• reactive
  • Although reactive oxygen species are thought to have a significant role in ethanol-induced hepatocellular damage, they may have a less important role in the inability of hepatocytes to replace dead or damaged cells. (mdpi.com)
  • Alcohol also induces the CYP2E1 enzyme, which metabolizes ethanol and other substances into more reactive toxins. (wikipedia.org)
  • presence of ethanol
  • Results: Cultures maintained in the presence of ethanol demonstrated a G2/M cell cycle arrest that was associated with a reduction in DNA content and increased levels of p-Cdc2 and p21, compared with cells cultured in its absence. (mdpi.com)
  • Studies demonstrate that the removal of this accumulated ethanol does not immediately restore fermentative activity, and they provide evidence that the decline in metabolic rate is due to physiological changes (including possible ethanol damage) rather than to the presence of ethanol. (wikipedia.org)
  • intermediate
  • By using static headspace-gas chromatography for liquid phase analysis, we identify acetaldehyde as a minor product and key intermediate in the electroreduction of CO to ethanol on OD-Cu electrodes. (osti.gov)
  • consume
  • When individuals with this allele consume ethanol chronically, a significant increased risk for upper alimentary tract and colorectal cancer is noted. (biomedcentral.com)
  • This is supported by research that determined the kinetic behavior of the ancestral ADH protein, which was found to be optimized to make ethanol, rather than consume it. (wikipedia.org)
  • pyruvate
  • Finally, pyruvate is converted to ethanol and CO2 in two steps, regenerating oxidized NAD+ needed for glycolysis: 1. (wikipedia.org)
  • carbon
  • Well-dispersed PtSn/C and PtSnO2/C catalysts with anatomic ratio of Pt:Sn (3:1) were deposited onto carbon using a modified alcohol-reduction process for electrochemical oxidation of ethanol. (sharif.edu)
  • In 1822, Georges-Simon Serullas added potassium metal to a solution of iodine in ethanol and water to form potassium formate and iodoform, called in the language of that time hydroiodide of carbon. (wikipedia.org)
  • metabolize
  • Background: Hepatocytes metabolize the vast majority of ingested ethanol. (mdpi.com)
  • Since ALDH2 assembles and functions as a tetramer and requires all four of its components to be active in order to metabolize acetaldehyde, heterozygotes have very little ALDH2 activity. (wikipedia.org)
  • The increase in rest energy expenditure has, according to some studies, been explained by indicating that the MEOS "expends" nine calories per gram of ethanol to metabolize versus 7 calories per gram of ethanol ingested. (wikipedia.org)
  • ingestion
  • Buccal cells were collected before ethanol ingestion. (separationsnow.com)
  • The initial symptoms of methanol exposure are usually less severe than the symptoms from the ingestion of a similar quantity of ethanol. (wikipedia.org)
  • First, methanol (whether it enters the body by ingestion, inhalation, or absorption through the skin) can be fatal due to its CNS depressant properties in the same manner as ethanol poisoning. (wikipedia.org)
  • chemical
  • Acetaldehyde (systematic name ethanal) is an organic chemical compound with the formula CH3CHO, sometimes abbreviated by chemists as MeCHO (Me = methyl). (wikipedia.org)
  • histamine
  • Earlier investigations with these plants have shown that they are effective in ameliorating ethanol-induced gastric ulceration and elevation of histamine and gastrin concentrations12-15. (redorbit.com)