GranulosaAndrogensOvariesReceptorsTestosteroneMajor naturally occurringFollicularProgesteroneAndrostenedioneEndogenousOvaryPostmenopausalEstroneEstradiolStimulatesTissuesAndrogenSynthesized in all vertebratesFollicleFolliclesGerm cellsSerumSteroidsFemalesLeydigHormonesMenopausePregnancyBindsDHEAProliferationReproductiveAdditionallyDecreasesThyroidHumansGeneHormoneCORTISOLMembraneUterusApoptosisProteinSertoli
Granulosa29
- More specifically, evidence indicates BPA-mediated disruption of STAR, CYP450scc, and HSD-3β in theca cells and CYP450 aromatase activity in granulosa cells. (desdaughter.com)
- In affected ovaries, oxygenation of follicular fluid is low, ultrastructural disturbances especially of mitochondria, occur in granulosa cells and oocytes, and considerable disturbances of meiosis occur. (biomedcentral.com)
- During the reproductive years most estradiol in women is produced by the granulosa cells of the ovaries by aromatization of testosterone from the theca cells, or conversion of estrone to estradiol. (the-medical-dictionary.com)
- This compound crosses the basal membrane into the surrounding granulosa cells , where it is converted to estrone or estradiol, either immediately or through testosterone. (wikidoc.org)
- The objective of this study was to determine the gene expression profiles of the androgen/androgen receptor (AR) and anti-Müllerian hormone (AMH)/ Sry-related high-mobility group box 9 (SOX9) pathways in granulosa-luteal cells from patients undergoing standard in vitro fertilization (IVF) with or without recombinant luteinizing hormone (rLH) therapy. (biomedcentral.com)
- Levels of reproductive hormones in the pre-ovulatory follicular fluid and the expression levels of LHR (luteinizing hormone receptor), AR, SOX9, AMH, AR-associated protein 54(ARA54)and ARA70 were determined in granulosa-luteal cells by real-time reverse-transcription PCR. (biomedcentral.com)
- We collected 35 an 70 granulosa cell samples from patients cycled with and without rLH supplementation, respectively. (biomedcentral.com)
- Moreover, granulosa-luteal cell mRNA levels of LHR, AR, AMH, and SOX9 were significantly higher in the rLH supplementation group relative to the group that did not receive rLH supplementation. (biomedcentral.com)
- In addition, we observed significant correlations between LHR and AR mRNA expression and among AR, AMH, and SOX9 mRNA expression in granulosa-luteal cells from patients undergoing standard IVF treatment. (biomedcentral.com)
- Increased expression of LHR, AR, AMH, and SOX9 is characteristic of granulosa-luteal cells from IVF/ intracytoplasmic sperm injection (ICSI) patients receiving rLH supplementation. (biomedcentral.com)
- Ovarian androgens are produced by thecal cells and exert their action in a paracrine fashion on granulosa cells. (biomedcentral.com)
- Granulosa cells produce androgens, which stimulates follicle maturation. (easynotecards.com)
- On day 1 of the cycle, growing follicles have both FSH and LH receptors on granulosa cells. (easynotecards.com)
- Follicle maturation is stimulated when FSH binds to theca cells and LH binds to granulosa cells. (easynotecards.com)
- This testosterone is passed over to the granulosa cells. (drfionand.com)
- The influence of pituitary FSH on the granulosa cells causes testosterone to turn into estradiol. (drfionand.com)
- These particles then pass between the cells composing the granulosa layer. (biomedcentral.com)
- The relatively narrow intercellular space of the primordial follicle allows ferritin and possibly other molecules of similar size to cross, whereas in the late stages of rapid follicular growth, the shape of granulosa cells must accommodate the increasing flow of egg yolk precursors that accumulate at the surface of the plasma membrane of the follicle [ 7 ]. (biomedcentral.com)
- In the ovaries, LH acts on theca and interstitial cells to produce progestins and androgens, and FSH acts on granulosa cells to stimulate aromatization of these precursor steroids to estrogen. (diseasesdic.com)
- The remaining cells in the follicle wall ( i.e. granulosa, membrana and periantral, theca, the theca interna and externa) develop into the corpus luteum. (glowm.com)
- LH activates theca cells to produce testosterone and the granulosa cells are usually secreted by FSH and there will be low estrogen. (tipsforwoman.com)
- Follicular phase , which is where rising FSH induces proliferation of granulosa cells , which surround the oocyte . (mrshum.com)
- Granulosa cells in turn secrete zona pellucida , which is a membrane immediately surrounding an oocyte . (mrshum.com)
- Granulosa cells can thus be viewed as the homolog to Sertoli cells . (mrshum.com)
- FSH also causes granulosa cells to secrete estrogen . (mrshum.com)
- LH induces proliferation of theca cells , which surround granulosa cells . (mrshum.com)
- The complex of a single oocyte (unfertilized egg ), granulosa cells and theca cells , is known as ovarian follicle . (mrshum.com)
- Other recent studies verified the presence of PAPP-A mRNA in granulosa cells of humans, monkeys, cattle, mice, and pigs. (bioone.org)
- Increases in the amount of PAPP-A mRNA in granulosa cells during follicular development occurs in some but not all species, indicating that other proteases or protease inhibitors may be involved in IGFBP degradation. (bioone.org)
Androgens9
- Quantitatively, estrogens circulate at lower levels than androgens in both men and women. (wikipedia.org)
- All of the different forms of estrogen are synthesized from androgens, specifically testosterone and androstenedione, by the enzyme aromatase. (wikipedia.org)
- Steroid hormones can be grouped into five groups by the receptors to which they bind: glucocorticoids, mineralocorticoids, androgens, estrogens, and progestogens. (absoluteastronomy.com)
- In many contexts, the two main classes of sex steroids are androgens and estrogens, of which the most important human derivatives are testosterone and estradiol, respectively. (illnesshacker.com)
- Other contexts will include progestogens as a third class of sex steroids, distinct from androgens and estrogens. (illnesshacker.com)
- In general, androgens are considered "male sex hormones", since they have masculinizing effects, while estrogens and progestogens are considered "female sex hormones" although all types are present in each sex, albeit at different levels. (illnesshacker.com)
- Theca cells produce estrogen, which is converted to the androgens that stimulate follicle maturation. (easynotecards.com)
- Secondary sexual characteristics result from high circulating levels of estrogens or androgens, without activation of the hypothalamic-pituitary axis. (msdmanuals.com)
- LH also induces theca cells to produce androgens (an example, being testosterone). (mrshum.com)
Ovaries5
- Estrogen is produced primarily by developing follicles in the ovaries, the corpus luteum , and the placenta . (wikidoc.org)
- Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) stimulate the production of estrogen in the ovaries . (wikidoc.org)
- Serum androgen and estrogen were measured and the morphological features of the ovaries were examined by light and electron microscopy in the offspring of each group. (biomedcentral.com)
- When it comes to the ovaries, the pituitary hormone LH causes the uptake of cholesterol into and the production of pregnenolone within the ovarian theca cells that is then turned into testosterone. (drfionand.com)
- COS was given to mice through the best route of administration, and the changes in ovarian and immune function were detected using assays of organ index, follicle counting, serum estrogen (E 2 ) and anti-Mullerian hormone (AMH) levels, and the expression of IL-2 and TNF-α in the ovaries. (biomedcentral.com)
Receptors9
- Once inside the cell, they bind to and activate estrogen receptors (ERs) which in turn modulate the expression of many genes. (wikipedia.org)
- Additionally, estrogens bind to and activate rapid-signaling membrane estrogen receptors (mERs), such as GPER (GPR30). (wikipedia.org)
- Two types of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and the estrogen G protein-coupled receptor GPR30 , which is a G protein-coupled. (absoluteastronomy.com)
- G protein-coupled receptors , also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors , comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal. (absoluteastronomy.com)
- Sex hormone steroids , also known as gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors. (illnesshacker.com)
- Experimental literature demonstrates BPA 's affinity for estrogen receptors and downstream effects on estrogen-responsive genes. (desdaughter.com)
- inside the cell, they interact with estrogen receptors . (wikidoc.org)
- The biological actions of raloxifene are largely mediated through binding to estrogen receptors. (drugcentral.org)
- Hormones are recognised by either cell surface receptors (modified amino acids, peptides, proteins) or cytoplasmic/nuclear receptors (steroids). (edu.au)
Testosterone6
- Estrogen, a steroid hormone, is derived from the androgenic precursors androstenedione and testosterone by means of aromatization. (medscape.com)
- The process of ovulation itself involves great change in the production of estradiol, testosterone and progesterone within the cells of the ovary in a cyclic pattern. (drfionand.com)
- The production of estrogen and at a lower magnitude testosterone by the theca of the growing follicle increases 2 to 3 weeks before the production of the first egg and contributes to the development of reproductive organs and the synthesis of egg constituents [ 1 - 6 ]. (biomedcentral.com)
- In the testes, LH stimulates Leydig cells to secrete testosterone, whereas FSH is necessary for tubular growth. (diseasesdic.com)
- In obese patients there is a lot of aromatase which converts testosterone into estrogen. (tipsforwoman.com)
- It starts in the seminiferous tubules of the testes , Leydig cells are stimulated by LH to produce the steroid hormone testosterone , which stimulate spermatogenesis . (mrshum.com)
Major naturally occurring2
- The four major naturally occurring estrogens are estrone (E1), estradiol (E2), estriol (E3), and estetrol (E4). (wikipedia.org)
- The three major naturally occurring estrogens in women are estradiol , estriol , and estrone . (wikidoc.org)
Follicular3
- This provides conditions for increased ceramide synthesis and follicular loss through ceramide-induced apoptosis is accelerated. (biomedcentral.com)
- Which of the following is TRUE of follicular estrogen synthesis? (easynotecards.com)
- During the course of folliculogenesis, growth is achieved by cell proliferation and formation of follicular fluid, whereas development involves cytodifferentiation of all the cells and tissues in the follicle. (glowm.com)
Progesterone7
- Estrogen therapy, with or without a progestogen (progesterone and progestin), has long been prescribed to treat menopausal symptoms. (medscape.com)
- Progesterone is only produced by the theca cells after ovulation has occurred until the ovarian corpus luteum cells degenerate. (drfionand.com)
- So Why Do Women's levels of Estrogen and Progesterone Drop with Stress, Then? (drfionand.com)
- There is a situation where stress will lower the production of estrogen and progesterone: Hypothalamic Amenorrhea. (drfionand.com)
- Patients also have irregular menses, due to high estrogen and lack of progesterone. (tipsforwoman.com)
- Luteal phase , where FSH and LH cause the remaining follicle (with its oocyte removed) to transform into the corpus luteum , which secretes progesterone and estrogen . (mrshum.com)
- Placenta secretes progesterone , estrogen , and HCG . (mrshum.com)
Androstenedione2
- In females, synthesis of estrogens starts in theca interna cells in the ovary, by the synthesis of androstenedione from cholesterol. (gracialatinasantiago.com)
- Theca cells are the sole ovarian site of synthesis of DHEA, which is both a precursor of androstenedione and an essential ligand for peroxisome proliferator-activated receptor alpha (PPARα), the key promoter of genes affecting fatty acid metabolism and fat transport and genes critical to mitochondrial function. (biomedcentral.com)
Endogenous5
- There are three major endogenous estrogens that have estrogenic hormonal activity: estrone (E1), estradiol (E2), and estriol (E3). (wikipedia.org)
- Additional data suggest that BPA reduces endogenous estrogen synthesis, likely by antagonizing ovarian enzyme activities involved in sex-steroid hormone synthesis. (desdaughter.com)
- which he continued to administer for 2 years, with a desire to enable conception of his wife not understanding oral contraceptive pills with their exogenous oestrogen, suppress endogenous oestrogen preventing ovulation to conceive, produce withdrawal bleeding, due to suppressed endogenous oestrogen-suppressed uterine development resulting in infantile uterus. (scirp.org)
- This persons contraception status increases thrombogenicity due to reduced endogenous oestrogen status secondary to germ cells destruction by contraception, over that her consumption of hormonal pills to postpone menstruation further decreases endogenous oestrogen, increased vulnerability for pulmonary thromboembolism. (scirp.org)
- Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands. (cmdm.tw)
Ovary5
- Only a few follicles in the human ovary survive to complete the cytodifferentiation process, with 99.9% dying by a programmed cell death mechanism called apoptosis. (glowm.com)
- Its essence is ovarian follicle depletion, and the resulting low estrogen levels in the ovary induce the occurrence and development of many other diseases [ 1 ]. (biomedcentral.com)
- It was found that ovoid cells in the epithelial layer of the ovary simultaneously expressed the germ cell specific marker MVH and the proliferation of cell marker BrdU using double-immunofluorescence staining. (biomedcentral.com)
- This discovery invalidated the "fixation theory of primordial follicle pool" and suggested for the first time the hypothesis that germ stem cells also exist in the ovary. (biomedcentral.com)
- Niikura [ 5 ] and others observed germ cells expressing Stra8 (stimulated by retinoic acid gene 8) in the ovarian surface epithelium, indicating that there may be germ cells with meiotic function in the ovary. (biomedcentral.com)
Postmenopausal3
- The metabolic effects of estrogen in postmenopausal women have been linked to the genetic polymorphism of the ER. (wikipedia.org)
- These secondary sources of estrogen are especially important in postmenopausal women. (wikidoc.org)
- The suppression of bone turnover markers was evident by months and persisted throughout the 36-month and 24-month observation periods.In 31-week, open-label, radiocalcium kinetics study, 33 early postmenopausal women were randomized to treatment with once-daily raloxifene hydrochloride tablets 60 mg, cyclic estrogen/progestin (0.625 mg conjugated estrogens daily with mg medroxyprogesterone acetate daily for the first weeks of each month [hormone therapy]), or no treatment. (drugcentral.org)
Estrone5
- During menopause, estrone is the predominant circulating estrogen and during pregnancy estriol is the predominant circulating estrogen in terms of serum levels. (wikipedia.org)
- However, during pregnancy this role shifts to estriol, and postmenopause, estrone becomes the primary form of estrogen in the body. (wikipedia.org)
- In order of potency, naturally occurring estrogens are 17 (beta)-estradiol (E2), estrone (E1), and estriol (E3). (medscape.com)
- Premarin , a commonly prescribed estrogenic drug, contains the steroidal estrogens equilin and equilenin , in addition to estrone sulfate. (wikidoc.org)
- Steroidogenesis , showing estrogen at bottom right as estrone and estradiol. (wikidoc.org)
Estradiol6
- Estradiol (E2) is the predominant estrogen during reproductive years both in terms of absolute serum levels as well as in terms of estrogenic activity. (wikipedia.org)
- Thus, estradiol is the most important estrogen in non-pregnant females who are between the menarche and menopause stages of life. (wikipedia.org)
- Particularly fat cells are active to convert precursors to estradiol, and will continue to do so even after the menopause. (the-medical-dictionary.com)
- Estradiol enters cells freely and interacts with a target cell receptor. (the-medical-dictionary.com)
- The mRNA interacts with ribosomes to produce specific proteins that express the effect of estradiol upon the target cell. (the-medical-dictionary.com)
- From menarche to menopause the primary estrogen is 17β-estradiol . (wikidoc.org)
Stimulates2
- Growing follicles produce estrogen, which further stimulates follicle maturation. (easynotecards.com)
- Estrogen stimulates a positive feedback loop , which increases production of LH . (mrshum.com)
Tissues4
- Structural Anabolic: Increases muscle mass and strength, speed of muscle regeneration, and bone density, increased sensitivity to exercise, protection against muscle damage, stronger collagen synthesis, increases the collagen content of connective tissues, tendons, and ligaments, but also decreases stiffness of tendons and ligaments (especially during menstruation). (wikipedia.org)
- Some estrogens are also produced in smaller amounts by other tissues such as the liver , adrenal glands , and the breasts . (wikidoc.org)
- Preclinical data demonstrate that raloxifene is an estrogen antagonist in uterine and breast tissues. (drugcentral.org)
- Ab-3 shows no reaction with a variety of normal tissues .CEA is not found in benign glands, stroma, or malignant prostatic cells. (samatashkhis.com)
Androgen3
- In females with normal fertility, pre-antral ovarian theca cells respond to stimulation by inhibin B to provide androgen-based support for the developing follicle. (biomedcentral.com)
- The effects of androgen and rLH treatments on AR and AMH expression levels were also tested in vitro using HO23 cells. (biomedcentral.com)
- Both prolactin and estrogen can affect adrenal androgen production. (medscape.com)
Synthesized in all vertebrates2
- Estrogens are synthesized in all vertebrates and some insects. (wikipedia.org)
- Estrogens are synthesized in all vertebrates as well as some insects. (absoluteastronomy.com)
Follicle3
- Reduced quality and accelerated follicle loss with female reproductive aging - does decline in theca dehydroepiandrosterone (DHEA) underlie the problem? (biomedcentral.com)
- With depletion of follicle numbers, inhibin B is reduced with consequent reduction in theca DHEA. (biomedcentral.com)
- Specialized hypothalamic neurons secrete pulses of gonadotropin-releasing hormone (GnRH) into the portal blood vessels, which acts on the gonadotrophs to cause a pulsatile release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which act on ovarian follicle cells to control folliculogenesis. (glowm.com)
Follicles1
- In some species (e.g., bovine), evidence indicates that decreases in IGFBP-4 and -5 levels in estrogen-dominant preovulatory follicles are likely due, in part, to increased protease activity, whereas lower levels of IGFBP-2 are not due to increased proteolysis. (bioone.org)
Germ cells4
- We have gained crucial insights into molecular factors and pathways of the cells generating either the supporting gonadal cells or germ cells of both sexes. (lidsen.com)
- An error during these developmental steps in females may lead to defective gonads, affecting the differentiation and/or function of the gonads and the development, differentiation, and maturity of the germ cells. (lidsen.com)
- are the organs that make gametes from germ cells . (mrshum.com)
- The organs which convert germ cells into gametes. (mrshum.com)
Serum3
- If previous treatment with estrogen resulted in hypertriglyceridemia, monitor serum triglycerides. (nih.gov)
- The transfer of the major egg yolk proteins such as Very Low Density Lipoproteins (VLDL) containing essentially apovitellenin and apolipoprotein-B, but also vitellogenins and some other plasma proteins from the blood such as serum albumin to the interstitial fluid of the thecae is possible due to the presence of broad discontinuities in the capillary endothelium. (biomedcentral.com)
- Clear indices of cell death-myocyte disruption, coagulative necrosis, elevation of cardiac proteins in serum-are present by 24 hours. (spiritsong.org)
Steroids2
- Unlike estrogens produced by mammals, these substances are not necessarily steroids . (wikidoc.org)
- Given that betaine has been suggested to boost greater levels of muscle protein synthesis and can decrease cortisol levels, it makes sense to put those doses on both ends of your intense training, androgenic vs estrogenic steroids. (tdtraktorist.ru)
Females1
- While estrogen levels are significantly lower in males than in females, estrogens nevertheless have important physiological roles in males. (wikipedia.org)
Leydig2
- e. occurs as the cells gradually travel between two closely attached Leydig cells. (easynotecards.com)
- Appearance of Leydig cells. (en-academic.com)
Hormones7
- Like all steroid hormones, estrogens readily diffuse across the cell membrane. (wikipedia.org)
- In addition to their role as natural hormones, estrogens are used as medications, for instance in menopausal hormone therapy, hormonal birth control and feminizing hormone therapy for transgender women, intersex people, and nonbinary people. (wikipedia.org)
- Like other steroid hormones, estrogen enters passively into the cell where it binds to and activates the estrogen receptor. (wikipedia.org)
- Insulin gene superfamily hormones regulate cell growth, metabolism, and tissue-specific functions. (phoenixbiotech.net)
- These hormones are made in the cell bodies and then transported to the axon terminals. (pharmaceuticalintelligence.com)
- The gland consists of numerous cell types, which specialize in making and releasing specific hormones. (pharmaceuticalintelligence.com)
- The blood carries the hormones to target cells that contain specific receptor proteins for the hormones, and which therefore can respond in a specific fashion to them. (50webs.org)
Menopause1
- Decreases in estrogen levels after oophorectomy or menopause lead to increases in bone resorption and accelerated bone loss. (drugcentral.org)
Pregnancy1
- Another estrogen called estetrol (E4) is produced only during pregnancy. (wikipedia.org)
Binds4
- The actions of estrogen are mediated by the estrogen receptor (ER), a dimeric nuclear protein that binds to DNA and controls gene expression. (wikipedia.org)
- The estrogen:ER complex binds to specific DNA sequences called a hormone response element to activate the transcription of target genes (in a study using an estrogen-dependent breast cancer cell line as model, 89 such genes were identified). (wikipedia.org)
- A gene in the sex-determining region of the short arm of the Y, now referred to as SRY , has been found to direct production of a protein which binds to DNA, inducing differentiation of cells derived from the genital ridges into testes. (en-academic.com)
- Atthetissuelevel,vitaminC is required for production of collagen and other compounds that comprise the intercellular matrix that binds cells together. (spiritsong.org)
DHEA1
- does decline in theca dehydroepiandrosterone (DHEA) underlie the problem? (biomedcentral.com)
Proliferation4
- The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line Cancer Cell International. (nottingham.ac.uk)
- The ovarian microenvironment affects the proliferation and differentiation of OGSCs, and immune cells and related cytokines are important components of the microenvironment. (biomedcentral.com)
- With increasing time, the fluorescence intensity of cells gradually increased, and the cytokines IL-2 and TNF-α significantly promoted the proliferation of OGSCs. (biomedcentral.com)
- It is worth noting that the proliferation and differentiation of stem cells cannot be separated from the surrounding microenvironment, and immune system related cells are an important part of the microenvironment of the OGSCs nest [ 14 ]. (biomedcentral.com)
Reproductive4
- Estrogen or oestrogen (see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. (wikipedia.org)
- Estrogens are among the wide range of endocrine-disrupting compounds (EDCs) and can cause health issues and reproductive disfunction in both wildlife and humans. (wikipedia.org)
- While estrogens are present in both men and women, they are usually present at significantly higher levels in women of reproductive age. (wikipedia.org)
- In males, estrogen regulates certain functions of the reproductive system important to the maturation of sperm and may be necessary for a healthy libido. (wikipedia.org)
Additionally1
- Additionally, we constructed gene-edited cell lines targeting these two amino acids, which completely restricted ALV-A entry without affecting Cbl uptake. (bvsalud.org)
Decreases1
- Soy protein peptic hydrolysate with bound phospholipids decreases micellar solubility and cholesterol absorption in rats and caco-2 cells. (cmdm.tw)
Thyroid1
- One study shows that the endocrine disrupting chemical bisphenol-A works in a fashion that is comparable to diethylstilboestrol at the cell and developmental level and research has clearly shown that many industrial chemicals can affect thyroid function. (hindustantimes.com)
Humans1
- Labelled the "female" hormone but also present in males it represents the major estrogen in humans. (the-medical-dictionary.com)
Gene6
- For information on therapeutic regulation of gene expression, see therapeutic gene modulation.Regulation of gene expression includes the processes that cells and viruses use to regulate the way that the information in genes is turned into gene products. (absoluteastronomy.com)
- Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. (absoluteastronomy.com)
- Finally, we constructed a Tva gene-edited cell line with L55R and W69L substitutions that could fully resist ALV-A entry, while Cbl uptake was not affected. (bvsalud.org)
- When the estrogen receptor has bound its ligand it can enter the nucleus of the target cell, and regulate gene transcription which leads to formation of messenger RNA. (the-medical-dictionary.com)
- The agonistic or antagonistic action of raloxifene depends on the extent of recruitment of coactivators and corepressors to estrogen receptor (ER) target gene promoters.Raloxifene appears to act as an estrogen agonist in bone. (drugcentral.org)
- Data suggest that a gene named KISS is important in the development of the LHRH-secreting cells. (diseasesdic.com)
Hormone3
- Hormone production happens differently in different endocrine glands(and *inside* of different cells). (drfionand.com)
- Human insulin is a peptide hormone produced by the beta-cells (β-cell) of the pancreas, and its release is dependent on glucose levels in the circulation, in addition amino acids, incretins and cholecystokinin also promote its release. (researchsquare.com)
- 1 The main function of insulin is to maintain glucose homeostasis, enabling glucose absorption and inhibiting hepatic gluconeogenesis, besides acting as an anabolic hormone that favors not only the absorption of amino acids and fatty acids, but also promotes cell growth and energy storage. (researchsquare.com)
CORTISOL1
- As aample, when cortisol is produced under stress or in the context of natural circadian rhythms, the pituitary gland releases ACTH and the adrenal zona faciculata cells take in cholesterol using special proteins and use it to make pregnenolone and convert it to cortisol. (drfionand.com)
Membrane2
- The cell membrane or plasma membrane is a biological membrane that separates the interior of all cells from the outside environment. (absoluteastronomy.com)
- The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances in and out of cells. (absoluteastronomy.com)
Uterus1
- These results are consistent with findings in clinical trials, which suggest that raloxifene hydrochloride lacks estrogen-like effects on the uterus and breast tissue. (drugcentral.org)
Apoptosis1
- The antibody is useful for studying the phenomenon of cell death by apoptosis as a pathogenic mechanism of numerous pathologies: nerve damage, neurodegenerative diseases, cardiovascular diseases, autoimmune diseases, AIDS and malignancies. (samatashkhis.com)
Protein2
- Protein synthesis and lipogenesis are highly stimulated in the liver at sexual maturity in hens (15 to 20 fold) to support the incorporation of 0.75 kg proteins and 1.5 kg of triglycerides into the yolk over a year of commercial production. (biomedcentral.com)
- BOB.1 from "B cell binding Octamer protein 1 "is a specific coactivator of transcription factors Oct-1 and Oct-2 of B lymphocytes. (samatashkhis.com)
Sertoli2
- c. requires participation of Sertoli cells. (easynotecards.com)
- Also within the seminiferous tubules , Sertoli cells are stimulated by FSH , which nurtures the stages of spermatogenesis . (mrshum.com)