• Large-scale genomics and transcriptomics approaches have been proven to enable the identification of pathogenicity genes in fungi affecting humans or plants [ 8 ], which makes them valuable tools towards a better understanding of fungal infection mechanisms. (biomedcentral.com)
  • These rapid adaptations in fungi provide excellent models for studying general processes of eukaryotic genome evolution, including the functional and ecological impact of horizontal gene transfer 1 and changes in metabolism 2 . (nature.com)
  • In fact, fungi are the most diverse group of eukaryotic organisms. (databasefootball.com)
  • As many as thirty percent of genes associated with human diseases have similar copies in fungi making it possible to understand important human genes using experimental fungal organisms. (databasefootball.com)
  • These fungi feature a short life cycle and a simple genome which researchers can compare to other eukaryotic groups, such as humans. (databasefootball.com)
  • By systematically analyzing 304 genomes from all major fungal groups, together with a broad range of eukaryotic outgroups, we have identified 188 novel orthogroups associated with major changes during the evolution of fungi. (biomedcentral.com)
  • The overall picture is one of a relatively small number of novel genes appearing at major evolutionary transitions in the phylogeny of fungi, with most arising de novo and horizontal gene transfer providing only a small additional source of evolutionary novelty. (biomedcentral.com)
  • Our findings contribute to an increasingly detailed portrait of the gene families that define fungal phyla and underpin core features of extant fungi. (biomedcentral.com)
  • Despite the popularity of fungi as eukaryotic model systems, several questions on their phylogenetic relationships continue to be controversial. (umontreal.ca)
  • In an effort to develop a complete understanding of the organization and gene content of chromosome ends in a number of fungi, we developed efficient methods for the identification and targeted cloning of telomeres. (uky.edu)
  • More recently he has been trying to understand the adaptations and evolutionary history of an oomycete-relative, Hyphochytrium catenoides and a fungal-eye complex present in chytrid fungi, specifically in Blastocladiella emersonii . (evomics.org)
  • This has resulted in reciprocal adaptations, like specialized morphologies and metabolic capabilities in the fungi and mycetangia and behaviors for fungal management in the beetles. (iufro-lisbon2022.com)
  • Further, we analyse what role that the cellular changes to the plant, and the plant genes doing it, have for the ability of plants to be promoted by growth- and protection-promoting fungi. (lu.se)
  • Overview of Fungal Infections Fungi are eukaryotic organisms that exist as yeast, molds, or both forms. (msdmanuals.com)
  • Novel eukaryotic genomes can be analyzed by the self-training GeneMark-ES . (gatech.edu)
  • Patrick Wincker also heads LAGE , which studies not only the structure and evolution of eukaryote genomes but also the structure and function of environmental eukaryotic communities using bioinformatics methodologies. (cea.fr)
  • Transfers of a single gene, a complete metabolic pathway 10 , whole chromosomes 11 or even cases of the integration of almost complete genomes from bacterial endosymbionts into their eukaryotic hosts 12 have been described. (nature.com)
  • It is currently mainly tuned for plant and fungal genomes. (vandepeerlab.org)
  • It has become increasingly clear that eukaryotic genomes are pervasively transcribed and translated. (yeastorfanproject.com)
  • Thousands of small, evolutionarily novel polypeptides expand the coding potential of fungal, plant and animal genomes beyond established protein-coding genes. (yeastorfanproject.com)
  • In view to find putative mitochondrial genes in alternative reading frames on both coding and "presupposed" non-coding strands, numerous complete mtDNA genomes have been analyzed. (biomedcentral.com)
  • Gene fragmentation and RNA editing without borders: eccentric mitochondrial genomes of diplonemids. (umontreal.ca)
  • Unusual mitochondrial genomes and genes. (umontreal.ca)
  • In: Organelle Genetics 2012, Part 2: evolution of organelle genomes and gene expression (C. Bullerwell, ed), Springer-Verlag Heidelberg, Germany, p. 41-77. (umontreal.ca)
  • Several fungal species have been used as experimental organisms for decades. (databasefootball.com)
  • Polyamines (PAs) are ubiquitous polycations that influence normal growth, development, and stress responses in living organisms and have been shown to play a significant role in fungal pathogenesis. (usda.gov)
  • EuGene is a gene prediction software for eukaryotic organisms. (vandepeerlab.org)
  • Because of this, dimorphism has been the subject of extensive studies as a model for the differentiation processes occurring in eukaryotic organisms. (benthamscience.com)
  • Mitochondria mediate most of the energy production that occurs in the majority of eukaryotic organisms. (biomedcentral.com)
  • I also teach smaller parts of the 12 credits basic course in Botany, and the 15 credits advanced courses in Molecular Genetics and Molecular Genetics of Eukaryotic Organisms. (lu.se)
  • My research has centred on investigating fungal pathogenesis and virulence, focussing mainly on the opportunistic fungal pathogen Candida albicans and mouse models of infection. (abdn.ac.uk)
  • Initially, my research focussed on investigating pathogenesis from the fungal perspective, using experimental infection models to assay the contribution of fungal gene products in virulence. (abdn.ac.uk)
  • This e-book includes several chapters on the most important and studied fungal models, written by specialists, discussing the biology of each species or genera, the general aspects controlling their dimorphic transition, the molecular aspects involved, the use of them as models for understanding the bases of biochemical and cell differentiation, and the importance of dimorphism in pathogenesis. (benthamscience.com)
  • This e-book is recommended for scholars and researchers working or interested in human, animal and plant pathogenesis, fungal genetics, molecular biology, development, evolution, and differentiation. (benthamscience.com)
  • To dissect the epigenetic regulation of GLS pathogenesis, we characterized a histone deacetylase gene Cfhos2 in Colletotrichum fructicola , the causing agent of GLS. (biomedcentral.com)
  • Taken together, we demonstrate that Cfhos2 is a key epigenetic factor regulating appressorium development, virulence gene expression, and GLS pathogenesis in C. fructicola . (biomedcentral.com)
  • Fungal pathogenesis is a sophisticated process including infectious development of the pathogen and fungus-host interactions, which requires a fine-tuned regulation of gene expression dynamics. (biomedcentral.com)
  • Neurospora crassa, a fungus harnessed from an outbreak in French bakeries, was first used in genetics research in 1941 to detail the relationship between genes and enzymes. (databasefootball.com)
  • Neurospora crassa has been for decades a principal model for filamentous fungal genetics and physiology as well as for understanding the mechanism of circadian clocks. (dartmouth.edu)
  • Fungal Genetics and Biology 43(8): 545-559. (berkeley.edu)
  • The effects of different fluorescent pseudomonads, including some known biocontrol agents of other plant pathogens, on fungal growth of the haploid Verticillium dahliae and/or the amphidiploid Verticillium longisporum were compared on pectin-rich medium, in microfluidic interaction channels, allowing visualization of single hyphae, or on Arabidopsis thaliana roots. (frontiersin.org)
  • Chitin has also been sporadically found in structures from a diverse range of eukaryotic microorganisms, such as the cell wall of a few chlorophyta (green microalgae), the cyst wall or lorica, of ciliophora (ciliated protozoans), the theca of choanoflagellida (flagellated protozoans), and the test or cyst wall, of amoebozoa (amoeboid protozoans) [ 6 ]. (biomedcentral.com)
  • Aspergillus fumigatus is a ubiquitous saprophytic fungus, which has become the most common air-borne fungal pathogen of humans ( Tekaia and Latge, 2005 ). (frontiersin.org)
  • Candida albicans is the most important opportunistic fungal pathogen of humans. (ncl.edu.tw)
  • Among the nTARs, 146 share significant similarity with proteins that have been identified in other species suggesting that they are hitherto unidentified genes in C. graminicola . (biomedcentral.com)
  • On the negative side there are many fungal species that cause plant diseases and pose a high threat by crop loss, however some members of this fungal family also act as biocontrol agents in preventing the pathogenic members. (databasefootball.com)
  • An Insurgent Species Among the Penicillia," The Journal of Eukaryotic Microbiology 47(1), 24-28, (1 January 2000). (bioone.org)
  • The phylogenetic position of Schizosaccharomyces species has also been controversial: do they belong to Taphrinomycotina (previously known as archiascomycetes) as predicted by analyses with nuclear genes, or are they instead related to Saccharomycotina (budding yeast) as in mitochondrial phylogenies? (umontreal.ca)
  • Dimorphism can be defined as the property of different fungal species to grow in the form of budding yeasts or in the form of mycelium, depending on the environmental conditions. (benthamscience.com)
  • The physiological significance of proto-genes has not yet been systematically explored in any species. (yeastorfanproject.com)
  • This missing biology is likely to explain key molecular differences between species, to unveil novel mechanisms of evolutionary adaptation, and to shed light on the first steps of de novo gene emergence. (yeastorfanproject.com)
  • abstract = "Aspergillus fumigatus is the most pathogenic species among the Aspergilli, and the major fungal agent of human pulmonary infection. (manchester.ac.uk)
  • This comprehensive multi-species analysis contributes to the classification of fungal CHS, in particular by optimizing its robustness, consensuality and accessibility. (biomedcentral.com)
  • Thus, the secondary metabolite mediated effect of Pseudomonas isolates on Verticillium species results in a complex transcriptional response, leading to decreased growth with precautions for self-protection combined with the initiation of a change in fungal growth direction. (frontiersin.org)
  • 2005. Designing experiments using spotted microarrays to detect gene regulation differences within and among Species. (berkeley.edu)
  • Wallaby encompasses about 250 predicted genes, some of which are probably involved in competition with microorganisms. (nature.com)
  • However, it is likely that several horizontal gene transfers (HGT) also occurred in eukaryotic microorganisms and, even more surprisingly, in bacteria. (biomedcentral.com)
  • Marine bacteriophages play key roles in the community structure of microorganisms, biogeochemical cycles, and the mediation of genetic diversity through horizontal gene transfer. (biomedcentral.com)
  • If it is severe, the risk and severity of bacterial and fungal infections increase. (msdmanuals.com)
  • Sequence data of the revised genome annotation including several hundreds of novel transcripts, improved gene models and candidate genes for alternative splicing have been made accessible in a comprehensive database. (biomedcentral.com)
  • Because of our unique and long-standing expertise in gene prediction and genome annotation, as well as our expertise in documenting ancient whole genome duplication. (vandepeerlab.org)
  • ORCAE is an online genome annotation resource offering users the necessary tools and information to validate and correct gene annotations. (vandepeerlab.org)
  • The occurrence of multiple recent eukaryotic transfers in the food environment provides strong evidence for the importance of this understudied and probably underestimated phenomenon in eukaryotes. (nature.com)
  • However, over the last 20 years or so, a number of cases of gene transfer in eukaryotes have been described. (nature.com)
  • Despite these examples, the lack of specific evolutionary trends in reported cases of lateral gene transfer in eukaryotes has led to the view of ancient, sporadic and isolated events with relatively little global impact on eukaryotic kingdoms, rather than a more frequently and widely occurring phenomenon. (nature.com)
  • The mitochondrial gene content is highly variable across eukaryotes. (biomedcentral.com)
  • Guy works with comparative genomics, phylogenomics and genome assembly with an interest in the evolutionary relationships of eukaryotes and the cellular & genomic innovations of the diversity of eukaryotic cells. (evomics.org)
  • We successfully employed deep sequencing RNA-Seq data in combination with an elaborate bioinformatics strategy in order to identify novel genes, incorrect gene models and mechanisms of transcript processing in the corn anthracnose fungus C. graminicola . (biomedcentral.com)
  • These modules allow students to utilize cutting-edge bioinformatics algorithms to explore proto-genes via web based tools without requiring any coding experience. (yeastorfanproject.com)
  • Measures to combat fungal infections require detailed knowledge of the fungal infection biology. (biomedcentral.com)
  • My major goal is to gain a better understanding of the factors leading to susceptibility to opportunistic fungal infections and to identify crucial events occurring during infection development, which could potentially allow identification of novel clinical management or therapeutic strategies for these infections. (abdn.ac.uk)
  • Patients with prolonged neutropenia after hematopoietic stem cell transplantation or chemotherapy and patients receiving broad-spectrum antibiotics and high doses of corticosteroids are predisposed to fungal infections. (msdmanuals.com)
  • All relevant materials for patients and clinicians concerning the multistate outbreak of fungal meningitis and other infections are located on this page. (cdc.gov)
  • The numbers reported here do not reflect all cases of fungal meningitis, joint infections, and epidural abscesses because laboratory methods are not sensitive enough to detect all positive samples. (cdc.gov)
  • Many patients with potential fungal infections will have a negative laboratory result. (cdc.gov)
  • In biology, a marker gene may have several meanings. (wikipedia.org)
  • In nuclear biology and molecular biology, a marker gene is a gene used to determine if a nucleic acid sequence has been successfully inserted into an organism's DNA. (wikipedia.org)
  • In a synergistic educational activity designed to promote literacy in evolutionary biology, we are developing a novel "adopt a proto-gene" initiative whereby students and educators working with undergraduates can characterize individual proto-genes at their home institution. (yeastorfanproject.com)
  • Aside from their evolutionary potential, how do proto-genes impact cell biology? (yeastorfanproject.com)
  • The lab is structured around a transversal research theme (orphan gene dynamics) and three study domains: plant genomics, fungal genomics and marine plankton metagenomics. (cea.fr)
  • In: Comparative genomics: Empirical and analytical approaches to gene order dynamics, map alignment and the evolution of gene families (D.Sankoff and J.H. Nadeau, eds. (umontreal.ca)
  • 2001. Population genomics: gene expression in a vineyard yeast from Tuscany. (berkeley.edu)
  • The identification and functional characterization of 24 genes that are involved in iron homeostasis in A. fumigatus and/or Aspergillus nidulans , respectively, revealed significant insights into iron metabolism and its regulation (Table 1 ). (frontiersin.org)
  • 2015 ) Development of the CRISPR/Cas9 system for targeted gene disruption in Aspergillus fumigatus. (academictree.org)
  • 2013 ) The fungal pathogen Aspergillus fumigatus regulates growth, metabolism, and stress resistance in response to light. (academictree.org)
  • Down-regulation of Spds in the mutant altered overall nitrogen metabolism and significantly reduced fungal growth, pathogenicity, and the production of aflatoxins during maize seed infection. (usda.gov)
  • RNA-seq based transcriptome analysis highlighted that Cfhos2 regulates secondary metabolism-related virulence genes during infection. (biomedcentral.com)
  • To prosper in diverse ecological niches, Aspergilli have evolved numerous mechanisms for adaptive gene regulation, some of which are also crucial for mammalian infection. (manchester.ac.uk)
  • Treatment of the roots with bacteria prior to infection with V. dahliae resulted in a significant reduction of fungal root colonization. (frontiersin.org)
  • Since the start of the outbreak in September 2012, CDC and State health laboratories have tested tissue and fluid samples from patients with probable or confirmed fungal infection. (cdc.gov)
  • As of March 11, 2013, Exserohilum rostratum has been identified as the predominant fungal infection in this outbreak. (cdc.gov)
  • In fact, a major project replaced almost 500 individual fungal genes with their human equivalents and nearly half of the replacements resulted in the yeast being "just fine" . (databasefootball.com)
  • This was the fungus used in the above-mentioned experiment where researchers replaced yeast genes with human genes . (databasefootball.com)
  • In contrast to other Penicillia, though, P. marneffei grows as a yeast-like entity (arthroconidium) when found in diseased tissue or cultivated at 37 °C. Studies in our laboratory have focused on the differential gene expression between the mould and arthroconidial phases. (bioone.org)
  • Innovation of mitochondria-localized proteins occurred widely during fungal transitions, indicating their previously unrecognized importance. (biomedcentral.com)
  • Histones are conserved eukaryotic proteins that pack DNA into a compact structure called chromatin. (biomedcentral.com)
  • Typical triploblastic animal mtDNAs contain genes that encode the large and small subunit ribosomal RNAs, 22 transfer RNAs (tRNAs), and 13 proteins that are all components of the oxidative phosphorylation process: ATPase subunits 6 and 8 (ATP6 and 8), cytochrome b (Cyt b), cytochrome c oxidase subunits 1-3 (Cox1-3) and NADH dehydrogenase subunits 1-6 and 4L (ND1-6 and 4L). (biomedcentral.com)
  • Biosynthesis of spermidine (Spd) is critical for cell growth as it is required for hypusination-mediated activation of eukaryotic initiation (translational) factor 5A (eIF5A). (usda.gov)
  • the tri6 gene, encoding a zinc finger protein involved in the regulation of trichothecene biosynthesis, from Fusarium sporotrichioides (Proctor et al. (justia.com)
  • We also find that prokaryote-derived horizontal gene transfer provided a small source of evolutionary novelty with such genes involved in key metabolic pathways. (biomedcentral.com)
  • Detecting Horizontal Gene Transfer between Closely Related Taxa. (cdc.gov)
  • Reduced translation initiation correlated with phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF2alpha) in wild-type cells. (ox.ac.uk)
  • He is interested in the modeling, measurement, and analysis of population genetic variation in global gene expression in order to reveal the extent of variation in regulation of gene expression in natural populations. (berkeley.edu)
  • Antimicrobial susceptibility, virulence gene profiles and molecular subtypes of Salmonella Newport isolated from humans and other sources. (cdc.gov)
  • A screenable marker will make cells containing the gene look different. (wikipedia.org)
  • Fungal cells are similar to human cells in that they have nuclei and other organelles to process energy, but lack chlorophyll or chloroplasts (the photosynthetic structures) as found in plants. (databasefootball.com)
  • In the current study we evaluated the importance of a polyamine (nitrogenous compound) biosynthetic gene, spermidine synthase (Spds) that is required to produce the polyamine spermidine (Spd), which is critical for living cells to survive. (usda.gov)
  • The present invention also relates to mutants of filamentous fungal cells and methods for obtaining the mutant cells. (justia.com)
  • The present invention further relates to mutants cells comprising a marker-free modification of a gene, and methods for obtaining and using such mutant cells. (justia.com)
  • The present invention relates to methods for producing heterologous polypeptides in trichothecene-deficient filamentous fungal mutant cells. (justia.com)
  • This is due to the localization of these molecular sensors at the periphery of the fungal cell, and to the prevalence of small molecules and licensed drugs which target receptor-mediated signaling in higher eukaryotic cells. (manchester.ac.uk)
  • I have also used microarray analyses to compare gene expression in known virulent and attenuated C. albicans clinical isolates, demonstrating that there are few differences under laboratory conditions (Eukaryotic Cell, 2009). (abdn.ac.uk)
  • Comparative analyses of its 38.5-megabase genome, which encodes 13,210 predicted genes, reveal the species's unique wood-degrading machinery. (nature.com)
  • A more detailed analyses on bacterial-fungal co-cultivation in narrow interaction channels of microfluidic devices revealed that the strongest inhibitory potential was found for Pseudomonas protegens CHA0, with its inhibitory potential depending on the presence of the GacS/GacA system controlling several bacterial metabolites. (frontiersin.org)
  • Many of the genes whose expression differs during mould-to-arthrocondium transition are related to energy metabolism. (bioone.org)
  • Histone-modifying enzymes, which regulate eukaryotic chromatin conformation and gene expression, are key epigenetic factors controlling fungal development, virulence, and secondary metabolism. (biomedcentral.com)
  • Eukaryotic fungal and animal clocks comprise transcription-translation-based feedback loops that control rhythmic transcription of a substantial fraction of these transcriptomes, yielding the changes in protein abundance that mediate circadian regulation of physiology and metabolism: Understanding circadian control of gene expression is key to understanding eukaryotic, including fungal, physiology. (dartmouth.edu)
  • An annotated genomic sequence of the corn anthracnose fungus Colletotrichum graminicola has been published previously, but correct identification of gene models by means of automated gene annotation remains a challenge. (biomedcentral.com)
  • In addition, the terminal regions of the chromosomes tend to house genes with predicted roles in ecological adaptation. (uky.edu)
  • All of the virulence-associated genes are transcriptionally upregulated during iron starvation and encode functions that are important for survival during iron starvation, which emphasizes the crucial role of adaptation to iron starvation in virulence. (frontiersin.org)
  • One-third of the 471 genes predicted to encode transcription factors are differentially expressed during sexual development of S. commune . (nature.com)
  • Despite a disparity in gene content, all mtDNAs encode at least two components of the mitochondrial electron transport chain, including cytochrome c oxidase I (Cox1). (biomedcentral.com)
  • In some mtDNAs (e.g., nematodes and annelids), all genes are transcribed in the same direction, whereas, in others, both strands encode genes. (biomedcentral.com)
  • In particular, there are two sub-types of these marker genes: a selectable marker and a marker for screening. (wikipedia.org)
  • One is to focus on specific marker genes for taxonomic identification only . (seqomics.hu)
  • The most commonly used molecular approach for exploring microbial diversity is based on the PCR amplification and sequencing of genes encoding small subunit ribosomal RNA (16S rRNA) directly from environmental sources [ 16 ]. (biomedcentral.com)
  • For this so-called targeted amplicon approach , the ribosomal small subunit RNA ( 16S / 18S rRNA ) gene has emerged as the most used marker. (seqomics.hu)
  • 2006. Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii. (berkeley.edu)
  • Disruption of the Spds gene in A. flavus halted growth and required exogenous supply of Spd for the fungus to grow. (usda.gov)
  • A better understanding of gene expression during morphogenesis in P. marneffei may help detect unique target sites or cellular processes that can be exploited in the development of antifungal agents or immunomodulation therapies. (bioone.org)
  • Moreover, this strengthens evidence for mitochondrial genes coded according to an overlapping genetic code. (biomedcentral.com)
  • The mitochondrial genes are arranged compactly and generally have no introns and few intergenic nucleotides. (biomedcentral.com)
  • The number of mitochondrial protein genes is believed to vary from 3 to 67, while the tRNA gene content varies from 0 to 27 [ 2 ]. (biomedcentral.com)
  • Mitochondrial and eukaryotic origins: a critical review. (umontreal.ca)
  • Analysis of Clock-Regulated Genes in Neurospora Reveals Widespread Pos" by Jennifer M. M. Hurley, Arko Dasgupta et al. (dartmouth.edu)
  • Indeed, the isolation of clock-controlled genes (ccgs) was pioneered in Neurospora where circadian output begins with binding of the core circadian transcription factor WCC to a subset of ccg promoters, including those of many transcription factors. (dartmouth.edu)
  • High temporal resolution (2-h) sampling over 48 h using RNA sequencing (RNA-Seq) identified circadianly expressed genes in Neurospora, revealing that from ∼10% to as much 40% of the transcriptome can be expressed under circadian control. (dartmouth.edu)
  • Some proto-genes are occasionally retained by selection and become de novo genes, but most eventually return to a non-genic state. (yeastorfanproject.com)
  • Oxford Nanopore sequencing, hybrid error correction, and de novo assembly of a eukaryotic genome. (cdc.gov)
  • Two other major changes occurred during this transition: (1) all stages of fungal life cycles from this evolutionary point on have true cell walls and (2) the spindle pole body acts as a microtubule-organizing center for mitotic and meiotic nuclear division [ 11 ]. (biomedcentral.com)
  • [10] [11] A cell that switches to the biofilm mode of growth undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated . (wikipedia.org)
  • 2017 ) Circadian Clearance of a Fungal Pathogen from the Lung Is Not Based on Cell-intrinsic Macrophage Rhythms. (academictree.org)
  • Fungal dimorphism involves extensive changes in the cell physiology and morphology in response to external signals, producing drastic alterations in the cell wall structure and synthesis, whose growth pattern changes from isodiametric (spherical) to polarized or vice versa. (benthamscience.com)
  • It is the only mushroom-forming fungus for which genes have been inactivated by homologous recombination. (nature.com)
  • CDC's Fungus Reference Laboratory has the capacity and technology to examine fungal isolates under the microscope and to confirm their identification using DNA sequencing methods. (cdc.gov)
  • Therefore, Zcf29p regulates stress response probably through its control of other genes not tested in our study. (ncl.edu.tw)
  • 2002) FEBS Lett, 519: 147-152) and to regulate a spectrum of genes which suppress angiogenesis (Abdollahi et al. (justia.com)
  • 2002. Bayesian analysis of gene expression levels: statistical quantification of relative mRNA level across multiple strains or treatments. (berkeley.edu)
  • The bacterial lacZ gene encodes a beta-galactosidase enzyme. (wikipedia.org)
  • This allowed us to revise and unify the fungal CHS classification and to study the evolutionary history of the CHS multigenic family. (biomedcentral.com)
  • It also highlights the importance of HGT in the evolutionary history of CHS and describes bacterial chs genes for the first time. (biomedcentral.com)
  • Targeted integration by homologous recombination enables in-situ tagging and replacement of genes in the marine microeukaryote Diplonema papillatum . (umontreal.ca)
  • Green fluorescent protein as a marker for gene expression. (wikipedia.org)
  • 2005. An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognised in the host cytoplasm . (hutton.ac.uk)
  • 2012 ) Protein kinase A and fungal virulence: a sinister side to a conserved nutrient sensing pathway. (academictree.org)
  • The stress-activated protein kinase (SAPK) pathway plays a central role in coordinating gene expression in response to diverse environmental stress stimuli. (ox.ac.uk)
  • Mycofactories comprise a substantial share of significant current research in the area of fungal biotechnology, and constitutes an effort to compile high level research in this domain. (benthamscience.com)
  • The mission of our laboratory is two-fold: (1) to identify the fungal pathways. (uc.edu)
  • It is a culture-independent tool for studying bacterial, viral, fungal or eukaryotic communities and can be divided in two main categories . (seqomics.hu)
  • A positionally conserved ORF has been found on the complementary strand of the cox1 genes of both eukaryotic mitochondria (protist, plant, fungal and animal) and alpha-proteobacteria. (biomedcentral.com)
  • In: Plant Mitochondria: From Gene to Function. (umontreal.ca)
  • In addition, temperature increase caused by global warming might exacerbate the effects of fungal plant disease ( Siebold and von Tiedemann, 2013 ). (frontiersin.org)
  • Current evidence has been limited to mainly cross-sectional studies using 16S rRNA gene sequencing, attempting to answer the question 'who is there? (bmj.com)
  • Further, with advancing technologies, microbiome studies are shifting beyond the examination of the 16S rRNA gene, to include whole metagenome and metatranscriptome sequencing, as well as metabolome characterisation. (bmj.com)
  • Inactivation of Spds significantly reduced mycelial growth and sporulation in vitro and addition of exogenous Spd was required to restore fungal growth and sporulation. (usda.gov)
  • In metagenomics and phylogenetics, a marker gene is an orthologous gene group which can be used to delineate between taxonomic lineages. (wikipedia.org)
  • Rates of Lateral Gene Transfer in Prokaryotes: High but Why? (cdc.gov)
  • Whether a placement of single genes in the proper chromosomal context, stacking a number of genes in the same chromosomal locus, rearrangement of existing chromosomal elements, or a global reconfiguration of the chromosomal structures is contemplated, the new genetic tools being developed provide technical capabilities to achieve goals that were only theoretical not long ago. (eurekaselect.com)
  • 2003. Population genetic variation in genome-wide gene expression in wine yeasts. (berkeley.edu)
  • Sets of eukaryotic transcripts can be analyzed by GeneMarkS-T . (gatech.edu)
  • Genes required for degradation of and growth on the carbon source pectin were down-regulated, whereas transcripts involved in redox processes were up-regulated. (frontiersin.org)
  • RNA-Seq offers the potential for substantially improved gene annotations and for the identification of posttranscriptional RNA modifications, such as alternative splicing and RNA editing. (biomedcentral.com)
  • I am having a hard time understanding how I can turn my gene predictions and annotations into a visual. (biostars.org)
  • A family of gene prediction programs developed at Georgia Institute of Technology , Atlanta, Georgia, USA. (gatech.edu)
  • Telomeres are the sequences that form the ends of eukaryotic chromosomes and are essential structures that confer genome stability and guide chromosome behavior. (uky.edu)
  • Other genes in the trichothecene biosynthetic pathway have been cloned including the tri3 gene, encoding a 15-O-acetyltransferase, from Fusarium sporotrichioides (McCormick et al. (justia.com)