Epithelial cells bacterial adhesion. Medical search. Frequent questions

CD324 functions as a cell adhesion molecule involved in development, bacterial pathogenesis, and tumor invasion. (biolegend.com)
Once inside the host cells, it localizes under the point of bacterial attachment and interacts with the protein zonulin (ZO-1) and the junctional adhesion molecule (JAM) [ 4 ]. (nimml.org)
We have demonstrated that dusts of swine confinement facilities activate specific isoforms of an important cell-signaling molecule protein kinase C (PKC) that regulates inflammatory mediator release of airway epithelial cells and inflammatory cell interactions with the epithelial cells. (cdc.gov)

We determined the effect of vapour on oxidative stress-induced, PAFR-dependent pneumococcal adhesion to airway epithelial cells in vitro , and on pneumococcal colonisation in the mouse nasopharynx. (ersjournals.com)
The TNF-alpha-like domain triggers IL-8 production in cultured airway epithelial cells in a carbohydrate-independent manner, and is therefore proposed to play a role in the dysregulated proinflammatory response observed in B. cenocepacia lung infections. (qub.ac.uk)

For movement between different compartments within the cell, vesicles rely on the motor proteins myosin, kinesin (primarily anterograde transport) and dynein (primarily retrograde transport). (wikipedia.org)
CD324 binds to the α E β 7 integrin to mediate cell adhesion and also interacts with a number of intracellular proteins including including erbin, ezrin, caspase-3, caspase 8, β-catenin, presenilin 1, casein kinase II , as well as other extracellular proteins including the EGF receptor. (biolegend.com)
Only four Lactobacillus brevis strains express S-layer proteins, according to analyses of bacterial surface proteins using SDS-PAGE, 2D-PAGE, and PCR with specific primers for slp genes, while only three Lactobacillus plantarum strains were confirmed as bacteriocin producers using antibacterial activity assays and PCR with specific primers for genes encoding various bacteriocins. (alliedacademies.org)
Although the biological activities of Lactobacillus S-layer proteins are unknown, our findings show that they mediate bacterial adhesion to intestinal epithelial cells and extracellular matrix proteins, as well as regulate the immune response, both of which are significant probiotic features. (alliedacademies.org)
Here we employed 'plasma membrane profiling', a quantitative cell-surface proteomics technique, to identify host proteins whose cell-surface levels are altered during infection. (imperial.ac.uk)
Using this method, we quantified more than 1100 proteins, 280 of which showed altered cell-surface levels after exposure to EHEC. (imperial.ac.uk)
22 host proteins were significantly reduced on the surface of infected epithelial cells. (imperial.ac.uk)
Launch For all microorganisms well-timed and temporal legislation of gene appearance and its own translation to proteins level is essential for cell proliferation. (immune-source.com)
Bacterial surface proteins play determining roles in the NTHi-airways interplay, but their specific and relative contribution to colonization and infection of the respiratory tract has not been addressed comprehensively. (qub.ac.uk)
The aim of this project is to study the activity of milk fractions and proteins as inhibitors of bacterial and virus adhesion and proliferation, on epithelial intestinal cells. (unizar.es)
Isolation and characterization of milk fractions (whey, buttermilk and milk fat globule membraneenriched fraction) and isolated bioactive proteins (lactoferrin, lactadherin, mucins) derived from cow milk, and evaluation of their activity on the cell line Caco-2, used as an intestinal model (growth, oxidative stress, receptor expression). (unizar.es)
Evaluation of the activity of milk fractions and proteins as isolated and after technological treatments, on the cell line Caco-2 against infection by Gram-negative and Gram-positive bacteria, responsible for foodborne infections derived from dairy products. (unizar.es)
Evaluation of the activity of milk fractions and proteins as isolated and after technological treatments on the cell line Caco-2 after infection by rotavirus responsible for diarrhea in infants. (unizar.es)
Effect of milk fractions and proteins found to be the most active in Caco-2 cells, in murine models of intestinal disbiosis and inflammation, by determining intestinal motility, microbiota and expression of intestinal receptors and cytokines (1). (unizar.es)
One of the proteins translocated into the sponsor cells is the cytotoxin-associated gene A (CagA) protein which is definitely phosphorylated by sponsor kinases and interferes with key transmission transduction pathways [4]. (bio-cavagnou.info)
The interaction of LF with microbial surfaces-OMPs of Gram-negative bacteria in particular-has led to other antimicrobial mechanisms, such as the inhibition of microbial attachment to sub-epithelial matrix proteins and detachment of bacteria from mucosal surfaces. (ift.org)
Mutations in these proteins may alter the function of renal cilia, which enable tubular cells to sense flow rates. (msdmanuals.com)
This review summarizes some immunological factors involved in the development and control of this oral disease, such as: the participation of inflammatory cells in local inflammation, the synthesis of chemotaxis proteins with activation of the complement system and a range of antimicrobial peptides, such as defensins, cathelicidin and saposins. (bvsalud.org)

This plasmid encodes both bundle-forming pili (Bfp) that promote bacterial adherence to mammalian cells and are required for virulence ( 4 ) and a transcriptional activator, known as Per, that upregulates genes, such as eae , within a pathogenicity island termed the locus for enterocyte effacement (LEE) ( 5 ). (cdc.gov)
it furnishes a wide array of molecules that restrict microbes, such as antibodies, bactericidins, and inhibitors of bacterial adherence. (lu.se)
While investigating the effect of human milk on bacterial adherence to a human lung cancer cell line, we were surprised to discover that the milk killed the cells. (lu.se)
Effect of a berry polyphenolic fraction on biofilm formation, adherence properties and gene expression of Streptococcus mutans and its biocompatibility with oral epithelial cells. (cranberryinstitute.org)
Moreover in comparison to NrdR deletion cells overexpressing NrdR demonstrated significantly reduced adherence to individual epithelial cells reflecting reduced bacterial Fesoterodine fumarate (Toviaz) virulence. (immune-source.com)
In this study, bovine terminal rectal primary epithelial cells were used to examine the role of H7 flagella in epithelial adherence. (hw.ac.uk)

Atypical strains of enteropathogenic E. coli (EPEC) were the most frequently identified pathogens of all bacterial, viral, and parasitic agents in patients with gastroenteritis. (cdc.gov)
Genome analysis of C. concisus strains isolated from saliva samples has identified a bacterial marker that is associated with active Crohn's disease (one major form of IBD). (frontiersin.org)
Since invasive pneumococcal strains adhere to, and translocate across, respiratory tract epithelial cells, adhesion is a prerequisite for establishing pneumococcal disease [ 4 ]. (ersjournals.com)
it prevents the adhesion of certain bacterial strains ( E . coli ) to uro epithelial bladder cells. (green-infos.com)
The different cell strains pertain to disjunct regimes in a generic adhesion-migration trait space. (biorxiv.org)
Interaction of probiotic Lactobacillus and Bifidobacterium strains with human intestinal epithelial cells: adhesion properties, competition against enteropathogens and modulation of IL-8 production. (nature.com)

This different phenomenon has a major role in host-pathogen interactions, endotoxic shock in patients, invasion and infection of animals or plants, inter-species bacterial competition, quorum sensing, exocytosis, and other areas. (wikipedia.org)
induced during the infection of murine macrophage cells ( 15, 16). (researchgate.net)
The complement decay-accelerating factor CD55 exhibited the greatest reduction in cell surface levels during infection. (imperial.ac.uk)
This suggests that StcE alters host epithelial surfaces to depress neutrophil transepithelial migration during infection. (imperial.ac.uk)
This work is the first report of the global manipulation of the epithelial cell surface by a bacterial pathogen and illustrates the power of quantitative cell-surface proteomics in uncovering critical aspects of bacterial infection biology. (imperial.ac.uk)
Epidemiological studies suggest that inhalation of toxins increases the risk of airway bacterial infection. (ersjournals.com)
We employed isogenic single and double mutants of the ompP5 and hap genes generated in the pathogenic strain NTHi375 to evaluate P5 and Hap contribution to biofilm growth under continuous flow, to NTHi adhesion, and invasion/phagocytosis on nasal, pharyngeal, bronchial, alveolar cultured epithelial cells and alveolar macrophages, and to NTHi murine pulmonary infection. (qub.ac.uk)
We show that P5 is not required for bacterial biofilm growth, but it is involved in NTHi interplay with respiratory cells and in mouse lung infection. (qub.ac.uk)
We also show that Hap does not contribute to bacterial biofilm growth, and that its absence partially restores the deficiency in lung infection observed for the ΔompP5 mutant. (qub.ac.uk)
The major virulence factors associated with infections are the ability of microorganism to adhere to the tissue and initiate the interaction of bacterial cell with epithelial cells to cause infection. (interesjournals.org)
Sub MIC of antibiotics can exert their anti-virulent effects in different ways in such way to interfere with the ability of the microorganisms to approach the receptors on cell surfaces of host tissue and innate immunity system able to improve cell response to infection ( Ofek et al. (interesjournals.org)
Lectins and adhesins are involved in bacterial adhesion to host tissues and mucus during early steps of infection. (qub.ac.uk)
Available data in children indicate that probiotics seems to be efficacious for the prevention of antibiotic associated side-effects, and might be of help for the prevention of H. pylori complications by decreasing H. pylori density and gastritis, and for the prevention of H. pylori colonization or re-infection by inhibiting adhesion to gastric epithelial cells. (nih.gov)
Moreover the biosynthetic pathways here identified as responsible for gastric mucosa improved sialylation in response to illness can be exploited as drug focuses on for hindering PF-06687859 bacteria adhesion and counteract the infection chronicity. (bio-cavagnou.info)
During chronic H. pylori infection hosts develop complex immune responses to cope with bacterial persistence that result in a variety of outcomes ranging from peaceful co-existence to detrimental disease. (nimml.org)
Macrophages interact with T helper (Th) cells during infection and release cell-polarizing cytokines such as IL-17 [ 8 ]. (nimml.org)
In addition, H. pylori infection also involves neutrophils and increased antigen presenting activity of dendritic cells (DC) [ 9 ]. (nimml.org)
Currently, the model is able to predict the distinct time-dependent behavior of the three main CD4+ T cells (Th1, Th17 and iTreg) showing an increased Th17 response at the early stage of infection that switches to a Th1 predominance in the chronic phase of the infection. (nimml.org)
Periodontal disease is a chronic bacterial infection that affects the gingiva and bone that supports the teeth. (bvsalud.org)
Foci of infection in the oral cavity arising from chronic periodontitis or chronic periapical abscesses (ie, inflammation and abscess of the tissue attached to the apex of the root) may lead to subacute bacterial endocarditis (BE) and glomerulonephritis (GN). (medscape.com)
Periodontitis is a common chronic bacterial infection of the supporting structures of the teeth. (medscape.com)

instead exogenous galectin-3 increases adhesion to monocytes and macrophages but not epithelial cells. (ox.ac.uk)
1998. Activation of alveolar macrophages and peripheral red blood cells in rats exposed to fibers/particles. (cdc.gov)

Bacterial membrane vesicles dispersion along the cell surface was measured in live Escherichia coli, commensal bacteria common in the human gut. (wikipedia.org)
Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double-blind study. (utivahealth.com)
Other cancer-associated bacterial taxa have been identified, including Escherichia coli strain NC101 and Bacteroides fragilis , each with a proposed mechanism of interaction with colon cancer [ 15 ]. (biomedcentral.com)
Enterohaemorrhagic Escherichia coli O157 : H7 is a bacterial pathogen that can cause haemorrhagic colitis and haemolytic uremic syndrome. (hw.ac.uk)

Membrane vesicle trafficking in eukaryotic animal cells involves movement of biochemical signal molecules from synthesis-and-packaging locations in the Golgi body to specific release locations on the inside of the plasma membrane of the secretory cell. (wikipedia.org)
In this process, the packed cellular products are released or secreted outside the cell, across its plasma membrane. (wikipedia.org)
On the other hand, the vesicular membrane is retained and recycled by the secretory cells. (wikipedia.org)
In prokaryotic, gram-negative bacterial cells, membrane vesicle trafficking is mediated through bacterial outer membrane bounded nano-sized vesicles, called bacterial outer membrane vesicles (OMVs). (wikipedia.org)
This forces the vesicle membrane against the membrane of the target complex (or the outer membrane of the cell) and causes the two membranes to fuse. (wikipedia.org)
Depending on whether the vesicle fuses with a target complex or the outer membrane, the contents of the vesicle are then released either into the target complex or outside the cell. (wikipedia.org)
Budding of MVs directly from plasma membrane as microvesicles released outside the secretory cells. (wikipedia.org)
Exosomes are released eventually due to fusion of this endosome with plasma membrane of cell. (wikipedia.org)
All these types (1-4) of modes of membrane vesicle trafficking, taking place in eukaryotic cells have been explained diagrammatically. (wikipedia.org)
Antibiotic treatment altered vesicle dynamics, vesicle-to-membrane affinity, and surface properties of the cell membranes, generally enhancing vesicle transport along the surfaces of bacterial membranes and suggesting that their motion properties could be a signature of antibiotic stress. (wikipedia.org)
gain access to the cell membrane to initiate invasion ( 9, 10). (researchgate.net)
Here, the adhesion mechanisms of Lactobacillus rhamnosus GG (LGG) surface mutants to a milk component, the milk fat globule membrane (MFGM), were compared using atomic force microscopy (AFM). (uantwerpen.be)
Electron microscopy reveals loss of desmosomes (epithelial intercellular junctions formed by membrane and submembrane protein complexes), breakdown of desmosome-keratin intermediate filament attachment, and perinuclear aggregates of keratin intermediate filaments. (medscape.com)

these data showed that sustained abnormal MUC1 induction accompanies failing epithelial repair, chronic inflammation and kidney fibrosis. (cusabio.com)
CONCLUSIONS: These findings suggest that chronic psychological stress can be an initiating factor in intestinal inflammation by impairing mucosal defenses against luminal bacteria and highlight the importance of mast cells in this process. (mcmaster.ca)
The unique architecture of this newly recognized superlectin correlates with multiple functions including bacterial cell cross-linking, adhesion to human epithelia, and stimulation of inflammation. (qub.ac.uk)
The objective of this proposal was to define mechanisms by which hog barn dust activates epithelial cell PKC and the role of PKC in airway inflammation associated with chronic bronchitis occurring in confinement facility workers and to determine the role of hog barn dust-related lysophosphatidic acid (LPA), an important lipid mediator, in modulating dust effects on PKC and inflammatory responses. (cdc.gov)
We have observed that substances from Gram-positive bacteria (peptidoglycan) and proteases within the dust contribute substantially to airway epithelial inflammation. (cdc.gov)

A leading hypothesis proposes that tubular cell proliferation and differentiation are linked to flow rate and that ciliary dysfunction may thus lead to cystic transformation. (msdmanuals.com)
1994. Mesothelial cell proliferation: A nonspecific response to lung injury associated with fibrosis. (cdc.gov)

Depending on the nature of the adhesion structures, adhesion and migration are either compatible or a trade-off is required for efficient bacterial surface colonization under different conditions. (biorxiv.org)
2010). It may have an effect on bacterial structure, influence the adhesion of bacterial to epithelial cells, and prevent colonization. (interesjournals.org)

The translocation of effector molecules such as CagA and the bacterial cell wall peptidoglycan (PGN) results in the modulation of different sponsor intracellular signaling pathways including activation of the NF-κB (nuclear PF-06687859 element κB) pathway [15 16 induced inflammatory reactions include PF-06687859 the up-regulation of proinflammatory cytokines including IL-8 and TNF-α. (bio-cavagnou.info)
to inhibit the actions of cytokines made by Th1 immune system cells.9 Moreover, a direct impact of just one 1,25(OH)2D3 on B-cell homoeostasis Mouse monoclonal to SNAI1 has been verified.10 Therefore, supplement D may have a job in B-cell-related autoimmune disorders such as for example SLE. (informationalwebs.com)
Epithelial cells within the airways respond to inhaled agents with the release of cytokines that recruit and activate inflammatory cells and expression of molecules that serve as receptors and ligands for interactions with other cells. (cdc.gov)
The integration of pathogen-associated molecular patterns (PAMPs) from microorganisms with their surface receptors in the immune cells, induces the production of several cytokines and chemokines that presents either a pro- and/or anti-inflammatory role by stimulating the secretion of a great variety of antibody subtypes and the activation of mechanisms of controlling the disease, such as the regulatory T cells. (bvsalud.org)

In bacterial pathogenesis, the ectodomain of CD324 mediates bacterial adhesion to mammalian cells, while the cytoplasmic domain is required for internalization. (biolegend.com)
Overall, Bcc Pal mediates host cell attachment and stimulation of cytokine secretion, contributing to Bcc pathogenesis. (cnr.it)
3) Identify mechanisms by which HDE augmentation of epithelial cell PKC in vitro mediates recruitment and adhesion of inflammatory cells to airway epithelium in vitro. (cdc.gov)

Disease development depends on bacterial ability to set up close contact with the gastric epithelial cells and to transfer virulence factors [3]. (bio-cavagnou.info)
Glycan-mediated adhesion of to gastric epithelial cells offers been shown to act as an important result in for translocation of bacterial virulence factors into the sponsor cells [14]. (bio-cavagnou.info)
We have previously demonstrated that induces in human being gastric cell lines the manifestation of β3GnT5 a GlcNAc-transferase PF-06687859 that drives the biosynthesis of the SabA-ligand sialyl-Lex [22]. (bio-cavagnou.info)
Innate immune cells play a decisive role in host fate by enabling high bacterial loads and minimizing the immunological impact of this burden in the gastric mucosa. (nimml.org)
CagA is an effector protein injected into the gastric epithelial cells by a type IV secretion system encoded by the cag pathogenicity island (cagPAI). (nimml.org)
As shown in figure 1, the inflammatory response towards H. pylori is initiated through the interaction between the pathogen lipopolysaccharides (LPS) and the Toll-like receptors (TLR) expressed on gastric epithelial cells [ 6 ]. (nimml.org)

Our results show increased microbial diversity in the tumor microenvironment, with changes in the abundances of commensal and pathogenic bacterial taxa, including Fusobacterium and Providencia . (biomedcentral.com)
This work identifies bacterial taxa significantly correlated with colorectal cancer, including a novel finding of an elevated abundance of Providencia in the tumor microenvironment. (biomedcentral.com)
We also describe the predicted metabolic pathways and enzymes differentially present in the tumor-associated microbiome, and show an enrichment of virulence-associated bacterial genes in the tumor microenvironment. (biomedcentral.com)

The imidazole antibiotic miconazole, that has been shown to inhibit bacterial flavohemoglobin activity, prolonged the DETA/NO-evoked growth inhibition. (biomedcentral.com)
Anaturally occurring probiotic found invaginal fluid that in hibits bacterial adhesion to epithelial cells and produces lactic acid to kill or inhibit many other types of bacteria. (365her.shop)
Considered generally recognized as safe (GRAS) by the Food and Drug Administration and recently approved by the U.S. Dept. of Agriculture for use on fresh beef, ALF can be sprayed onto carcasses to help prevent bacterial contamination during processing or can be applied to a subprimal or finished beef surface prior to final packaging to inhibit bacterial growth and extend shelf life. (ift.org)

The aim of this study was to investigate a berry (wild blueberry, cranberry, and strawberry) polyphenolic fraction, commercialized as OrophenolR, for its antibacterial, anti-biofilm, and anti-adhesion properties on S. mutans. (cranberryinstitute.org)
Can act both as an adhesion and an anti-adhesion protein. (cusabio.com)

Hap involvement in NTHi375-host interaction was shown to be limited, despite promoting bacterial cell adhesion when expressed in H. influenzae RdKW20. (qub.ac.uk)
In intestine of Ws/Ws rats, epithelial function and morphology were unchanged by chronic stress, bacterial-epithelial cell interaction was not demonstrated, and there was no evidence of inflammatory cell infiltration. (mcmaster.ca)
Galectin-3 binds Neisseria meningitidis and increases interaction with phagocytic cells. (ox.ac.uk)
In-cell Western assays confirmed temporal expression of flagella during O157 interaction with epithelium, early expression was suppressed during the later stages of microcolony and attaching and effacing lesion formation. (hw.ac.uk)
We report that bacterial interaction with the host intracellular environment caused significant suppression of regulatory NLRC3 and NLRX1 in a pattern inverse to early regulatory responses. (nimml.org)

This work thus demonstrated a possible competition between LGG adhesion to MFGM and to epithelial intestinal cells. (uantwerpen.be)
This competition could negatively impact the adhesion capacity of LGG to intestinal cells in vivo, but requires further substantiation. (uantwerpen.be)

Finally, analysis of the mechanism by which multimeric alpha-lactalbumin induces apoptosis in transformed epithelial cells could lead to the design of antitumor agents. (lu.se)

CD324, a member of the cadherin superfamily, is a calcium-dependent, transmembrane cell-cell adhesion glycoprotein composed of 4 extracellular cadherin repeats and a highly conserved cytoplasmic tail region with a predicted molecular weight of approximately 100 kD. (biolegend.com)

Milk is the most popular matrix for the delivery of lactic acid bacteria, but little is known about how milk impacts bacterial functionality. (uantwerpen.be)
How twitching bacteria resolve the fundamental contradiction between adhesion and migration is unknown. (biorxiv.org)
In the case of bacteria, strong adhesion to surfaces is required for the formation of mechanically robust biofilms. (biorxiv.org)
The enzyme flavohemoglobin, coded by the hmp gene, is involved in protecting bacterial cells from the toxic effects of NO and represents a potentially interesting target for development of novel treatment concepts against resistant uropathogenic bacteria. (biomedcentral.com)

Bacterial pathogenicity relies on both firm surface adhesion and cell dissemination. (biorxiv.org)

To prevent UTIs, inhibition of bacterial adhesion to epithelial cell lining is proven with 36 mg of PAC (proanthocyanidins Type A) a day. (utivahealth.com)

Cardinal signs of resolution are: (1) limitation/cessation of PMN infiltration, (2) sequestration and counter-regulation of pro-inflammatory chemical mediators, (3) apoptosis of PMN and removal (e.g., by efferocytosis), (4) clearance of pathogens, inflammatory stimuli, and cell debris, and (5) tissue repair. (frontiersin.org)
In a different study, in which researchers systematically analyzed mutations identical to those found in patients with Darier disease, mutant SERCA2 protein aggregates were found to cause stress to the endoplasmic reticulum, subsequently inducing cell apoptosis. (medscape.com)

Microbial exposure during early life has persistent effects on natural killer T cell function. (nature.com)
Stronganti-parasitic and anti-microbial that fights systemic yeast infections and bacterial vaginosis. (365her.shop)
As a result of recent advances in culture-independent measurements of microbial communities, we know that the human gut is host to roughly a thousand different bacterial species [ 2 ]. (biomedcentral.com)
Bacteriostasic effect is enhanced when LF binds to a microbial cell surface (Dalamastri et al. (ift.org)

The berry polyphenolic preparation dose-dependently inhibited S. mutans biofilm formation while not reducing bacterial growth. (cranberryinstitute.org)

Some of these animal hosted Campylobacter species, such as Campylobacter jejuni and Campylobacter coli , can cause acute bacterial gastroenteritis in humans through consumption of contaminated food or water ( Galanis, 2007 ). (frontiersin.org)
The adhesion test for the E.coli was applied by method of slide hemagglutination of erythrocyte cells ( Iwahi et al. (interesjournals.org)

It presents a functional unit of a physical barrier consisting of a mucus layer and a monolayer of epithelial cells and of a mucosal lymphoid system that together efficiently discriminate between pathogenic and commensal microorganisms 16 . (nature.com)
In addition to bacterial organisms, oral microorganisms can include fungal, protozoal, and viral species. (medscape.com)

It is also recommended using EDTA-based solutions for dissociating attachment-dependent cell lines. (biolegend.com)
Attachment to surfaces is mediated, besides T4P, by passive adhesive forces acting on the cell body. (biorxiv.org)
Wild-type cells sacrifice migration speed for robust surface attachment by maintaining a low number of active pili. (biorxiv.org)
a) Migrating cells under mechanical shear have to balance attachment and detachment to remain at the surface. (biorxiv.org)
0001), confirming that Pal plays a direct role in host cell attachment. (cnr.it)

Our results indicate that high d - mannose concentrations have no effect on bacterial growth and do not interfere with the activity of different antibiotics . (green-infos.com)

In +/+ rats, chronic stress induced barrier dysfunction in the ileum and colon (increased macromolecular permeability and depletion of mucus) and ultrastructural changes in epithelial cells (enlarged mitochondria and presence of autophagosomes) associated with bacterial adhesion and penetration into enterocytes. (mcmaster.ca)

Conjugate vaccine technology, where a polysaccharide antigen is coupled chemically to a protein carrier, either by direct linkage or by indirect coupling via diamino spacer molecules, can render the PS specific immune response T cell dependent. (bmj.com)
With the help of T cell derived factors, the antigen specific B cells produce a much enhanced antibody response. (bmj.com)

Les anticorps du jaune d'œuf de poule (IgY), production et utilisation en immunisation passive contre les infections entériques bactériennes : une revue. (ac.be)
Unfortunately poultry meat is one of the major sources of food borne bacterial infections in humans such as Salmonellosis (Mayrhofer et al. (ac.be)
Nitric oxide (NO) is produced as part of the host immune response to bacterial infections, including urinary tract infections. (biomedcentral.com)

Nasal epithelial PAFR was assessed in non-vaping controls, and in adults before and after 5 min of vaping. (ersjournals.com)
There was no difference in baseline nasal epithelial PAFR expression between vapers (n=11) and controls (n=6). (ersjournals.com)

Kaposi sarcoma (KS) is a neoplasm of vascular endothelial and lymphoreticular cells that can involve the skin and numerous visceral organs. (medscape.com)
This is followed by polymorphonuclear neutrophil (PMN) recruitment, adhesion to vascular endothelial cells, diapedesis (or transmigration), and accumulation or swarming. (frontiersin.org)

Our results show that CNCM I-3690 can (i) physically maintain modulated goblet cells and the mucus layer and (ii) counteract changes in local and systemic lymphocytes. (nature.com)

Formation of the characteristic attaching and effacing (A/E) lesion on the surface of infected cells causes significant remodelling of the host cell surface, however limited information is available about changes at the protein level. (imperial.ac.uk)
The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. (cusabio.com)
It is a glycan binding protein which can exert its functions within cells or exogenously by binding cell surface ligands, acting as a molecular bridge or activating signalling pathways. (ox.ac.uk)
Dozens of bacterial factors are involved in H. pylori molecular pathogenesis (i.e. flagella, urease, catalase, neutrophil-activating protein Nap-A, vacA and cagA). (nimml.org)
Previously, we observed that hog barn dust extract (HDE) augments human airway epithelial protein kinase C (PKC) activation, resulting in IL-8 and IL-6 release and increased ICAM-1 expression, mediating inflammatory cell adhesion to airway epithelium in vitro. (cdc.gov)
The investigators found that the resultant transfected cells showed defects in ATP2A2 protein expression (15 mutants), ATP hydrolysis (29 mutants), calcium transport (4 mutants), and calcium binding and kinetics (3 mutants). (medscape.com)

Significantly, functional annotation revealed that the up-regulated genes were significantly over-represented in cell death pathways Finally, we show that S-adenosyl-L-methionine (AdoMet), a commercially available, FDA-approved dietary supplement, enhances the viability of S. boulardii in acidic environments, most likely by preventing programmed cell death. (biomedcentral.com)

T47-D cell lysate, colon cancer lysate, Human breast carcinoma tissue, Human normal breast tissue. (abcam.com)
However, it has rarely been considered that human milk may also contain substances bioactive toward host cells. (lu.se)
Human colon carcinoma cell line HT-29 was stained with CD324 (clone 67A4) APC/Fire™ 750 (filled histogram) or mouse IgG1, κ APC/Fire™ 750 isotype control (open histogram). (biolegend.com)
FimH functionality was analyzed by yeast agglutination and human bladder cell adhesion assays. (green-infos.com)
Das D, Tapryal N, Goswami S.K., Fox P.L, and Mukhopadhyay C.K. Regulation of Ceruloplasmin in human hepatic cells by redox active copper: Identification of a novel AP-1 site in ceruloplasmin gene. (jnu.ac.in)
A study found that consuming maltodextrin increased bacterial adhesion to human intestinal epithelial cells and enhanced E. The value of corrected experimental LDH release was calculated by subtracting the value of spontaneous LDH release from effector cells at corresponding dilutions. (ucademix.com)

It may also invade and proliferate within heart and coronary artery endothelial cells, and, along with Streptococcus sanguis, it may also induce platelet aggregation associated with thrombus formation. (medscape.com)

Deletion of downregulated nonessential genes and upon NrdR overexpression led to diminished bacterial development and fitness recommending an additional function for NrdR in regulating various other genes. (immune-source.com)
Genes involved with DNA and ATP biogenesis play an integral function in DNA duplication and cell department [1]. (immune-source.com)

When miconazole was combined with polymyxin B nonapeptide (PMBN), in order to increase the bacterial wall permeability, DETA/NO caused a prolonged bacteriostatic response that lasted for up to 24 h. (biomedcentral.com)

Antibiotic sensitivity patterns showed concordance of bacterial cultures from dental plaque and oropharyngeal cavity in 13 patients. (who.int)

On the other hand, the use of plant cell cultures for the more basic characterization of plant functions is rather limited due to the difficulties associated with functional differentiation in cell cultures. (go.jp)

ABSTRACT Optical density is a proxy of total biomass concentration and is commonly used for measuring the growth of bacterial cultures. (microbial-ecology.net)
NO inhibits growth of a wide variety of gram-negative and gram-positive bacterial species [ 1 ]. (biomedcentral.com)
Vasopressin promotes cell growth and fluid secretion via the cyclic AMP pathway, which leads to increase in the size and number of cysts in polycystic kidney disease. (msdmanuals.com)

Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. (cusabio.com)

Right here we profile bacterial destiny under circumstances of overexpression and deletion of NrdR in appearance causes a substantial decrease in bacterial development and fitness also at normal temperature ranges and causes lethality at raised temperature ranges. (immune-source.com)

Bacterial species are usually not harmful to their hosts, although there are exceptions. (frontiersin.org)
We provide evidence that suggests that S. boulardii undergoes programmed cell death (PCD) in acidic environments, which is accompanied by the generation of reactive oxygen species and the appearance of caspase-like activity. (biomedcentral.com)

Galectin-3 is expressed and secreted by immune cells and has been implicated in multiple aspects of the inflammatory response. (ox.ac.uk)
Reports claim that sufferers with SLE possess modifications in steroid hormone fat burning capacity.11 It's been demonstrated Nifuroxazide that oestrogen results are mediated through oestrogen receptors and probably , that are expressed in an array of immune system cells and so are involved with adaptive and innate immune system responses. (informationalwebs.com)

Our data indicate that normal and inflamed skin harbor distinct phageomes and suggest a causative relationship between changing viral and bacterial communities as a driver of skin pathology. (microbial-ecology.net)

We propose that BC2L-C binds to the bacterial surface in a mannose/heptose-dependent manner via the C-terminal domain. (qub.ac.uk)

the host epithelial cell ( 7, 8). (researchgate.net)
Since oxidative stress in airway cells increases platelet-activating factor receptor (PAFR) expression, and PAFR is co-opted by pneumococci to adhere to host cells, we hypothesised that E-cigarette vapour increases pneumococcal adhesion to airway cells. (ersjournals.com)
To establish firm adhesion, pneumococci co-opt host-expressed platelet-activating factor receptor (PAFR), and then use the receptor as a Trojan horse to enter airway cells as the receptor is internalised [ 7 ]. (ersjournals.com)
These outcomes suggest that raised appearance of NrdR is actually a suitable methods to retard bacterial development and virulence as its raised expression decreases bacterial fitness and impairs web host cell adhesion. (immune-source.com)
Cell Host Microbe 3 , 213-223 (2008). (nature.com)
Alterations of this bacterial community are correlated with host health, including diseases ranging from diabetes and obesity to Crohn's disease and arteriosclerosis [ 3 ]. (biomedcentral.com)
Our data suggest that mechanisms of mononuclear phagocyte response to H. pylori occur sequentially and may depend on the location of the bacterium with respect to the host cell. (nimml.org)
MW) chemicals interact with host cells and molecules and In our daily life, we are confronted with a plethora of natural influence biologic processes such as signal transduction. (cdc.gov)

2) Establish how HDE-associated lysophosphatidic acid (LPA) modulates HDE-induced epithelial cell PKC activity and IL-8/IL-6 release. (cdc.gov)
4) Determine how HDE modulates airway epithelial PKC activation and inflammatory responses in vivo utilizing an animal model of exposure, including testing the potential role of LPA. (cdc.gov)

Anatomy56

Organisms19

Diseases8

Chemicals and Drugs84

Analytical, Diagnostic and Therapeutic Techniques and Equipment27

Phenomena and Processes46

Disciplines and Occupations1

Technology, Industry, Agriculture9

Information Science3

Molecule3

Airway epithelial cells2

Proteins18

Adherence6

Strains6

Infection21

Macrophages2

Escherichia4

Membrane13

Inflammation5

Proliferation2

Colonization2

Cytokines4

Mediates3

Gastric6

Tumor3

Inhibit3

Anti-adhesion2

Interaction5

Intestinal cells2

Induces1

Extracellular1

Bacteria4

Pathogenicity1

Inhibition1

Apoptosis2

Microbial4

Biofilm1

Coli2

Microorganisms2

Attachment5

Effect on bacterial1

Chronic1

Antigen2

Infections3

Nasal2

Vascular endothelial2

Mucus1

Protein6

Significantly1

Human6

Endothelial1

Genes2

Permeability1

Antibiotic1

Differentiation1

Growth3

Regulates1

Decrease1

Species2

Immune2

Viral1

Binds1

Host8

Modulates2