• Genetic
  • LGI1, a secreted presynaptic protein, has mystified the field for over a decade, given that we have problems understanding how a highly localized form of epilepsy can be caused by a global genetic defect. (epilepsygenetics.net)
  • Linkage works beautifully in very large families and pretty much all the epilepsy genes identified at the turn of the millennium stem from large families where linkage analysis was applied to narrow down the genetic interval where a given gene is hidden. (epilepsygenetics.net)
  • form
  • In a recent study in the American Journal of Human Genetics, reelin takes on a new role as a novel gene for a familial form of lateral temporal lobe epilepsy. (epilepsygenetics.net)