• cytochrome P450 s
  • Erythromycin is an inhibitor of the cytochrome P450 system, which means it can have a rapid effect on levels of other drugs metabolised by this system, e.g., warfarin. (wikipedia.org)
  • Erythromycin is metabolized by enzymes of the cytochrome P450 system, in particular, by isozymes of the CYP3A superfamily, CYP3A. (wikipedia.org)
  • The erythromycin breath test (ERMBT) is a method used to measure metabolism (oxidation and elimination from the system) by a part of the cytochrome P450 system. (wikipedia.org)
  • motilin
  • Other functions of motilin include increasing the release of pancreatic polypeptide and somatostatin Erythromycin and related antibiotics act as non-peptide motilin agonists, and are sometimes used for their ability to stimulate gastrointestinal motility. (wikipedia.org)
  • Administration of a low dose of erythromycin will induce peristalsis, which provides additional support for the conclusion that motilin secretion triggers this pattern of gastrointestinal motility, rather than results from it. (wikipedia.org)
  • drugs
  • Erythromycin represents one of the many helpful drugs derived from nature-in this case, a drug used to kill or impede the growth of bacteria that actually is derived from a bacterial strain itself. (newworldencyclopedia.org)
  • Erythromycin belongs to a group of drugs known as macrolides . (newworldencyclopedia.org)
  • The activity of the CYP3A enzymes can be induced or inhibited by certain drugs (e.g. dexamethasone) which can cause it to affect the metabolism of many different drugs, e.g. erythromycin. (wikipedia.org)
  • If other CYP3A substrates - drugs that are broken down by CYP3A - such as simvastatin (Zocor), lovastatin (Mevacor), or atorvastatin (Lipitor)-are taken concomitantly with erythromycin, levels of the substrates increase, often causing adverse effects. (wikipedia.org)
  • Rats
  • There was no apparent effect on male or female fertility in rats fed erythromycin (base) at levels up to 0.25% of diet. (rxlist.com)
  • bacteria
  • Erythromycins are prescribed for a wide variety of infections caused by bacteria , including pneumonia, strep throat , bronchitis , ear infections, urinary tract infections, and tonsillitis (Ross-Flanigan 2004). (newworldencyclopedia.org)
  • Erythromycin can be used to treat bacteria responsible for causing infections of the skin and upper respiratory tract, including Streptococcus, Staphylococcus, Haemophilus and Corynebacterium genera. (wikipedia.org)
  • Oleandomycin can be employed to inhibit the activities of bacteria responsible for causing infections in the upper respiratory tract much like Erythromycin can. (wikipedia.org)
  • injection
  • Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of erythromycin injection in children. (mayoclinic.org)
  • However, elderly patients are more likely to have erythromycin-induced hearing loss, heart rhythm problems, and bleeding problems, and age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving erythromycin injection. (mayoclinic.org)