Etiology genetic predisposition to disease. Medical search. Frequent questions

The pathogenesis of anti-glomerular basement membrane (anti-GBM) disease (Goodpasture disease) is linked to the presence of autoantibodies that react with the alveolus in the lung and the basement membrane of the glomerulus in the kidney. (medscape.com)
Genetic and environmental influences are involved in the pathogenesis. (medscape.com)
Although the disease more commonly affects some of the more darkly pigmented ethnic groups-including people of Asian, Hispanic, Native American, and Middle Eastern ancestry-and is uncommon among whites, VKH syndrome is also rare among sub-Saharan Africans, suggesting that additional factors, other than skin pigmentation, are important in its pathogenesis. (aao.org)
The precise etiology and pathogenesis of VKH syndrome are unknown, but current clinical and experimental evidence suggests a cell-mediated autoimmune process driven by T lymphocytes directed against self-antigens associated with melanocytes of all organ systems in genetically susceptible individuals. (aao.org)
Aetiology vs. Pathogenesis: What's the Difference? (difference.wiki)
Aetiology studies the causes or origins of diseases, while pathogenesis investigates the development and effects of diseases. (difference.wiki)
Aetiology and pathogenesis are terms used in medical science to study diseases. (difference.wiki)
Pathogenesis, on the other hand, delves into the mechanisms and processes by which a disease develops and progresses. (difference.wiki)
In contrast, pathogenesis explores the biological or molecular mechanisms that lead to the development of pathological conditions or diseases. (difference.wiki)
While aetiology provides insights into the 'why' and 'how' of disease occurrence, revealing the reasons behind the existence of diseases, pathogenesis offers an understanding of 'what' happens during the disease process. (difference.wiki)
Pathogenesis maps the progress of diseases, analyzing how they evolve and affect the body, allowing for the study of the complex interactions between a disease's causal agent and the host. (difference.wiki)
Pathogenesis, by understanding the development of diseases, facilitates the formulation of treatment approaches. (difference.wiki)
In summary, aetiology and pathogenesis are integral components of medical research. (difference.wiki)
Aetiology elucidates the origins and causes of diseases, paving the way for preventive measures, while pathogenesis explains the development and progression of diseases, forming the basis for therapeutic interventions. (difference.wiki)
Pathogenesis maps the progress and effects of diseases on the body. (difference.wiki)
Research on the pathogenesis of heart disease has led to advances in treatment options. (difference.wiki)
OBJECTIVE: Kawasaki disease (KD) can lead to permanent damage to coronary structures, the pathogenesis of which remains unknown. (bvsalud.org)

Here, we review the current knowledge of the effects of the pathogenic mutations linked to genetic CJD and fatal familial insomnia on the prion protein metabolism and physicochemical properties, the disease phenotype and the strain characteristics. (nih.gov)
However, despite such mutations being implicated in a combined total of approximately 50% of familial melanoma cases, the underlying genetic basis is unexplained for the remainder of high-density melanoma families. (nih.gov)
These associations between melanoma and other cancers hint at the possibility of common pathways for oncogenesis, and better knowledge of these pathways may improve understanding of the genetic basis underpinning familial melanoma. (nih.gov)
Molecular genetic etiology by whole exome sequence analysis in cases with familial type 1 diabetes mellitus without HLA haplotype predisposition or incomplete predisposition. (cdc.gov)

Eosinophilic cystitis, a rare condition, can be associated with allergic and autoimmune diseases such as lupus, parasitic infection, and systemic peripheral eosinophilia, such as in idiopathic hypereosinophilic syndrome . (medscape.com)
Autoimmune diseases are a group of disorders characterized by an aberrant immune response, wherein the body's immune system mistakenly attacks healthy cells and tissues. (alliedacademies.org)
This article provides an overview of the dermatological manifestations seen in autoimmune diseases, highlighting their clinical features and significance. (alliedacademies.org)
Pemphigus comprises a group of blistering autoimmune diseases affecting the skin and mucous membranes. (alliedacademies.org)
In addition to discussing the specific dermatological manifestations of autoimmune diseases, it is important to note that these manifestations can vary in severity and presentation among individuals. (alliedacademies.org)
It is worth mentioning that autoimmune diseases often have a multifactorial etiology, involving genetic predisposition, environmental triggers, and dysregulation of the immune system. (alliedacademies.org)
The precise mechanisms underlying the development of dermatological manifestations in autoimmune diseases are not fully understood, but it is believed that immune-mediated inflammation and tissue damage play significant roles [ 4 ]. (alliedacademies.org)
A variety of factors significantly reduce the efficiency of our cells, resulting in chronic inflammation and chronic autoimmune diseases, including rheumatoid arthritis. (functionalmedsystem.com)
In general, the real causes of autoimmune diseases, such as Rheumatoid Arthritis, are the lack or insufficiency of enzymes, hormones and other key elements of metabolism. (functionalmedsystem.com)
SS is among the most common autoimmune diseases, along with systemic lupus erythematosus and progressive systemic sclerosis. (biomedcentral.com)
Relatives of people with Sjögren syndrome are at an increased risk of developing autoimmune diseases, although they are not necessarily more likely to develop Sjögren syndrome in particular. (medlineplus.gov)

Susceptibility for some families is due to mutation in one of the known high penetrance melanoma predisposition genes: CDKN2A, CDK4, BAP1, POT1, ACD, TERF2IP and TERT. (nih.gov)
Aside from the possibility of extremely rare mutations in a few additional high penetrance genes yet to be discovered, this suggests a likely polygenic component to susceptibility, and a unique level of personal melanoma risk influenced by multiple low-risk alleles and genetic modifiers. (nih.gov)
Genetic differences may alter susceptibility to asthma, as well as responsiveness to asthma medications. (medscape.com)
To identify susceptibility loci specific to ER-negative disease, we combined in a meta-analysis 3 genome-wide association studies of 4,193 ER-negative breast cancer cases and 35,194 controls with a series of 40 follow-up studies (6,514 cases and 41,455 controls), genotyped using a custom Illumina array, iCOGS, developed by the Collaborative Oncological Gene-environment Study (COGS). (ox.ac.uk)
The genetic variations that increase susceptibility may reduce the body's ability to turn off the immune response when it is no longer needed. (medlineplus.gov)

The fourth known etiology of PTB is pathobiological distention of the uterus due to polyhydramnios (too much amniotic fluid) and/or multiple gestation. (myadlm.org)

Subsequently meat, dairy products and water serve as key vehicles in the transmission of MAP infection to humans (from farm to fork) who have a genetic predisposition, thus leading to the development of CD. (wjgnet.com)
In humans, idiopathic ulcers are recognized increasingly, more associated with complications, more refractory to therapy, and probably reflective of the interplay of genetic predisposition, rapid gastric emptying, acid hypersecretion, defective defense mechanisms, and psychological stress. (vin.com)

Goodpasture's name has been used in a more specific clinical condition known as Goodpasture disease, which is the pulmonary renal syndrome specifically associated with anti-glomerular basement membrane (anti-GBM) antibodies. (medscape.com)
Despite this triad of clinical findings, patients with anti-GBM disease may present with a spectrum of conditions ranging from pulmonary hemorrhage with minimal or no renal involvement to full-blown renal failure with limited or no pulmonary involvement. (medscape.com)
On the basis of this clinical report, Goodpasture's name is often linked to the pulmonary renal syndrome of alveolar hemorrhage and necrotizing and proliferative glomerulonephritis, although vasculitis and not anti-GBM disease is believed to be the cause of the pulmonary renal syndrome in Goodpasture's original patient. (medscape.com)
Both CJD and fatal insomnia are fully transmissible diseases, a feature that led to the isolation and characterization of different strains of the agent or prion showing distinctive clinical and neuropathological features after transmission to syngenic animals. (nih.gov)
Cystitis describes a broad range of diseases with diverse etiology and pathologic mechanisms but with similar clinical presentations. (medscape.com)
The numerous clinical, pathologic, and genetic similarities between SO and VKH syndrome suggest that they share a similar immunopathogenesis, albeit with different triggering events and modes of sensitization. (aao.org)
The clinical features of VKH syndrome also vary depending on the stage of the disease. (aao.org)
It seeks to understand the sequence of events that occur from the initial contact with an agent causing disease to the ultimate clinical manifestations. (difference.wiki)
It affects around 55 million people, with over 300 million at risk of developing clinical symptoms of Alzheimer's disease in the coming years. (biocentury.com)
The recent positive clinical data from two new Alzheimer's disease treatments - Leqembi lecanemab from Eisai Co. Ltd. (Tokyo:4523) and Biogen Inc. (NASDAQ:BIIB), and donanemab from Eli Lilly and Co. (NYSE:LLY) - should be hugely welcome, as they promise to bring some measure of relief to early-stage patients and their families. (biocentury.com)
Nevertheless, the positive data from passive immunization with mAbs inspires genuine hope that combination therapies and active immunotherapies will be able to halt disease progression or prevent the emergence of clinical symptoms. (biocentury.com)
We can already identify people with genetic predisposition and even detect signatures of β-amyloid and tau pathologies in the brains of people many years before they display any clinical symptoms. (biocentury.com)
In this paper, we review the history, epidemiology, and clinical subtypes of LP. We also review the histopathologic aspects of the disease, differential diagnoses, immunopathogenesis, and the clinical and genetic correlations. (hindawi.com)
Oral LP (OLP) can be the sole clinical presentation of the disease or accompanied by cutaneous or other mucosal manifestations including the genital area, gastrointestinal tract, and eyes. (hindawi.com)
Furthermore, the diverse clinical presentation and the asymptomatic nature of the most common subtype of OLP make the disease an underdiagnosed health issue [ 16 ]. (hindawi.com)
Feline caudal stomatitis (FCS)-a clinical diagnosis of inflammation and proliferation of the gingiva and oral mucosa-is a very frustrating and poorly understood disease in cats. (todaysveterinarypractice.com)
The clinical sign that differentiates caudal stomatitis from periodontal disease is the presence of caudal inflammation (distal to the teeth) in cases of caudal stomatitis ( Figure 2 ). (todaysveterinarypractice.com)
The etiology and clinical behavior of ER-negative tumors are different from those of tumors expressing ER (ER positive), including differences in genetic predisposition. (ox.ac.uk)
Targeted Screening for Gaucher Disease in High Suspicion Patients and Clinical Profile of Screen Positives in a Large Pediatric Multispecialty Hospital. (cdc.gov)

The complex etiology of neurodegenerative disease has prompted studies on multiple mechanisms including genetic predisposition, brain biochemistry, immunological responses, and microbial insult. (canlyme.com)
The immunological background of the disease is still ambiguous and both innate and acquired immunity have been implicated as contributing to airway inflammation. (slu.se)
Endometriosis is a complex disease and its etiology is multifactorial, characterized by the presence of endometrial tissue outside the uterine cavity especially in the pelvic peritoneum and ovaries, involving genetic predisposition, environmental factors, anatomical, endocrine and immunological changes. (usp.br)

Involves studying biological and molecular mechanisms of diseases. (difference.wiki)
2. Identify highly penetrant host genetic variants and molecular pathways predisposing healthy pediatric or young adult patients to, or protecting them from, severe COVID-19 disease. (genomics.ae)
3. Characterize the functional consequences of candidate SARS-CoV-2 and/or host predisposition genetic variants on the molecular and cellular etiology of the disease. (genomics.ae)
Molecular characterization of early breast cancer onset to understand disease phenotypes in African patients. (cdc.gov)

Prostate cancer (PCa) is a multifactorial disease with an unclear etiology. (mdpi.com)
The etiology of this multifactorial disease remains shrouded, meaning a true cure might still be hard to imagine. (biocentury.com)

A combination of genetic predisposition with an infectious trigger is the most accepted hypothesis for the etiology. (towerhealth.org)
In the case of asthma, it is associated with a combination of genetic predisposition and environmental factors, such as exposure to allergens or irritants. (speedyresearchpapers.com)

Role of Genetic Predisposition, Cytokines, and Neuroendocrine Response in Development of Thyroid Autoimmunity. (routledge.com)

Human prion diseases are a group of rare neurodegenerative disorders characterized by the conversion of the constitutively expressed prion protein, PrP(C), into an abnormally aggregated isoform, called PrP(Sc). (nih.gov)
Prion diseases show the highest extent of phenotypic heterogeneity among neurodegenerative disorders and comprise three major disease entities with variable though overlapping phenotypic features: Creutzfeldt-Jakob disease (CJD), fatal insomnia and the Gerstmann-Sträussler-Scheinker syndrome. (nih.gov)
Next-generation diagnostic and therapeutic solutions are already in view, and we could soon have the knowledge and tools to move to the next level: preventing rather than treating Alzheimer's and other neurodegenerative diseases. (biocentury.com)

9. Centers for Disease Control and Prevention. (cdc.gov)
Statements herein are not, in any way, to be interpreted as promissary for inclusion in any ADHD research agenda setting nor are they ADHD policy statements by the Centers for Disease Control and Prevention, National Center for Environmental Health. (cdc.gov)

The aetiology of diabetes includes lifestyle, genetics, and environmental factors. (difference.wiki)
Exploring People's Knowledge of Genetics and Attitude towards Genetic Testing: A Cross-Sectional Study in a Population with a High Prevalence of Consanguinity. (cdc.gov)

While most people who develop a prion disease have no identifiable cause and a few acquire the disease through an identified source of infection, about 10-15% of patients are affected by a genetic form and carry either a point mutation or an insertion of octapeptide repeats in the prion protein gene. (nih.gov)
Although the etiology of KD remains unidentified, epidemiological features point to the role of infection and genetic predisposition. (jiaci.org)
Dyspnea Cor pulmonale Respiratory failure Pneumothorax Bronchiectasis: recurrent bouts of bronchitis Decreased quality of life and functional status Decreased independence due to difficulty breathing and increased oxygen demands resulting in fatigue Assistance with activities of daily living (ADLs) as disease progresses Pneumonia, overwhelming respiratory infection. (lifenurses.com)
Type I Diabetes is also known as juvenile onset diabetes or insulin dependent diabetes and it has an autoimmune origin that is very much related to genetic predisposition or other events (a common precipitant for this may be a viral or bacterial infection) that cause a production of antibodies that target the pancreatic cells responsible for making insulin (Beta cells) destroying them. (khanacademy.org)

Potential etiologies in human and non-human animals include specific Helicobacter infections, nonsteroidal anti-inflammatory drugs, parasitism, foreign body, regional ischemia from physiologic stressors like sepsis, chronic hepatic or renal disease, exogenous substances that alter gastroduodenal function, gastrin-secreting neoplasms, and idiopathic. (vin.com)

RAO, Recurrent airway obstruction, is a non-infectious airway disease of horses. (slu.se)
Explore the latest questions and answers in Emerging Infectious Diseases, and find Emerging Infectious Diseases experts. (researchgate.net)
What are the Early Warning Signs and Predictive Factors for Emerging Infectious Diseases? (researchgate.net)
It examines the various factors, like environmental, genetic, and infectious, that can lead to the occurrence of diseases. (difference.wiki)
Emerging Infectious Diseases is a publication of the U.S. Government. (cdc.gov)

With heterozygous genetic profile of 3 mutations he has a genetic predisposition for developing a thrombophilic disease which could be involved in the etiology of CTEPH. (actamedicamarisiensis.ro)

Overweight and obesity are known risk by women over their clothes) or loose gown factors for diabetes, coronary heart disease, and whether inside or outside home], and stroke, hypertension, gall bladder disease, exercise taken (defined as brisk walking at osteoarthritis, sleep apnoea, some forms of least half an hour per day or doing exercises cancer and infertility. (who.int)
Several etiologic factors have been suggested and include maternal diabetes, hypoperfusion, as well as a genetic predisposition (for example mutation in VANGL1 gene (1p13.1), CELSR1 (22q13.31) and, FUZ gene (19q13.33). (orpha.net)
Certain chronic illnesses are incurable due to genetic predisposition or an unknown aetiology, including Type 1 diabetes, multiple sclerosis, rheumatoid arthritis, and cystic fibrosis. (uyirorganic.online)
Other chronic diseases can occasionally arise due to risk factors that individuals can control, including Type 2 diabetes, kidney illness, specific lung ailments, and stroke. (uyirorganic.online)
The relationship between islet autoantibody status and the genetic risk of type 1 diabetes in adult-onset type 1 diabetes. (cdc.gov)

Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP. LP is a T-cell mediated immunologic disease but the responsible antigen remains unidentified. (hindawi.com)

[ 1 ] Significant genetic variation exists between and within racial and ethnic groups, but the issue is confounded by important coexisting economic, cultural, and environmental differences, including geography (place of birth). (medscape.com)

Facilitates the development of strategies to reduce the prevalence of diseases. (difference.wiki)
Studies indicate that the number of people with PBC at a given time (referred to as the prevalence of disease) ranges from 19 to 251 per million population in various countries. (emedicinehealth.com)
Asthma is a chronic disease of the airways, which is increasing its prevalence among teenagers recently. (bvsalud.org)

Identify the disease type (primary, secondary, or tertiary) for the respiratory disease. (speedyresearchpapers.com)
and usIng genetIc data to IdentIfy the etIology of human cancers. (who.int)

Onset between ages 21 and 40 years is sometimes called young or early-onset Parkinson disease. (msdmanuals.com)
Aetiology takes into account a multitude of factors that can be attributed to the onset of a disease. (difference.wiki)
It is an autoimmune disease, as its onset is triggered by a mistaken attack of the immune system against the cells of its own organism. (functionalmedsystem.com)

Rheumatoid Arthritis is characterized as a chronic idiopathic inflammatory disorder, of unexplained and multiple etiology. (functionalmedsystem.com)

Pathology of Vogt-Koyanagi-Harada disease. (aao.org)

Systemic arterial hypertension is the most important modifiable risk factor for all-cause morbidity and mortality worldwide and is associated with an increased risk of cardiovascular disease (CVD). (nature.com)
Fewer than half of those with hypertension are aware of their condition, and many others are aware but not treated or inadequately treated, although successful treatment of hypertension reduces the global burden of disease and mortality. (nature.com)
Figure 1: Association between systolic blood pressure and coronary heart disease mortality. (nature.com)
Obesity and overweight affect, worldwide, over 1.7 billion people and is associated with premature mortality, chronic diseases and increase in health costs. (bvsalud.org)

Parkinson disease is a slowly progressive, degenerative disorder characterized by resting tremor, stiffness (rigidity), slow and decreased movement (bradykinesia), and eventually gait and/or postural instability. (msdmanuals.com)
Panner's disease, an ostechondrosis of the capitellum, is a rare disorder that usually affects the dominant elbow in individuals younger than 10 years old. (aspetar.com)
LP (Greek "Leichen" = tree moss, Latin "planus" = flat, even) [ 2 ] was first explained in 1869 by Dr. Wilson as an inflammatory disorder of the stratified squamous epithelia with an unknown etiology. (hindawi.com)
Future genetic studies of SLI may be most effective if they use measures of underlying cognitive processes, rather than relying on conventional psychometric definitions of disorder. (ox.ac.uk)

Despite being one of the most studied diseases in gynecology, its etiology remains unclear and there are several current theories to explain it. (usp.br)

Although the majority of genetic alterations associated with melanoma development are somatic, the underlying presence of heritable melanoma risk genes is an important component of disease occurrence. (nih.gov)
In addition to conferring a risk of cutaneous melanoma, some 'melanoma' predisposition genes have been linked to other cancers, with cancer clustering observed in melanoma families at rates greater than expected by chance. (nih.gov)
Other medium to high penetrance melanoma predisposition genes have been associated with renal cell carcinoma (MITF, BAP1) and glioma (POT1). (nih.gov)
It is likely that 'melanoma' risk genes will impact on mutation screening and genetic counselling not only for melanoma but also a range of other cancers. (nih.gov)
The role of genes in the etiology of specific language impairment. (ox.ac.uk)

The aetiology of hypertension involves the complex interplay of environmental and pathophysiological factors that affect multiple systems, as well as genetic predisposition. (nature.com)

Risk factors for asthma include a family history of allergic disease, the presence of allergen-specific immunoglobulin E (IgE), viral respiratory illnesses , exposure to aeroallergens , cigarette smoke, obesity , and lower socioeconomic status. (medscape.com)
The etiology of ADHD is unknown and risk factors, aside from genetic predispositions, are under-studied, especially at the population level. (cdc.gov)
What are promising etiologies to focus on-genetic, environmental toxins, other environmental exposures, pre- or postnatal factors? (cdc.gov)
Cystic ovary disease or syndrome is commonly considered to be associated with negative energy balance and stress factors in high-milk-production dairy cows. (msdvetmanual.com)
Development of cancer depends on the exposure to risk factors and genetic predispositions. (powershow.com)
Aetiology determines the causal relationships and risk factors associated with diseases. (difference.wiki)
Recent studies have also considered the role of other contributing factors, such as genetic predisposition and familiarity. (medicomunicare.it)
Characterized as a chronic disease with a multifactorial etiology, environmental factors and a genetic predisposition appear to be the main cofactors 1 . (bvsalud.org)
Tobacco use, second-hand smoke exposure, poor nutrition, especially diet low in fruits and vegetables and heavy in sodium and saturated fats, absence of physical fitness, and extreme alcohol consumption are all risk factors for chronic diseases. (uyirorganic.online)
Environmental, genetic, and immunologic factors appear to play a role. (medscape.com)
Participants answered two questionnaires: one on risk factors for allergic diseases (EISL) and the other on asthma symptoms (ISAAC asthma module). (bvsalud.org)

Signs and symptoms are usually many and multiple tests are often required for the diagnosis and confirmation of this disease. (wjgnet.com)
Treatment for Chronic Obstructive Pulmonary Disease (COPD) is designed to relieve symptoms and prevent complications. (lifenurses.com)
Since each etiology is different, prediction of PTB in women with overlapping symptoms may be very challenging. (myadlm.org)
Unfortunately, this type of treatment approach, while it is effective for some, only covers the symptoms of the disease and helps to temporarily relieve the patient of pain. (functionalmedsystem.com)
The most common symptoms of the disease are pelvic pain , temporarily tamponable with analgesics, and infertility. (medicomunicare.it)
Chronic illnesses include disease-specific symptoms, but they can also cause symptoms that aren't evident, such as pain, exhaustion, and mood swings. (uyirorganic.online)
The following chronic diseases list of symptoms indicates the possible origins and indicators of stress. (uyirorganic.online)

The etiology of IBD is poorly understood. (medscape.com)

In conclusion, asthma is a prevalent respiratory disease that affects a substantial number of individuals and has a significant impact on society and the healthcare industry. (speedyresearchpapers.com)
Parkinson's Disease and Cerebral Palsy are two debilitating diseases that have a substantial impact on the lives of millions of individuals. (uyirorganic.online)
Knowledge of genetic test results among caregivers and individuals with spinal muscular atrophy. (cdc.gov)
Racial and ethnic variation in BRCA1 and BRCA2 genetic test results among individuals referred for genetic counseling at a large urban comprehensive cancer center. (cdc.gov)
Is there a 'pandemic effect' on individuals' willingness to take genetic tests? (cdc.gov)

31 percent have arthritis, and 29 percent have coronary heart disease. (uyirorganic.online)

It is a disease that affects 0.8 - 1% of population and occurs two to three times more often in women than men. (functionalmedsystem.com)
PBC is a disease that disproportionately affects women, with 10 women for every man having the disease. (emedicinehealth.com)
Lichen planus (LP) is a chronic inflammatory and immune mediated disease that affects the skin, nails, hair, and mucous membranes. (hindawi.com)
Chronic diseases list comprises chronic obstructive pulmonary disease (COPD), Alzheimer's disease, and dementia and affects approximately 11% of seniors. (uyirorganic.online)

In particular, Lyme disease is often associated with neurocognitive impairment with variable manifestations between patients. (canlyme.com)

The exact etiology of this self-limiting eruption is unknown. (towerhealth.org)
The etiology of this disease process is currently unknown. (todaysveterinarypractice.com)
The inheritance pattern of this predisposition is unknown. (medlineplus.gov)
Paget’s is a disease of unknown etiology in which there is cellular remodeling and bone deformity from breakdown and disorganized new bone formation. (cdc.gov)

The hosts may have a unique genetic defect allowing them to become infected with eukaryotic parasites, or, the putative parasite may have efficient strategies for suppressing the hosts immune response. (researchgate.net)
Nutritional deficiencies may lead to lowered immune functioning, which, in turn, inhibits the bodys ability to fight infections, eliminate foreign substances, and recover quickly from disease. (powershow.com)

Follicular cystic ovary disease may be defined by several observations. (msdvetmanual.com)
The incidence of cystic ovary disease increases with age. (msdvetmanual.com)
In animals that develop cystic ovary disease, ovulation fails to occur and the dominant follicle continues to enlarge. (msdvetmanual.com)
An important component of the etiology of cystic ovary disease is the failure of positive feedback of follicular estrogen on the hypothalamus via estrogen receptor alpha to release sufficient gonadotropin-releasing hormone (Gn-RH) during estrus to trigger a luteinizing hormone surge. (msdvetmanual.com)
Cystic Kidney Diseases That Require a Differential Diagnosis from Autosomal Dominant Polycystic Kidney Disease (ADPKD). (cdc.gov)

The etiology of breast cancer is not fully understood. (who.int)

Activation of the inflammatory system occurs in most patients with advanced heart failure, regardless of etiology, and contributes to the pathophysiological milieu and the progression of the disease. (intechopen.com)
The fear of physical disability and / or joint deformities has a catalytic effect on the individual's psychology, while at the same time it is complicating the progression of the disease. (functionalmedsystem.com)

AGA is a polygenic recessive disease with a genetic predisposition. (czkealor.com)
Integrating genome-wide polygenic risk scores and non-genetic risk to predict colorectal cancer diagnosis using UK Biobank data: population based cohort study. (cdc.gov)

These skin findings often precede or coincide with muscle weakness and can assist in early diagnosis and monitoring disease activity. (alliedacademies.org)
MRI is also helpful to provide definitive diagnosis in the early stage of the disease. (aspetar.com)
Clinically, accurate diagnosis and individual treatment for SS are often challenging due to the complexity of etiology and the diversity of manifestation among SS patients. (biomedcentral.com)
A 62 year-old caucasian male was admitted in our pulmonary hypertension expert center with initial diagnosis of pulmonary veno-occlusive disease for validation and specific treatment approach. (actamedicamarisiensis.ro)

Their findings indicate that the number of new cases of PBC over time (referred to as the incidence of disease) has increased steadily from 16 per million population in 1976 to 251 per million in 1994. (emedicinehealth.com)

The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. (hindawi.com)

Lewy bodies appear in a temporal sequence, and many experts believe that Parkinson disease is a relatively late development in a systemic synucleinopathy. (msdmanuals.com)
A genetic predisposition for the development of the disease is further supported by the strong association with HLA-DR4 among Japanese patients and with HLA-DR1 or HLA-DR4 among Hispanic patients from southern California. (aao.org)
Impaired functions, especially for years at a time, will diminish the bodys ability to fight off early development, slow disease progression, and recover from harsh elimination therapies. (powershow.com)
It enables the understanding of the stages and patterns of disease development and is crucial in designing therapeutic interventions. (difference.wiki)
Development and progression of diseases. (difference.wiki)
Primary diseases are characterized by their own distinct etiology, development, and progression. (speedyresearchpapers.com)
however, no associations between specific genetic changes and the development of Sjögren syndrome have been confirmed. (medlineplus.gov)

Anti-GBM autoantibodies that are present in the circulation of patients with anti-GBM disease cross the fenestrated endothelium in the glomerulus and bind with the underlying GBM, inducing renal injury. (medscape.com)
[ 3 ] In Western countries, the financial burden on patients ranges from $300 to $1,300 per patient year, increasing with more severe disease. (medscape.com)
more than half of all expenditures are attributed to the 10-20% of patients with the most severe disease. (medscape.com)
Because most COPD patients receive outpatient treatment, they need comprehensive patient teaching to help them comply with therapy and understand the nature of this chronic, progressive disease. (lifenurses.com)
There is evidence that the majority of patients have a genetic predisposition to developing the disease. (functionalmedsystem.com)
Many PIDD patients have a family history of immunodeficiency or associated autoimmune disease , but may not even be aware of it. (symptoma.com)
Introduction: In India, almost 150,000 women are diagnosed with breast cancer every year and almost half of patients expected to die of the disease. (who.int)
In India most of patients with breast cancer diagnosed with advanced stage of the disease. (who.int)
46 (23%) patients were diagnosed with LABC, and had undergone chemotherapy first for downstage of the disease. (who.int)

Research and select a respiratory disease that has a significant impact on society and the health care industry. (speedyresearchpapers.com)
Describe the respiratory disease you selected. (speedyresearchpapers.com)
Describe why the respiratory disease is classified as the disease type you identified. (speedyresearchpapers.com)
Describe what impact the respiratory disease you selected has on society as it relates to the business of health care and the use of resources. (speedyresearchpapers.com)
Asthma is a respiratory disease that has a significant impact on society and the healthcare industry. (speedyresearchpapers.com)
Asthma is classified as a chronic primary respiratory disease. (speedyresearchpapers.com)

In CSLs, this review suggests that perforating ulcerative gastroduodenitis in yearlings is a syndrome that does not have a common etiology in gastrointestinal parasitism, mixed or spiral bacteria, foreign bodies, apparent extra-gastrointestinal disease, or cancer. (vin.com)
Breast cancer is a common and frequently fatal disease, and the second ranking cause of cancer death in the Eastern Mediterranean Region. (who.int)
Progressive hearing loss is a common symptom of Paget’s disease, the result of the eighth cranial nerve being compressed by bony overgrowth or the small bones of the middle ear being disrupted. (cdc.gov)

These diseases can affect various organs and systems, including the skin. (alliedacademies.org)
Granulomatosis with Polyangiitis can affect virtually any site in the body, but it has a predisposition for certain organs. (hopkinsvasculitis.org)
Listed below are the organs commonly involved in Granulomatosis with Polyangiitis and the specific disease manifestation(s) in each organ. (hopkinsvasculitis.org)

Psychological Stress and Its Relationship to Cytokines and Inflammatory Diseases. (routledge.com)
Inflammatory cardiomyopathy can also occur in connection with autoimmune inflammatory diseases. (intechopen.com)

The incidence of different types of cystitis varies wildly by etiology and the affected patient population. (medscape.com)

The disease is characterized by periods of reversible obstruction and inflammation of the small airways caused by bronchospasm and accumulation of mucus and neutrophils in the airways. (slu.se)
Asthma is a chronic disease of the airways that can impose substantial morbidity for the individual and cost for the health care system. (bvsalud.org)

Parkinson disease is usually idiopathic. (msdmanuals.com)
Kawasaki disease (KD) is a form of idiopathic vasculitis frequently accompanied by coronary artery lesions, which involves endothelial dysfunction. (bvsalud.org)

Many research studies have highlighted the positive effects of natural flavonoids on chronic diseases, including PCa. (mdpi.com)
Things you most likely didn't know about Chronic diseases! (uyirorganic.online)
Chronic diseases have impacted the wellbeing and quality of life of a large number of persons worldwide. (uyirorganic.online)
Additionally, chronic diseases have been a significant driver of health care expenses, as well as a factor in labour habits, including absenteeism. (uyirorganic.online)
While numerous chronic diseases are prevalent and costly, they are also avoidable. (uyirorganic.online)
Several chronic diseases are associated with lifestyle decisions that you can alter. (uyirorganic.online)
Depression and heart problems , which afflict 14% of seniors, are among the Chronic diseases list. (uyirorganic.online)

Psoriasis is a complex, chronic, multifactorial, inflammatory disease that involves hyperproliferation of the keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate (see the image below). (medscape.com)

Endometriosis is an estrogen-dependent pelvic inflammatory disease characterized by implantation and growth of endometrial tissue (glands and stroma) outside the uterine cavity. (medicomunicare.it)

A Model for Understanding the Etiology of Major Depression and Chronic Fatigue Syndrome? (routledge.com)
Our lab's mission is to develop therapies for regenerating human tissues lost due to diseases or aging, and to build tissue engineered 3D models for understanding disease progression and informing drug discovery. (stanford.edu)
Understanding the aetiology of a disease is crucial for its prevention and treatment. (difference.wiki)

Anatomy8

Organisms6

Diseases61

Chemicals and Drugs39

Analytical, Diagnostic and Therapeutic Techniques and Equipment42

Psychiatry and Psychology11

Phenomena and Processes80

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena2

Humanities1

Information Science6

Named Groups9

Health Care30

Geographicals8

Pathogenesis17

Familial4

Autoimmune diseases11

Susceptibility5

Known etiology1

Humans2

Clinical19

Immunological3

Molecular4

Multifactorial disease2

Combination of genetic2

Autoimmunity1

Neurodegenerative3

Centers for Diseas2

Genetics2

Infection4

Neoplasms1

Infectious5

Mutations1

Diabetes5

Remains unidentified1

Differences1

Prevalence3

Identify2

Onset3

Rheumatoid1

Pathology1

Mortality4

Disorder4

Unclear1

Genes5

Interplay1

Factors11

Symptoms7

Poorly understood1

Individuals5

Coronary heart d1

Affects4

Manifestations1

Unknown4

Immune2

Cystic5

Understood1

Progression of the disease2

Polygenic2

Diagnosis4

Findings1

Variants1

Development7

Patients9

Respiratory6

Common3

Organs3

Inflammatory Diseases2

Incidence1

Airways2

Idiopathic2

Chronic diseases7

Involves1

Endometrial tissue1

Understanding3