While the prototypical viruses in Monodnaviria have circular ssDNA genomes and replicate via RCR, some have linear ssDNA genomes with different replication methods, including the families Parvoviridae and Bidnaviridae, assigned to the phylum Cossaviricota of the kingdom Shotokuvirae. (wikipedia.org)
Parvoviruses are a family of animal viruses that constitute the family Parvoviridae . (mdwiki.org)
Encode5
Monodnaviria is a realm of viruses that includes all single-stranded DNA viruses that encode an endonuclease of the HUH superfamily that initiates rolling circle replication of the circular viral genome. (wikipedia.org)
Viruses in Monodnaviria appear to have come into existence independently multiple times from circular bacterial and archaeal plasmids that encode the HUH endonuclease. (wikipedia.org)
All prototypical viruses in Monodnaviria encode an endonuclease of the HUH superfamily. (wikipedia.org)
36. The Most Complex Virus Can Encode ---- Proteins. (iubians.com)
Parvoviruses are believed to be descended from ssDNA viruses that have circular genomes that form a loop because these viruses encode a replication initiator protein that is related to NS1 and have a similar replication mechanism. (mdwiki.org)
Parvovirus4
A divergent parvovirus genome was the only eukaryotic viral sequence detected in feces of a Tunisian child with unexplained diarrhea. (cdc.gov)
Parvo", "parvovirus", and "parvo virus" redirect here. (mdwiki.org)
Parvovirus virions are small compared to most viruses, at 23-28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface. (mdwiki.org)
Animal parvoviruses were first discovered in the 1960s, including minute virus of mice , which is frequently used to study parvovirus replication. (mdwiki.org)
Single-stranded3
Parvoviruses are small icosahedral viruses with linear single-stranded DNA genomes of ≈5 kb that are associated with a wide spectrum of illnesses in humans and animals. (cdc.gov)
Viruses descended from such viruses are also included in the realm, including certain linear single-stranded DNA (ssDNA) viruses and circular double-stranded DNA (dsDNA) viruses. (wikipedia.org)
Monodnaviria is a portmanteau of mono, from Greek μόνος [mónos], meaning single, DNA from deoxyribonucleic acid (DNA), referencing single-stranded DNA, and the suffix -viria, which is the suffix used for virus realms. (wikipedia.org)
The prototypic members of Monodnaviria are often called CRESS-DNA, or CRESS DNA, viruses, which stands for "circular Rep-encoding ssDNA" viruses. (wikipedia.org)
The HUH endonuclease of ssDNA viruses is often called the replication initiation protein, or simply Rep, because its cleavage of a specific site in the viral genome initiates replication. (wikipedia.org)
In conclusion, this study does not support the hypothesis that the investigated diarrhoea was caused by known mammalian viruses. (slu.se)
The results do, however, indicate that known mammalian viruses were present in the intestine as early as 24-48 hours after birth, indicating immediate infection post-partum or possibly transplacental infection. (slu.se)
Viral3
No other eukaryotic viral sequences were identified from 260,000 unique sequence reads from this patient. (cdc.gov)
The aim of the present study was to use viral metagenomics to examine a potential viral involvement in this diarrhoea and to describe the intestinal virome with focus on eukaryotic viruses. (slu.se)
8. The Most Common Proteins Of Virus Are _____ Which Is Responsible For The Viral Movement To Neighbouring Cells. (iubians.com)
Prokaryotes1
Viruses in the first three kingdoms infect prokaryotes, and viruses in Shotokuvirae infect eukaryotes and include the atypical members of the realm. (wikipedia.org)
Parvoviruses1
Another group of viruses called bidnaviruses appear to be descended from parvoviruses. (mdwiki.org)
Realm2
Eukaryotic viruses in the realm appear to have come into existence multiple times via genetic recombination events that merged deoxyribonucleic acid (DNA) from the aforementioned plasmids with capsid proteins of certain RNA viruses. (wikipedia.org)
The prototypic members of the realm are often called CRESS-DNA viruses. (wikipedia.org)
Family1
It was not possible to associate a particular virus family with the investigated diarrhoea. (slu.se)
Vector1
In medicine, recombinant adeno-associated viruses (AAV) have become an important vector for delivering genes to the cell nucleus during gene therapy . (mdwiki.org)
Copies1
To develop a novel DNA vaccine with high efficacy against PCV2d virus, we fused the ORF2 of PCV2d to three copies of the minimum-binding domain of the complement C3 cascade terminal component, C3d-P28. (biomedcentral.com)
Infect6
Viruses in the first three kingdoms infect prokaryotes, and viruses in Shotokuvirae infect eukaryotes and include the atypical members of the realm. (wikipedia.org)
Viruses encoding a replication-associated protein (Rep) within a covalently closed, single-stranded (ss)DNA genome are among the smallest viruses known to infect eukaryotic organisms, including economically valuable agricultural crops and livestock. (peerj.com)
Although members of viral and satellite families known to infect plants ( Geminiviridae , Nanoviridae , Alphasatellitidae ) were not identified in this study, these plant-infecting CRESS DNA viruses and replicons are transmitted by hemipterans. (peerj.com)
Viruses that infect eukaryotic cells within the human fecal virome have been identified to belong to families Astroviridae , Anelloviridae , Picornaviridae , Caliciviridae , and Herpesviridae , among others [ 2 , 3 ]. (biomedcentral.com)
therefore, the discovery of viruses that specifically infect human cells may be better achieved by analysis of less accessible tissue and cells, rather than feces or bodily fluids, where they are likely scarce. (biomedcentral.com)
A family of DNA plant viruses that infect eukaryotic algae. (nih.gov)
Genome3
A divergent parvovirus genome was the only eukaryotic viral sequence detected in feces of a Tunisian child with unexplained diarrhea. (cdc.gov)
Monodnaviria is a realm of viruses that includes all single-stranded DNA viruses that encode an endonuclease of the HUH superfamily that initiates rolling circle replication of the circular viral genome. (wikipedia.org)
The HUH endonuclease of ssDNA viruses is often called the replication initiation protein, or simply Rep, because its cleavage of a specific site in the viral genome initiates replication. (wikipedia.org)
SsDNA6
The family Circoviridae comprises viruses with small, circular, single-stranded DNA (ssDNA) genomes, including the smallest known animal viruses. (nih.gov)
Viruses descended from such viruses are also included in the realm, including certain linear single-stranded DNA (ssDNA) viruses and circular double-stranded DNA (dsDNA) viruses. (wikipedia.org)
The prototypic members of Monodnaviria are often called CRESS-DNA, or CRESS DNA, viruses, which stands for "circular Rep-encoding ssDNA" viruses. (wikipedia.org)
While the prototypical viruses in Monodnaviria have circular ssDNA genomes and replicate via RCR, some have linear ssDNA genomes with different replication methods, including the families Parvoviridae and Bidnaviridae, assigned to the phylum Cossaviricota of the kingdom Shotokuvirae. (wikipedia.org)
Although circular Rep-encoding ssDNA (CRESS DNA) viruses are a widespread group for which our knowledge is rapidly expanding, biased sampling towards vertebrates and land plants has limited our understanding of their diversity and evolution. (peerj.com)
CRESS DNA2
The prototypic members of the realm are often called CRESS-DNA viruses. (wikipedia.org)
CRESS-DNA viruses are associated with a wide range of diseases, including diseases in economically important crops and a variety of diseases in animals. (wikipedia.org)
Bacterial3
Viruses in Monodnaviria appear to have come into existence independently multiple times from circular bacterial and archaeal plasmids that encode the HUH endonuclease. (wikipedia.org)
We do not yet know the eukaryotic cell or bacterial host of most viruses, and there is no universal 16S ribosomal RNA equivalent, as in bacteria, allowing for rapid taxonomic characterization. (biomedcentral.com)
However, since the virome consists of both temperate bacteriophages within bacterial genomes and free VLPs, both total and VLP sequencing will likely provide greater representation of all viruses. (biomedcentral.com)
Linear single-stranded1
Parvoviruses are small icosahedral viruses with linear single-stranded DNA genomes of ≈5 kb that are associated with a wide spectrum of illnesses in humans and animals. (cdc.gov)
Species1
Viruses infecting animals, plants, fungi, and protozoans (collectively eukaryotic viruses) number around 100 million species while those infecting bacteria are estimated at 10 trillion, yet a large proportion remain unannotated. (biomedcentral.com)
Vast1
1) The vast majority of viruses share little to no homology with annotated viruses in reference databases. (biomedcentral.com)
Https1
While the NCBI Virus Portal ( https://www.ncbi.nlm.nih.gov/labs/virus/vssi/#/ ) is reporting new annotations at an exponential rate, virologists have struggled to distinguish clear classes and kingdoms for most of the virosphere, with the exception of a recently published taxonomic hierarchy [ 8 ]. (biomedcentral.com)
Identification2
While we are still characterizing what constitutes a healthy or diseased virome, an exciting next step is to move beyond correlations and toward identification of specific viruses and their precise mechanisms of beneficial or harmful immunomodulation. (biomedcentral.com)
Technologies such as metagenomics have only recently enabled identification of viruses in healthy human tissues. (biomedcentral.com)
Discovery1
The late start for viruses in the commensal microorganism field is in large part due to our inability to readily culture or detect them, as was the case during the discovery of the influenza virus. (biomedcentral.com)