cells by invasive hyphae to disable defense components or facilitate colonization. (wikipedia.org)
  • In fungi C5SD catalyzes the dehydration of episterol as a step in the synthesis of ergosterol, a sterol that regulates cell membrane fluidity and permeability. (wikipedia.org)
  • These organisms are classified as a kingdom, Fungi, which is separate from the other eukaryotic life kingdoms of plants and animals. (wikipedia.org)
  • A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. (wikipedia.org)
  • Biology
  • Due to its mitogenic activity, PDGF is useful as an important component of a defined medium for the growth of mammalian cells in culture, making it a valuable research reagent with multiple applications in the study of animal cell biology. (google.com.au)
  • pathogenic
  • Consequently, in both the pathogenic fungus Candida albicans and model organism S. cerevisiae mutations in the gene encoding C-5 sterol desaturase (ERG3) allow the cell to avoid synthesizing the toxic sterol products and have been shown to confer azole resistance. (wikipedia.org)
  • genetic
  • This involves delivering genes into cells in order to achieve, in vivo, the synthesis of therapeutically effective gene products, e.g. in order to replace a defective gene in the event of a genetic defect. (google.es)
  • species
  • Tremella species produce hyphae that are typically (but not always) clamped and have haustorial cells from which hyphal filaments seek out and penetrate the hyphae of the host. (wikipedia.org)
  • survival
  • The website also explains that these kinases can only be activated by cyclins, making them a crucial component for the survival of every eukaryotic cell. (reference.com)
  • PGRMC1 also promotes survival in human cancer cells after treatment with chemotherapy. (wikipedia.org)
  • protein
  • When a cell is dividing, the nuclear chromatin (DNA and surrounding protein) condenses into chromosomes that are easily seen by microscopy. (cellsalive.com)
  • There are some subtypes of cyclins that are far more complex and execute different roles in the life of the eukaryotic cell, including the retinoblastoma protein known for its bond with the E2F protein. (reference.com)
  • b) isolating from the host cell a mitogenic protein, which is a PDGF BB Romodimer, expressed from said DNA construct. (google.com.au)
  • Human platelet-derived growth factor (PDGF) has been shown to be the major mitogenic protein in serum for mesenchymal derived cells. (google.com.au)
  • Progesterone inhibits apoptosis in immortalized granulosa cells, and this activity requires PGRMC1 and its binding partner, PAIR-BP1 (plasminogen activator inhibitor RNA-binding protein-1). (wikipedia.org)
  • yeast cells
  • Yeast cells lacking the DAP1 gene are sensitive to DNA damage, and heme-binding is essential for damage resistance. (wikipedia.org)
  • Due to its simplicity, specificity and sensitivity, RT-PCR is used in a wide range of applications from experiments as simple as quantification of yeast cells in wine to more complex uses as diagnostic tools for detecting infectious agents such as the avian flu virus. (wikipedia.org)
  • These spores are smooth, globose to ellipsoid, and germinate by hyphal tube or by yeast cells. (wikipedia.org)
  • Conidiophores are often present, producing conidiospores that are similar to yeast cells. (wikipedia.org)
  • involves
  • This involves numerous stages - the nuclear membrane disintegrates then the chromosomes are sorted and separated to ensure that each daughter cell receives two sets (a diploid number) of chromosomes. (news-medical.net)
  • molecule
  • A molecule Specific for a receptor on the surface of the target cell is introduced onto the surface of the virus or cell. (google.es)
  • selective
  • Viruses or cells are targeted for selective internalization into a target in vive. (google.es)
  • The method provides vectors for selective delivery of nucleic acids to specific cell types in vivo and a means to alter the tropism of an infectious agent. (google.es)
  • secretory
  • Cell secretions - e.g. hormones, neurotransmitters - are packaged in secretory vesicles at the Golgi apparatus. (cellsalive.com)
  • The secretory vesicles are then transported to the cell surface for release. (cellsalive.com)
  • synthesis
  • This is well documented by numerous studies of platelet extracts or purified PDGF induction of either cell multiplication or DNA synthesis (a prerequisite for cell division) in cultured smooth muscle cells, fibroblasts and glial cells (Ross et al. (google.com.au)
  • cone
  • The seed of a vascular plant is a small package produced in a fruit or cone after the union of male and female reproductive cells. (wikipedia.org)
  • monocytes
  • Studies have shown that hosts with higher levels of immune response cells such as monocytes/macrophages, dendritic cells, and invariant natural killer (iNK) T-cells exhibited greater control of fungal growth and protection against systemic infection. (wikipedia.org)
  • gene
  • There is a need for an efficient system of introducing nucleic acid into living cells particularly in gene therapy. (google.es)
  • By this is meant viruses in which the gene to be expressed in the cell has been integrated in the genome by recombinant methods. (google.es)
  • tumor
  • Single-cell next-generation sequencing enables cell-by-cell analysis of the genomic sequence, the detection of single nucleotide variants, copy number variations and structural variants for tumor or cell profiling and cell evolution analysis. (qiagen.com)
  • binds
  • The modified virus or cell binds the receptor in vive and is internalized by the target cell. (google.es)
  • hyphal
  • It has been shown that cytoplasmic effectors can move through a few layers of plant cells, probably a way to prepare them for hyphal invasion. (wikipedia.org)
  • fibroblasts
  • The released PDGF is thought to chemotactically attract fibroblasts and smooth muscle cells to the site of injury and to induce their focal proliferation as part of the process of wound repair (Ross and Glomset, N. Eng. (google.com.au)
  • growth
  • Dormant seeds are ripe seeds that do not germinate because they are subject to external environmental conditions that prevent the initiation of metabolic processes and cell growth. (wikipedia.org)
  • However
  • However, the hidden tails of the phosopholipids are "hydrophobic" (water fearing), so the cell membrane acts as a protective barrier to the uncontrolled flow of water. (cellsalive.com)
  • However some C. neoformans cells may survive within the macrophages. (wikipedia.org)
  • cervix
  • PGRMC1 is over-expressed in breast tumors and in cancer cell lines from the colon, thyroid, ovary, lung, and cervix. (wikipedia.org)