• Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
  • Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
  • Mixed mesenchymal and epithelial tumors are of Mullerian origin. (cytojournal.com)
  • To evaluate their relationship to clinical tumors, we determined phenotypic relationships among these carcinomas, other murine models of breast cancer, and features of luminal tumors in women. (biomedcentral.com)
  • We compared levels of transcripts in the ERα-associated "luminal" signature that defines this subtype of tumors in women and transcripts enriched in various mammary epithelial lineages to other well-studied genetically modified murine models of breast cancer. (biomedcentral.com)
  • The remaining 44% were composed of carcinomas not otherwise specified and a variety of uncommon tumors: large cell, clear cell, solid, bronchoalveolar, adenosquamous, epithelial hemangioendothelioma, oat cell, carcinoid, small cell and mucinous histological types. (biomedcentral.com)
  • According to the most recent World Health Organization classification of breast tumors, the histologic types of MBC are low-grade adenosquamous carcinoma, fibromatosis-like metaplastic carcinoma, spindle cell carcinoma, squamous cell carcinoma, metaplastic carcinoma with heterologous mesenchymal differentiation, and mixed metaplastic carcinoma. (dirjournal.org)
  • Breast cancers usually are epithelial tumors of ductal or lobular origin. (medscape.com)
  • Gastric carcinoma comprises more than 90% of all gastric malignant tumors. (poznayka.org)
  • Although OPN expression was identified in a good number of bladder, prostate, and brain tumors, the majority of 6 skin cancers, 11 of 14 salivary gland cancers, 2 thyroid carcinomas, and 23 of 26 breast cancers revealed low OPN positivity or were negative. (aacrjournals.org)
  • Most adenoid cystic carcinomas have been described as hormone receptor-negative by biochemical and immunohistochemical analysis with occasional tumors positive for estrogen and/or progesterone receptors at relatively low levels ( 8 , 9 , 10 ). (basicmedicalkey.com)
  • In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
  • Ductal carcinoma in situ (DCIS) is noninvasive breast cancer that is limited to the inside of the ducts of the breast. (medscape.com)
  • Increased use of screening mammography has resulted in a dramatic increase in the detection of ductal carcinoma in situ (DCIS). (medscape.com)
  • Lobular carcinoma in situ (LCIS), which is not considered a malignancy, arises from the lobule at the terminal end of the duct and shows a rather diffuse distribution throughout the breast, which explains its presentation as a nonpalpable mass in most cases (see the images below). (medscape.com)
  • carcinoma in situ in the stomach (a state of severe cellular atypia or dysplasia, without invasion across the basement membrane of the glands). (poznayka.org)
  • About one in every five new breast cancer cases is ductal carcinoma in situ. (breastcancertalk.net)
  • Patients with ductal carcinoma in situ are typically at higher risk for seeing their cancer return after treatment , although the chance of a recurrence is less than 30 percent. (breastcancertalk.net)
  • A recurrence of ductal carcinoma in situ would require additional treatment. (breastcancertalk.net)
  • Currently, the long-term survival rate for women with ductal carcinoma in situ is nearly 100 percent. (breastcancertalk.net)
  • Most of the cervical epithelial neoplasms and their precursors occur at the squamocolumnar junction or within the transformation zone. (cytojournal.com)
  • Microscopically, fungating or polypoid carcinomas are well-differentiated adenocarcinomas, commonly papillary type. (poznayka.org)
  • Other histologic subtypes include adenosquamous, clear cell, and papillary serous carcinomas. (medscape.com)
  • WHO 2022 landscape of papillary and chromophobe renal cell carcinoma. (who.int)
  • Commonly seen subtypes include squamous cell carcinoma, spindle cell carcinoma, and metaplastic carcinoma with heterologous mesenchymal differentiation. (dirjournal.org)
  • 2 In a large international multicenter study of 405 patients with histologic confirmation of MBC, spindle cell (34%) was the most common subtype in the Western series, and squamous cell (34%) was the most common subtype in the Asian series, followed by metaplastic carcinoma with heterologous mesenchymal differentiation in both series (29% and 24%, respectively). (dirjournal.org)
  • Large cell neuroendocrine carcinoma (LCNEC) is now recognized as a histologically high grade non small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (ersjournals.com)
  • Finally, a new class was defined called carcinoma with pleomorphic, sarcomatoid, or sarcomatous elements, which brings together a number of proliferations characterized by a spectrum of epithelial to mesenchymal differentiation. (ersjournals.com)
  • Metaplastic breast cancer (MBC) is a rare subtype of invasive breast cancer characterized by mixed epithelial and mesenchymal differentiation. (dirjournal.org)
  • Focal sebaceous and adenosquamous differentiation are variably present ( 4 ). (basicmedicalkey.com)
  • Macroscopically, the lesions of early gastric carcinoma may have 3 patterns-superficial, polypoid and ulcer-associated. (poznayka.org)
  • Inspissated secretion and stromal fragments from benign lesions or other forms of carcinoma may be mistaken for cylindromatous material in needle core biopsy samples. (basicmedicalkey.com)
  • It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA . (lookformedical.com)
  • Approximately 95% of these malignancies are carcinomas of the endometrium . (medscape.com)
  • Carcinomas, malignancies of epithelial tissue, account for 80 to 90 % of all cancer cases since epithelial tissues are most abundantly found in the body from being present in the skin to the covering and lining of organs and internal passageways, such as the gastrointestinal tract. (solutionpharmacy.in)
  • It is mainly subcategorized into adenocarcinomas, squamous cell carcinomas, large cell carcinomas and several other types that occur less frequently include adeno squamous carcinomas, and sarcomatoid carcinomas. (juneaunewsupdates.com)
  • Six genes carrying DNVs were associated with human developmental disorders involving epithelial, connective or bone morphologies ( PXDN, RTEL1, ANKRD11, MAP2K1, CYLD, ACAN) and four linked with cholangio- and hepatocellular carcinomas (PIK3CA, TLN1 CYLD, MAP2K1) . (biomedcentral.com)
  • Histologic predictors of response to neoadjuvant PD1 inhibitor therapy in advanced stage HPV-negative head and neck squamous cell carcinomas. (headandneckpathology.com)
  • The term cylindroma, previously used interchangeably with adenoid cystic carcinoma, refers to the histologic appearance that suggests entwined cylinders of stroma and epithelial cells. (basicmedicalkey.com)
  • Shrinkage artifacts, a relatively frequent occurrence in histologic sections of adenoid cystic carcinoma, may be mistaken for lymphatic tumor emboli. (basicmedicalkey.com)
  • This type of carcinoma is categorised into two main groups based on the tumour's characteristics: pure epithelial and mixed epithelial and mesenchymal groups. (klarity.health)
  • The expression of hepatocyte growth factor (HGF) and changes in the epithelial-mesenchymal transition (EMT) status including the expression of E-cadherin and γ-catenin as epithelial markers, and those of vimentin and fibronectin as mesenchymal markers, were evaluated by immunohistochemistry. (iiarjournals.org)
  • NSCLC can be defined as any type of epithelial lung cancer other than SCLC. (juneaunewsupdates.com)
  • High cytoplasmic OPN staining was observed in 100% of gastric carcinomas, 85% of colorectal carcinomas, 82% of transitional cell carcinomas of the renal pelvis, 81% of pancreatic carcinomas, 72% of renal cell carcinomas, 71% of lung and endometrial carcinomas, 70% of esophageal carcinomas, 58% of squamous cell carcinomas of the head and neck, and 59% of ovarian carcinomas. (aacrjournals.org)
  • Kasuganti D, Cimbaluk D, Gattuso P. Lymph node metastasis of large-cell carcinoma of the lung in a seventeen-year-old patient: diagnosis by fine-needle aspiration. (rush.edu)
  • Macroscopically, ulcerative carcinomas are poorly-differentiated adenocarcinomas, which invade deeply into the stomach wall. (poznayka.org)
  • Approximately eighty percent of endometrial carcinomas are endometrioid adenocarcinomas. (medscape.com)
  • MBC tends to have a more aggressive clinical presentation, higher metastatic potential, higher rates of local recurrence, and a worse prognosis compared with invasive breast carcinoma of no special type. (dirjournal.org)
  • Squamous cell carcinoma tends to reveal an irregularly-shaped cystic mass with spiculated margins, while spindle cell carcinoma is more likely to show benign imaging features, such as an oval shape and circumscribed margins. (dirjournal.org)
  • Less than 0.1% of mammary carcinomas have an adenoid cystic growth pattern. (basicmedicalkey.com)
  • Adenoid cystic carcinoma occurs in adult women throughout the age distribution of mammary carcinoma, with patients between ages 25 and 80 and a reported mean age that varies from 50 to 63 years. (basicmedicalkey.com)
  • Adenoid cystic carcinoma usually presents as a discrete firm mass. (basicmedicalkey.com)
  • Many adenoid cystic carcinomas are circumscribed or nodular grossly, but the majority have an invasive growth pattern microscopically ( Fig. 17.1 ). (basicmedicalkey.com)
  • Adenoid cystic carcinoma consists of a mixture of proliferating glands (adenoid component) and stromal or basement membrane elements ("pseudoglandular" or cylindromatous component). (basicmedicalkey.com)
  • Because of this intratumoral heterogeneity, adenoid cystic carcinoma may be difficult to recognize in a needle core biopsy specimen if a characteristic sample has not been obtained ( Figs. 17.2 , 17.3 ). (basicmedicalkey.com)
  • The microscopic growth patterns of mammary adenoid cystic carcinoma have been described as cribriform, solid, glandular (tubular), reticular (trabecular), and basaloid. (basicmedicalkey.com)
  • 5 This is why axillary lymph node metastasis is rare, while the lungs and bones are the most common sites for MBC to metastasize, which may explain why patients usually present in the advanced stages more frequently than with invasive breast carcinoma of no special type (IBC-NST). (dirjournal.org)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
  • Women with low-grade DCIS are at higher risk of developing invasive breast cancer than women without DCIS, but are less likely to have a recurrence of the breast carcinoma or to develop new cancers than women with higher-grade DCIS. (medscape.com)
  • Our studies demonstrate that prolactin can promote diverse carcinomas in mice, many of which resemble luminal breast cancers, providing a novel experimental model to examine the pathogenesis, progression and treatment responsiveness of this tumor subtype. (biomedcentral.com)
  • Adenosquamous carcinoma is defined as a tumor in which both glandular and squamous elements are histologically malignant. (biomedcentral.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • A malignant epithelial tumor with a glandular organization. (lookformedical.com)
  • carcinoma contains abundant pools of mucin in which are seen a small number of tumor cells, sometimes having signet-ring appearance. (poznayka.org)
  • Abundant stromal material in other parts of the tumor can produce a pattern that can be mistaken for scirrhous carcinoma. (basicmedicalkey.com)
  • A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. (lookformedical.com)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (lookformedical.com)
  • An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. (lookformedical.com)
  • An epithelial neoplasm characterized by unusually large anaplastic cells. (uchicago.edu)
  • Primary and recurrent head and neck squamous carcinomas are strikingly different regarding their immune microenvironment. (headandneckpathology.com)
  • OBJECTIVES: I. Evaluate the efficacy of paclitaxel and carboplatin with amifostine on progression free survival and overall survival in patients with metastatic or recurrent epithelial endometrial carcinoma not amenable to surgery or radiotherapy. (knowcancer.com)
  • Recurrent giant cell carcinoma of the bladder. (uchicago.edu)
  • Adenosquamous carcinoma of the oral cavitiy: a rare epithelial malignancy. (creighton.edu)
  • Although some published studies have analyzed and discussed adenosquamous carcinomas, hybrid malignancy of the ampulla of Vater has rarely been discussed thus far in the literature. (biomedcentral.com)
  • Similarly, under Carcinoma, specific renamed or deleted in later revisions of tumour classifications. (who.int)
  • IHC analysis of head and neck squamous cell carcinoma using anti-alpha-Smooth Muscle Actin antibody. (progen.com)
  • As major energy source in maintaining renal physiological functions, tubular epithelial cells with decreased fatty acid oxidation play a key role in renal fibrosis development. (bvsalud.org)
  • In this study, we evaluated the therapeutic value of inorganic nitrate treatment on development of kidney fibrosis and investigated underlying mechanisms including regulation of lipid metabolism in tubular epithelial cells. (bvsalud.org)